369 research outputs found
Supplementary code, raw data and figure plots from "Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells"
No full textSupplementary code, raw data and figure plots from the paper:"Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells"Ivar Noordstra, Cyntha M. van den Berg, Fransje W. J. Boot, Eugene A. Katrukha, Ka Lou Yu, Roderick P. Tas, Sybren Portegies, Bastiaan J. Viergever, Esther de Graaff, Casper C. Hoogenraad, Eelco J. P. de Koning, Françoise Carlotti, Lukas C. Kapitein, Anna Akhmanova </p
The development and validation of a Televisitation Attitude Scale (TAS).
No full textThe 12 item Televisitation Attitude Scale (TAS) was developed in this study using the method of factor analysis. The prototype Televisitation Attitude Scale (TAS) was administered to UNBC students (N=204) in an on-line format. Kaiser-Meyer-Olkin’s (KMO) test was .900 and Barlett’s test was χ² (66) = 1198.500, p<.001, confirming the validity of the obtained data. The Chronbach’s alpha test reliability for the final TAS was .91. It was found that the students’ attitudes toward televisitation were one-dimensional (Evaluation dimension) and had a positive tendency (M = 1.29 on -3 +3 scale). Independent sample t-tests (p ≲ .05) found significant differences in attitudes toward televisitation among subpopulations of UNBC students distinguished by gender, presence of children, and place of birth. TAS and its methodology can help researchers and televisitation investors to predict with some degree of accuracy whether a support person would televisit a patient in a hospital or a nursing home.The original print copy of this thesis may be available here: http://wizard.unbc.ca/record=b175483
Table_1_A Comparison of Bevacizumab Plus TAS-102 and TAS-102 Monotherapy for Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.docx
No full textBackgroundsAs a new oral chemotherapy drug, TAS-102 is currently recommended as the third-line treatment for metastatic colorectal cancer (mCRC). Recently, studies have reported the efficacy of TAS-102 combined with bevacizumab in colon cancer patients after standard treatment fails. Here, we evaluated the efficacy and safety of TAS-102 combined with bevacizumab versus TAS-102 as a single agent by a systematic review and a meta-analysis.MethodsPubMed, Web of Science and Cochrane libraries were searched. Studies involving bevacizumab combined with TAS-102 in mCRC were included. Study characteristics (author, year of publication, country et al.), efficacy (disease control rate(DCR), progression-free survival(PFS), overall survival(OS)) and adverse effects were extract from studies. Forest plots were created based on Cox model analysis.ResultsAfter screening 550 studies, a total of 3 studies were included, which compared the safety and effectiveness of TAS-102 with or without bevacizumab. Analysis based on Cox regression showed that the combined treatment group had advantages in 6-month (OR= 2.93, 95% CI: 1.72 to 5.00, PConclusionBevacizumab combined with TAS-102 could improve the prognosis of patients with mCRC who have failed standard treatment. In terms of side effects, the addition of bevacizumab did not increase serious adverse reactions, but the occurrence of thrombocytopenia was worth noting.</p
Image_1_A Comparison of Bevacizumab Plus TAS-102 and TAS-102 Monotherapy for Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.tif
No full textBackgroundsAs a new oral chemotherapy drug, TAS-102 is currently recommended as the third-line treatment for metastatic colorectal cancer (mCRC). Recently, studies have reported the efficacy of TAS-102 combined with bevacizumab in colon cancer patients after standard treatment fails. Here, we evaluated the efficacy and safety of TAS-102 combined with bevacizumab versus TAS-102 as a single agent by a systematic review and a meta-analysis.MethodsPubMed, Web of Science and Cochrane libraries were searched. Studies involving bevacizumab combined with TAS-102 in mCRC were included. Study characteristics (author, year of publication, country et al.), efficacy (disease control rate(DCR), progression-free survival(PFS), overall survival(OS)) and adverse effects were extract from studies. Forest plots were created based on Cox model analysis.ResultsAfter screening 550 studies, a total of 3 studies were included, which compared the safety and effectiveness of TAS-102 with or without bevacizumab. Analysis based on Cox regression showed that the combined treatment group had advantages in 6-month (OR= 2.93, 95% CI: 1.72 to 5.00, PConclusionBevacizumab combined with TAS-102 could improve the prognosis of patients with mCRC who have failed standard treatment. In terms of side effects, the addition of bevacizumab did not increase serious adverse reactions, but the occurrence of thrombocytopenia was worth noting.</p
