52 research outputs found
Dental pain threshold and angina pectoris in patients with coronary artery disease
No full textAbstractOne hundred eight consecutive patients with proved coronary artery disease and reproducible exercise-induced myocardial ischemia were studied. During repeated exercise testing, 52 patients (Group I) had myocardial ischemia in the absence of pain (silent ischemia) whereas 56 patients (Group II) experienced anginal symptoms in the presence of electrocardiographic signs of ischemia. A puipal test was carried out in all patients using an electrical dental stimulator commonly used in dentistry. Electrical current was delivered in increasing intensity from 10 to 500 mA, and the dental pain threshold and the reaction of the patients to maximal stimulation were determined.During the puipal test, 71.2% of the patients in Group I did not experience pain, even at maximal stimulation (threshold 0), 11.5% were sensitive at threshold I (10 to 200 mA) and 17.3% felt pain at threshold II (210 to 500 mA). In Group 11, 69.7% of the patients complained of dental pain at the low intensity test current (threshold I), 10.7% at threshold II and 19.6% at threshold 0. In Group I, 71.2% of patients did not have discomfort (reaction −), even at maximal stimulation, 21.1% had a mild reaction (reaction +) and 7.7% had an intense painful reaction (reaction ++). In Group II, 80.4% of patients were sensitive to the pulpar test (67.9% reported intense painful sensation at maximal stimulation, 12.5% had a mild reaction); 19.6% of patients had no reaction.The two groups of patients were similar with respect to age, sex and angiographic features. Patients in Group I (silent ischemia) achieved a significantly longer duration of exercise (p < 0.01) in the presence of more pronounced ST segment depression (p < 0.001) and had a higher rate-pressure product at peak exercise (p < 0.01).The significant difference in dental pain threshold (p < 0.0005) and reaction (p < 0.0005) in patients with and those without anginal symptoms during exercise testing suggests that a generalized, nonsegmental hyposensitivity to pain may partly explain the lack of symptoms in patients with silent myocardial ischemia
Beta endorphin plasma levels in patients with and without anginal pain during myocardial ischemia
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Correlation between Beta endorphin blood levels and anginal pain in patients with coronary artery diasease
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Correlation between beta-endorphin plasma levels and anginal symptoms in patients with coronary artery disease
No full textAbstractTo verify whether beta-endorphin plasma levels influence the presence of anginal symptoms. 74 consecutive male patients were studied. All patients had previously documented coronary artery disease and reproducible exerciseinduced myocardial ischemia. Thirty-five patients (Group I) had a history of angina and reported anginal symptoms during exercise stress testing; 39 patients (Group II) were asymptomatic and had documented silent myocardial ischemia during exercise. Baseline beta-endorphin plasma levels were measured in blood ramples taken before exercise stress testing and analyzed by beta-endorphin-I125-RIA Kit-NEN (a radioimmunoassay method).The mean baseline beta-eadorphin plasma level was 22.5 ± 19 pg/ml in patients with anginal symptoms compared with 43.7 ± 28 pg/ml in asymptomatic patients (p < 0.001). Baseline blood pressure and heart rate-systolic pressure (rate-pressure) product at baseline and at ischemia threshold (1 mm ST segment depression) were similar in the two groups, Group II patients had a longer exercise duration p < 0.01), more pronounced ST segment depression (p < 0.001) and a higher peak rate-pressure product (p < 0.01). The extent of coronary artery disease, ejection fraction and left ventricular end-diastolic pressure were similar in the two groups.These data suggest that higher baseline bata-endorphin plasma levels may play a role in the decreased sensitevity to pain in patients with slient myocardial ischemia. In addition, different beta-endorphin levels can be associated with a different sensitivity to pain
Aritmie ventricolari durante test di master in giovani atleti: incidenza aritmica rispetto al test ergometrico
No full textStudio della resistenza ad aminoglicosidi e penicillina in Enterococchi di isolamento clinico
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