1,493 research outputs found
Die Sparkassen und die staatliche Sparförderung
No full textKopper C. Die Sparkassen und die staatliche Sparförderung. In: Schulz G, ed. Die Entstehung der modernen Sparkasse. Sparkassen in der Geschichte / Forschung. Vol 23. Stuttgart: S-Communications Services GmbH; 2022: 165-180
150 Jahre Brenntag. Von Berlin in die Welt
No full textKopper C, Tilly S. 150 Jahre Brenntag. Von Berlin in die Welt. München: Siedler; 2024
IceCube-Gen2: A Vision for the Future of Neutrino Astronomy in Antarctica
No full text20 pages, 12 figures. Address correspondence to: E. Blaufuss, F. Halzen, C. Kopper (Changed to add one missing author, no other changes from initial version.)20 pages, 12 figures. Address correspondence to: E. Blaufuss, F. Halzen, C. Kopper (Changed to add one missing author, no other changes from initial version.)20 pages, 12 figures. Address correspondence to: E. Blaufuss, F. Halzen, C. Kopper (Changed to add one missing author, no other changes from initial version.)The recent observation by the IceCube neutrino observatory of an astrophysical flux of neutrinos represents the "first light" in the nascent field of neutrino astronomy. The observed diffuse neutrino flux seems to suggest a much larger level of hadronic activity in the non-thermal universe than previously thought and suggests a rich discovery potential for a larger neutrino observatory. This document presents a vision for an substantial expansion of the current IceCube detector, IceCube-Gen2, including the aim of instrumenting a volume of clear glacial ice at the South Pole to deliver substantial increases in the astrophysical neutrino sample for all flavors. A detector of this size would have a rich physics program with the goal to resolve the sources of these astrophysical neutrinos, discover GZK neutrinos, and be a leading observatory in future multi-messenger astronomy programs
Die Reichsbahn und der Strafvollzug in der DDR. Häftlingszwangsarbeit und Gefangenentransport in der SED-Diktatur
No full textKill S, Kopper C, Peters J-H. Die Reichsbahn und der Strafvollzug in der DDR. Häftlingszwangsarbeit und Gefangenentransport in der SED-Diktatur. Essen: Klartext; 2016
Verkehrspolitische Weichenstellungen nach 1945
No full textKopper C. Verkehrspolitische Weichenstellungen nach 1945. In: Schott D, Klein S, eds. Mit der Tram ins nächste Jahrtausend. Geschichte, Gegenwart und Zukunft der elektrischen Straßenbahn. Essen: Klartext-Verlag; 1998: 59-68
Examination of parasites as a treatment for inflammatory bowel disease using murine models
No full textABSTRACTEXAMINATION OF PARASITES AS A TREATMENT FOR INFLAMMATORY BOWEL DISEASE USING MURINE MODELSByJamie Jennifer Kopper Inflammatory Bowel Disease (IBD) is a serious, life-threatening chronic inflammatory disease of the gastro-intestinal tract that has been reported to affect 1.1 million adults in the US. Patients with IBD often become refractory to traditional treatments which include antibiotics, immune modulators and corticosteroids. IBD can result in a life-threatening condition and lead to the necessitation of surgical interventions such as for bowel resections. In 2003 Dr. Joel Weinstock proposed using Trichuris suis as a treatment for inflammatory bowel disease in patients who were otherwise refractory to standard treatments and subsequently published the results of two small-scale clinical trials. Here, he reported that T. suis resulted in amelioration of clinical signs of disease in many patients and no adverse side effects. Despite these positive results, the mechanism(s) by which T. suis improved patient outcomes remains unknown. In this work we set forth to address possible mechanisms, and to investigate the possibility of adverse side effects due to T. muris infections in a murine model. We addressed the hypothesis that infections with T. muris alters the colonic microbiota in mice, which may serve as one mechanism to explain the improvement observed in the human patients treated with this worm. We found that C57 BL/6 IL-10-/- mice infected with T. muris had sex and dose dependent morbidity and mortality. Additionally, these infections resulted in severe peritonitis with or without gastrointestinal perforations in some mice. In a subsequent experiment C57 BL/6 IL-10-/- mice infected with T. muris were concurrently treated with prednisolone or metronidazole, neither of which resulted in a significant decrease in mortality when compared to the untreated infected mice. Finally we infected C3H/HeJ and C3Bir IL-10-/- mice, which are predisposed to developing a spontaneous colitis, with T. muris