1,721,098 research outputs found

    A numerical method for the approximation of stable and unstable manifolds of microscopic simulators

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    We address a numerical methodology for the approximation of coarse-grained stable and unstable manifolds of saddle equilibria/stationary states of multiscale/stochastic systems for which a macroscopic description does not exist analytically in a closed form. Thus, the underlying hypothesis is that we have a detailed microscopic simulator (Monte Carlo, molecular dynamics, agent-based model etc.) that describes the dynamics of the subunits of a complex system (or a black-box large-scale simulator) but we do not have explicitly available a dynamical model in a closed form that describes the emergent coarse-grained/macroscopic dynamics. Our numerical scheme is based on the equation-free multiscale framework, and it is a three-tier procedure including (a) the convergence on the coarse-grained saddle equilibrium, (b) its coarse-grained stability analysis, and (c) the approximation of the local invariant stable and unstable manifolds; the later task is achieved by the numerical solution of a set of homological/functional equations for the coefficients of a polynomial approximation of the manifolds

    TRANSITION TO PARENTHOOD AFTER DONOR CONCEPTION

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    This study aims to examine donor conception (DC) mothers’ and fathers’ psychological status and their maternal and paternal mental representations (MRs) in the perinatal period, and to compare them with couples who conceived after Assisted Reproductive Technology with autologous gametes (AUT-ART), and with couples who conceived naturally (NC). All participants were followed longitudinally over their transition to parenthood at four-time points: around the 14th week of pregnancy, the 7th month of pregnancy, 1-2 months postpartum and 4-5 months postpartum. At the first assessment, the participant consisted of 85 NC mothers, 45 NC fathers, 28 DC mothers, 21 DC fathers, 35 AUT-ART mothers, and 14 AUT-ART fathers. To examine the parental psychological status, repeated measures ANOVA was performed on outcome variables to examine differences among the three groups of mothers and two groups of fathers (the sample of AUT-ART fathers were too small to perform statistical analysis), and within the four phases. The state anxiety was lower in DC mothers than in NC mothers, irrespectively of the time of assessment, while no statistically significant difference was found between the two groups of fathers. There were also no differences among the groups of mothers and fathers regarding the presence of anxiety symptomatology, trait anxiety, depression, parenting stress, and dyadic adjustment. The pregnancy-related anxiety was lower for DC mothers than both NC and AUT-ART mothers, irrespectively of the time of assessment. The pregnancy-related anxiety was lower for DC fathers than NC fathers, irrespectively of the time of assessment. ANCOVA showed that the prenatal attachment to the fetus was higher in AUT-ART mothers than in NC mothers and that the postnatal attachment to the baby was higher in DC mothers than NC mothers. No statistically significant differences between DC fathers and NC fathers were found in the prenatal attachment to the fetus, while the postnatal attachment to the baby was higher in DC fathers than NC fathers. To investigate the maternal and paternal MRs and detect the distribution of integrated/balanced, restricted/disinvested, and ambivalent/non-integrated categories among groups and across the four phases, 10 DC mothers, 10 DC fathers, 10 NC mothers, 10 NC fathers, and 10 AUT-ART mothers were selected (the sample of AUT-ART fathers was too small). This selection yielded 200 interviews (50 participants at 4 times each), which were transcribed and analysed, and a descriptive analysis was conducted. We found that all OD mothers, the vast majority of OD fathers and AUT-ART mothers had integrated balanced MRs, while NC mothers and NC fathers had more variegated results across the transition to parenthood. Moreover, we explored qualitatively the 10 non-biological mothers’ representation of resemblance with the child and representation of third-party reproduction. We reported that all 10 non-biological mothers found physical or psychological characteristics in common with the child, while the representation of third-party reproduction was more complex to elaborate. This work is supported by the University of Trieste and the Institute for Maternal and Child Health IRCCS Burlo Garofolo, and is part of a larger and still ongoing longitudinal study (N. of protocol RC 17/2018) involving couples in transition to parenthood after donor conception, directed by Prof. Giuseppe Ricci. The research was designed and supervised