428 research outputs found
Liver-limited resectable stage IV: current reality and future perspectives
With refinements in patient selection criteria and surgical techniques, as well as with implementation of a multimodal approach, liver resection permits to obtain 5-year overall survival rates of 50–58%. Improvements in long-term survival have been obtained despite a dramatic change in the definition of resectability to include a number of patients once deemed unresectable. Contemporary criteria used to define resectability are simple. Liver metastases are defined as resectable if: all lesions can be technically resected, with a negative margin, leaving an adequate liver remnant. High-quality imaging is essential to determine resectability. MRI with liver-specific contrast agents should routinely be considered in patients with multiple or small lesion and to restage patients after chemotherapy. Response to chemotherapy is emerging as one of the most powerful prognostic factors. Hepatobiliary surgeons and medical oncologists should work together to evaluate patients with colorectal liver metastases to individualize treatment strategies and maximize the chances of long-term survival
Data for: Trade-off between the economic and ecological impact of different decarbonisation strategies for residential buildings
“E3 - A parametric model to evaluate trade-offs between the Energetic, Economic, and Environmental lifecycle performance of building projects” is a spreadsheet tool for the calculation of the environmental and economic lifecycle impact, as well as the Pareto optimal evaluation method, of strategies for residential buildings. Quantities of the building´s components (building geometry, materials or assembly types and their sizes, number of flats, number of tenants, and so on) are retrieved from technical plans. Calculation of quantities is performed according to the definitions described in DIN 277-1. Quantities and parameters for the building services components are determined by balancing all energy load (demand) profiles with energy generation profiles. Energy profiles are modelled in the E3 tool on an hourly basis (that is, using 8,790 points) for a typical year of operation. Energy load profiles determine the peak load for building services, which is used to determine each component´s required size. For photovoltaic cells and solar thermal collectors, peak load and size are constrained by the available surface. All other components can be modularly scaled to any size. Finally, energy generation profiles are used to determine primary energy use for building operation. Energy load profiles include heating energy demand, warm water demand, user power demand, and auxiliary power demand. Heating energy demand is calculated by assessing the thermal quality of the building envelope as a factor of temperature (W/K) over time (h). The thermal quality of the building envelope is found by balancing transmission losses through the building envelope and ventilation losses against solar thermal energy gains and internal heat gains. Energy generation profiles are modelled using factors to represent the efficiency of transforming a primary energy source (photons, solar thermal energy, gas, or grid power) in delivered energy (thermal energy or electricity)
PalMuc/CalciteSea: archive for Zenodo
<p>Archive of data supplementary to</p><p>Conci N., Griesshaber E., Rivera-Vicéns R., Schmahl W., Vargas S. and Wӧrheide G (2022) Molecular and mineral responses of corals grown under artificial Calcite Sea conditions. bioRxiv 2022.02.25.481970 DOI:<a href="https://doi.org/10.1101/2022.02.25.481970">https://doi.org/10.1101/2022.02.25.481970</a></p>
Selective inflorescence thinning as a tool to improve yield quality of everbearing strawberry
The use of programmed plants of everbearing strawberry is based on the idea of a conspicuous first flush yield, thus inflorescence and flower number are fundamental. Everbearing-programmed plants are often variable in terms of crown number and, frequently, some inflorescences are weak and show an advanced phenological stage. The aim of the trial was to determine the influence of selective inflorescence thinning on yield of plants grown on three growing media. On April 14, 2014, 'Capri' strawberry A+ plants were transplanted in 3 different growing media: 85% peat and 15% coir (PC), 50% coir and 50% conifer wood (CW) and 100% coir (CC). On May 6, all the inflorescences with a short and thin stalk, a basal branching habit and at the phenological stage 'early balloon' (58 BBCH scale) or later were removed. Despite an average pruning of about one out of three trusses each plant, there was no significant difference in the marketable yield. First flush beginning was delayed, but was over at the same time, anyway, the total value remained almost the same thanks to the significant increase in the fruit weight. The inflorescence thinning allowed eliminating the flowers that would have generated small or misshapen fruits. There were no effects on the other part of the harvest curve. Growing media influenced the marketable yield, however, only on CW, the treatment that had the lowest production, the thinning determined a higher yield, suggesting that the initial lack of fruits permitted a more equilibrate plant development in a substrate that usually decreases plant vigour. The selective thinning showed to be a useful technique, which allowed to increase the yield qualit
Head dorsal pancreatectomy: an alternative to the pancreaticoduodenectomy for not enucleable benign or low-grade malignant lesions.
Head dorsal pancreatectomy (HDP) is a segmental pancreatic resection, conservative variant of total dorsal pancreatectomy, applied to preserve the functional pancreatic parenchyma as an alternative to pancreaticoduodenectomy in not enucleable benign or low-grade malignant lesions. The absences of biliary and gastrointestinal resection/reconstruction are the other advantages of the technique.
METHODS:
We reported a case of HDP performed in a female 39-year-old patient for a neuroendocrine tumour of the dorsal portion of the pancreatic head.
RESULTS:
The superior mesenteric vein was dissected from the pancreatic neck. The pancreas was transected at the left margin of the superior mesenteric vein. After identification and mobilisation of gastroduodenal artery and the anterior superior pancreatico-duodenal artery, the head dorsal segment was dissected stepwise from the duodenal wall toward the common bile duct plane; the dissection of the pancreatic parenchyma was completed along the anterior surface of the common bile duct. An end-to-side duct-to-mucosa pancreaticojejunostomy was performed. The main pancreatic duct in the ventral segment on the dissection parenchymal surface was ligated. With the inclusion of this case, there are a total of 3 cases involving resection of the dorsal portion of the pancreatic head reported in the literature.
CONCLUSION:
HDP seems to be technically feasible and safe for not enucleable benign or low-grade malignant neoplasms involving the dorsal pancreatic head. However, due to the singularity of the indications and the few cases reported in the literature, further studies are needed to validate the technique
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