111 research outputs found
Effectiveness of a professional development (PD) training on teacher self-efficacy
Hanako Shimamura presents her investigations on how self-efficacy of Early Childhood Education (ECE) teachers relates to instructional support and the impact of PD training on teacher self-efficacy. Presented at the Douglas College Research Café on February 17, 2022
Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing
SummarySpinal and bulbar muscular atrophy (SBMA), a progressive degenerative disorder, is caused by a CAG/glutamine expansion in the androgen receptor (polyQ AR). Recent studies demonstrate that skeletal muscle is an important site of toxicity that contributes to the SBMA phenotype. Here, we sought to identify critical pathways altered in muscle that underlie disease manifestations in AR113Q mice. This led to the unanticipated identification of gene expression changes affecting regulators of carbohydrate metabolism, similar to those triggered by denervation. AR113Q muscle exhibits diminished glycolysis, altered mitochondria, and an impaired response to exercise. Strikingly, the expression of genes regulating muscle energy metabolism is rescued following peripheral polyQ AR gene silencing by antisense oligonucleotides (ASO), a therapeutic strategy that alleviates disease. Our data establish the occurrence of a metabolic imbalance in SBMA muscle triggered by peripheral expression of the polyQ AR and indicate that alterations in energy utilization contribute to non-neuronal disease manifestations
Marchantiaceae
Notes on Marchantiaceae taxa in East Asia With the publication of novel and regionally recorded taxa, the Marchantiaceae in East Asia is represented by three well-recognized genera (Zheng & Shimamura 2022a), including 14 taxa (Bischler-Causse 1989; Long & Crandall-Stotler 2020; Xiang et al. 2016, 2022; Zheng & Shimamura 2020, 2022a, 2022b; Zheng & Long, 2023). Among them, some taxa doubtfully recorded in the Chinese bryoflora (Marchantia emarginata subsp. emarginata and M. stoloniscyphulus (Gao & Chang 1982: 114) Piippo 1990: 134) warrant a brief discussion in this study. Marchantia emarginata subsp. emarginata was first reported by Chao (1943, as “ M. palmata Nees ”) and subsequently recorded in some regional studies (Jia & He 2013; Xiong & Cao 2018) in China. However, Zheng (unpublished) found that (1) subgeneric classification of the M. emarginata complex is geographical rather than morphological, (2) there is excessive morphological diversity within the specimens identified as subsp. emarginata by the original author and (3) the distinguishing character of this subspecies (e.g., epidermal papillae and narrower appendages of ventral median scales) are not easily observed in some Southeast Asian specimens, indicating that the present treatments and morphological definition of subsp. emarginata are not tenable and need to be further reviewed. For M. stoloniscyphulus, Zheng et al. (unpublished) have been able to show that it is conspecific with M. papillata Raddi (1822: 20) subsp. grossibarba (Stephani 1894b: 221) Bischler (1989: 78) rather than being an independent species. Therefore, both taxa should be excluded from the following key.Published as part of Zheng, Tian-Xiong, Long, David G. & Shimamura, Masaki, 2023, Range extension of Marchantia formosana (Marchantiaceae, Marchantiophyta), with an updated key to Marchantiaceae taxa in East Asia, pp. 93-98 in Phytotaxa 612 (1) on page 96, DOI: 10.11646/phytotaxa.612.1.8, http://zenodo.org/record/830890
Letter from residents requesting prisoner release, February 18, 1944
Letter from residents requesting the release of two incarerees: Wataru Obara, and Hiroichi Shimamura, detained in army stockades at Tule Lake Camp.The Willard Schmidt collection, documents some of the administrative duties of Willard Schmidt, the Chief of Internal Security for the War Relocation Authority and the Tule Lake incarceration/segregation camp. This collection contains administrative records and photos documenting the Tule Lake camp, the largest incarceration camp with a peak population of 18,789 and with the most turbulent history. In 1943, the camp was turned into a segregation center to house "disloyal" Japanese Americans relocated from other camps based on their answers to a confusing loyalty questionnaire. The camp endured martial law from November 1943- Jan 1944 after escalating protests and unrest. The hostile environment of the camp lead to many incarcerees renouncing their American citizenship upon the end of incarceration, a process which took 14 years to reverse if they did not wish to be deported to Japan
OS9(5)-20(OS09W0059) Wireless Strain Monitoring of Tires Using Electric Capacitance Changes
Advances in solid oxide fuel cells and electronic ceramics
