916 research outputs found
Dynamix on the Frame VM: Declarative dynamic semantics on a VM using scopes as frames
Over the years virtual machines (VMs) have been created to abstract over computer hardware. This simplified code generation and allowed for easy portability between hardware platforms. These VMs are however highly tailored to a particular runtime model. This improves the execution speed, but places restrictions on the types of languages that the VM supports. In this thesis the Frame VM was developed as a VM that supports many different types of languages in a principled way. Achieving this is done by basing the VM on language independent models of memory and control flow. Usage of the scopes-as-frames paradigm and control frames resulted in an instruction set that is relatively small at its core, but does allow for the construction of complex control flow. As an effect, many different programming languages can be compiled to the Frame VM. In addition to this VM, a Domain Specific Language (DSL) for executable semantics of programming languages was created. This language, Dynamix, allows for a modular approach to writing the semantics of a language. Additionally, Dynamix provides a meta-compiler that uses these semantics of a language to compile programs to the Frame VM. To validate the Frame VM, direct compilers for Rust and Prolog have been created in a student project and compilers for Scheme and Tiger were created using Dynamix. Using these semantics of Scheme and Tiger, it was possible to execute programs containing usage of call/cc and a suite of Tiger benchmark programs. Furthermore, the control flow of Tiger was extended with exceptions and generator functions. This extension did not require any changes to the existing semantics, showing the modularity of control achieved when using Dynamix and the Frame VM.Computer Scienc
MIME Configurations for Using VM on Emacs
P(論文)Emacsは単なる文書編集アプリケーションではなく、様々な機能をマクロとして附加することができる。本稿では、このEmacsでメールを読み書きするための追加マクロとしてVMを取り上げる。VMでは電子メール本文におけるMIME対応はなされているが、ヘッダにおけるMIME対応はなされていない。本稿では、VMからSEMIを利用し、電子メールヘッダに日本語を利用するためのMIME設定について述べる。当初の目的であるEmacsとVMによる電子メールヘッダにおける日本語のMIME処理は実現できた。ただし、Emacsの版によってはうまく実現できないという情報もある。汎用的な方法を確立するためには、更なる調査が必要である。Emacs is an application software that can be used not only for editing plain texts but also for many other purposes by adding facilities as macros. In this study, VM was used as auxiliary macro for reading and writing e-mails by Emacs. VM has MIME reading and writing ability in the body part of e-mail messages but not in the header part. In this paper, MIME configurations for using SEMI from VM for processingJapanese characters in e-mail headers are described. The goal of this study, i.e., reading and writing MIME messages in header parts, was achieved. However, the author has information that the method described in this paper does not work well with one version of Emacs (Emacs 22). Establishment of a general method is a subject of future work.departmental bulletin pape
Flow compensation in a MEMS dual-thermal conductivity detector for hydrogen sensing in natural gas
Conventional thermal conductivity detectors (TCDs) demonstrate a flow dependence. The approach presented here to reduce the flow dependence is based on the on-line flow compensation using two thin-film sensors on membranes in parallel on the same chip that are differentially operated. These are laterally identically, but with a different depth of the detection chamber, resulting in different quasi-static sensitivities to the thermal conductivity of the sample gas. The effects of conduction and convection in the structure have been studied using COMSOL Multiphysics. First prototypes have been fabricated and are presently tested.Accepted Author ManuscriptElectronic Instrumentatio
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Clinical trial of CPT-11 and VM-26/VP-16 for patients with recurrent malignant brain tumors
CPT-11 is a potent inhibitor of topoisomerase I and has shown antitumor activity in brain xenografts and in clinical trials in recurrent/progressive malignant glioma. VM-26 and VP-16 are topoisomerase II inhibitors and have also shown activity in phase II trials. We performed a phase II trial of intravenous CPT-11 (125 mg/m2) followed 24 h later by VM-26 (125 mg/m2). VP-16 (125 mg/m2) was later substituted for VM-26 due to drug shortage. For patients on anticonvulsants, the starting dose for all drugs was 150 mg/m2. Drugs were given weekly for 3 weeks followed by 1-week rest. Twenty-five patients were entered into the study. Three patients (12%) had improvement in CAT/MRI brain scans (95% confidence interval 3-31%). Fatigue and myelosuppression, mainly leukopenia, were the main toxicities. This combination of the topoisomerase I inhibitor CPT-11 followed by the topoisomerase II inhibitor, VM-26 or VP-16, has shown modest antitumor activity comparable to that reported for each drug singly. Myelosuppression is the main toxicity when topoisomerase I and II inhibitors are combined together
Who creates the narrative? The case of RE/F/r:ACE, a participatory media artwork in city space
This paper discusses the roles of artist, author, participant and spectator within the context of participatory media art events, with reference to RE/F/r.ACE, a participatory video project developed by Andy Best-Dunkley, Merja Puustinen and Victor Khachtchanski. RE/F/r.ACE enables participants to easily contribute their own images as raw material to the ongoing flow of visual and audio narrative projected into the public city environment. Situating the project within an art historical context, the paper discusses the social and political coding of the architectonic urban environment, and the rules and norms relating to, and controlling, our everyday use of public space. When the notion of free “open to all” public space is under threat from ongoing commercialisation and gentrification of urban centres worldwide, RE/F/r.ACE is an example of one attempt to draw attention to this transformation in a creative, positive, and artistic manner.Peer reviewe
Multisize Electrode Field-of-View: Validation by High Resolution Gadolinium-Enhanced Cardiac Magnetic Resonance