by Prof. Maria Anna Tallandini and Prof. Giuseppe Ricci. Patient recruitment, data collection, test assessment, transcription and analysis of the interviews were carried on by Lucia Roberta Russo, Liviana Zanchettin, and Margherita Battistella. Data analysis was performed by Lucia Roberta Russo and Prof. Giorgio Gronchi. Prof. Laura Vismara supervised the evaluation of the interviews, and Prof. Maria Anna Tallandini reviewed, on a sample basis, the evaluations as an external judge.This study aims to examine donor conception (DC) mothers’ and fathers’ psychological status and their maternal and paternal mental representations (MRs) in the perinatal period, and to compare them with couples who conceived after Assisted Reproductive Technology with autologous gametes (AUT-ART), and with couples who conceived naturally (NC). All participants were followed longitudinally over their transition to parenthood at four-time points: around the 14th week of pregnancy, the 7th month of pregnancy, 1-2 months postpartum and 4-5 months postpartum. At the first assessment, the participant consisted of 85 NC mothers, 45 NC fathers, 28 DC mothers, 21 DC fathers, 35 AUT-ART mothers, and 14 AUT-ART fathers. To examine the parental psychological status, repeated measures ANOVA was performed on outcome variables to examine differences among the three groups of mothers and two groups of fathers (the sample of AUT-ART fathers were too small to perform statistical analysis), and within the four phases. The state anxiety was lower in DC mothers than in NC mothers, irrespectively of the time of assessment, while no statistically significant difference was found between the two groups of fathers. There were also no differences among the groups of mothers and fathers regarding the presence of anxiety symptomatology, trait anxiety, depression, parenting stress, and dyadic adjustment. The pregnancy-related anxiety was lower for DC mothers than both NC and AUT-ART mothers, irrespectively of the time of assessment. The pregnancy-related anxiety was lower for DC fathers than NC fathers, irrespectively of the time of assessment. ANCOVA showed that the prenatal attachment to the fetus was higher in AUT-ART mothers than in NC mothers and that the postnatal attachment to the baby was higher in DC mothers than NC mothers. No statistically significant differences between DC fathers and NC fathers were found in the prenatal attachment to the fetus, while the postnatal attachment to the baby was higher in DC fathers than NC fathers. To investigate the maternal and paternal MRs and detect the distribution of integrated/balanced, restricted/disinvested, and ambivalent/non-integrated categories among groups and across the four phases, 10 DC mothers, 10 DC fathers, 10 NC mothers, 10 NC fathers, and 10 AUT-ART mothers were selected (the sample of AUT-ART fathers was too small). This selection yielded 200 interviews (50 participants at 4 times each), which were transcribed and analysed, and a descriptive analysis was conducted. We found that all OD mothers, the vast majority of OD fathers and AUT-ART mothers had integrated balanced MRs, while NC mothers and NC fathers had more variegated results across the transition to parenthood. Moreover, we explored qualitatively the 10 non-biological mothers’ representation of resemblance with the child and representation of third-party reproduction. We reported that all 10 non-biological mothers found physical or psychological characteristics in common with the child, while the representation of third-party reproduction was more complex to elaborate. This work is supported by the University of Trieste and the Institute for Maternal and Child Health IRCCS Burlo Garofolo, and is part of a larger and still ongoing longitudinal study (N. of protocol RC 17/2018) involving couples in transition to parenthood after donor conception, directed by Prof. Giuseppe Ricci. The research was designed and supervised by Prof. Maria Anna Tallandini and Prof. Giuseppe Ricci. Patient recruitment, data collection, test assessment, transcription and analysis of the interviews were carried on by Lucia Roberta Russo, Liviana Zanchettin, and Margherita Battistella. Data analysis was performed by Lucia Roberta Russo and Prof. Giorgio Gronchi. Prof. Laura Vismara supervised the evaluation of the interviews, and Prof. Maria Anna Tallandini reviewed, on a sample basis, the evaluations as an external judge

    L'unificazione dei due codici,civile e commerciale, e i suoi riflessi sul diritto pubblico

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    Saggio sviluppato dal testo dell'intervento al seminario su "La partizione pubblico-privato esiste ancora?" presso l'Istituito Luigi Sturz

    L'invalidità dell'atto amministrativo davanti al giudice penale. I delitti dei pubblici ufficiali contro la pubblica amministrazione.

