58 research outputs found
A Guide to Instrumentalism: Initial Teacher Education in the Lifelong Learning Sector
No full textThis paper provides a critique of the competence based approach to teacher education in the Learning and Skills Sector. This critique is made at a time of consultation of proposed developments to the current standards, which are due for implementation from 2012 and which will involve only minor changes. The existing, Lifelong Learning UK (LLUK) standards were introduced in September 2006 following withdrawal of the old FENTO standards (FENTO, 1999) which had been subject to criticism that they did not meet the needs of trainee teachers and did not adequately reflect the developmental nature of Initial Teacher Education (ITE). The revised standards were intended to reflect this developmental process, and to contribute raising standards and the ‘professionalisation’ of the sector (DfES/Standards Unit 2004); however, even before their introduction concerns were raised about over-regulation (Lucas, 2004:49).
Despite a significant level of investment in the new standards, what eventually emerged has been subject to even greater criticism than the FENTO standards (e.g. see Lucas, 2007; Finlay et al 2007; Gleeson and James, 2007 and Simmons and Thompson 2007). Key features in this criticism have been the narrow concept of learning and skills, and the lack of recognition of both the wider dimensions of professional practice and the importance of knowledge. Contextualised within this literature, this paper argues that the detailed and prescriptive competency based structure of contemporary teacher training in the FE sector, together with wider regulation such as Ofsted and LLUK endorsement requirements, is productive of teachers who are instrumental and conformist but who lack the knowledge to engage with the concerns for social justice which are fundamental to working in the FE sector. In turn, these teachers deliver an instrumental and competency based vocational curriculum which, the paper argues, is complicit with other systems and structures in education in the reproduction of labour and of social class.
The paper also draws on literature addressing issues around assessment (Ecclestone, 2010) and professionalism (e.g. Gleeson and James, 2007; Bathmaker, 2006) as well as class based critiques of the FE system which draw on work by, amongst others, Avis, (2007), Atkins (2009) and Colley (2006). The arguments in this paper are also supported by a deconstruction of the current standards. This deconstruction has been used to identify what is – and is not – supported or promoted by the standards in the context of education and wider notions of professionalism and to problematise them in the context of contemporary literature
A Guide to Instrumentalism: Initial teacher education in the lifelong learning sector
No full textThis paper provides a critique of the competence based approach to teacher education in the Learning and Skills Sector. This critique is made at a time of consultation of proposed developments to the current standards, which are due for implementation from 2012 and which will involve only minor changes. The existing, Lifelong Learning UK (LLUK) standards were introduced in September 2006 following withdrawal of the old FENTO standards (FENTO, 1999) which had been subject to criticism that they did not meet the needs of trainee teachers and did not adequately reflect the developmental nature of Initial Teacher Education (ITE). The revised standards were intended to reflect this developmental process, and to contribute raising standards and the ‘professionalisation’ of the sector (DfES/Standards Unit 2004); however, even before their introduction concerns were raised about over-regulation (Lucas, 2004:49).
Despite a significant level of investment in the new standards, what eventually emerged has been subject to even greater criticism than the FENTO standards (e.g. see Lucas, 2007; Finlay et al 2007; Gleeson and James, 2007 and Simmons and Thompson 2007). Key features in this criticism have been the narrow concept of learning and skills, and the lack of recognition of both the wider dimensions of professional practice and the importance of knowledge. Contextualised within this literature, this paper argues that the detailed and prescriptive competency based structure of contemporary teacher training in the FE sector, together with wider regulation such as Ofsted and LLUK endorsement requirements, is productive of teachers who are instrumental and conformist but who lack the knowledge to engage with the concerns for social justice which are fundamental to working in the FE sector. In turn, these teachers deliver an instrumental and competency based vocational curriculum which, the paper argues, is complicit with other systems and structures in education in the reproduction of labour and of social class.
