5 research outputs found

    Additional file 2 of In-silico and in-vitro studies on the efficacy of mangiferin against colorectal cancer

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    Additional file 2: Table S1. Grid Map of Target Proteins. Table S2. Area and volume predicted by CASTp for each protein (as active sites). Table S3. 2D-QSAR models for Xanthone derivatives. Table S4. Pearson correlation matrix of selected descriptors along with pIC50 value. Table S5. Toxicity Classes

    Additional file 1 of In-silico and in-vitro studies on the efficacy of mangiferin against colorectal cancer

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    Additional file 1: Figure S1. Binding of Rofecoxib inhibitor with chain A of COX-2. Note: binding was present in the crystal structure of COX-2. Figure S2. Binding of Rofecoxib inhibitor with chain B of COX-2. Note: binding was present in the crystal structure of COX-2. Figure S3. (a-m). Pose comparisons of along with bounded RCX ligand for pose comparison. Figure S4. Symbols used to show Protein–Ligand Interaction (LigPlus Software). Figure S5. Protein–Ligand Interaction of RCX ligand with COX-2 chain A. Figure S6. Protein–Ligand Interaction of Pose 01 of molecular docking of Mangiferin at the site of RCX inhibitor ligand. Figure S7. Protein–Ligand Interaction of Pose 02 of molecular docking of Mangiferin at the site of RCX inhibitor ligand. Figure S8. Protein–Ligand Interaction of Pose 03 of molecular docking of Mangiferin at the site of RCX inhibitor ligand. Figure S9. Protein–Ligand Interaction of Pose 04 of molecular docking of Mangiferin at the site of RCX inhibitor ligand. Figure S10. Protein–Ligand Interaction of Pose 05 of molecular docking of Mangiferin at the site of RCX inhibitor ligand. Figure S11. Protein–Ligand Interaction of RCX ligand with COX-2 chain B. Figure S12. Protein–Ligand Interaction of Pose 01 of molecular docking of Mangiferin at the site of RCX inhibitor ligand. Figure S13. Protein–Ligand Interaction of Pose 02 of molecular docking of Mangiferin at the site of RCX inhibitor ligand

    Abstracts of National Conference on Biological, Biochemical, Biomedical, Bioenergy, and Environmental Biotechnology

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    This book contains the abstracts of the papers presented at the National Conference on Biological, Biochemical, Biomedical, Bioenergy, and Environmental Biotechnology (NCB4EBT-2021) Organized by the Department of Biotechnology, National Institute of Technology Warangal, India held on 29–30 January 2021. This conference is the first of its kind organized by NIT-W which covered an array of interesting topics in biotechnology. This makes it a bit special as it brings together researchers from different disciplines of biotechnology, which in turn will also open new research and cooperation fields for them. Conference Title: National Conference on Biological, Biochemical, Biomedical, Bioenergy, and Environmental BiotechnologyConference Acronym: NCB4EBT-2021Conference Date: 29–30 January 2021Conference Location: Online (Virtual Mode)Conference Organizer: Department of Biotechnology, National Institute of Technology Warangal, Indi
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