1,657 research outputs found
Portrait of author Jackson A. Graves, [s.d.]
No full textPhotographic portrait of author Jackson A. Graves, [s.d.]. Graves is shown from his upper torso to his head and is looking to the right. He is wearing a light-colored suit, a light shirt, and a dark tie with a square pattern. He has light-colored hair that is neatly combed and parted at left, a thick light mustache, and light eyebrows. There are large bags beneath his eyes and his ears are very big
Prediction of liver disease in patients whose liver function tests have been checked in primary care : model development and validation using population-based observational cohorts
No full textPublished by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewe
Simulation and Control of a Pneumatic Muscle Actuator for a Rehabilitation Robot
No full textThe perfomance of a pneumatic muscle actuator, invented by Jim Hennequin and used in a prototype wheelchair-mounted robot ann designed by the first author is reported. Experimental measurements were made of the output torque versus rotary motion and internal pressure. The torque available for a muscle of size 60 mm width by 90 mm length ranges from 1 to 15 Nm. The rotary stiffness of this muscle is 0.081 Nm/deg. A simulation model of the dynamic behaviour of the muscle attached to the robot arm using one-dimensional flow theory was written in ACSL (Advanced Continuous Simulation Language). The resultant simulation gives good agreement to within ± 5% of the experimental values. Control using proportional and a PID controller is shown to be effective
Painted portrait of Father Geronimo Boscana, O.F.M., author of Chinigchinich, [s.d.]
No full textPhotograph of a painted portrait of Father Geronimo Boscana, O.F.M., author of "Chinigchinich", [s.d.]. The friar is at center, is shown from his upper torso to his head and is looking slightly to the right. He is wearing a light-colored hooded robe with the hood pulled halfway up his head. He has some thin white hair but is mostly bald. Chinigchinich was an account of California Indian life, focused on the Indians near San Juan Capistrano
Portrait of James Laughlin, author of "This Is My Blood," [s.d.]
No full textPhotographic portrait of James Laughlin, author of "This Is My Blood," [s.d.]. A elderly man with smiling eyes turns his face toward the camera. He has a slight smile on his face, and a large nose, bushy eyebrows and slicked-back graying hair. He wears a light-colored suit, striped tie, and undergarment.; The book was to be published March 3, 1989 in a limited edition by The Yolla Bolly Press
Fields of activity significance scientific college students [Campos de significación de la actividad científica en estudiantes universitarios]
No full textThis study has as purpose to show the beliefs, attitudes, knowledge and stereotypes of university students about scientific research. In order to reach it, the author carried out an exercise based on associative questions, individual and group interviews and a multiple choice questionnaire that was proposed to 273 students enrolled at two university centers at Guadalajara University (Universidad de Guadalajara). The information was then analyzed by means of the mixed content technique (open answers) and the statistic program SPSS (multiple choice questionnaire). The results show that most of the interview students have erroneous conceptions about the scientific duty and a very imprecise picture about the scientist and the domain and space in which he/she works. Since those social representations have been built throughout the student's academic life by several media (formal and informal), the author considers that it is essential to analyze them in order to increase the interest about scientific activity amongst the students
Fields of activity significance scientific college students [Campos de significación de la actividad científica en estudiantes universitarios]
No full textThis study has as purpose to show the beliefs, attitudes, knowledge and stereotypes of university students about scientific research. In order to reach it, the author carried out an exercise based on associative questions, individual and group interviews and a multiple choice questionnaire that was proposed to 273 students enrolled at two university centers at Guadalajara University (Universidad de Guadalajara). The information was then analyzed by means of the mixed content technique (open answers) and the statistic program SPSS (multiple choice questionnaire). The results show that most of the interview students have erroneous conceptions about the scientific duty and a very imprecise picture about the scientist and the domain and space in which he/she works. Since those social representations have been built throughout the student's academic life by several media (formal and informal), the author considers that it is essential to analyze them in order to increase the interest about scientific activity amongst the students
Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markers