Background: Voltage mapping to detect ventricular scar is important for guiding catheter ablation, but the field-of-view of unipolar, bipolar, conventional, and microelectrodes as it relates to the extent of viable myocardium (VM) is not well defined. Objectives: The purpose of this study was to evaluate electroanatomic voltage-mapping (EAVM) with different-size electrodes for identifying VM, validated against high-resolution ex-vivo cardiac magnetic resonance (HR-LGE-CMR). Methods: A total of 9 swine with early-reperfusion myocardial infarction were mapped with the QDOT microcatheter. HR-LGE-CMR (0.3-mm slices) were merged with EAVM. At each EAVM point, the underlying VM in multisize transmural cylinders and spheres was quantified from ex vivo CMR and related to unipolar and bipolar voltages recorded from conventional and microelectrodes. Results: In each swine, 220 mapping points (Q1, Q3: 216, 260 mapping points) were collected. Infarcts were heterogeneous and nontransmural. Unipolar and bipolar voltage increased with VM volumes from >175 mm3 up to >525 mm3 (equivalent to a 5-mm radius cylinder with height >6.69 mm). VM volumes in subendocardial cylinders with 1- or 3-mm depth correlated poorly with all voltages. Unipolar voltages recorded with conventional and microelectrodes were similar (difference 0.17 ± 2.66 mV) and correlated best to VM within a sphere of radius 10 and 8 mm, respectively. Distance-weighting did not improve the correlation. Conclusions: Voltage increases with transmural volume of VM but correlates poorly with small amounts of VM, which limits EAVM in defining heterogeneous scar. Microelectrodes cannot distinguish thin from thick areas of subendocardial VM. The field-of-view for unipolar recordings for microelectrodes and conventional electrodes appears to be 8 to 10 mm, respectively, and unexpectedly similar.ImPhys/Tao grou
Evaluation of SLA-based decision strategies for VM scheduling in cloud data centers
Copyright © 2016 held by owner/author(s). Service level agreements (SLAs) gain more and more importance in the area of cloud computing. An SLA is a contract between a customer and a cloud service provider (CSP) in which the CSP guarantees functional and non-functional quality of service parameters for cloud services. Since CSPs have to pay for the hardware used as well as penalties for violating SLAs, they are eager to fulfill these agreements while at the same time optimizing the utilization of their resources. In this paper we examine SLA-aware VM scheduling strategies for cloud data centers. The service level objectives considered are resource usage and availability. The sample resources are CPU and RAM. They can be overprovisioned by the CSPs which is the main leverage to increase their revenue. The availability of a VM is affected by migrating it within and between data centers. To get realistic results, we simulate the effect of the strategies using the FederatedCloudSim framework and real-world workload traces of business-critical VMs. Our evaluation shows that there are considerable differences between the scheduling strategies in terms of SLA violations and the number of migrations. From all strategies considered, the combination of the Minimization of Migrations strategy for VM selection and the Worst Fit strategy for host selection achieves the best results
Evaluation of SLA-based decision strategies for VM scheduling in cloud data centers
Copyright © 2016 held by owner/author(s). Service level agreements (SLAs) gain more and more importance in the area of cloud computing. An SLA is a contract between a customer and a cloud service provider (CSP) in which the CSP guarantees functional and non-functional quality of service parameters for cloud services. Since CSPs have to pay for the hardware used as well as penalties for violating SLAs, they are eager to fulfill these agreements while at the same time optimizing the utilization of their resources. In this paper we examine SLA-aware VM scheduling strategies for cloud data centers. The service level objectives considered are resource usage and availability. The sample resources are CPU and RAM. They can be overprovisioned by the CSPs which is the main leverage to increase their revenue. The availability of a VM is affected by migrating it within and between data centers. To get realistic results, we simulate the effect of the strategies using the FederatedCloudSim framework and real-world workload traces of business-critical VMs. Our evaluation shows that there are considerable differences between the scheduling strategies in terms of SLA violations and the number of migrations. From all strategies considered, the combination of the Minimization of Migrations strategy for VM selection and the Worst Fit strategy for host selection achieves the best results
Simple drag prediction strategies for an Autonomous Underwater Vehicle’s hull shape
The range of an AUV is dictated by its finite energy source and minimising the energy consumption is required to maximise its endurance. One option to extend the endurance is by obtaining the optimum hydrodynamic hull shape with balancing the trade-off between computational cost and fluid dynamic fidelity. An AUV hull form has been optimised to obtain low resistance hull. Hydrodynamic optimisation of hull form has been carried out by employing five parametric geometry models with a streamlined constraint. Three Genetic Algorithm optimisation procedures are applied by three simple drag predictions which are based on the potential flow method. The results highlight the effectiveness of considering the proposed hull shape optimisation procedure for the early stage of AUV hull desig
Surrogate models to unlock the optimal design of stiffened panels accounting for ultimate strength reduction due to welding residual stress
In this paper, for the first time, a three-step approach for the optimal design of stiffened panels accounting for the ultimate limit state due to welding residual stress is developed. First, authors rely on state-of-the-art analytical approaches coupled with recently data-driven nonlinear finite element methods surrogates characterized by functional which are computationally expensive to build but computationally inexpensive to use. Then, surrogates are used within a design optimization loop to find new optimal designs since nonlinear finite element methods are too computationally demanding for this purpose. Finally, the new designs are reassessed with the original nonlinear finite element methods to verify that substituting them with their surrogates in the optimization loop actually leads to better designs. Results obtained optimizing a series of parameters of a commonly used stiffened panel geometry under different scenarios will support the authors’ novel approach
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