4,442 research outputs found
The role of Plasmodium falciparum var genes in malaria in pregnancy
No full textSequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified
sj-docx-1-cde-10.1177_21651434231223435 – Supplemental material for Secondary Transition Interventions in Rural Communities: A Systematic Literature Review
No full textSupplemental material, sj-docx-1-cde-10.1177_21651434231223435 for Secondary Transition Interventions in Rural Communities: A Systematic Literature Review by Alan S. McLucas, William J. Therrien and Dawn A. Rowe in Career Development and Transition for Exceptional Individuals</p
sj-docx-2-cde-10.1177_21651434231223435 – Supplemental material for Secondary Transition Interventions in Rural Communities: A Systematic Literature Review
No full textSupplemental material, sj-docx-2-cde-10.1177_21651434231223435 for Secondary Transition Interventions in Rural Communities: A Systematic Literature Review by Alan S. McLucas, William J. Therrien and Dawn A. Rowe in Career Development and Transition for Exceptional Individuals</p
sj-pdf-1-trr-10.1177_03611981221083310 – Supplemental material for Impact of Improved Density on Pavement Design Response for Low-Volume Roads/Non-Primary Routes
No full textSupplemental material, sj-pdf-1-trr-10.1177_03611981221083310 for Impact of Improved Density on Pavement Design Response for Low-Volume Roads/Non-Primary Routes by Jason Bausano, Phillip Blankenship and Geoffrey Rowe in Transportation Research Record</p
sj-pdf-1-smm-10.1177_09622802231188516 - Supplemental material for Bivariate copula regression models for semi-competing risks
No full textSupplemental material, sj-pdf-1-smm-10.1177_09622802231188516 for Bivariate copula regression models for semi-competing risks by Yinghui Wei, Małgorzata Wojtyś, Lexy Sorrell and Peter Rowe in Statistical Methods in Medical Research</p
sj-docx-1-mrx-10.1177_01979183241242445 - Supplemental material for Assessing the Differentiated Impacts of COVID-19 on the Immigration Flows to Europe
No full textSupplemental material, sj-docx-1-mrx-10.1177_01979183241242445 for Assessing the Differentiated Impacts of COVID-19 on the Immigration Flows to Europe by Miguel González-Leonardo, Francisco Rowe, Michaela Potančoková and Anne Goujon in International Migration Review</p
sj-docx-2-jiv-10.1177_08862605221111411 – Supplemental material for Sexual, Physical, and Emotional Maltreatment in Childhood Are Differentially Associated With Sexual and Physical Revictimization in Adulthood
No full textSupplemental material, sj-docx-2-jiv-10.1177_08862605221111411 for Sexual, Physical, and Emotional Maltreatment in Childhood Are Differentially Associated With Sexual and Physical Revictimization in Adulthood by Jessica Rowe, Jasmine Chananna, Simone Cunningham and Kate L. Harkness in Journal of Interpersonal Violence</p
sj-pdf-1-tva-10.1177_15248380221075087 – Supplemental Material for Links of Adversity in Childhood With Mental and Physical Health Outcomes: A Systematic Review of Longitudinal Mediating and Moderating Mechanisms
No full textSupplemental Material, sj-pdf-1-tva-10.1177_15248380221075087 for Links of Adversity in Childhood With Mental and Physical Health Outcomes: A Systematic Review of Longitudinal Mediating and Moderating Mechanisms by George Kelvin Hales, Agata Debowska, Richard Rowe and Zeliha Ezgi Saribaz in Trauma, Violence, & Abuse</p
sj-docx-1-jiv-10.1177_08862605221111411 – Supplemental material for Sexual, Physical, and Emotional Maltreatment in Childhood Are Differentially Associated With Sexual and Physical Revictimization in Adulthood
No full textSupplemental material, sj-docx-1-jiv-10.1177_08862605221111411 for Sexual, Physical, and Emotional Maltreatment in Childhood Are Differentially Associated With Sexual and Physical Revictimization in Adulthood by Jessica Rowe, Jasmine Chananna, Simone Cunningham and Kate L. Harkness in Journal of Interpersonal Violence</p
sj-docx-2-hej-10.1177_00178969231191085 – Supplemental material for Canadian cannabis education resources to support youth health literacy: A scoping review and environmental scan
No full textSupplemental material, sj-docx-2-hej-10.1177_00178969231191085 for Canadian cannabis education resources to support youth health literacy: A scoping review and environmental scan by Emily J. Howe, Lisa D Bishop, Bethany S. Torraville, Emily C. Rowe, Eden Kinzel and Jennifer R. Donnan in Health Education Journal</p
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