131,711 research outputs found
The role of six biomarkers in diagnosis of hemophilic arthropathy: review of the literature
No full textThe aim of our narrative review of the literature is to identify the role of six important biomarkers: synovial fluid thrombomodulin, fibroblast-like synoviocytes, synovial tissue growth factor , vascular endothelial growth factor in synovium and peripheral blood, urinary C-terminal telopeptide of type II collagen, and synovial fluid tumor necrosis factor alpha. These urinary, serum and synovial biomarkers illustrated should be evaluated in patients with hemophilic arthropathy for early diagnosis of hemophilic arthropathy, because they have important implications in the development of arthrofibrosis, altered inflammatory response and bleeding. Moreover, better knowledge of their biological activity is important to identify possible new biological treatment options
Consensus recommendations for the use of FEIBA<sup>®</sup> in haemophilia A patients with inhibitors undergoing elective orthopaedic and non-orthopaedic surgery
No full textSummary: A growing number of publications have described the efficacy and safety of FEIBA as a first-line haemostatic agent for surgical procedures in haemophilia A patients with high-responding FVIII inhibitors. The aim of this study was to provide practical guidance on patient management and selection and also to communicate a standardized approach to the dosing and monitoring of FEIBA during and after surgery. A consensus group was convened with the aims of (i) providing an overview of the efficacy and safety of FEIBA in surgery; (ii) sharing best practice; (iii) developing recommendations based on the outcome of (i) and (ii). To date there have been 17 publications reporting on the use of FEIBA in over 210 major and minor orthopaedic and non-orthopaedic surgical procedures. Haemostatic outcome was rated as 'excellent' or 'good' in 78-100% of major cases. The reporting of thromboembolic complications or anamnestic response to FEIBA was very rare. Key to the success of FEIBA as haemostatic cover in surgery is to utilize the preplanning phase to prepare the patient both for surgery and also for rehabilitation. Haemostatic control with FEIBA should be continued for an adequate period postoperatively to support wound healing and to cover what can in some patients be an extended period of physiotherapy. Published data have demonstrated that FEIBA can provide adequate, well tolerated, peri and postoperative haemostatic cover for a variety of major and minor surgical procedures in patients with haemophilia A. The consensus recommendations provide a standardized approach to the dosing and monitoring of FEIBA.</p
Pain Care Management in Rare Diseases
No full text: In this Special Issue on "Musculoskeletal Pain Care and Management in Rare Disease", it is essential to make it clear that, while specialists in rare diseases (RDs) are often very knowledgeable about the management of the specific diseases in which they are experts, primary care physicians and other physicians who are not experts in a given disease often have very little contact with the patients who experience it [...]
DSC evaluation of thermoxidative decomposition of extra virgin olive oil: effect of microwave and conventional heating
No full textThe aim of this work was to evaluate DSC thermal properties of extra virgin olive oil subjected to microwave and thermal heating. Fresh extra virgin olive oil was stored in dark bottles under nitrogen at room temperature before analysis. Sample were placed in a 250 ml open flask and either heated in an electric oven (with air convection) at 180°C for 30, 90, 120, 180, 360, 900 and 1440 min, or microwaved (at 2450 MHz, 0.72 kW) for 3, 6, 9, 12, 15 and 20 min. All samples were cooled at room temperature in the dark to 30°C and then analyzed. Thermograms were obtained by means of DSC, by cooling from 30 to -80°C at 2°C/min, holding 3 min at -80°C and heating from -80 to 30°C at 2°C/min. Enthalpy (H, J/g), onset (Ton), and offset (Toff) temperatures of the transitions were obtained.
Lipid crystallization Ton of fresh extra virgin olive oil was at -11°C and developed over a 35–40 degrees range. Two well defined events (minor, peaking at -16 and major peaking at -40°C) were distinguishable. Heating thermograms of fresh sample showed a minor exothermic peak and successively a major endothermic event occurring over the -18°C/12°C temperature range, with the presence of a major endothermic peak (-5°C) and a small shoulder at 8°C.