The paper also draws on literature addressing issues around assessment (Ecclestone, 2010) and professionalism (e.g. Gleeson and James, 2007; Bathmaker, 2006) as well as class based critiques of the FE system which draw on work by, amongst others, Avis, (2007), Atkins (2009) and Colley (2006). The arguments in this paper are also supported by a deconstruction of the current standards. This deconstruction has been used to identify what is – and is not – supported or promoted by the standards in the context of education and wider notions of professionalism and to problematise them in the context of contemporary literature
Clipping, Morgan State College, circa 1950
No full textMorgan State College adds 25 regular teachers, 4 substitutes to Faculty for the new year. These include Cyril F. Atkins, Oscar J. Chapman, Cleveland J. Franks, Leroy R. Posey, Clarence F. Stephens, Irene E. Diggs, Thomas P. Fraser, Maurice A. Lee, Roland C. McConnell, Donald G. Brandon, Mae B. Claytor, Norvell W. Hunter, Lydia W. Mussenden, Isador B. Ogelsby, Ulysses S. Stubbs Jr., Idel W. Taylor, Marian P. Wall, Isiah A. Woodward, Kenneth E. Brown, C. Philip Butcher, Rosalyn O. Furlonge, Madge B. Hibler, Ruth A. Matthews, Lucille P. Wade, Frank C. Bell, Vashti M. Grayson, Juanita G. Strake, and Alphonso C. Warrington
The Sunflower, v.80, no.06 (September 8, 1975)
No full textImages in this collection were made from commercially produced and digitized microfilm, may be of poor quality, and will be gradually replaced by copies digitized by Special Collections from original paper copies. Source material held by University Libraries Special Collections and University Archives; processed by the University Libraries Technical Services. Please contact Special Collections at [email protected] directly for help with low quality images.Article(s): Bennett warns educators purse strings are closing / Dan Bearth -- Records clerk ends 15 years at Wichita State / Bonnie Johnson -- Organization funds available -- Resident definition clarified by regents -- Media told to heed public’ s wants -- AWARE invites women to meeting -- What price peace? -- Stick your neck out -- Stick your pen out -- Just of 17th Street / Marsh Galloway -- Flying Dutchman Receives grant -- Contractors offer funding for construction students -- Prairie conservation meeting scheduled -- Dance weekend offered variety / R. Bretton Neff -- Army ROTC to sponsor rapelling [sic] show -- Shocker defense wins first tilt / Mike Shalin -- Shocker game plan cited / Steve PikePhotograph(s): Mrs. Lydia McFarland. p. 1 -- Rocky Garza is mobbed by his teammates after intercepting a West Texas State pass. / photo by Howard Rappaport. p. 7 -- Shocker quarterback Sam Atkins just after he plunged over from six inches for the winning touchdown. / photo by Howard Rappaport. p.
An approach to non-linear Bayesian forecasting problems with applications
No full textThis thesis is devoted to the analysis and modelling of time series and it is concentrated on models and techniques which are of practical value. In particular we developed a wide class of non-linear dynamic models which are useful in the handling of real life problems.
Initially we review the basic principles of Bayesian forecasting and the design of Dynamic Linear Models. The main body of the thesis attacks the problem of Normal non-linear estimation and forecasting. Some applications to the seasonal multiplicative model are exhaustively discussed. Following this we present the results of an application of Bayesian transfer response in Market Research. This application worked as the very first stimulus to extend the non-linear models to the exponential family.
Finally we discuss the concepts of stochastic transfer response modelling and associated sequential estimation, and we report some applications of the method and models for long term forecasting
Detective fiction in Cuban society and culture.
No full textPhDThe object of this thesis is to reach towards an understanding of Cuban society through a
study of its detective fiction and more particularly contemporary Cuban society through
the novels of the author and critic, Leonardo Padura Fuentes.
The method has been to trace the development of Cuban detective writing and to
read Padura Fuentes in the light of the work of twentieth century Western European
literary critics and philosophers including Raymond Williams, Antonio Gramsci, Terry
Eagleton, Roland Barthes, Jean Paul Sartre, Michel Foucault, Jean François Lyotard and
Jean Baudrillard in order to gain a better understanding of the social and historical
context from which this genre emerged.