to test our hypothesis that infections with T. muris would change the colonic microbiota. Using Terminal Restriction Fragment Length Polymorphisms (TRFLPs) we determined that mice infected with T. muris had significantly different proximal colon microbial microbiota when compared to uninfected mice. To further assess the effects of colitis without T. muris infections on proximal colon microbiota we obtained samples from C3Bir IL-10-/- mice within our breeding colony who developed spontaneous colitis and compared them to C3Bir IL-10-/- mice without colitis. From this study we found that overall there were no differences, as assessed using TRFLP, between the two groups. From the entirety of this work we conclude that T. muris has the possibility of causing adverse side effects in some individuals, which could include gastrointestinal perforations and peritonitis, particularly those who are deficient in IL-10. Additionally, we concluded that T. muris does result in changes in the structure of the proximal colon microbiota, which may be one mechanism through which it worked as a treatment for IBD in human patients.Thesis (Ph. D.)--Michigan State University. Cell and Molecular Biology, 2011Includes bibliographical reference
Essays in the art and theory of translation /
No full textInhoudsopgave : -- INTRODUCTION -- Honoring Walter Arndt (Richard Sheldon Walter Arndt: A Bibliography -- SECTION I: TRANSLATION, CULTURE AND TRANSLATABILITY -- Kraut und Rüben, Choux et navets, Kaposzta és répak (Marianne Hirsch) -- S(t)imulating Chic: The Aestheticization of Post-Soviet Russia (Helena Goscilo) -- Formal Dress Not Required: The American Academy's Translation of Russian Formalism (John M. Kopper) -- Translating the Untranslatable (Lenore A. Grenoble) -- Matters of Non-equivalence: Egyptianizing French Literature (Carol Bardenstein) -- SECTION II: TRANSLATION, LITERATURE AND WRITERS -- Reminiscences of a Translator from the Modern Greek (Peer Bien) -- Recasting K.: A Translator Approaches The Castle (Mark Harman) -- When Physicists are Lyricists: On Translating the Strugatskys' Monday Starts on Sunday (Yvonne Howell) -- A Source for Pushkin's The Snowstorm (Antonia Glasse) -- Problems in the English Translations of Anna Karenina (Richard Sheldon) -- SECTION III: TRANSLATION AND POETICS -- Wine and Vinegar - On the Translatability of Poetry (Efim Etkind) -- Apocalypse and the Poetics of the Name 'John' in the Little Tragedies (Nathan Longan) -- Marina Tsvetaeva in English: Notes of a Verse Translator (Robin Kemball) -- To and from Autumn: Pasternak's Translations of Keats (Barry P. Scherr) -- Mandelshtam and Celan on Poetic Address (Henry Pickford)Inhoudsopgave : -- INTRODUCTION -- Honoring Walter Arndt (Richard Sheldon Walter Arndt: A Bibliography -- SECTION I: TRANSLATION, CULTURE AND TRANSLATABILITY -- Kraut und Rüben, Choux et navets, Kaposzta és répak (Marianne Hirsch) -- S(t)imulating Chic: The Aestheticization of Post-Soviet Russia (Helena Goscilo) -- Formal Dress Not Required: The American Academy's Translation of Russian Formalism (John M. Kopper) -- Translating the Untranslatable (Lenore A. Grenoble) -- Matters of Non-equivalence: Egyptianizing French Literature (Carol Bardenstein) -- SECTION II: TRANSLATION, LITERATURE AND WRITERS -- Reminiscences of a Translator from the Modern Greek (Peer Bien) -- Recasting K.: A Translator Approaches The Castle (Mark Harman) -- When Physicists are Lyricists: On Translating the Strugatskys' Monday Starts on Sunday (Yvonne Howell) -- A Source for Pushkin's The Snowstorm (Antonia Glasse) -- Problems in the English Translations of Anna Karenina (Richard Sheldon) -- SECTION III: TRANSLATION AND POETICS -- Wine and Vinegar - On the Translatability of Poetry (Efim Etkind) -- Apocalypse and the Poetics of the Name 'John' in the Little Tragedies (Nathan Longan) -- Marina Tsvetaeva in English: Notes of a Verse Translator (Robin Kemball) -- To and from Autumn: Pasternak's Translations of Keats (Barry P. Scherr) -- Mandelshtam and Celan on Poetic Address (Henry Pickford)Met bibliografische verwijzinge
Accuracy of ultrasound-based (BAT) prostate-repositioning: A three-dimensional on-line fiducial-based assessment with cone-beam computed tomography
