70 research outputs found
Black Industrial Noise, Ultima 2024
No full textPress Release from Ultima website:
"A radical ‘essay-concert’ reclaiming a post-colonial lineage of techno and noise. Black Industrial/Noise is an extended event taking over Henie Onstad Kunstsenter. Compelling experimental electronic music and noise artists and thinkers present a continuous flow of live music and talk, within a loosely defined concept of ‘Black Industrialism’.
Trevor Mathison and Gary Stewart have been in search of a black avantgarde since the 1980s. As the duo Dubmorphology they make experimental audio-visual installations and performances that examine the relationship between culture, history and creativity, reworking historical, political and scientific archives. Theorist and artist Kodwo Eshun is the author of the acclaimed book on music and Afrofuturism, More Brilliant Than the Sun (1998). He will give a performance-lecture outlining the aesthetic of Black Industrialism.
Nkisi is a producer, live musician, DJ and curator born in Congo, raised in Belgium. Her intense sonics are influenced by ancient Kongo rhythms, noise, the planetary electromagnetic grid, and experimental improvisation. South London’s Klein is an electronic composer with a Nigerian background. She specialises in grainy pop collages with R&B-inspired vocals, manipulated samples and metallic drones. As well as collaborating with Laurel Halo she has released music on the Hyperdub label and composed music for film.
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod-2
No full text<p><b>Copyright information:</b></p><p>Taken from "Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod"</p><p>BMC Gastroenterology 2006;6():8-8.</p><p>Published online 23 Feb 2006</p><p>PMCID:PMC1434748.</p><p>Copyright © 2006 Mathison and Shaffer; licensee BioMed Central Ltd.</p>ground squirrel fed either a low (0.027%; A) or a high (1%; B) cholesterol diet. Hexamethonium was added to the jejunal tissue segments 10 min before constructing a cumulative dose-response curve to the cholinergic agonist, carbachol. N = 5–6
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod-0
No full text<p><b>Copyright information:</b></p><p>Taken from "Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod"</p><p>BMC Gastroenterology 2006;6():8-8.</p><p>Published online 23 Feb 2006</p><p>PMCID:PMC1434748.</p><p>Copyright © 2006 Mathison and Shaffer; licensee BioMed Central Ltd.</p> vs. enriched (1%; High) cholesterol diet for animals treated with either vehicle (A) or tegaserod (B). Cumulative dose-response curve to carbachol were constructed. * High greater than Low (P < 0.05); N = 8–9
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod-1
No full text<p><b>Copyright information:</b></p><p>Taken from "Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod"</p><p>BMC Gastroenterology 2006;6():8-8.</p><p>Published online 23 Feb 2006</p><p>PMCID:PMC1434748.</p><p>Copyright © 2006 Mathison and Shaffer; licensee BioMed Central Ltd.</p> & D) cholesterol diet. The animals were treated with either vehicle (A & B) or tegaserod (C & D). The action potential blocker tetrodotoxin (TTX; 10M) was added to the jejunal tissue segments 10 min before constructing a cumulative dose-response curve to the cholinergic agonist, carbachol. * TTX greater than No TTX (P < 0.05). N = 8–9
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod-3
No full text<p><b>Copyright information:</b></p><p>Taken from "Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HTagonist – tegaserod"</p><p>BMC Gastroenterology 2006;6():8-8.</p><p>Published online 23 Feb 2006</p><p>PMCID:PMC1434748.</p><p>Copyright © 2006 Mathison and Shaffer; licensee BioMed Central Ltd.</p>w) vs. enriched (1%; High) cholesterol diet for animals treated with vehicle. (B) Effects of tetrodotoxin (TTX) on cholinergic contractions of the ileum of ground squirrels fed a high (1%) cholesterol diet and treated with vehicle. The action potential blocker tetrodotoxin (TTX; 10M) was added to the jejunal tissue segments 10 min before constructing a cumulative dose-response curve to the cholinergic agonist, carbachol. N = 8–9
Submandibular gland rat-1 peptides: a combined biological and computational approach to understanding biological activity
No full textBibliography: p. 112-123
NEURONIC SYSTEM INSIDE NEURONS: MOLECULAR BIOLOGY AND BIOPHYSICS OF NEURONAL MICROTUBULES