Recensiones [Revista de Historia Económica Año X Otoño 1992 n. 3 pp. 519-548]
No full textEditada en la Universidad Carlos IIIFranco Amatori y Bruno Bezza. Montecatini 1888-1966. Capitoli di storia di una grande impresa. (Por Núria Puig).-- Dudley Baines. Emigration from Europe, 1815-1930. (Por Blanca Sánchez Alonso).-- Roderick Floud, Kenneth Wachter y Annabel Gregory. Height, Health and History. Nutritional Status in the United Kingdom, 1750-1980. (Por José Miguel Martínez Carrión).-- G. Goertz. The World Chemical Industry around 1910: a Comparative Analysis by Branch and Country. (Por Núria Puig).-- José Luis García Delgado, ed.. Las ciudades en la modernización de España. Los decenios interseculares. VIII Coloquio de Historia Contemporánea de España dirigido por Manuel Tuñón de Lara. (Por Luis Garrido González).-- Charles P. Kindleberger. Manias, Panics and Crashes. A History of Financial Crisis. (Por J. Ignacio Peña).-- Carlos Alberto Mayo. Los Betlemitas en Buenos Aires: Convento, Economía y Sociedad (1748-1822). (Por Carlos Newland).-- Hilda Sábato. Agrarian Capitalism and the World Market: Buenos Aires in the Pastoral Age, 1840-1890. (Por Julio E. Revilla).-- Gabriel Tortella, ed.. Educación y Desarrollo Económico desde la Revolución Industrial. (Por Cecilia Albert)Publicad
Flinders Island, Tas, 1987 (P524), radiometric line data, AWAGS levelled
No full textMaintenance and Update Frequency: notPlannedStatement: This Flinders Island, Tas, 1987 (P524), radiometric line data, AWAGS levelled is an airborne-derived radiometric data for the Flinders Island, Tas, 1987. The data was acquired under the project No. 524 for the geological survey of TAS. A total of 3445 line-kilometres of data at a line spacing of 1500m were acquired during this survey. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data (Milligan et al., 2009). This survey data is essentially levelled to AWAGS. Noise-adjusted singular value decomposition (NASVD) has been applied to the data. NASVD is a spectral component analysis procedure for the removal of noise from gamma-ray spectra. Details of the specifications of individual airborne surveys can be found in the Fourteenth Edition of the Index of Airborne Geophysical Surveys (Percival, 2014). This Index is also available online at http://pid.geoscience.gov.au/dataset/79134.
References:
Milligan, P.R., Minty, B.R.S., Richardson, M. & Franklin, R., 2009. The Australia-wide Airborne Geophysical Survey accurate continental magnetic coverage. Preview, No. 138, p. 1-128,
Percival, P.J., 2014. Index of airborne geophysical surveys (Fourteenth Edition).The radiometric, or gamma-ray spectrometric method, measures the natural variations in the gamma-rays detected near the Earth's surface as the result of the natural radioactive decay of potassium (K), uranium (U) and thorium (Th). The data collected are processed via standard methods to ensure the response recorded is that due only to the rocks in the ground. The results produce datasets that can be interpreted to reveal the geological structure of the sub-surface. The processed data is checked for quality by GA geophysicists to ensure that the final data released by GA are fit-for-purpose.<br/> This Flinders Island, Tas, 1987 (P524), radiometric line data, AWAGS levelled were acquired in 1987 by the TAS Government, and consisted of 3445 line-kilometres of data at 1500m line spacing and 150m terrain clearance. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data. This survey data is essentially levelled to AWAGS
NETGOLD - Pipers River, TAS, 1993 (P783), radiometric line data, AWAGS levelled
No full textMaintenance and Update Frequency: notPlannedStatement: This NETGOLD - Pipers River, TAS, 1993 (P783), radiometric line data, AWAGS levelled is an airborne-derived radiometric data for the NETGOLD - Fingal, Pipers River, Mt.Horror, TAS, 1993. The data was acquired under the project No. 783 for the geological survey of TAS. A total of 16797 line-kilometres of data at a line spacing of 200m were acquired during this survey. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data (Milligan et al., 2009). This survey data is essentially levelled to AWAGS. Noise-adjusted singular value decomposition (NASVD) has been applied to the data. NASVD is a spectral component analysis procedure for the removal of noise from gamma-ray spectra. Details of the specifications of individual airborne surveys can be found in the Fourteenth Edition of the Index of Airborne Geophysical Surveys (Percival, 2014). This Index is also available online at http://pid.geoscience.gov.au/dataset/79134.