Enthalpy of both crystallization and melting transition significantly decreased in all samples with increasing length of heating treatment; this effect was more pronounced for the microwaved sample. Crystallization peak line-shape dramatically changed with increasing heating time. The major crystallization peak decreased in height, and the transition spanned over a larger temperature range, because of a significant shift of Toff towards lower temperatures. Crystallization Ton remain constant in conventionally heated samples, whereas it significantly shifted towards higher temperature in samples microwaved for at least 12 min. Melting line-shapes also dramatically changed; in fact, the major endothermic peak flattened, decreased in height, and spanned over a larger temperature range, while the minor endothermic peak disappeared in the longest treated samples. An additional endothermic peak also appeared at lower temperature after 20 and 900 min of microwave and conventional treatment, respectively. Ton of the heating transition significantly shifted towards lower temperatures at increasing treatment time.
In conclusion, changes in all thermal properties were already evident in microwaved samples after 9 minutes of treatment, whereas similar values were reached after 360 min of air convection heating
HJHS 2.1 and HEAD-US assessment in the hemophilic joints: How do their findings compare?
No full text: In hemophilic patients methods are needed to better diagnose joint damage early, so that treatments can be adjusted to slow the progression of hemophilic arthropathy. The aim of this study is to investigate the relationship between the Hemophilia Joint Health Score version 2.1 (HJHS 2.1) and hemophilia early arthropathy detection with ultrasound (HEAD-US) scales, as well as each of their individual items, to better understand the value each provides on the joint condition of patients with hemophilia. The study included data from patients with hemophilia older than 16 years of age, who attended a routine check-up. HJHS 2.1 and HEAD-US assessments were performed on the elbows, knees and ankles. We studied the correlations and agreements between the two scales and analyzed the relationship between the various items of the HJHS 2.1 (inflammation, duration, atrophy, crepitation, flexion deficit, extension deficit, pain, strength, gait) and HEAD-US (synovitis, cartilage and bone). The study included 203 joints from 66 patients with hemophilia (mean age, 34 years). We found a good correlation between the two scales (r = 0.717). However, HJHS 2.1 revealed only 54% of the cases with synovitis and 75% of the cases with osteochondral damage. HEAD-US detected several relevant physical and functional aspects in less than 53% of the cases. HJHS 2.1 and HEAD-US provide complementary data on joint disease in adults with hemophilia; both assessments should therefore, be made available. HEAD-US presented the added value of detecting early joint changes (synovitis and osteochondral damage), while HJHS 2.1 showed the added value of detecting relevant physical and functional changes
Bellucia grossularioides (L.) Triana from Colombia collected by L. Ramos, E. Álvarez, J. Cabezas, J. Rodriguez & C. Ibañez #33
No full textFile Name: TOLI-25022-RAN-01-15-C-33.jpg
CÓDIGO FOTO: TOLI-25022-RAN-01-15-C-33-
Fotografía: SI
Nº TOLI: TOLI-25022
PARCELA: RAN-01
CÓDIGO: 15-C-33
Nº COLECTA: 33
NUEVOS COLECTORES: Laura Isabel Ramos
COLECTORES: L. Ramos, E. Álvarez, J. Cabezas, J. Rodriguez & C. Ibañez
Nº MUESTRAS MONTADAS: 1
Homologación: Homologado
Nueva fecha del evento : 20/12/2018.
Fecha del evento: 27/11/2018.
Proyecto : Recursos Botánicos Disponibles en Línea (BRAVO) para la flora Colombiana
Hábitat: Bosque húmedo tropical (bh-T)
Continente: SA
Pais: Colombia
Estado/Provincia: Meta
Municipio: Puerto López
Centro poblado / Cabecera municipal: La Serranía
Localidad: Reserva Natural El Amparo
Elevación minima en metros: 200
Elevación maxima en metros: 250
Latitud: 4.020
Longitud original: -72.600
datum geodésico: WGS 84
Latitud decimal: 4.020
Longitud decimal: -72.600
Identificado por: Humberto Mendoza
Fecha de identificación: 18/01/2019.
