1,721,042 research outputs found

    Multidisciplinary “Boot Camp” Training in Cellular Bioengineering to Accelerate Research Immersion for REU Participants

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    Research Experiences for Undergraduates (REU) sites widely serve as the first major research gateway for undergraduates seeking a structured research experience. Given their lack of prior research skills, and the highly compressed duration of the REU programs, these students frequently encounter barriers to a seamless transition into a new laboratory environment. We hypothesized that the design of a unified short course on laboratory and analysis techniques could serve as a pivotal orientation experience. Our goal was to rapidly align student expertise to their summer research goals while also integrating the student participants into a cohesive learning community. This article discusses the design and outcomes of a Cellular Bioengineering Boot Camp, which is offered at the outset of the 10-week REU site at Rutgers. The Boot Camp provides hands-on, supervised training for techniques and procedures that are common among projects. The training establishes a common language and baseline for the REU students and allows their first laboratory experiences to be with each other, and creates an immediate network of peers and mentors. Surveys before and after the Boot Camp and at the end of the summer indicated a significant improvement in student proficiency in the techniques that was retained throughout the summer. We believe that the Boot Camp approach can be tailored to the specifics of each REU site and its associated projects and research foci.Peer reviewe

    Targeting tumor metastases: drug delivery mechanisms and technologies

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    Primary sites of tumor are the focal triggers of cancers, yet it is the subsequent metastasis events that cause the majority of the morbidity and mortality. Metastatic tumor cells exhibit a phenotype that differs from that of the parent cells, as they represent a resistant, invasive subpopulation of the original tumor, may have acquired additional genetic or epigenetic alterations under exposure to prior chemotherapeutic or radiotherapeutic treatments, and reside in a microenvironment differing from that of its origin. This combination of resistant phenotype and distal location make tracking and treating metastases particularly challenging. In this review, we highlight some of the unique biological traits of metastasis, which in turn, inspire emerging strategies for targeted imaging of metastasized tumors and metastasis-directed delivery of therapeutics.Peer reviewe

    Leo SANTIFALLER. Nikolaus Liebental und seine Chronik der Aebte des Breslauer St. Vinzenzstiftes . (Tongerloo, Analecta Praemonstratensia, t. XXV, 1949)

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    Roth Charles. Leo SANTIFALLER. Nikolaus Liebental und seine Chronik der Aebte des Breslauer St. Vinzenzstiftes . (Tongerloo, Analecta Praemonstratensia, t. XXV, 1949). In: Bibliothèque de l'école des chartes. 1955, tome 113. p. 342

    Dafydd EVANS. Lanier. Histoire d'un mot. Genève, Librairie Droz, 1967. (" Publications romanes et françaises" n° XCIII.)

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    Roth Charles. Dafydd EVANS. Lanier. Histoire d'un mot. Genève, Librairie Droz, 1967. (" Publications romanes et françaises" n° XCIII.). In: Bibliothèque de l'école des chartes. 1967, tome 125, livraison 2. pp. 473-474

    Festschrift Karl Schwarber. Beiträge zur schweizerischen Bibliotheks-, Buch- und Gelehrtengeschichte zum 60. Geburtstag am 22. November 1949 dargebracht. Bale, Benno Schwabe, 1949.

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    Roth Charles. Festschrift Karl Schwarber. Beiträge zur schweizerischen Bibliotheks-, Buch- und Gelehrtengeschichte zum 60. Geburtstag am 22. November 1949 dargebracht. Bale, Benno Schwabe, 1949.. In: Bibliothèque de l'école des chartes. 1950, tome 108. pp. 177-178

    Christine de Pisan. Le livre du corps de policie. Édition critique par Robert- H. Lucas. Genève, Librairie Droz, 1967. (Textes littéraires français, n° 145.)

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    Roth Charles. Christine de Pisan. Le livre du corps de policie. Édition critique par Robert- H. Lucas. Genève, Librairie Droz, 1967. (Textes littéraires français, n° 145.). In: Bibliothèque de l'école des chartes. 1968, tome 126, livraison 1. pp. 248-250

    Leo SANTIFALLER. Nikolaus Liebental und seine Chronik der Aebte des Breslauer St. Vinzenzstiftes . (Tongerloo, Analecta Praemonstratensia, t. XXV, 1949)

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    Roth Charles. Leo SANTIFALLER. Nikolaus Liebental und seine Chronik der Aebte des Breslauer St. Vinzenzstiftes . (Tongerloo, Analecta Praemonstratensia, t. XXV, 1949). In: Bibliothèque de l'école des chartes. 1955, tome 113. p. 342

    Jean-Charles Payen. Le motif du repentir dans la littérature française médiévale (des origines à 1230). Genève, Librairie Droz, 1967. (Publications romanes et françaises, XGVIII.)

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    Roth Charles. Jean-Charles Payen. Le motif du repentir dans la littérature française médiévale (des origines à 1230). Genève, Librairie Droz, 1967. (Publications romanes et françaises, XGVIII.). In: Bibliothèque de l'école des chartes. 1970, tome 128, livraison 2. pp. 431-434

    Jean Rychner. Formes et structures de la prose française médiévale. L'articulation des phrases narratives dans la « Mort Artu ». Neuchâtel, Faculté des lettres, et Genève, Droz, 1970. In-8°, 259 pages. (Université de Neuchâtel. Recueil de travaux publiés par la Faculté des lettres, 32e fascicule.)

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    Roth Charles. Jean Rychner. Formes et structures de la prose française médiévale. L'articulation des phrases narratives dans la « Mort Artu ». Neuchâtel, Faculté des lettres, et Genève, Droz, 1970. In-8°, 259 pages. (Université de Neuchâtel. Recueil de travaux publiés par la Faculté des lettres, 32e fascicule.). In: Bibliothèque de l'école des chartes. 1973, tome 131, livraison 2. pp. 622-625

    Roth, Charles M.

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