2,846 research outputs found
Ernst Weiss
Digital ImageThe Austrian author Ernst Weiss was born in 1882 in Brno. He died 1940 in Paris
Harvey Weiss Correspondence
Entries include a typed letter from the Maine State Library to New York children\u27s book author Harvey Weiss introducing the Maine Author Collection and notice that a description of his book would appear in Maine Library Association Bulletin, a typed letter from Weiss on personal stationery presenting a copy of Twenty-Four And Stanley, and a typed letter from the Maine State Library concerning the irrepressible Stanley and on receipt of the book for the Maine Author collection
Malcolm E. and Ann E. Weiss Correspondence
Entry is a typed letter of reply from math and science children\u27s book author Malcolm E. Weiss on his personal stationery concerning a request for a copy of his book 666 Jellybeans! All That? for the Maine Author Collection and additionally the attempt of Weiss to send a copy of a Young Math Series book Solomon Grundy, Born on Oneday from the publisher, a defense for an overdue book, and a list of books written by his wife, history and social studies children\u27s author Ann E. Weiss as well as a list of his own titles at this time
A Method for Fast, High-Precision Characterization of Synthetic Biology Devices
Engineering biological systems with predictable behavior is a foundational goal of synthetic biology. To accomplish this, it is important to accurately characterize the behavior of biological devices. Prior characterization efforts, however, have generally not yielded enough high-quality information to enable compositional design. In the TASBE (A Tool-Chain to Accelerate Synthetic Biological Engineering) project we have developed a new characterization technique capable of producing such data. This document describes the techniques we have developed, along with examples of their application, so that the techniques can be accurately used by others
Kurt R. Weiss
Dr. Kurt R. Weiss is an associate professor in the University of Pittsburgh Department of Orthopaedic Surgery, Division of Musculoskeletal Oncology. He has joint appointments in Surgical Oncology and Pathology. He serves as an Advisory Dean for the University of Pittsburgh School of Medicine and as Vice Chair of Translational Research for his Department. His research career began as an undergraduate student at Notre Dame when he worked in the Ferguson Laboratory with Dr. Christopher Evans. During medical school at Jefferson Medical College, he performed a summer research internship with Dr. Eugenie Kleinerman at the University of Texas MD Anderson Cancer Center in Houston. Between his second and third years of medical school he participated in the Howard Hughes Medical Institute/National Institutes of Health Research Scholars Program where he worked in Dr. Lee Helman’s Laboratory in the National Cancer Institute (NCI) Pediatric Oncology Branch. During residency he performed original osteosarcoma research during his lab year with Dr. Johnny Huard. After his fellowship in Musculoskeletal Oncology at the University of Toronto with Drs. Jay Wunder and Peter Ferguson, Dr. Weiss was recruited back to Pittsburgh by his Chairman, Dr. Freddie Fu, as faculty and started his own Lab.
The Musculoskeletal Oncology Laboratory (MOL) is focused on sarcoma metastatic potential. Dr. Weiss’s team of PhD collaborators, residents, medical students, undergraduate students, and technicians perform basic and translational sarcoma research experiments. Much of this work is accomplished with samples from the Musculoskeletal Oncology Tumor Registry and Tissue Bank (MOTOR) that Dr. Weiss and his clinical partners established in 2012. The MOTOR now holds over 16,000 unique samples from over 600 sarcoma patients with clinical annotation, making it one of the largest sarcoma tissue repositories in the country. This resource provides vital biological reagents for both intramural and extramural sarcoma investigators who collaborate with the MOL.
