285 research outputs found
Building capacity for sustainable product service systems in Australian industrial design education: a reflection upon contemporary practice
No full textProduct service systems (PSS) have broadened sustainability agendas within industrial design (ID) education in Australia. In building PSS capacities for ID practice the relationships between need and use (service) and the mediating nature of tangible products and their attunement to cultural and contextual conditions get amplified. This article reflects on our work in accentuating the nature of ID in PSS through education. We discuss how we have adapted the original notion of PSS; retaining its principles but taking new approaches in the design of products that are central to a service proposition. A series of case studies of PSS in ID education from members of the LeNS Oceania network are conveyed to illustrate systemic concerns of design in product and service making. The authors describe a variety of ways in which PSS innovations have been framed and might be furthered within the Australian ID education context
The beach-seine fishery off Durban, KwaZulu-Natal
No full textThe beach-seine fishery at Durban was investigated from July 1993 to June 1994. During this period the fishermen completed 270 hauls on 146 days of operation. In total, 119 species of fish as well as squid, cuttlefish and crabs were recorded in the catches. Most of these were small shoaling species belonging to the families Leiognathidae, Engraulidae and Clupeidae. Many species were caught at sizes below their reported size at first maturity. Based on this study and data from the National Marine Linefish System, there appears to be little overlap in the catches of the beach-seine netters and other fishery sectors in the area
New Prostate MRI Scoring Systems (PI-QUAL, PRECISE, PI-RR, and PI-FAB): AJR Expert Panel Narrative Review
No full textMultiparametric MRI (mpMRI), interpreted using PI-RADS, improves the initial detection of clinically significant
prostate cancer (PCa). Prostate MR image quality has increasingly recognized relevance to the use of mpMRI for
PCa diagnosis. Additionally, mpMRI is increasingly used in scenarios beyond initial detection, including active
surveillance and assessment for local recurrence after prostatectomy, radiation therapy, or focal therapy. Acknowl-
edging these evolving demands, specialized prostate MRI scoring systems beyond PI-RADS have emerged, to
address distinct scenarios and unmet needs. Examples include Prostate Imaging Quality (PI-QUAL) for assessment
of image quality of mpMRI, Prostate Cancer Radiologic Estimation of Change in Sequential Evaluation (PRECISE)
recommendations for evaluation of serial mpMRI examinations during active surveillance, Prostate Imaging for
Recurrence Reporting System (PI-RR) for assessment for local recurrence after prostatectomy or radiation therapy,
and Prostate Imaging after Focal Ablation (PI-FAB) for assessment for local recurrence after focal therapy. These
systems’ development and early uptake signal a compelling shift towards prostate MRI standardization in differ-
ent scenarios, and ongoing research will help refine their roles in practice. This AJR Expert Panel Narrative Review
critically examines these new prostate MRI scoring systems (PI-QUAL, PRECISE, PI-RR, and PI-FAB), analyzing the
available evidence, delineating current limitations, and proposing solutions for improvement
Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
No full textEuropean
Union Horizon 2020 Program under the Innovative Medicines Initiative
2 Joint Undertaking (grant agreement number 115916 (Project PRISM)
and grant agreement number 777394 (Project AIMS-2-TRIALS)),
Fundación Familia Alonso and Fundación Alicia Koplowitz. We
acknowledge the Biobanc of Parc Sanitari Sant Joan de Déu and
Centro de Investigación Biomédica en Red de Salud Mental for
samples and data procurement. J.G.-P. holds a Sara Borrell grant from
Instituto de Salud Carlos III (CD20/00118). B.R. has received support
from the Spanish Ministry of Science and Innovation Instituto de
Salud Carlos III (PI18/00213 and Miguel Servet grants CPII21/00008
and MS16/00153), cofinanced by European Regional Development Fund Funds from the European Commission (...)Liu D, Meyer D, Fennessy B, Feng C, Cheng E, Johnson JS, Park YJ, Rieder MK, Ascolillo S, de Pins A, Dobbyn A, Lebovitch D, Moya E, Nguyen TH, Wilkins L, Hassan A; Psychiatric Genomics Consortium Phase 3 Targeted Sequencing of Schizophrenia Study Team; Burdick KE, Buxbaum JD, Domenici E, Frangou S, Hartmann AM, Laurent-Levinson C, Malhotra D, Pato CN, Pato MT, Ressler K, Roussos P, Rujescu D, Arango C, Bertolino A, Blasi G, Bocchio-Chiavetto L, Campion D, Carr V, Fullerton JM, Gennarelli M, González-Peñas J, Levinson DF, Mowry B, Nimgaokar VL, Pergola G, Rampino A, Cervilla JA, Rivera M, Schwab SG, Wildenauer DB, Daly M, Neale B, Singh T, O'Donovan MC, Owen MJ, Walters JT, Ayub M, Malhotra AK, Lencz T, Sullivan PF, Sklar P, Stahl EA, Huckins LM, Charney A
Effect of copper supplementation on copper status of pregnant mares and foals
No full textPregnant Thoroughbred mares (n=21) were grazed on tall fescue pasture containing Cu 4.4-8.6 mg/kg DM. Twelve mares were supplemented daily with Cu 0.5 mg/kg liveweight (LW) as copper sulphate for the final 13-25 weeks of gestation. Plasma Cu declined during the third trimester for all mares and was not affected by Cu supplementation. Liver Cu concentration of mares and foals was estimated when foals were 4-10 days old. Cu supplementation of mares tended to increase mare liver Cu level and also foal liver Cu (P<0.01). There was a significant relationship between mare and foal liver Cu level (P<0.001, r² = 0.7). It is concluded that increasing the Cu intake of mares is effective in enhancing the Cu status of foals.ID: 699; Accession Number: 19981409815. Publication Type: Journal Article. Language: English. Number of References: 33 ref. Registry Number: 7440-50-8. Subject Subsets: Veterinary Science; Animal NutritionSource type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=lah&AN=19981409815&site=ehost-liv
Service Design Drinks Milan: a case of local community building around service design
No full textThis contribution aims at reporting a case of community building and activation in the city of Milan in Italy, namely the Service Design Drinks Milan.
