123 research outputs found
Computer Modeling of Molecular Vibration Frequencies and its Application to the Modeling of Silane Compounds
Get PDFComputer modeling of molecular vibrational frequencies and its application to the modeling of silane compounds.
No full textClass: Chemistry 493; May 1997; 17 p
New species of Spirotrichonympha from reticulitermes and the relationships among genera in Spirotrichonymphea (Parabasalia)
No full textSpirotrichonymphea is a class of hypermastigote parabasalids defined by their spiral rows of many flagella. They are obligate hindgut symbionts of lower termites. Despite more than 100 yr of morphological and ultrastructural study, the group remains poorly characterised by molecular data and the phylogenetic positions and taxonomic validity of most genera remain in question. The genus Spirotrichonympha has been reported to inhabit several termite genera, including Reticulitermes, Coptotermes, and Hodotermopsis. The type species for this genus, Spirotrichonympha flagellata, was described from Reticulitermes lucifugus but no molecular data are yet available for this species. In this study, three new Spirotrichonympha species are described from three species of Reticulitermes. Their molecular phylogenetic position indicates that the genus is not monophyletic, as Spirotrichonympha species from Coptotermes, Paraneotermes, and Hodotermopsis branch separately. In contrast, the genus Holomastigotoides is monophyletic, as demonstrated using new sequences from Holomastigotoides species. The presence of Holomastigotoides in Prorhinotermes and the distinct phylogenetic positions of Spirotrichonympha from Reticulitermes and Coptotermes are consistent with a previously proposed symbiont fauna replacement in the ancestor of Reticulitermes. [ABSTRACT FROM AUTHOR]Peer reviewedfinal article publishedCoptotermeslower termitegut symbiontRhinotermitidaeProrhinotermesParaneotermesHeteroterme
<i>BRAF</i> inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma
No full text Pleomorphic xanthoastrocytomas can be very resistant to treatment if they progress after standard therapy with surgery and radiation. We present the case of a patient with a multiply recurrent pleomorphic xanthoastrocytoma which demonstrated a sustained partial response to a combination regimen of the BRAF inhibitor vemurafenib and tumor treating fields. The regimen proved tolerable and efficacious in this case. </jats:p
A Dangerous Preoccupation with Future Danger: Why Expert Predictions of Future Dangerousness in Capital Cases Are Unconstitutional
No full textIn Furman v. Georgia, the United States Supreme Court held that it was unconstitutional to administer the death penalty upon the sole, unguided discretion of juries. In response to Furman, some states amended their statutes to suggest or require that a jury assess the defendant\u27s future dangerousness before issuing a death sentence. Generally, this assessment is based on psychiatric expert testimony. This author explores the reliability and accuracy of psychiatric expert testimony of future dangerousness in light of the Court\u27s more recent Barefoot v. Estelle and Dauber, v. Merrell Dow Pharmaceuticals decisions. The author argues that because the death penalty is so extreme and utterly final, heightened standards of reliability and accuracy should be used when determining the admissibility of evidence at the sentencing phases of capital trials
Plasma viral loads and CD4 T cell dynamics are similar in male and female macaques.
No full text(a) Plasma viral loads (Limit of detection is 30 copies /ml of plasma) in male (n = 4) and female (n = 4) macaques at day 4 and 10 post SIV infection (PI). (b) Representative dot plots showing the discrimination of CD4 T cells and it subsets in peripheral blood. Naïve and memory CD4 T cells were discriminated based on the differential expression of CD28 and CD95 on CD4 T cells. The proportion of peripheral blood (c) CD3+CD20-CD4 T cells, (d) CD4+CD28+CD95- naïve CD4 T cells, (e) CD4+CD28+CD95+ central memory CD4 T cells, and (f) CD4+CD28-CD95+ effector memory CD4 T cells at day 0, 4 and 10 PI in male (n = 4) and female (n = 4) macaques. Error bars represent standard error.</p
Improved simulated ventilation with a novel tidal volume and peak inspiratory pressure controlling bag valve mask: A pilot study
Get PDFINTRODUCTION: The dangers of hyperventilation during resuscitation are well known. Traditional bag valve mask (BVM) devices rely on end users to control tidal volume (V(t)), rate, and peak inspiratory pressures (PIP) of ventilation. The Butterfly BVM (BBVM) is a novel device intending to give greater control over these parameters. The objective of this pilot study was to compare the BBVM against a traditional device in simulated resuscitations. METHODS: Senior emergency medicine residents and fellows participated in a three-phase simulation study. First, participants used the Ambu Spur II BVM in adult and pediatric resuscitations. V(t), PIP, and rate were recorded. Second, participants repeated the resuscitations after a brief introduction to the BBVM. Third, participants were given a longer introduction to the BBVM and were tested on their ability to adjust its various settings. RESULTS: Nineteen participants were included in the adult arm of the study, and 16 in the pediatric arm. The BBVM restricted V(t) delivered to a range of 4–8 ml/kg vs 9 ml/kg and 13 ml/kg (Ambu adult and Ambu pediatric respectively). The BBVM never exceeded target minute ventilations while the Ambu BVMs exceeded target minute ventilation in 2 of 4 tests. The BBVM failed to reliably reach higher PIP targets in one test, while the pediatric Ambu device had 76 failures of excessive PIP compared to 2 failures by the BBVM. CONCLUSION: The BBVM exceeded the Ambu Spur II in delivering appropriate V(t)s and in keeping PIPs below target maximums to simulated adult and pediatric patients in this pilot study
Witten's D4 Integrable Hierarchies Conjecture
Get PDFThe authors prove that the total descendant potential functions of the theory of Fan-Jarvis-Ruan-Witten for D-4 with symmetry group < J > and for D-4(T) with symmetry group G(max), respectively, are both tau-functions of the D-4 Kac-Wakimoto/Drinfeld-Sokolov hierarchy. This completes the proof, begun in the article by Fan-Jarvis-Ruan (2013), of the Witten Integrable Hierarchies Conjecture for all simple (ADE) singularities.the National Natural Science Foundation of China; the National Security Agency of USA; the Doctoral Fund of the Ministry of Education of ChinaSCI(E)中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)[email protected]; [email protected]; [email protected]; [email protected]; [email protected]
Current directions in videoconferencing tele-mental health research
Get PDFThe provision of mental health services via videoconferencing tele-mental health has become an increasingly routine component of mental health service delivery throughout the world. Emphasizing the research literature since 2003, we examine (a) the extent to which the field of tele-mental health has advanced the research agenda previously suggested and (b) implications for tele-mental healthcare delivery for special clinical populations. Previous findings have demonstrated that tele-mental health services are satisfactory to patients, improve outcomes, and are probably cost effective. In the very small number of randomized controlled studies that have been conducted to date, tele-mental health has demonstrated equivalent efficacy compared to face-to-face care in a variety of clinical settings and with specific patient populations. However, methodologically flawed or limited research studies are the norm, and thus the research agenda for tele-mental health has not been fully maximized. Implications for future research and practice are discussed
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