Dr. Weiss is an author on over 80 peer-reviewed publications. He recently finished his term as Research Committee Chair for the Musculoskeletal Tumor Society, the largest professional society for musculoskeletal oncology surgeons on the continent of North America. He is on the Mentorship Committee for the Connective Tissue Oncology Society, for which he has also served on the Board of Directors. He was recently named to the Scientific Steering Committee of the Sarcoma Alliance for Research through Collaboration (SARC), the largest private supporter of sarcoma clinical trials in the world. He has taught at the Orthopedic Research Society grant writing course for many years. Dr. Weiss is a regular reviewer for NCI grant applications and was on the inaugural Programmatic Panel for the Department of Defense Rare Cancers Research Program. His funding sources have included K08 and R21 awards from the NCI as well as the support of numerous foundations including the Orthopedic Research and Education Foundation and the Connective Tissue Oncology Society. Dr. Weiss is a founding member of the Pittsburgh Cure Sarcoma (PCS) patient advocacy group, as well as the Pittsburgh Sarcoma Research Collaborative (PSaRC).https://openworks.mdanderson.org/kleinermanbios/1004/thumbnail.jp
Peter Weiss, Spain: Peter Weiss, Painting
Peter Weiss, España: Peter Weiss, Pintura, vincula dos aspectos poco tratados en torno a la figura del pintor y dramaturgo alemán Peter Weiss (1916-1982). En primer lugar, redescubre la relación que el autor mantiene con España a raíz del análisis de documentos relevantes. Por otro lado, llama la atención sobre la producción gráfica y la obra pictórica de un dramaturgo que ve el mundo como un pintor contemporáneo, como un sujeto moderno.Peter Weiss, Spain: Peter Weiss, Painting, links two aspects little treated concerning the figure of the painter and German playwright Peter Weiss (1916-1982). First, it re-discovers the relation that the author supports with Spain following the analysis of relevant documents. On the other hand, it calls the attention on the graphical production and the pictorial work of a playwright who sees the world as a contemporary painter, as a modern subject
Films by Peter Weiss
This doctoral thesis deals with Peter Weiss’ (1916-1982) films and some of his never finished attempts. The focus is in general on Weiss’ film work activities in the 1950’s, when film held the very central place in his works of art. The intention has been to interrogate what short films Peter Weiss made and to find out the meaning and the role of film in the life of the artist Peter Weiss. The conclusion is that Peter Weiss fought with personal difficulties in expressing himself in a language — a language of words and a language of signs — because it is assumed that Peter Weiss carried a very strong will to become an author. In order to “conquer the words” Weiss exercised himself in describing all kinds of worlds — an interior one as well as an exterior one. That explains why he dealt with surrealist psychological subjects and documentary forms while making films
Symplectic Weiss calculi
We provide two candidates for symplectic Weiss calculus based on two
different, but closely related, collections of groups. In the case of the
non-compact symplectic groups, i.e., automorphism groups of vector spaces with
symplectic forms, we show that the calculus deformation retracts onto unitary
calculus as a corollary of the fact that Weiss calculus only depends on the
homotopy type of the groupoid core of the diagram category. In the case of the
compact symplectic groups, i.e., automorphism groups of quaternion vector
spaces, we provide a comparison with the other known versions of Weiss calculus
analogous to the comparisons of calculi of the second named author, and
classify certain stably trivial quaternion vector bundles over finite cell
complexes in a range, using elementary results on convergence of Weiss calculi.Comment: 30 page
Peter Weiss och minnesmaskinen: Motståndets estetik
Analysis of the novel Die Ästhetik des Widerstands by Swedish/German author Peter Weiss. The aim of the analysis is to trace the views of film art that the author presents in this novel. The conclusion is that Weiss expresses explicit views on film art and cinematography, but also that there are implicit patterns in the structure of the narrative that can be explained as a cinematic imagination
Automatic Compilation from High-Level Biologically-Oriented Programming Language to Genetic Regulatory Networks
Background
The field of synthetic biology promises to revolutionize our ability to engineer biological systems, providing important benefits for a variety of applications. Recent advances in DNA synthesis and automated DNA assembly technologies suggest that it is now possible to construct synthetic systems of significant complexity. However, while a variety of novel genetic devices and small engineered gene networks have been successfully demonstrated, the regulatory complexity of synthetic systems that have been reported recently has somewhat plateaued due to a variety of factors, including the complexity of biology itself and the lag in our ability to design and optimize sophisticated biological circuitry.
Methodology/Principal Findings
To address the gap between DNA synthesis and circuit design capabilities, we present a platform that enables synthetic biologists to express desired behavior using a convenient high-level biologically-oriented programming language, Proto. The high level specification is compiled, using a regulatory motif based mechanism, to a gene network, optimized, and then converted to a computational simulation for numerical verification. Through several example programs we illustrate the automated process of biological system design with our platform, and show that our compiler optimizations can yield significant reductions in the number of genes () and latency of the optimized engineered gene networks.
Conclusions/Significance
Our platform provides a convenient and accessible tool for the automated design of sophisticated synthetic biological systems, bridging an important gap between DNA synthesis and circuit design capabilities. Our platform is user-friendly and features biologically relevant compiler optimizations, providing an important foundation for the development of sophisticated biological systems.National Institutes of Health (U.S.) (Grant # 7R01GM74712-5)United States. Defense Advanced Research Projects Agency (contract HR0011-10-C-0168)National Science Foundation (U.S.) (NSF CAREER award 0968682)BBN Technologie
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