The Ceramic Engineering and Science Proceeding has been published by The American Ceramic Society since 1980. This series contains a collection of papers dealing with issues in bothtraditional ceramics (i.e., glass, whitewares, refractories, and porcelain enamel) and advanced ceramics. Topics covered in the area of advanced ceramic include bioceramics, nanomaterials, composites, solid oxide fuel cells, mechanical properties and structural design, advanced ceramic coatings, ceramic armor, porous ceramics, and more.Preface // Introduction // SOLID OXIDE FUEL CELLS // Effects of TiO2 Addition on Microstructure and Ionic Conductivity of Gadolinia-Doped Ceria Solid Electrolyte // Effect of Specific Surface Area and Particle Size Distribution on the Densification of Gadolinium Doped Ceria // Study on Sintering and Stability Issues of BaZr0.1Ce0.7Y0.1Yb0.1O3-Electrolyte for SOFCs // Sintering, Mechanical, Electrical and Oxidation Properties of Ceramic Intermetallic TiC-Ti3Al Composites from Nano-TiC Particles // Characteristics of Protective LSM Coatings on Cr-Contained Steels used as Metallic Interconnectors of Intermediated Temperature Solid Oxide Fuel Cells // Electrical and Microstructural Evolutions of La0.67Sr0.33MnO3 Coated Ferritic Stainless Steels after Long-Term Aging at 800 C // Structural and Electrochemical Performance Stability of Perovskite Fluorite Composite for High Temperature Electrochemical Devices // Durability of Lanthanum Strontium Cobalt Ferrite ((La0.60Sr0.40)0.95(Co0.20Fe0.80)O3-x) Cathodes in CO2 and H2O Containing Air // Fabrication of the Anode-Supported Solid Oxide Fuel Cell with Composite Cathodes and the Performance Evaluation upon Long-Term Operation // Development of Microtubular Solid Oxide Fuel Cells using Hydrocarbon Fuels // Highly Efficient Solid Oxide Electrolyzer and Sabatier System // SINGLE CRYSTALLINE MATERIALS FOR ELECTRICAL AND OPTICAL APPLICATIONS // The Effects of Excess Silicon and Carbon in SiC Source Materials on SiC Single Crystal Growth in Physical Vapor Transport Method // Progress of GaN Substrates Manufactured by VAS // Coilable Single Crystal Fibers of Doped-YAG for High Power Applications // Hydrothermal Crystal Growth and Applications // Reactive Atmospheres for Oxide Crystal Growth // Discussion on Polycrystals over Single Crystals for Optical Devices // Terahertz Time-Domain Spectroscopy Application to Non-Destructive Quality Evaluation of Industrial Crystalline Materials // Author Inde
Letter from incarcerees requesting release of prisoners, April 17, 1944
Letter from incarcerees requesting the release of 21 inmates from the army stockades at Tule Lake Camp. Names: Kazama, Masami; Shimada, Shunichi; Harauchi, Akio; Kusuda, Masanao; Gushiken, Yoshitsune; Gushiken, Yoshio; Matsumoto, Mitsuru; Matsumoto, Tsuneto; Masuoka, Hiro; Tarumoto, Sadaichi; Obara, Wataru; Shimamura, Hiroichi; Fujii, Yoshio; Aoki, Jin; Kurashige, Kenichi; Okata, Masanao; Nakahara, Tokushige; Morikawa, Masao; Morikawa, Shigeto; Yoshimura, Minoru; Takaishi, Awako; Takato, Jitsuo; Taniguchi, HitoshiThe Willard Schmidt collection, documents some of the administrative duties of Willard Schmidt, the Chief of Internal Security for the War Relocation Authority and the Tule Lake incarceration/segregation camp. This collection contains administrative records and photos documenting the Tule Lake camp, the largest incarceration camp with a peak population of 18,789 and with the most turbulent history. In 1943, the camp was turned into a segregation center to house "disloyal" Japanese Americans relocated from other camps based on their answers to a confusing loyalty questionnaire. The camp endured martial law from November 1943- Jan 1944 after escalating protests and unrest. The hostile environment of the camp lead to many incarcerees renouncing their American citizenship upon the end of incarceration, a process which took 14 years to reverse if they did not wish to be deported to Japan
Teaching adults to read better and faster : results from an experiment in Burkina Faso
Two cognitively oriented methods were tested in Burkina Faso to help illiterates learn to read more efficiently. These were (a) speeded reading of increasingly larger word units and (b) phonological awareness training to help connect letters to speech. Learners were given reading tests and a computerized reaction time test. Although the literacy courses were shortened by the arrival of rains and government delays, the piloted methods helped adults read better than those in the standard"control"classes. Learners enrolled in the experimental classes performed better on the outcome tests than did learners enrolled in control classes. Ninety percent of the possible comparisons between treatment classes and control classes favored classes receiving treatments, and 72 percent of the measurements in favor of treatments were statistically significant. The evidence suggests that phonological awareness training is particularly effective in situations where the training period was short, and that rapid reading was more advantageous in longer training situations. Overall, the results are indicative of the potential that scientifically backed methods have in making adult literacy instruction more effective. However, due to the short duration of the classes (3-4 months) learners apparently did not receive sufficient practice to consolidate skills. Literacy skills may still be prone to being forgotten if readers do not learn to read automatically and if opportunities to read are few.Curriculum&Instruction,Teaching and Learning,Nonformal Education,Primary Education,ICT Policy and Strategies,Nonformal Education,ICT Policy and Strategies,Primary Education,Teaching and Learning,Curriculum&Instruction
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