By concentrating on the literary texts, I have explored readings which lead out into
an analysis of the broader philosophical, political and historical issues raised by the
Cuban revolution. Since it deals primarily with modes of deviance and notions of legality
and justice within the context of the modern state, detective fiction is particularly well
suited to this type of investigation. The intention is to show how this is as valid in the
Cuban context as it is in advanced capitalist societies where such research has already
been carried out with some success.
The thesis comprises an introduction, ten chapters and a conclusion. The chapters
are divided into three sections. Chapters 1 to 3 attempt a broad theoretical, historical and
socio-political analysis of the cultural reality within which the Cuban revolutionary
detective genre emerged. Chapters 4 to 6 analyse the Cuban detective narrative from its
inception in the early part of the twentieth century until the emergence of Leonardo
Padura Fuentes as the foremost exponent of the genre in Cuba after 1991. Chapters 7-
10 concentrate upon the work of Leonardo Padura Fuentes, offering a reading of his
detective tetralogy informed by the preceding discussion.
The contribution made by the thesis to knowledge of the subject is to build upon the
work of Seymour Menton and Amelia S. Simpson on the development of the Cuban
detective novel and to provide analyses of the pre-Revolutionary Cuban detective
narrative and the work of Leonardo Padura Fuentes for the first time in the English
language. The thesis concludes that the study of this popular genre in Cuba is of crucial
importance to the scholar who wishes to reach as full an understanding of the social
dynamics within that society as possible. In particular, it proves that Cuban detective
fiction provides a useful barometer of social change which records the shifts in the Cuban
Zeitgeist that have taken place over the past century
Expression, purification and characterization of the HIV-1 coreceptor CCR5 and its ligand RANTES and high-pressure NMR investigation of hydrogen bonds in biomolecules
No full textNuclear magnetic resonance spectroscopy is a very versatile technique for the investigation of biomolecular structures and dynamics. In this thesis, solution and solid state NMR methods have been applied to study a membrane protein and its interactions with a ligand and an antagonist, to characterize the thermodynamics of protein dimerization, and to observe changes in the hydrogen bond network of proteins and nucleic acids under the influence of high pressure.
The first part describes the expression, purification, and characterization of the membrane protein CCR5 and its ligand RANTES. The second part is concerned with the effect of pressure on the hydrogen bond network in proteins and nucleic acids.
The G protein-coupled receptor CCR5 is the major HIV-1 coreceptor and thus a very important target for the development of HIV-1 entry inhibitors. The large-scale expression and purification of CCR5, leading to 1 mg of pure protein per liter cell culture after purification, is described. The receptor's functionality is shown via recognition by a conformation-dependent antibody and by binding of the endogenous ligand RANTES.
The possibility to obtain large amounts of functional CCR5 overcomes a major bottleneck for the structural characterization of this membrane protein.
The receptor and its ligand were further characterized by NMR spectroscopy.
First heteronuclear solution state NMR spectra of selectively labeled CCR5 were obtained.
The interaction of the receptor with the chemokine RANTES was studied by solution NMR as well as in a lipid environment using solid state NMR experiments. In these experiments, binding of RANTES to CCR5 is observed.
Many chemokines undergo dimerization in the low micro- to millimolar range, but the biological relevance of this phenomenon is under debate. The temperature and pressure dependence of the RANTES monomer/dimer equilibrium was characterized by NMR spectroscopy. This study reveals the enthalpy and entropy contributions to RANTES dimerization. In addition, a pressure-induced unfolded state was observed for the first time.
A solely monomeric mutant of RANTES was designed and shown to inhibit HIV-1 infection in vitro. This is the basis for further studies of the complex between RANTES and CCR5 as well as CCR5-derived peptides.
