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Mobile intelligence for reporting of supply chain KPI's
No full textA Supply Chain Manager is in the departure lounge at Munich airport waiting for her flight
to London to discuss size curves of the latest range of sports shoes with the Retail
Manager of the company’s flagship London retail store. The SC Manager opens up an
application on her smartphone that displays the stock levels for the season’s top selling
shoes. She immediately sees that the stock turnover for this range is much higher at the
London store than at other leading stores across Europe. The London Retail Manager
wants to change the range profile to better reflect UK customer sizes and tastes. The
SCM Manager has a printed version of last year’s size curves (showing how many of each
size were shipped and sold to the UK), however, she would like to see what the latest
figures are for this quarter. She simply opens the size curve application on her
smartphone and calls up the figures she needs.
This kind of scenario is increasingly being played out by executives and managers (many
of whom spend very little time in the office) as they travel to meetings remote from their
colleagues and the company intranet. It is fair to say that in many cases, retrieval of the
information that is required is not as easy as the above situation implies. There are many
reasons for this including restrictions on data sharing/retrieval, scattering of data across
formats/ databases and insufficient specification by the managers of their requirements.
Mobile intelligence systems utilise devices such as mobile phones and tablet computers
(smartphones, iPad, Playbook, etc.) as handheld workstations for users to access and
analyse real time information. Essentially they allow managers to access performance
information quickly and in an easy to communicate visual way (e.g. bar charts, pie charts
etc. see for example Figure 1). Mobile intelligence in a supply chain management
reporting context allows users to access supply chain-related information anywhere and
make quick, informed decisions. Supply chain specific examples include delivery
performance tracking and alerts for low inventory levels. Mobile phone applications
(‘Apps’) can now offer managers more opportunities to connect and share information
than, for example, a laptop due to the level of connectivity and network coverage around
the world
An excerpt from Urmila Pawar\u27s Autobiography
Get PDFThe term "Dalit literature" is used to describe works written by authors from the Dalit ethnic minority. The hardships and triumphs of the Dalit people were mirrored in this body of writing. It also revealed their uphill battle in life to the outside world. They are victims of centuries of discrimination and oppression at the hands of those in power in their own nation. Social transformation in this society owes a great deal to the efforts of notable individuals like B.R. Ambedkar. Dalit writings have emphasized the rights and agency of the Dalit community. Many authors of Dalit descent have written on the difficulties inherent in their language and culture. They questioned the privilege of the higher caste and advocated for the adoption of vernacular speech. Several Dalit authors have achieved widespread acclaim for their works. There are several famous authors from India, like Bama (K.R. Meera), Om Prakash Valmiki, Chetan Divate, Urmila Pawar, and Daya Pawar. Urmila Pawar is a well-known Marathi author and activist. She has achieved widespread renown as a writer due to the autobiographical nature of her books. Her works are impacted by both her time as a student and her time as an educator.
 
Scanning electron microscopy analysis of the intratubular radicular dentin penetration of calcium hydroxide, triple antibiotic paste, and nitrofurantoin
Get PDFThe aim of this study is to assess and analyze the intratubular penetration of the intracanal medications nitrofurantoin (Nit), triple antibiotic paste (TAP), and calcium hydroxide (CH). Sixty freshly extracted single-rooted teeth were acquired and decoronated to a standard length of 15 mm. To prepare specimens up to size F3, rotary ProTaper instrumentation was employed. The prepared teeth were divided into three groups, each of which received one of the tested intracanal medicaments: Group I (calcium hydroxide), Group II (triple antibiotic paste), and Group III (nitrofurantoin). Using a size #30 Lentulo spiral, a freshly prepared therapeutic paste was placed into the canals, and the intracanal medicaments were allowed to set in the incubator at 100% humidity. The samples were subsequently sliced perpendicularly to their long axis using a precision saw and assessed under a scanning electron microscope to assess the depth of penetration of intracanal medicaments at the coronal, middle, and apical portions of the root canal dentin. The data were analyzed using one-way ANOVA and Tukey’s post hoc test. The statistical analysis revealed a significant difference between the experimental groups in the quantity and depth of sealer penetration (p < 0.05). In particular, as compared to the Nit group, both the CH and TAP groups had significantly smaller penetration areas (p < 0.05). In conclusion, this ongoing investigation indicates that nitrofurantoin penetrated dentinal tubules better than calcium hydroxide or triple antibiotic paste
