781 research outputs found
Importance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In Vivo
No full textCitation: Girinathan, B. P., Braun, S., Sirigireddy, A. R., Lopez, J. E., & Govind, R. (2016). Importance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In Vivo. Plos One, 11(7), 18. doi:10.1371/journal.pone.0160107Clostridium difficile is the principal cause of antibiotic-associated diarrhea. Major metabolic requirements for colonization and expansion of C. difficile after microbiota disturbance have not been fully determined. In this study, we show that glutamate utilization is important for C. difficile to establish itself in the animal gut. When the gluD gene, which codes for glutamate dehydrogenase (GDH), was disrupted, the mutant C. difficile was unable to colonize and cause disease in a hamster model. Further, from the complementation experiment it appears that extracellular GDH may be playing a role in promoting C. difficile colonization and disease progression. Quantification of free amino acids in the hamster gut during C. difficile infection showed that glutamate is among preferred amino acids utilized by C. difficile during its expansion. This study provides evidence of the importance of glutamate metabolism for C. difficile pathogenesis
Two-fluid Physical Modeling of Superconducting Resonators in the ARTEMIS Framework
No full textInput files, data files and scripts to replicate results in "Two-fluid Physical Modeling of Superconducting Resonators in the ARTEMIS Framework" (Jambunathan et el.)
Please direct any questions to the corresponding author, Revathi Jambunathan (rjambunathan [at] lbl.gov)
Artemis simulations were run using the development branch of artemis https://github.com/ECP-WarpX/artemis
Some simulations in this paper were performed with different commit hashes of artemis and amrex, however, the input files should still work with the most recent development branch of artemis.
In the attached tar file, the input files, data, and scripts used to analyse simulation results shown in Figures 1, 2, 3, 4, and 6 of the paper are provided. To run the simulations on perlmutter GPUs, the code is compiled with USE_GPU=TRUE and USE_LLG=FALS
Cloud-Assisted Privacy-Preserving Method for Healthcare Using Adaptive Fractional Brain Storm Integrated Whale Optimization Algorithm
No full textFamilial relationship and its impact on the psyche of transgenders: A study of The Truth About Me by Revathi
No full textModern society is evolving each day, technologically, socially, and economically. Nevertheless, society marginalizes people based on their gender, caste, sex, etc., and transgenders stand on the gruesome end of this line. Even though transgenders have become part of the active phase of contemporary society, they are often segregated by the name ‘transgender.’ Gender identity is always a major issue in the thick and thin of society. They are also termed as people of the third gender. Still, people believe that transgenders are sex workers or they were born cursed. So, they disappear from the active phase of society. The public’s attitude toward transgenders is like untouchables and they taunt them without any humanity, putting them to the status of animals living in the streets. They earn a livelihood through sex work and begging. This is portrayed by Revathi in her autobiography, The Truth About Me: A Hijra Life Story. The paper attempts an analysis of how family plays a significant role in their acceptance in society. Almost all of them face issues emanating from the childhood traumas they experience. 
Factors associated with prehospital delay in patients with acute stroke in South India
No full textBackground: Early hospital presentation is critical in the management of acute ischemic stroke. The effectiveness of stroke treatment is highly dependent on the amount of time lapsed between onset of symptoms and treatment. This study was aimed to identify the factors associated with prehospital delay in patients with acute stroke. Material and Methods: A cross-sectional descriptive study was conducted in Sri Ramachandra University Hospital, India. A total of 210 patients hospitalized in the stroke unit were included. Patients' data were obtained by interviewing the patient and/or accompanying family member and by reviewing their medical records using a standard questionnaire. Associations were determined between prehospital delay (≥4.5 h) and variables of interest by using univariate and multivariate logistic regression analyses. Results: The prehospital delay was observed in 154 patients (73.3%) and the median prehospital delay was 11.30 h. The following are the factors significantly (P < 0.05) attributed for the delay in presenting to the hospital: contextual factors like using public transport (bus), taxi, time of onset of symptoms, 7 pm–3 am; family history of stroke, perceived cognitive and behavioral factors like, wishing or praying for the symptoms to subside on its own, hesitation to travel due to long distance, delay in arranging transport, and arranging money for admission and wasting time by shopping for general practitioners, nursing homes, and hospitals. The presence of stroke symptom, headache, significantly decreased the prehospital delay. Conclusions: Prehospital delay is high in South India and influenced by clinical, contextual, and cognitive/behavioral factors
Studies on Anti-lithogenic Potential Fenugreek Seeds
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Emerg Infect Dis
No full textWe report the emergence in Kenya during 1997-1999 of typhoid fever due to Salmonella enterica serovar Typhi resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, and cotrimoxazole. Genotyping by pulsed-field gel electrophoresis of XbaI-digested chromosomal DNA yielded a single cluster. The multidrug-resistant S. Typhi were related to earlier drug- susceptible isolates but were unrelated to multidrug-resistant isolates from Asia
Disruptive Technology: Do Robots Want Your Job?
No full textKeynote talk with Martin Ford, author of Rise of the Robots. Part of the “Deep Humanities,” One-Day Symposium: FrankenSTEM? Technology Ethics in Silicon Valley, organized by Dr. Revathi Krishnaswamy & Dr. Katherine D. Harris, Department of English and Comparative Literature, San Jose State University.
May 1, 2018, 7pm, The Tech Museum of Innovation, San Jose.https://scholarworks.sjsu.edu/frankenstein200_flyers/1003/thumbnail.jp
Hijra’s Customs As Elucidated In A.Revathi’s The Truth About Me
No full text This article entitled “Hijra’s Customs As Elucidated In A.Revathi’s‘The Truth About Me’””attempts to highlight the habitual practises (customs) of the hijra community.
Hijra is a term, used to refer a person whose birth sex is male but later identified to be female (trans-women). They usually live in well-defined and organised communities led by a guru. The author, A.Revathi is a Bengaluru-based, trans-woman, writer and activist whose debut book was in Tamil, Unarvum Uruvamum (2004). Following this, Revathi decided to write her own experiences and published her second book, The Truth about Me: A Hijra Life Story (2010). This book is a courageous and touching autobiography of a hijra where the author records the customs of their hijra community, giving special attention to the post-nirvaanam customs strictly practised for 40 days after castration.  
Have the Emerging Developing Economies been Enjoying the Inclusive Global Growth in the Export of Modern Services?
No full textDrawing on the definition of ‘inclusive growth’ of providing equitable opportunities for economic participants during economic growth, an important question that is investigated in this study is how inclusive is the export of modern services of computer and information services, and miscellaneous professional services in the international trade arena. Applying the yardstick of gauging the gap between potential and actual performances, the strength of ‘inclusive growth’ is measured. Using a meta-frontier framework, this paper compares the modern services export potential and meta-technology ratios for the selected high performing emerging economies of South and East Asia with the developed world. The results show that there are significant differences in the meta-technology ratios of the emerging countries in modern services compared to developed countries. Alarmingly, there is substantial unrealized export potential for high performing developing countries with respect to the benchmark frontier available to all countries implying lack of ‘inclusive growth’ in the international trade arena
- …