No full textThe detection of fibrosis within nonalcoholic fatty liver disease (NAFLD) is important for ascertaining prognosis and the stratification of patients for emerging therapeutic intervention. We validated the Original European Liver Fibrosis panel (OELF) and a simplified algorithm not containing age, the Enhanced Liver fibrosis panel (ELF), in an independent cohort of patients with NAFLD. Furthermore, we explored whether the addition of simple markers to the existing panel test could improve diagnostic performance. One hundred ninety-six consecutively recruited patients from 2 centers were included in the validation study. The diagnostic accuracy of the discriminant scores of the ELF panel, simple markers, and a combined panel were compared using receiver operator curves, predictive values, and a clinical utility model. The ELF panel had an area under the curve (AUC) of 0.90 for distinguishing severe fibrosis, 0.82 for moderate fibrosis, and 0.76 for no fibrosis. Simplification of the algorithm by removing age did not alter diagnostic performance. Addition of simple markers to the panel improved diagnostic performance with AUCs of 0.98, 0.93, and 0.84 for the detection of severe fibrosis, moderate fibrosis, and no fibrosis, respectively. The clinical utility model showed that 82% and 88% of liver biopsies could be potentially avoided for the diagnosis of severe fibrosis using ELF and the combined panel, respectively. The ELF panel has good diagnostic accuracy in an independent validation cohort of patients with NAFLD. The addition of established simple markers augments the diagnostic performance across different stages of fibrosis, which will potentially allow superior stratification of patients with NAFLD for emerging therapeutic strategie
The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI)
No full textBACKGROUND: Although liver function tests (LFTs) are routinely measured in primary care, raised levels in patients with no obvious liver disease may trigger a range of subsequent expensive and unnecessary management plans. The aim of this study was to develop and validate a prediction model to guide decision-making by general practitioners, which estimates risk of one year all-cause mortality in patients with no obvious liver disease.METHODS: In this population-based historical cohort study, biochemistry data from patients in Tayside, Scotland, with LFTs performed in primary care were record-linked to secondary care and prescription databases to ascertain baseline characteristics, and to mortality data. Using this derivation cohort a survival model was developed to predict mortality. The model was assessed for calibration, discrimination (using the C-statistic) and performance, and validated using a separate cohort of Scottish primary care practices.RESULTS: From the derivation cohort (n?=?95 977), 2.7% died within one year. Predictors of mortality included: age; male gender; social deprivation; history of cancer, renal disease, stroke, ischaemic heart disease or respiratory disease; statin use; and LFTs (albumin, transaminase, alkaline phosphatase, bilirubin, and gamma-glutamyltransferase). The C-statistic for the final model was 0.82 (95% CI 0.80-0.84), and was similar in the validation cohort (n?=?11 653) 0.86 (0.79-0.90). As an example of performance, for a 10% predicted probability cut-off, sensitivity?=?52.8%, specificity?=?94.0%, PPV?=?21.0%, NPV?=?98.5%. For the model without LFTs the respective values were 43.8%, 92.8%, 15.6%, 98.1%.CONCLUSIONS: The Algorithm for Liver Function Investigations (ALFI) is the first model to successfully estimate the probability of all-cause mortality in patients with no apparent liver disease having LFTs in primary care. While LFTs added to the model's discrimination and sensitivity, the clinical utility of ALFI remains to be established since LFTs did not improve an already high NPV for short term mortality and only modestly improved a very low PPV
Portrait of Helen Fiske Hunt Jackson, author of Ramona, [s.d.]
No full textPhotographic portrait of Helen Fiske Hunt Jackson, author of "Ramona", [s.d.]. Mrs. Jackson is pictured standing, wearing an elaborate dress with a huge bustle, made of what appears to be silk or satin. Her hands are folded across her waist while she looks to the right. She appears to be in her middle-age and wears the large locks of her curly hair pulled back from her face. She can be seen smiling, while a chair supports her dress to the right. Picture file card reads: "An American novelist, poet, and general writer, born at Amherst, mass. October 18, 1831; died at San Francisco, CA, August 12, 1885. She was the daughter of Professor Fiske, of Amherst. He first husband, Capt. E.B. Hunt, died in 1863. In 1870, she published a volume entitled "Verses". Her first prose volume, "Bits of Travel" (1872), was followed by "Bits of Talk About Home Matters" (1873), and "Bits of Travel at Home" (1878). In 1875 she married Mr. W.S. Jackson, of Colorado Springs. Here, she published "A Century of Dishonor", relating to the dealings of the U.S. Government with the Indians. This led to her appointment in 1883 as a special commissioner to examine into the condition and needs of the Mission Indians. After visiting the different tribes, she wrote "Ramona"(1884), a novel relating to the Mission Indians. Mrs. Jackson had previously written two novels in the "no Name" seires: "Mercy Philbric's Chioce" ["Choice"?] (1876) and "Hetty's Strange History"(1877). Besides these works, she published "The Story of Boon", a poem (1879), the training of children(1882), and several books for young people: "Nellie's Silver Mine" (1878), "Mammy Tittleback and her Family" (1881), and "The Hunter Cats of Connorloa" (1884). Since her death have appeared "Glimpses of Three Coasts", "Sonnets and Lyrics", "Zeph", a novel (1886), and "Between Whiles" (1887)"
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