Glucose and serum deprivation led to altered proliferation, differentiation potential and AMPK activation in stem cells from human deciduous tooth
Get PDFStem cell therapy is an evolving treatment strategy in regenerative medicine. Recent studies report stem cells from human exfoliated deciduous teeth could complement the traditional mes-enchymal stem cell sources. Stem cells from human exfoliated deciduous teeth exhibit mesenchymal characteristics with multilineage differentiation potential. Mesenchymal stem cells are widely investigated for cell therapy and disease modeling. Although many research are being conducted to address the challenges of mesenchymal stem cell therapy in clinics, most of the studies are still in infancy. Host cell microenvironment is one of the major factors affecting the homing of transplanted stem cell and understanding the factors affecting the fate of stem cells of prime important. In this study we aimed to understand the effects of serum deprivation in stem cells derived from human deciduous tooth. Our study aimed to understand the morphological, transcriptional, cell cycle and stemness based changes of stem cells in nutrient deprived medium. Our results suggest that stem cells in nutrient deprived media undergo low proliferation, high apoptosis and changed the differentiation potential of the stem cells. Serum deprived mesenchymal stem cells exhibited enhanced chondrogenic differentiation potential and reduced osteogenic differentiation potential. Moreover, the activation of key metabolic sensor AMP-activated kinase (AMPK) leads to activation of transcription factors such as FOXO3, which leads to an S phase quiescence. Serum deprivation also enhanced the expression of stemness related genes Sox2 and c-Myc
Anesthetic Management for Pulmonary Thromboendarterectomy
No full textPawar, S., Alshoubi, A., Ginsburg, E. (2021). Anesthetic Management for Pulmonary Thromboendarterectomy. In: Awad, MD, MBA, A.S. (eds) Cardiac Anesthesia. Springer, Cham. https://doi.org/10.1007/978-3-030-51755-7_2
RNA-seq and miRNA-seq data from pharmacological inhibition of the G9a/GLP histone methyltransferase complex with UNC0642
No full textGrowing evidence demonstrates the epigenetic modulation as a key event in Alzheimer’s disease (AD) pathology. Furthermore, recent data suggests that the epigenetic regulation by the methyltransferase G9a is a crucial mechanism involved in learning and memory formation. Taking this into account, the present study provides genomics data from pharmacological intervention with UNC0642, a potent and selective G9a/GLP in SAMP8 mice, a model of Alzheimer’s disease (AD). We have generated novel RNA-seq and miRNA-seq data for three groups, healthy SAMR1, SAMP8 control and SAMP8 treated with UNC0642 (5mg/Kg). Thus, the new data can be used to find miRNA regulation, and the mRNA’s modified in AD under G9a/GLP inhibition
RNA-seq and miRNA-seq data from pharmacological inhibition of the G9a/GLP histone methyltransferase complex with UNC0642 in SAMP8 mice
No full textGrowing evidence demonstrates the epigenetic modulation as a key event in Alzheimer’s disease (AD) pathology. Furthermore, recent data suggests that the epigenetic regulation by the methyltransferase G9a is a crucial mechanism involved in learning and memory formation. Taking this into account, the present study provides genomics data from pharmacological intervention with UNC0642, a potent and selective G9a/GLP in SAMP8 mice, a model of Alzheimer’s disease (AD). We have generated novel RNA-seq and miRNA-seq data for three groups, healthy SAMR1, SAMP8 control and SAMP8 treated with UNC0642 (5mg/Kg). Thus, the new data can be used to find miRNA regulation, and the mRNA’s modified in AD under G9a/GLP inhibition
Room temperature operable ultra-sensitive ammonia sensor based on polyaniline-silver (PANI-Ag) nanocomposites synthesized by ultra-sonication
No full textThis paper reports a novel, highly sensitive room temperature operable and reusable ammonia (NH3) gas sensor based on Polyaniline-silver nanocomposite (PANI-Ag). The nanocomposite was synthesized by in-situ, sono-chemical oxidative polymerization methods by using ammonium persulphate. Aniline was used as a dispersant and stabilizer, D-glucose was chosen as an efficient reducing agent for the formation of Ag nanoparticles in the sol. The structural and optical properties of PANI-Ag nanocomposite were studied by FTIR spectroscopy, X-ray diffraction (XRD) and scanning electron microscopy (SEM). Morphological analysis of PANI-Ag nanocomposites revealed a cluster of PANI nanofibers with uniformly distributed silver nanoparticles having an average particle size of about 6 nm. The performance of PANI-Ag based sensor was evaluated at different concentrations of aqueous ammonia at room temperature. The sensor is highly sensitive at low ammonia concentration (less than 100 ppm). The sensor showed fast response and recovery time in the range of 30-120 s from 1 ppm to 100 ppm of ammonia concentration. The sensor showed an optimum response of 57% for 100 ppm ammonia. Due to excellent reversibility, reusability and long term environmental stability, PANI-Ag sensor provides a promising simple and efficient sensor system for wide-range ammonia concentration detection at room temperature
