94,452 research outputs found
Libro Rojo de Peces Dulceacuícolas de Colombia (2012)
No full textEn el marco del Plan Operativo Anual (2010 – 2011 - 2012) del Programa de Biología de la Conservación y Uso de la Biodiversidad del Instituto de Investigación de Recursos Biológicos Alexander von Humboldt, se llevó a cabo la actualización del Libro Rojo de peces dulceacuícolas de Colombia o proceso de evaluación del riesgo de extinción y evolución del estado de conservación de las especies de peces dulceacuícolas, como también es conocido. Esta iniciativa se llevó a cabo con el aval del Ministerio de Ambiente, Vivienda y Desarrollo Territorial – MAVT (hoy Ministerio de Ambiente y Desarrollo Sostenible – MADS) y la participación del Instituto de Ciencias Naturales de la Universidad Nacional de Colombia, WWF Colombia, y la Universidad de Manizales. En este proceso contribuyeron más de 50
investigadores, vinculados a unas 30 instituciones académicas, gubernamentales y no gubernamentales.Bogotá, D. C
Libro rojo de peces dulceacuícolas de Colombia (2012)
No full textEn el marco del Plan Operativo Anual (2010 – 2011 - 2012) del Programa de Biología de la Conservación y Uso de la Biodiversidad del Instituto de Investigación de Recursos Biológicos Alexander von Humboldt, se llevó a cabo la actualización del Libro Rojo de peces dulceacuícolas de Colombia o proceso de evaluación del riesgo de extinción y evolución del estado de conservación de las especies de peces dulceacuícolas, como también es conocido. Esta iniciativa se llevó a cabo con el aval del Ministerio de Ambiente, Vivienda y Desarrollo Territorial – MAVT (hoy Ministerio de Ambiente y Desarrollo Sostenible – MADS) y la participación del Instituto de Ciencias Naturales de la Universidad Nacional de Colombia, WWF Colombia, y la Universidad de Manizales. En este proceso contribuyeron más de 50
investigadores, vinculados a unas 30 instituciones académicas, gubernamentales y no gubernamentales.Bogotá, D. C
Maria F. Gravina Telechea, Lázaro vuela rojo
No full textPailler Claire. Maria F. Gravina Telechea, Lázaro vuela rojo. In: Cahiers du monde hispanique et luso-brésilien, n°35, 1980. pp. 198-200
C.F. ROJO & SONS PTY. LTD.
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/64239Ledgers 1881-1949; cash books 1888-1963; day books and journals 1882-1953; time books 1946-1950; wage books 1933-1961; cash reimbursements.112345
Acquisition: [1965.0022] "C.F. ROJO & SONS PTY. LTD.
Pseudo-glicodendrimeri come inibitori di DC-SIGN
No full textDC-SIGN (Dendritic Cell-Specific ICAM-3 Grabbing Non-Integrin) è un recettore delle cellule dendritiche in grado di riconoscere glicoproteine altamente mannosilate presenti sulla superficie di un ampio spettro di patogeni. Studi su sugar microarrays hanno infatti dimostrato che il recettore riconosce in modo selettivo e con buona affinita’ diversi oligosaccaridi del mannosio e alcuni oligosaccaridi fucosilati della serie Lewis.1,2 Si ipotizza che tale interazione giochi un ruolo importante nel processo infettivo, per esempio, HIV usa proprio DC-SIGN per infiltrarsi nel sistema immunitario dell’ospite.3
Il gruppo di ricerca di Siviglia, diretto dal Dr. Rojo, ha preparato dei polimeri a struttura dendritica polifunzionalizzati con mannosio:4 gli studi di affinità sul dendrimero recante 32 copie dello zucchero hanno mostrato che questo riesce ad inibire (IC50 337nM) l’interazione tra DC-SIGN e un modello virale pseudo-Ebola.
Risultati così positivi hanno suscitato il nostro interesse verso potenziali applicazioni di questi sistemi come composti antivirali,5,6 tenendo però conto del fatto che, quando utilizzati in vivo, essi sono riconosciuti e degradati dalle glicosilasi. Per ovviare a questo inconveniente si è pensato di ottenere strutture piu’ stabili inserendo nei costrutti dei mimici che mantengano la capacità di binding al recettore.
Il nostro gruppo di ricerca ha una vasta esperienza nella preparazione di pseudo-oligosaccaridi7-9 e ha dimostrato come questi possano interagire con le lectine pur avendo velocità di degradazione inferiore rispetto agli oligosaccaridi naturali. Uno di questi composti è lo pseudo–mannobioside 1 che mima il Man-α-1,2-Man10 e può essere considerato, insieme ad altri, un buon candidato da legare allo scaffold multivalente e per testarne l’affinità a DC-SIGN.
La sintesi dei dendrimeri poli pseudo-glicosilati e’ stata realizzata secondo lo schema riportato, ottenendo un loading medio di 26 copie dello pseudo-mannobioside 1. I test biologici sono stati effettuati con un sensore SPR funzionalizzato con DC-SIGN 11-13 e hanno mostrato che, nonostante il loading inferiore, l’attività di 2 è 6.5 volte maggiore rispetto a quella del dendrimero che contiene 32 unita’ di mannosio.
I risultati di questi studi preliminari sono molto incoraggianti per lo sviluppo di nuovi antivirali che hanno DC-SIGN come target molecolare
Evaluating management regimes for European beech forests using dynamic programming
No full textCITATION: Torres-Rojo, J.M., Vilcko, F. & Von Gadow, K. 2014. Evaluating management regimes for European beech forests using dynamic programming. Forest Systems, 23(3):470-482, doi:10.5424/fs/2014233-05296.The original publication is available at http://revistas.inia.es/index.php/fs/indexAim of study: This contribution describes a systematic search method for identifying optimum thinning regimes for beech forests (Fagus sylvatica L.) by using a combination of optimization heuristics and a simple whole stand growth prediction model.
Area of study: Data to build the model come from standard and management forest inventories as well as yield tables from the Northern and Western part of Germany and from southern and central Denmark. Material and methods: Growth projections are made from equations to project basal area and top height. The remaining stand variables are recovered from additional equations fitted from forest inventory data or acquired from other authors. Mortality is estimated through an algorithm based on the maximum density line. The optimization routine uses a two-state dynamic programming model. Thinning type is defined by the NG index, which describes the ratio of the proportion of removed trees and basal area with respect to the same proportion before thinning.
Main results: Growth equations fitted from inventory data show high goodness of fit with R2 values larger than 0.85 and high significance levels for the parameter estimates. The mortality algorithm converges quickly providing mortality estimates within the expected range.
Research highlights: The combination of a simple growth and yield model within a Dynamic Programming framework in conjunction with NG values as indicators of thinning type yield good estimates of practical thinning schedules compared to thinning recommendations provided by diverse authors.http://revistas.inia.es/index.php/fs/article/view/5296Publisher's versio
HERA data and DGLAP evolution: Theory and phenomenology
No full textWe examine critically the evidence for deviations from next-to-leading order perturbative DGLAP evolution in HERA data. We briefly review the status of perturbative small-x resummation and of global determinations of parton distributions. We show that the geometric scaling properties of HERA data are consistent with DGLAP evolution, which is also strongly supported by the double asymptotic scaling properties of the data. However, backward-evolution of parton distributions into the low x, low Q2 region does show evidence of deviations between the observed behaviour and the next-to-leading order predictions. These deviations cannot be explained by missing next-to-next-to-leading order perturbative terms, and are consistent with perturbative small-x resummation. © 2010 Elsevier B.V
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
- …