Hydrogen bonds are extremely important to stabilize the structures of proteins and nucleic acids. In this thesis, methods to measure the scalar couplings across hydrogen bonds in these biomolecules are described. They were applied to study pressure-dependent changes in the hydrogen bond scalar couplings in ubiquitin. The most pressure-labile regions of the protein were identified.
These largely correspond to regions which are destabilized at elevated temperature.
Pressure- and temperature-dependent hydrogen bond scalar couplings have also been measured in a small RNA hairpin. The data indicate that the average pressure-induced changes of hydrogen bond length are similar in nucleic acids and proteins
Biomacromolecules
No full textTrauma is the leading cause of death for people ages 1-44, with blood loss comprising 60-70% of mortality in the absence of lethal CNS or cardiac injury. Immediate intervention is critical to improving chances of survival. While there are several products to control bleeding for external and compressible wounds, including pressure dressings, tourniquets, or topical materials (e.g., QuikClot, HemCon), there are no products that can be administered in the field for internal bleeding. There is a tremendous unmet need for a hemostatic agent to address internal bleeding in the field. We have developed hemostatic nanoparticles (GRGDS-NPs) that reduce bleeding times by ~50% in a rat femoral artery injury model. Here, we investigated their impact on survival following administration in a lethal liver resection injury in rats. Administration of these hemostatic nanoparticles reduced blood loss following the liver injury and dramatically and significantly increased 1 h survival from 40 and 47% in controls (inactive nanoparticles and saline, respectively) to 80%. Furthermore, we saw no complications following administration of these nanoparticles. We further characterized the nanoparticles' effect on clotting time (CT) and maximum clot firmness (MCF) using rotational thromboelastometry (ROTEM), a clinical measurement of whole-blood coagulation. Clotting time is significantly reduced, with no change in MCF. Administration of these hemostatic nanoparticles after massive trauma may help staunch bleeding and improve survival in the critical window following injury, and this could fundamentally change trauma care.DP2 OD007338/OD/NIH HHS/United StatesDP20D007338/DP/NCCDPHP CDC HHS/United State
Intravenous Hemostatic Nanoparticles Increase Survival Following Blunt Trauma Injury
No full textTrauma is the leading cause of death for people ages 1–44, with blood loss comprising 60–70% of mortality in the absence of lethal CNS or cardiac injury. Immediate intervention is critical to improving chances of survival. While there are several products to control bleeding for external and compressible wounds, including pressure dressings, tourniquets, or topical materials (e.g., QuikClot, HemCon), there are no products that can be administered in the field for internal bleeding. There is a tremendous unmet need for a hemostatic agent to address internal bleeding in the field. We have developed hemostatic nanoparticles (GRGDS-NPs) that reduce bleeding times by ~50% in a rat femoral artery injury model. Here, we investigated their impact on survival following administration in a lethal liver resection injury in rats. Administration of these hemostatic nanoparticles reduced blood loss following the liver injury and dramatically and significantly increased 1 h survival from 40 and 47% in controls (inactive nanoparticles and saline, respectively) to 80%. Furthermore, we saw no complications following administration of these nanoparticles. We further characterized the nanoparticles’ effect on clotting time (CT) and maximum clot firmness (MCF) using rotational thromboelastometry (ROTEM), a clinical measurement of whole-blood coagulation. Clotting time is significantly reduced, with no change in MCF. Administration of these hemostatic nanoparticles after massive trauma may help staunch bleeding and improve survival in the critical window following injury, and this could fundamentally change trauma care.The authors would like to acknowledge D Campbell L Wu and E Shoffstall for their contributions to this work and a NIH Director s New Innovator Award grant DP20D007338https://pubs.acs.org/doi/10.1021/bm301302
AN OVERVIEW OF FACTORS AFFECTING THE SIZE OF LOCAL GOVERNMENT
No full textThis paper reviews many factors affecting the size of local government. These factors include: current demographic trends and changes in alternative service delivery arrangements, theoretical schools of thought, evidence on economies of size, whether current local governments are managed efficiently, and legal and political factors.Public Economics,
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