335 research outputs found
The role of cardiovascular imaging for myocardial injury in hospitalized COVID-19 patients
No full textThis is a pre-copyedited, author-produced version of an article accepted for publication in European Heart Journal - Cardiovascular Imaging, following peer review. The version of record: Bernard Cosyns, Stijn Lochy, Maria Luiza Luchian, Alessia Gimelli, Gianluca Pontone, Sabine D Allard, Johan de Mey, Peter Rosseel, Marc Dweck, Steffen E Petersen, Thor Edvardsen, on behalf of the European Association of Cardiovascular Imaging (EACVI), The role of cardiovascular imaging for myocardial injury in hospitalized COVID-19 patients, European Heart Journal - Cardiovascular Imaging, Volume 21, Issue 7, July 2020, Pages 709–714, https://doi.org/10.1093/ehjci/jeaa136
is available online at: https://doi.org/10.1093/ehjci/jeaa13
A 46,X,inv(Y) young woman with gonadal dysgenesis and gonadoblastoma: cytogenetics, molecular, and methylation studies.
No full textA large analphoid invdup(3)(q22.3qter) marker chromosome characterized by array-CGH in a child with malformations, mental retardation, ambiguous genitalia and Blaschko's lines.
No full textDe novo Reciprocal Translocation t(5;6)(q13;q34) in Cattle: Cytogenetic and Molecular Characterization.
No full textThe cytogenetic analysis of a phenotypically normal bull from the Marchigiana breed revealed the presence of an abnormal karyotype due to the presence of a very long chromosome. This finding, identified in all the metaphases observed, was associated with the 2n = 60, XY karyotype, suggesting the presence of a reciprocal translocation. RBG- banding analyses identified a de novo reciprocal translocation involving BTA5 and BTA6, t(5;6)(q13;q34), while FISH analyses using cattle-specific BACs as probes enabled the confirmation and narrowed down the breakpoint regions. Array-CGH analysis also established that neither deletions nor duplications were present in the regions including the breakpoints, nor were they present elsewhere in the genome, confirming the balanced state of the translocation
Molecular cytogenetic characterization of the first reported case of an inv dup (4p)(p15.1-pter) with a concomitant 4q35.1-qter deletion and normal parents.
No full textArray-CGH analysis in a patient with WAGR syndrome and a reciprocal translocation t(2;11) inherited from the normal father with double translocation
No full textIdentification and molecular modelling of a novel familial mutation in the SRY gene implicated in the pure gonadal dysgenesis
No full text1D and 3D CFD Investigation of Burning Process and Knock Occurrence in a Gasoline or CNG fuelled Two-Stroke SI Engine
No full textThe paper presents a combined experimental and numerical investigation of a small unit displacement two-stroke SI engine operated with gasoline and Natural Gas (CNG). A detailed multi-cycle 3D-CFD analysis of the scavenging process is at first performed in order to accurately characterize the engine behavior in terms of scavenging patterns and efficiency. Detailed CFD analyses are used to accurately model the complex set of physical and chemical processes and to properly estimate the fluid-dynamic behavior of the engine, where boundary conditions are provided by a in-house developed 1D model of the whole engine. It is in fact widely recognized that for two-stroke crankcase scavenged, carbureted engines the scavenging patterns (fuel short-circuiting, residual gas distribution, pointwise lambda field, etc.) plays a fundamental role on both of engine performance and tailpipe emissions.In order to assess the accuracy of the adopted numerical approach, comparisons between numerical forecasts and experimental measurements of instantaneous in-cylinder pressure history for steady-state operations of the engine are at first performed and shown in the paper.Subsequently, results from 3D simulations are used to improve the scavenging characterization within the 1D model, where particular emphasis is now devoted to the investigation of the knock occurrence. In order to limit the computational cost of the simulations, the activity is at first carried out within the experimental and 1D modeling frameworks, where a quasi-dimensional combustion and knock model is used.The 1D model is used to compute a numerical knock index which can be useful to address the tuning of the spark advance, given a prescribed and controlled percentage of knock released heat. At the end of the simulation process, the 1D knock index is qualitatively compared to results from full 3D knocking analyses for different in-cylinder compositions and spark timings
Investigation of Scavenging, Combustion and Knock in a Two-Stroke SI Engine Operated with Gasoline and CNG
No full textThe paper reports a combined experimental and numerical investigation of a small unit displacement two-stroke SI engine operated with either Gasoline and Natural Gas (CNG).
It is widely recognized that for two-stroke, crankcase scavenged, carbureted engines the scavenging patterns (fuel short-circuiting, residual gas distribution, point wise lambda field, etc.) plays a fundamental role on both engine performance and tailpipe emissions. To properly characterize the engine behavior in terms of scavenging patterns and combustion, a detailed multi-cycle 3D-CFD analysis of the scavenging process is at first performed starting from preliminary 1D computed boundary conditions provided by a in-house developed 1D model of the whole engine.
In order to assess the accuracy of the adopted numerical approach, comparisons between numerical forecasts and experimental measurements of the instantaneous in-cylinder pressure history for steady-state operations of the engine are at first performed and shown in the paper. Subsequently, the activity is focused on the investigation of knock occurrence. In order to limit the computational cost of the simulations, calculations are at first carried out within the 1D modeling framework, where customized quasi-dimensional combustion and knock models are used. In particular, the 1D model is used to compute a numerical knock index which can be useful to address the tuning of the spark advance, given a prescribed and controlled percentage of knock released heat. At the end of the simulation process, the 1D knock index is qualitatively compared to results obtained from full 3D knocking analyses for different in-cylinder compositions and spark timings. The intrinsic knock-resistance of the CNG fuel is finally numerically exploited, through variations of both compression ratio and spark advance
A t(7;12) balanced translocation with breakpoints overlapping those of the Williams-Beuren and 12q14 microdeltion syndromes.
No full text- …