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    La tipicità della fattispecie incriminatrice richiesta dall'art.25,2°co.Cost.impone di dare rilevanza alle modalità di condotta che alterino l'interesse espresso dall'art.97 Cost. nei soli limiti dati (art.27 Cost.) dalla significativa lesione dell'offesa al bene protetto. Ne risulta una difficile coordinazione tra due distinte riserve di legge, quella prevista dall'art.25,2° co.Cost. e quella che, all'art.97 Cost., rinvia a fattispecie a struttura aperta, rispetto alle quali la tutela penale si ponga come extrema ratio. La verifica dei limiti e delle tecniche del sindacato penale sull'illegittimità amministrativa fa riferimento a coordinate amministrative diverse secondo che la condotta amministrativa concreti i reati di abuso (falso ideologico,rifiuto di atti dell'ufficio), da un lato o quelli di corruzione(peculato,concussione), dall'altro.Il sindacato sull'abuso sanziona le devianze dalla disciplina del procedimento che siano idonee a cogliere quelle dai fini delle funzioni. Nella corruzione l'indagine è volta a rilevare momenti ed atti in cui può concretizzarsi la funzione, una pretermissione dell'interesse pubblico che è data dalla sua coincidenza con "il miglior beneficio del privato", formula rapportata non ai motivi del provvedimento ma agli scopi complessivi di un settore di intervento dato, che identificano una pluralità di destinatari, ad evidenziare del primo la sostanziale illegittimità. La verifica ha riguardo alla disciplina amministrativa di tre settori nei quali è più forte la pressione degli interessi (procedure selettive per l'accesso al rapporto d'impiego, appalti di forniture,beni e servizi,urbanistica).Ne emerge un quadro composito in cui atti illegittimi per il giudice amministrativo non toccano la soglia della rilevanza penale, ai fini dell'abuso, ed atti, passati al vaglio della legittimità amministrativa, sono componenti di una condotta illecita, com'è nel caso della corruzione. La coerenza, a livello penale, è data dalla tutela dell'amministrare, come corretta e doverosa estrinsecazione dell'attività amministrativa, quale momento dinamico destinato a concretizzarsi in atti amministrativi, aventi direttamente o indirettamente, un riflesso significativo rispetto al perseguimento dei fini che la p.a. deve realizzare per suo dovere istituzionale. Riguardo a quale tipo di invalidità, nullità o annullabilità, derivi all'atto amministrativo una volta qualificato come (fatto di)reato dal giudice penale, si rileva la diversa prospettiva che comporta nella più recente giurisprudenza amministrativa l'ascrizione al primo tipo in ordine a fattispecie, rispetto alle quali si affermava la sola annullabilità per eccesso di potere per irragionevolezza

    A REGRESSION TREE APPROACH FOR INVESTIGATING THE IMPACT OF HIGH SPEED RAIL ON TOURISTS'CHOICES

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    This paper provides a contribution to the international literature by applying regression tree methods to the analysis of the expected effects of the High Speed Rail project in Italy on the tourism market. This approach, as far as the author knows, has never been applied in this context. Tourism and transport information have been gathered for 99 Italian provinces during the 2006-2016 period. Tree-structured methods have been chosen as an application of regression models in which some explanatory variables are used as covariates to predict the dependent variable values on the basis of some decision rules. This approach establishes a casual effect between dependent and independent variables. The dependent variables chosen are the Italian and foreign tourists, and the number of overnights spent by Italians and foreigners. Among the independent variables are the presence of HSR, the presence of first-level airport hubs and the number of operating bases of low-cost airlines; among the attractiveness variables are the GDP, the number of attractions in a given province, the presence of the sea, the population and the percentage of unemployment. The main outcome of this study is that HSR affects the tourism market
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