References:
Milligan, P.R., Minty, B.R.S., Richardson, M. & Franklin, R., 2009. The Australia-wide Airborne Geophysical Survey accurate continental magnetic coverage. Preview, No. 138, p. 1-128,
Percival, P.J., 2014. Index of airborne geophysical surveys (Fourteenth Edition).The radiometric, or gamma-ray spectrometric method, measures the natural variations in the gamma-rays detected near the Earth's surface as the result of the natural radioactive decay of potassium (K), uranium (U) and thorium (Th). The data collected are processed via standard methods to ensure the response recorded is that due only to the rocks in the ground. The results produce datasets that can be interpreted to reveal the geological structure of the sub-surface. The processed data is checked for quality by GA geophysicists to ensure that the final data released by GA are fit-for-purpose.<br/> This NETGOLD - Pipers River, TAS, 1993 (P783), radiometric line data, AWAGS levelled were acquired in 1993 by the TAS Government, and consisted of 16797 line-kilometres of data at 200m line spacing and 80m terrain clearance. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data. This survey data is essentially levelled to AWAGS
NETGOLD - Mt Horror, TAS, 1993 (P783), magnetic line data, AWAGS levelled
No full textMaintenance and Update Frequency: notPlannedStatement: This NETGOLD - Mt Horror, TAS, 1993 (P783), magnetic line data, AWAGS levelled is an airborne-derived magnetic line dataset for the NETGOLD - Fingal, Pipers River, Mt.Horror, TAS, 1993 survey. The data was acquired under the project No. 783 for the geological survey of TAS. A total of 16797 line-kilometres of data at a line spacing of 200m and 80m terrain clearance were acquired during this survey. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data (Milligan et al., 2009). This survey data is essentially levelled to AWAGS. Details of the specifications of individual airborne surveys can be found in the Fourteenth Edition of the Index of Airborne Geophysical Surveys (Percival, 2014). This Index is also available online at http://pid.geoscience.gov.au/dataset/79134.
References:
Milligan, P.R., Minty, B.R.S., Richardson, M. & Franklin, R., 2009. The Australia-wide Airborne Geophysical Survey accurate continental magnetic coverage. Preview, No. 138, p. 1-128,
Percival, P.J., 2014. Index of airborne geophysical surveys (Fourteenth Edition).Total magnetic intensity (TMI) data measures variations in the intensity of the Earth's magnetic field caused by the contrasting content of rock-forming minerals in the Earth crust. Magnetic anomalies can be either positive (field stronger than normal) or negative (field weaker) depending on the susceptibility of the rock. The data are processed via standard methods to ensure the response recorded is that due only to the rocks in the ground. The results produce datasets that can be interpreted to reveal the geological structure of the sub-surface. The processed data is checked for quality by GA geophysicists to ensure that the final data released by GA are fit-for-purpose.<br/> These line dataset from the NETGOLD - Fingal, Pipers River, Mt.Horror, TAS, 1993 survey were acquired in 1993 by the TAS Government, and consisted of 16797 line-kilometres of data at 200m line spacing and 80m terrain clearance. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data. This survey data is essentially levelled to AWAGS
Strathblane and Catamaran, Tas, 1982 (P835), magnetic line data, AWAGS levelled
No full textMaintenance and Update Frequency: notPlannedStatement: This Strathblane and Catamaran, Tas, 1982 (P835), magnetic line data, AWAGS levelled is an airborne-derived magnetic line dataset for the Strathblane and Catamaran, Tas, 1982 survey. The data was acquired under the project No. 835 for the geological survey of TAS. A total of 1511 line-kilometres of data at a line spacing of 500m and 135m terrain clearance were acquired during this survey. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data (Milligan et al., 2009). This survey data is essentially levelled to AWAGS. Details of the specifications of individual airborne surveys can be found in the Fourteenth Edition of the Index of Airborne Geophysical Surveys (Percival, 2014). This Index is also available online at http://pid.geoscience.gov.au/dataset/79134.