No full textNeurons are highly specialized cells that input, process, store and output information. Interneuronal communication is achieved in four basic ways: (i) Ca2+ evoked exocytosis with chemical neurotransmission, (ii) gap junction electrotonic coupling, (iii) secretion of neurosteroids, nitric oxide and derivatives of the arachidonic acid acting in paracrine manner, and (iv) cellular adhesive protein interactions with scaffold protein reorganization. Central structure integrating these anisomorphic signals is the neuronal cytoskeleton that is considered to be both sensitive to the local electromagnetic field and prone to intense biochemical modification. With the use of biophysical modeling we have shown that the local electromagnetic field interaction with neuronal microtubules could result in formation of dissipationless waves (solitons) of tubulin tail conformational states that propagate along the microtubule outer surface. Soliton collisions may subserve the function of elementary computational gates and the output of the computation performed by the microtubules may be achieved by the energase action of the tubulin tails that control microtubule-associated protein and motor protein attachment/detachment on the microtubule outer surface
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT<sub>4 </sub>agonist – tegaserod
No full textAbstract Background Excess cholesterol in bile and in blood is a major risk factor for the respective development of gallbladder disease and atherosclerosis. This lipid in excess negatively impacts the functioning of other smooth muscles, including the intestine. Serotonin is an important mediator of the contractile responses of the small intestine. Drugs targeting the serotonin receptor are used as prokinetic agents to manage intestinal motor disorders, in particular irritable bowel syndrome. Thus, tegaserod, acting on 5-HT4 receptor, ideally should obviate detrimental effects of excessive cholesterol on gastrointestinal smooth muscle. In this study we examined the effect of tegaserod on cholesterol-induced changes in the contractile responses of intestinal smooth muscle. Methods The effects of a high cholesterol (1%) diet on the in vitro contractile responses of jejunal longitudinal smooth muscle from Richardson ground squirrels to the cholinergic agonist carbachol were examined in the presence or absence of tetrodrodotoxin (TTX). Two groups of animals, fed either low (0.03%) or high cholesterol rat chow diet, were further divided into two subgroups and treated for 28 days with either vehicle or tegaserod. Results The high cholesterol diet increased, by nearly 2-fold, contractions of the jejunal longitudinal smooth muscle elicited by carbachol. These cholinergic contractions were mediated by muscarinic receptors since they were blocked by scopolamine, a muscarinic receptor antagonist, but not by the nicotinic receptor antagonist, hexamethonium. Tegaserod treatment, which did not affect cholinergic contractions of tissues from low cholesterol fed animals, abrogated the increase caused by the high cholesterol diet. With low cholesterol diet TTX enhanced carbachol-evoked contractions, whereas this action potential blocker did not affect the augmented cholinergic contractions seen with tissues from animals on the high cholesterol diet. Tegaserod-treatment removed the effects of a high cholesterol diet on neuronal muscarinic receptors, as the potentiating effect of TTX on carbachol-elicited contractions was maintained in these animals. Conclusion A high cholesterol diet causes significant changes to cholinergic neurotransmission in the enteric nerves of the jejunum. The mechanisms by which these effects of cholesterol are reversed by tegaserod are unknown, but relate to removal of an inhibitory effect of cholesterol on enteric nerves.</p
Modification by Cyclic AMP and Phosphodiesterase Inhibitors of Potassium-Stimulated Vasopressin Release from the Isolated Neural Lobe and the Hypothalamo-Neurohypophysial System in vitro
No full textTilling the garden of joy/sorrow: A poetic inquiry into the rhizomatic complexities of growing into and through collective spaces
No full textA pilot research project turned ongoing program sought to explore the experience of participating in an inclusive Campus Community Garden. In the confines of institutional research the project undertook a specific focus on uncovering the perceived benefits and barriers to participating preschoolers, older adults, individuals with mixed abilities and their caregivers from residential and intermediate care facilities. This paper describes a parallel exploration as an occurrent act of art making; an evolving rhizomatic process of poetic reflection on images and privileged notes from the field. In this work, the authors uncover the shape, movement, and colour of the joy/sorrow of tilling the garden through creative expression
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