No full textPurpose: To assess the accuracy of ultrasound-based repositioning (BAT) before prostate radiation with fiducial-based three-dimensional matching with cone-beam computed tomography (CBCT). Patients and Methods: Fifty-four positionings in 8 patients with I-125 seeds/intraprostatic calcifications as fiducials were evaluated. Patients were initially positioned according to skin marks and after this according to bony structures based on CBCT. Prostate position correction was then performed with BAT. Residual error after repositioning based on skin marks, bony anatomy, and BAT was estimated by a second CBCT based on user-independent automatic fiducial registration. Results: Overall mean value (MV +/- SD) residual error after BAT based on fiducial registration by CBCT was 0.7 +/- 1.7 mm in x (group systematic error [M] = 0.5 mm; SD of systematic error [Sigma] = 0.8 mm; SD of random error [sigma] 1.4 mm), 0.9 +/- 3.3 mm in y (M = 0.5 mm, Sigma = 2.2 mm, sigma = 2.8 mm), and - 1.7 +/- 3.4 turn in z (M = - 1.7 mm, Sigma = 2.3 mm, sigma = 3.0 mm) directions, whereas residual error relative to positioning based on skin marks was 2.1 +/- 4.6 mm in x (M = 2.6 mm, Sigma = 3.3 mm, sigma = 3.9 mm), -4.8 +/- 8.5 mm in y (M = -4.4 mm, Sigma = 3.7 mm, sigma = 6.7 mm), and -5.2 +/- 3.6 mm in z (M = -4.8 mm, Sigma = 1.7 mm, sigma = 3.5mm) directions and relative to positioning based on bony anatomy was 0 +/- 1.8 mm in x (M = 0.2 mm, Sigma = 0.9 mm, sigma = 1.1 mm), -3.5 +/- 6.8 mm in y (M = -3.0 mm, Sigma = 1.8 mm, sigma = 3.7 mm), and -1.9 +/- 5.2 mm in z (M = -2.0 mm, Sigma = 1.3 mm, sigma = 4.0 mm) directions. Conclusions: BAT improved the daily repositioning accuracy over skin marks or even bony anatomy. The results obtained with BAT are within the precision of extracranial stereotactic procedures and represent values that can be achieved with several users with different education levels. If sonographic visibility is insufficient, CBCT or kV/MV portal imaging with implanted fiducials are recommended. (C) 2008 Elsevier Inc
« Le recensement est l’infrastructure informationnelle du pays » : le recensement de 2020 et les controverses techno-politiques de sa mise en œuvre
No full textCet article explore les controverses techno-politiques liées à la mise en œuvre du recensement de 2020 au Brésil. Des entretiens et des recherches documentaires ont permis de cartographier les débats techno-moraux et les transformations sociotechniques de deux de ses dispositifs : le questionnaire et le budget. Cet abord a permis de mettre en évidence l’émergence d’une forme d’activisme portée par la mobilisation des experts. Le texte conclut en interprétant le recensement comme une infrastructure informationnelle qui inscrit, imagine et stabilise des idéaux pour le futur au moyen des chiffres.Explora-se as controvérsias tecnopolíticas da execução do censo populacional de 2020 no Brasil. Através de entrevistas e pesquisa documental, mapeia-se as disputas tecnomorais e transformações sociotécnicas de dois dispositivos censitários: o questionário e o orçamento. Isso permite captar a emergência de uma forma de ativismo encabeçada pela mobilização de experts. Conclui-se pensando o censo como infraestrutura informacional que inscreve, imagina e estabiliza ideais de futuridade via números.This article explores the techno-political controversies related to the implementation of the 2020 census in Brazil. Through interviews and documentary research, I have mapped the techno-moral debates and the socio-technical transformations of two of its devices: the questionnaire and the budget. This approach allowed to highlight the emergence of a form of activism carried by the mobilization of experts. The text concludes by interpreting the census as an informational infrastructure that inscribes, imagines and stabilizes ideals for the future through numbers
The missing link: an examination of skin clothing production of north central plains Native Americans
No full textDeer hides are one of the most commonly used materials for clothing production among the prehistoric Northern Great Plains peoples. Richard Michael Gramly?s 1977 article, Deerskins and Hunting Territories: Competition for a Scarce Resource of the Northeastern Woodlands, assumed an estimate of 3.5 hides per person per year. A figure widely cited in anthropological literature, yet provides no supporting data. This investigation seeks to find that data as applied to the Plains Indians. Measurements were taken of known clothing articles to determine surface area, and these were compared with the surface areas of average sizes of small, medium, and large hides. Comparing the surface areas allowed for an accurate estimation of the number of hides needed by both a man and woman for an appropriate climate wardrobe. Such information can be vital in interpreting prehistoric and historic hunting patterns, with significant social and ecological implications
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