1,721,091 research outputs found
MCRs to APIs: Tailoring Multicomponent Reactions for the Production of Pharmaceuticals
Get PDFOrru, R.V.A. [Promotor]Ruijter, E. [Copromotor
Isocyanides' Latest Trick: Palladium-Catalyzed Imidoylative Cross-Coupling Reactions
Get PDFOrru, R.V.A. [Promotor]Ruijter, E. [Copromotor
Off the Beaten Path: Atypical Products of Ugi and Passerini Reactions
Get PDFOrru, R.V.A. [Promotor]Ruijter, E. [Copromotor
Biocatalysis & Multicomponent Reactions: The Ideal Synergy: Asymmetric Synthesis of Substituted Proline Derivatives
Get PDFOrru, R.V.A. [Promotor]Groen, M.B. [Promotor]Ruijter, E. [Copromotor
Tryptamine-Derived Isocyanides I Have Known and Loved: From Multicomponent Reactions to Natural Product Synthesis
Get PDFOrru, R.V.A. [Promotor]Ruijter, E. [Copromotor
C2-functionalized 2-imidazolidines and 2-imidazolines Multicomponent Synthesis and Synthetic Potential
Get PDFOrru, R.V.A. [Promotor]Groen, M.B. [Promotor]Ruijter, E. [Copromotor
Stereoselective Syntheses of 2-Imidazolines
Get PDFOrru, R.V.A. [Promotor]Lammertsma, K. [Promotor]Slootweg, J.C. [Copromotor]Ruijter, E. [Copromotor
Multicomponent Approaches to Molecular Diversity & Complexity
Get PDFOrru, R.V.A. [Promotor]Groen, M.B. [Promotor]Ruijter, E. [Copromotor
Design and Synthesis of Photoactive Molecules
Get PDFOrru, R.V.A. [Promotor]Lammertsma, K. [Promotor]Ehlers, A.W. [Copromotor]Ruijter, E. [Copromotor
Molecular changes associated with prostate cancer development.
No full textThe epidemiologic characteristics of prostate cancer (PCa) have been recognized for several decades. It is of great importance to understand the factors responsible for prostate carcinogenesis, why some carcinomas remain "clinically silent" during life, whereas other tumors progress to present clinically and may lead to PCa-related death. A better understanding of these mechanisms in molecular genetic terms should point to more rational approaches to disease prevention, intervention and treatment. The aim of this review is to provide a comprehensive overview of the current state of knowledge regarding the molecular alterations of PCa
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