Nationwide trends of modern endodontic practices related to working length, instrumentation, magnification, and obturation: a comparative cross-sectional survey comparing endodontic and non-endodontic specialties practicing root canal treatment in India
Get PDFAim: The present study was designed to assess trends in contemporary endodontic practice regarding the techniques and materials used in endodontic therapy among dental practitioners from various regions of India. Methods: A cross-sectional questionnaire-based study was conducted amongst dentists who were pursuing postgraduates in endodontics (PG Endo) and other branches (PG-OB), specialists from other branches (MDS-OB) and specialists in endodontics (MDS-Endo) in various dental colleges representing East, West, North, South, and Central zones through an e-survey using Google forms. State-wise postgraduate dental college lists were obtained from the Dental Council of India (DCI) website. Using a multistage cluster random sampling method and considering the unanticipated response rate, emails were sent to 2100. A 29-item close-ended questionnaire, framed according to different aspects of endodontic treatment, was used to record the responses. Results: When the distribution of the groups of dentists was compared, the central zone had the highest number of PG-OB (44.2%) and the lowest number of MDS-Endo (8.4%). The electronic apex locator (EAL) method of working length determination has been reported less among MDS-Endo than MDS-OB. The difference between the usage of various methods for working length determination was significant among the different groups in all the zones. (p < 0.0001) Most MDS-Endo preferred the rotary method of instrumentation over the combination method for different zones. The majority of dental practitioners preferred a combination method of instrumentation. Conclusion: Zone-wise comparisons among dentists showed the majority of general dental practitioners preferred the combination method (radiographs and electronic apex locator) for working length determination. Most MDS-Endo preferred the rotary method of instrumentation over the combination method for different zones. All dental practitioners did not so commonly use magnification in all the zones. The single cone technique was the most opted by dental practitioners of all the zones
Set Membership with Two Classical and Quantum Bit Probes
Get PDFWe study the classical and quantum bit-probe versions of the static set membership problem : Given a subset, S (|S| ≤ n) of a universe, (|| = m ≫ n), represent it as a binary string in memory so that the query "Is x in S?" (x ∈ ) can be answered by making at most t probes into the string. Let s_{A}(m,n,t) denote the minimum length of the bit string in any scheme that solves this static set membership problem. We show that for n ≥ 4
s_A(m,n,t = 2) =
(m^{1-1/(n-1)}) (if n = 0 (mod 3));
(m^{1-1/n}) (if n = 1,2 (mod 3));
(m^{6/7}) (if n = 8,9).
These bounds are shown using a common scheme that is based on a graph-theoretic observation on orienting the edges of a graph of high girth. For all n ≥ 4, these bounds substantially improve on the previous best bounds known for this problem, some of which required elaborate constructions [Mirza Galib Anwarul Husain Baig and Deepanjan Kesh, 2020]. Our schemes are explicit. A lower bound of the form s_A(m,n,2) = Ω(m^{1-1/⌊{n/4}⌋}) was known for this problem. We show an improved lower bound of s_A(m,n,2) = Ω(m^{1-2/(n+3)}); this bound was previously known only for n = 3,5 [Mirza Galib Anwarul Husain Baig and Deepanjan Kesh, 2020; Mirza Galib Anwarul Husain Baig et al., 2019; Mirza Galib Anwarul Husain Baig and Deepanjan Kesh, 2018; Mirza Galib Anwarul Husain Baig et al., 2019; Mirza Galib Anwarul Husain Baig and Deepanjan Kesh, 2020].
We consider the quantum version of the problem, where access to the bit-string b ∈ {0,1}^s is provided in the form of a quantum oracle that performs the transformation _b: |i⟩ ↦ (-1)^{b_i} |i⟩. Let s_Q(m,n,2) denote the minimum length of the bit string that solves the above set membership problem in the quantum model (with adaptive queries but no error). We show that for all n ≤ m^{1/8}, we have s_{QA}(m,n,2) = (m^{7/8}). This upper bound makes crucial use of Nash-William’s theorem [Diestel, 2005] for decomposing a graph into forests. This result is significant because, prior to this work, it was not known if quantum schemes yield any advantage over classical schemes. We also consider schemes that make a small number of quantum non-adaptive probes. In particular, we show that the space required in this case, s_{QN}(m,n = 2,t = 2) = O(√m) and s_{QN}(m,n = 2,t = 3) = O(m^{1/3}); in contrast, it is known that two non-adaptive classical probes yield no savings. Our quantum schemes are simple and use only the fact that the XOR of two bits of memory can be computed using just one quantum query to the oracle
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