Nombre cientifico: Bellucia grossularioides (L.) Triana
Reino: Plantae
Filo: Magnoliophyta
Clase: Equisetopsida
Orden: Myrtales
Familia nueva: Melastomataceae
Género nuevo: Bellucia
especie nueva: grossularioides
Autoría del nombre científico: (L.) Triana
: Melastomataceae
genero herbario: Bellucia
especie herbario: grossularioides
Especie de herbario para TNRS: Bellucia grossularioides
Especie corregida herbario y desde TNRS: Bellucia grossularioides
Familia corregida desde TNRS: Melastomataceae
: 405
Licania sp. 5 from Colombia collected by J. Cabezas, E. Álvarez, L. Ramos, J. Rodriguez, C. Ibañez #1211
No full textFile Name: TOLI-24014-SOC-01-02-C-138.jpg
CÓDIGO FOTO: TOLI-24014-SOC-01-02-C-138-
Fotografía: SI
Nº TOLI: TOLI-24014
PARCELA: SOC-01
CÓDIGO: 02-C-138
Nº COLECTA: 1211
NUEVOS COLECTORES: Jaime Andrés Cabezas
COLECTORES: J. Cabezas, E. Álvarez, L. Ramos, J. Rodriguez, C. Ibañez
Nº MUESTRAS MONTADAS: 1
Homologación: Homologado
Nueva fecha del evento : 21/12/2018.
Fecha del evento: 27/11/2018.
Proyecto : Recursos Botánicos Disponibles en Línea (BRAVO) para la flora Colombiana
Hábitat: Bosque húmedo tropical (bh-T)
Continente: SA
Pais: Colombia
Estado/Provincia: Meta
Municipio: Puerto López
Centro poblado / Cabecera municipal: La Serranía
Localidad: Reserva Natural El Amparo
Elevación minima en metros: 200
Elevación maxima en metros: 250
Latitud: 4.020
Longitud original: -72.600
datum geodésico: WGS 84
Latitud decimal: 4.020
Longitud decimal: -72.600
Identificado por: Zoe Goodwin
Fecha de identificación: 25/01/2019.
Familia antigua: Chrysobalanaceae
Especie antigua: Licania sp.
Nombre cientifico: Licania sp. 5
Reino: Plantae
Filo: Magnoliophyta
Clase: Equisetopsida
Orden: Malpighiales
Familia nueva: Chrysobalanaceae
Género nuevo: Licania
especie nueva: sp.
: Chrysobalanaceae
genero herbario: Licania
especie herbario: sp.
Especie de herbario para TNRS: Licania sp.
Especie corregida herbario y desde TNRS: Licania indet
Familia corregida desde TNRS: Chrysobalanaceae
: 309
NN from Colombia collected by L. Ramos, E. Álvarez, J. Cabezas, J. Rodriguez & C. Ibañez #66
No full textFile Name: TOLI-24909-RAN-01-21-P-66.jpg
CÓDIGO FOTO: TOLI-24909-RAN-01-21-P-66-
Fotografía: SI
Nº TOLI: TOLI-24909
PARCELA: RAN-01
CÓDIGO: 21-P-66
Nº COLECTA: 66
NUEVOS COLECTORES: Laura Isabel Ramos
COLECTORES: L. Ramos, E. Álvarez, J. Cabezas, J. Rodriguez & C. Ibañez
Nº MUESTRAS MONTADAS: 1
Homologación: No homologado
Nueva fecha del evento : 20/12/2018.
Fecha del evento: 15/05/2014.