References:
Milligan, P.R., Minty, B.R.S., Richardson, M. & Franklin, R., 2009. The Australia-wide Airborne Geophysical Survey accurate continental magnetic coverage. Preview, No. 138, p. 1-128,
Percival, P.J., 2014. Index of airborne geophysical surveys (Fourteenth Edition).Total magnetic intensity (TMI) data measures variations in the intensity of the Earth's magnetic field caused by the contrasting content of rock-forming minerals in the Earth crust. Magnetic anomalies can be either positive (field stronger than normal) or negative (field weaker) depending on the susceptibility of the rock. The data are processed via standard methods to ensure the response recorded is that due only to the rocks in the ground. The results produce datasets that can be interpreted to reveal the geological structure of the sub-surface. The processed data is checked for quality by GA geophysicists to ensure that the final data released by GA are fit-for-purpose.<br/> These line dataset from the Strathblane and Catamaran, Tas, 1982 survey were acquired in 1982 by the TAS Government, and consisted of 1511 line-kilometres of data at 500m line spacing and 135m terrain clearance. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data. This survey data is essentially levelled to AWAGS
Macquarie Harbour and Southwest Tasmania, TAS, 1985 (P629), radiometric line data, AWAGS levelled
No full textMaintenance and Update Frequency: notPlannedStatement: This Macquarie Harbour and Southwest Tasmania, TAS, 1985 (P629), radiometric line data, AWAGS levelled is an airborne-derived radiometric data for the Macquarie Harbour & Southwest Tasmania, TAS, 1985. The data was acquired under the project No. 629 for the geological survey of TAS. A total of 4833 line-kilometres of data at a line spacing of 500m were acquired during this survey. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data (Milligan et al., 2009). This survey data is essentially levelled to AWAGS. Noise-adjusted singular value decomposition (NASVD) has been applied to the data. NASVD is a spectral component analysis procedure for the removal of noise from gamma-ray spectra. Details of the specifications of individual airborne surveys can be found in the Fourteenth Edition of the Index of Airborne Geophysical Surveys (Percival, 2014). This Index is also available online at http://pid.geoscience.gov.au/dataset/79134.
References:
Milligan, P.R., Minty, B.R.S., Richardson, M. & Franklin, R., 2009. The Australia-wide Airborne Geophysical Survey accurate continental magnetic coverage. Preview, No. 138, p. 1-128,
Percival, P.J., 2014. Index of airborne geophysical surveys (Fourteenth Edition).The radiometric, or gamma-ray spectrometric method, measures the natural variations in the gamma-rays detected near the Earth's surface as the result of the natural radioactive decay of potassium (K), uranium (U) and thorium (Th). The data collected are processed via standard methods to ensure the response recorded is that due only to the rocks in the ground. The results produce datasets that can be interpreted to reveal the geological structure of the sub-surface. The processed data is checked for quality by GA geophysicists to ensure that the final data released by GA are fit-for-purpose.<br/> This Macquarie Harbour and Southwest Tasmania, TAS, 1985 (P629), radiometric line data, AWAGS levelled were acquired in 1985 by the TAS Government, and consisted of 4833 line-kilometres of data at 500m line spacing and 188m terrain clearance. To constrain long wavelengths in the data, an independent data set, the Australia-wide Airborne Geophysical Survey (AWAGS) airborne magnetic data, was used to control the base levels of the survey data. This survey data is essentially levelled to AWAGS
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