The kind of community that we are referring to doesn't necessarily build upon the belonging to a specific territory, but rather on a common interest around a topic, which is the discipline of service design. The case described provides a source of inspiration for any local agent wanting to replicate a similar initiative in its own context or for anyone interested in exploring the communities of interest
Image quality of whole-body diffusion MR images comparing deep-learning accelerated and conventional sequences
No full textObjectives: To compare the image quality of deep learning accelerated whole-body (WB) with conventional diffusion sequences. Methods: Fifty consecutive patients with bone marrow cancer underwent WB-MRI. Two experts compared axial b900 s/mm2 and the corresponding maximum intensity projections (MIP) of deep resolve boost (DRB) accelerated diffusion-weighted imaging (DWI) sequences (time of acquisition: 6:42 min) against conventional sequences (time of acquisition: 14 min). Readers assessed paired images for noise, artefacts, signal fat suppression, and lesion conspicuity using Likert scales, also expressing their overall subjective preference. Signal-to-noise and contrast-to-noise ratios (SNR and CNR) and the apparent diffusion coefficient (ADC) values of normal tissues and cancer lesions were statistically compared. Results: Overall, radiologists preferred either axial DRB b900 and/or corresponding MIP images in almost 80% of the patients, particularly in patients with a high body-mass index (BMI > 25 kg/m2). In qualitative assessments, axial DRB images were preferred (preferred/strongly preferred) in 56-100% of cases, whereas DRB MIP images were favoured in 52-96% of cases. DRB-SNR/CNR was higher in all normal tissues (p < 0.05). For cancer lesions, the DRB-SNR was higher (p < 0.001), but the CNR was not different. DRB-ADC values were significantly higher for the brain and psoas muscles, but not for cancer lesions (mean difference: + 53 μm2/s). Inter-class correlation coefficient analysis showed good to excellent agreement (95% CI 0.75-0.93). Conclusion: DRB sequences produce higher-quality axial DWI, resulting in improved MIPs and significantly reduced acquisition times. However, differences in the ADC values of normal tissues need to be considered. Clinical relevance statement: Deep learning accelerated diffusion sequences produce high-quality axial images and MIP at reduced acquisition times. This advancement could enable the increased adoption of Whole Body-MRI for the evaluation of patients with bone marrow cancer. Key points: Deep learning reconstruction enables a more than 50% reduction in acquisition time for WB diffusion sequences. DRB images were preferred by radiologists in almost 80% of cases due to fewer artefacts, improved background signal suppression, higher signal-to-noise ratio, and increased lesion conspicuity in patients with higher body mass index. Cancer lesion diffusivity from DRB images was not different from conventional sequences
The effect of copper supplementation on copper status of pregnant mares and their neonates
No full textSource type: Print(0
Wetland ecological character and wise use: Towards a new framing
No full textEcological character and wise use are central tenets underpinning the Ramsar Convention's global wetland ambitions. In this paper, we postulate that, given on-going and progressive degradation and destruction of wetlands, these concepts require reframing. So as to overcome the human-nature dualism, which underpins current wetland conservation, we propose that wetlands need to be placed within a social-ecological framing that can accommodate a plurality of worldviews and value systems. This reframing broadens the definition of wetland ecological character and replaces it with a more inclusive and comprehensive term 'wetland character'. Wise use, consequently, becomes maintenance of wetland character. Further considerations on maintaining wetland character under this construct are presented.No Full Tex
Determining nature’s contributions to achieve the sustainable development goals
No full textAcademics and policy-makers recognize that humans and nature should be studied and managed as integrated social?eco-logical systems. Recently, the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) approved the Summary for Policy-makers of the Regional and Subregional Assessment of Biodiversity and Ecosystem Services for the Americas, concluding the environment should be mainstreamed across development sectors. Beyond its mandate to generate understanding of nature and human well-being from diverse knowledge sources, IPBES is also tasked with advancing science-policy tools to aide information uptake into decisions. Based on the Americas Assessment?s 3-year, continental-scale experience, we developed three strategies to guide decisions regarding nature?s contributions to people (NCP) for achieving the sustainable development goals (SDGs). Specifically, we prioritized contributions, recognized nature?s plural values, and grouped diverse human?nature relationships to orient attention towards important NCP?SDG linkages, expand the suite of environment?development criteria considered, and create bundles to facilitate the incorporation of complexity into decisions.Fil: Anderson, Christopher Brian. Universidad Nacional de Tierra del Fuego; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; ArgentinaFil: Seixas, Cristiana S.. Universidade Estadual de Campinas; BrasilFil: Barbosa, Olga. Universidad Austral de Chile; Chile. Instituto de Ecología and Biodiversidad; ChileFil: Fennessy, M. Siobhan. Kenyon College; Estados UnidosFil: Díaz José, Julio. Universidad Veracruzana; México. Tecnologico Nacional de Mexico; MéxicoFil: Bernal Herrera, F.. Fundación para el Desarrollo de la Cordillera Volcánica Central; Costa Rica. Universidad Nacional de Costa Rica; Costa Ric
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