Proyecto : Recursos Botánicos Disponibles en Línea (BRAVO) para la flora Colombiana
Hábitat: Bosque húmedo tropical (bh-T)
Continente: SA
Pais: Colombia
Estado/Provincia: Meta
Municipio: Puerto López
Centro poblado / Cabecera municipal: La Serranía
Localidad: Reserva Natural El Amparo
Elevación minima en metros: 200
Elevación maxima en metros: 250
Latitud: 4.020
Longitud original: -72.600
datum geodésico: WGS 84
Latitud decimal: 4.020
Longitud decimal: -72.600
Nombre cientifico: NN
Reino: Plantae
Filo: Magnoliophyta
Clase: Equisetopsida
Orden: Gentianales
Familia nueva: Apocynaceae
Género nuevo: NN
: Apocynaceae
genero herbario: NN
Especie de herbario para TNRS: NN
Especie corregida herbario y desde TNRS: Indet indet
Familia corregida desde TNRS: Apocynaceae
: 394
Ficus sp. from Colombia collected by J. Cabezas, E. Álvarez, L. Ramos, J. Rodriguez, C. Ibañez #1207
No full textFile Name: TOLI-24910-SOC-01-21-C-134.jpg
CÓDIGO FOTO: TOLI-24910-SOC-01-21-C-134-
Fotografía: SI
Nº TOLI: TOLI-24910
PARCELA: SOC-01
CÓDIGO: 21-C-134
Nº COLECTA: 1207
NUEVOS COLECTORES: Jaime Andrés Cabezas
COLECTORES: J. Cabezas, E. Álvarez, L. Ramos, J. Rodriguez, C. Ibañez
Nº MUESTRAS MONTADAS: 1
Homologación: No homologado
Nueva fecha del evento : 21/12/2018.
Fecha del evento: 27/11/2018.
Proyecto : Recursos Botánicos Disponibles en Línea (BRAVO) para la flora Colombiana
Hábitat: Bosque húmedo tropical (bh-T)
Continente: SA
Pais: Colombia
Estado/Provincia: Meta
Municipio: Puerto López
Centro poblado / Cabecera municipal: La Serranía
Localidad: Reserva Natural El Amparo
Elevación minima en metros: 200
Elevación maxima en metros: 250
Latitud: 4.020
Longitud original: -72.600
datum geodésico: WGS 84
Latitud decimal: 4.020
Longitud decimal: -72.600
Nombre cientifico: Ficus sp.
Reino: Plantae
Filo: Magnoliophyta
Clase: Equisetopsida
Orden: Rosales
Familia nueva: Moraceae
Género nuevo: Ficus
especie nueva: sp.
: Moraceae
genero herbario: Ficus
especie herbario: sp.
Especie de herbario para TNRS: Ficus sp.
Especie corregida herbario y desde TNRS: Ficus indet
Familia corregida desde TNRS: Moraceae
: 394
NN from Colombia collected by J. Cabezas, E. Álvarez, L. Ramos, J. Rodriguez, C. Ibañez #1224
No full textFile Name: TOLI-24021-SOC-01-1-A-151.jpg
CÓDIGO FOTO: TOLI-24021-SOC-01-1-A-151-
Fotografía: SI
Nº TOLI: TOLI-24021
PARCELA: SOC-01
CÓDIGO: 1-A-151
Nº COLECTA: 1224
NUEVOS COLECTORES: Jaime Andrés Cabezas
COLECTORES: J. Cabezas, E. Álvarez, L. Ramos, J. Rodriguez, C. Ibañez
Nº MUESTRAS MONTADAS: 1
Homologación: No homologado
Nueva fecha del evento : 21/12/2018.
Fecha del evento: 28/11/2018.
Proyecto : Recursos Botánicos Disponibles en Línea (BRAVO) para la flora Colombiana
Hábitat: Bosque húmedo tropical (bh-T)
Continente: SA
Pais: Colombia
Estado/Provincia: Meta
Municipio: Puerto López
Centro poblado / Cabecera municipal: La Serranía
Localidad: Reserva Natural El Amparo
Elevación minima en metros: 200
Elevación maxima en metros: 250
Latitud: 4.020
Longitud original: -72.600
datum geodésico: WGS 84
Latitud decimal: 4.020
Longitud decimal: -72.600
Nombre cientifico: NN
Reino: Plantae
Filo: Magnoliophyta
Clase: Equisetopsida
Orden: Myrtales
Familia nueva: Myrtaceae
Género nuevo: NN
: Myrtaceae
genero herbario: NN
Especie de herbario para TNRS: NN
Especie corregida herbario y desde TNRS: Indet indet
Familia corregida desde TNRS: Myrtaceae
: 310
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