643 research outputs found
Data from: Metabolomics - Emory Cardiovascular Biobank
No full textUntargeted high-resolution plasma metabolomic profiling among patients with coronary artery disease. Patients recruited from the Emory Cardiovascular Biobank into independent discovery and validation cohorts.This DATSETNAMEreadme.txt file was generated on 2020-08-20 by ANURAG MEHTA and CHANG LIU
GENERAL INFORMATION
1. Title of Dataset: Emory Cardiovascular Biobank Metabolomics
2. Author Information
A. Principal Investigator Contact Information
Name: Arshed A. Quyyumi, MD
Institution: Emory University School of Medicine
Address: 1462 Clifton Road NE, Suite 507, Atlanta, Georgia 30329
Email: [email protected]
B. Associate or Co-investigator Contact Information
Name: Anurag Mehta, MD
Institution: Emory University School of Medicine
Address: 1462 Clifton Road NE, Suite 513, Atlanta, Georgia 30329
Email: [email protected]
C. Alternate Contact Information
Name: Chang Liu
Institution: Emory University School of Medicine
Address: 1462 Clifton Road NE, Atlanta, Georgia 30329
Email: [email protected]
3. Date of data collection: 2004 to 2016
4. Information about funding sources that supported the collection of the data: National Heart, Lung, and Blood Institute grant 1P20HL113451
SHARING/ACCESS INFORMATION
1. Links to publications that cite or use the data: https://doi.org/10.1371/journal.pone.0237579
2. Links to other publicly accessible locations of the data: https://doi.org/10.5061/dryad.866t1g1mt
3. Links/relationships to ancillary data sets: none
4. Was data derived from another source? no
5. Recommended citation for this dataset: Mehta A, Liu C, Quyyumi AA. Emory Cardiovascular Biobank Metabolomics. 2020
DATA & FILE OVERVIEW
1. File List: Analysis_data_first_cohort.csv; Analysis_data_second_cohort.csv
2. Relationship between files: data of two separate cohorts
3. Additional related data collected that was not included in the current data package: none
4. Are there multiple versions of the dataset? no
METHODOLOGICAL INFORMATION: please see description in materials and methods section of the manuscript
DATA-SPECIFIC INFORMATION FOR: Analysis_data_first_cohort.csv
1. Number of variables: 6796
2. Number of cases/rows: 454
3. Variable List:
GENEID: subject IDs
timetodeath3yr: time to death event or censoring at three years
death3yr: death event at three years
age: age in years
male: male gender, 1=male, 0=female
BlackRace: black race, 1=black, 0=non-black
batch: batch of metabolomics profiling
Strokehx: history of stroke, 1=yes, 0=no
CABGhx: prior CABG, 1=yes, 0=no
PVDhx: peripheral artery disease, 1=yes, 0=no
eGFR_max120_lt60: estimated glomerular filtration rate less than 60 ml/min/1.73m2, 1=yes, 0=no
curr_smoking: current smoking, 1=yes, 0=no
HFhx: heart failure history, 1=yes, 0=no
HTN: hypertension, 1=yes, 0=no
DM: diabetes, 1=yes, 0=no
mzXX_tXX: intensities of metabolic features
4. Missing data codes: NA
DATA-SPECIFIC INFORMATION FOR: Analysis_data_second_cohort.csv
1. Number of variables: 8729
2. Number of cases/rows: 322
3. Variable List:
GENEID: subject IDs
timetodeath3yr: time to death event or censoring at three years
death3yr: death event at three years, 1=yes, 0=no
age: age in years
male: male gender, 1=male, 0=female
BlackRace: black race, 1=black, 0=non-black
batch: batch of metabolomics profiling
Strokehx: history of stroke, 1=yes, 0=no
CABGhx: prior CABG, 1=yes, 0=no
PVDhx: peripheral artery disease, 1=yes, 0=no
eGFR_max120_lt60: estimated glomerular filtration rate less than 60 ml/min/1.73m2, 1=yes, 0=no
curr_smoking: current smoking, 1=yes, 0=no
HFhx: heart failure history, 1=yes, 0=no
HTN: hypertension, 1=yes, 0=no
DM: diabetes, 1=yes, 0=no
mzXX_tXX: intensities of metabolic features
4. Missing data codes: NA
Funding provided by: National Heart, Lung, and Blood InstituteCrossref Funder Registry ID: http://dx.doi.org/10.13039/100000050Award Number: 1P20HL113451Funding provided by: American Heart AssociationCrossref Funder Registry ID: http://dx.doi.org/10.13039/100000968Award Number: 19POST34400057Dataset collected as part of Emory Cardiovascular Biobank - a prospective regsitry of patients with coronary artery diseas
Aestheticizing a Political Debate: Can the Creek Confederacy Be Sung Back Together?
No full textSpeaking at Emory University on April 13, 2007, Dr. Womack explores the complex historical relationship between African Americans and the Creek Confederacy through a close reading of two short stories by Creek author Alexander Posey: "Uncle Dick and Uncle Will" (1894) and "Uncle Dick's Sow" (1900)
Unbalanced Bargaining: Trump Entertainment Resorts Unite Here Local 54 and Expired Collective Bargaining Agreements Under § 1113
No full textThe author explores Trump Entertainment Resorts Unite Here Local 54, in which the Third Circuit considered, as an issue of first impression, whether a chapter 11 debtor-employer is able to reject the continuing terms and conditions of an expired collective bargaining agreement with its unionized employees under 11 U.S.C. § 1113. After analyzing this decision, the author argues that expired collective bargaining agreements are not subject to rejection or modification through § 1113. The author concludes by providing recommendations for judges, debtor-employers, and unions that attempt to balance the conflicting policy concerns surround bankruptcy and collective bargaining agreements
A Fly in the Ointment: PROMESA\u27s Drafting Error in Section 314(b)(7)
No full textWhen Congress amended the Bankruptcy Code in 1984, Congress precluded Puerto Rico from seeking bankruptcy relief under chapter 9. The author explores the history of this exclusion, the case Puerto Rico v. Franklin California Tax-Free Trust, and § 314(b)(7) of the Puerto Rico Oversight Management and Economic Stability Act. The author then concludes that § 314(b)(7) should be removed to resolve the dysfunction it creates
Third-Party Relief for Municipal Debtors: \u27Necessity\u27 in the Chapter 9 Context
No full textBankruptcy courts have often used \u27third-party releases\u27 in the chapter 11 context to release certain non-debtors from liabilities. As chapter 9 municipal bankruptcies have become more numerous, debtors have sought third-party relief there as well. The author categorizes these chapter 9 cases into two categories. The first involves cases where the State provides funds to the reorganization effort in exchange for some creditors giving up claims against the State. The second consists of cases where a city attempts to relieve its police officers of liability for civil rights violations by including injunctions against the civil rights plaintiffs in the city\u27s plan of reorganization. The author argues that the second category of cases have ignored fundamental limitations on third-party relief and allow debtors to exploit a test that was not intended for chapter 9 bankruptcy. This leads the author to propose replacing the \u27necessity\u27 standard with one suited for municipal bankruptcies
It\u27s Not You, It\u27s Us: Assessing the Contribution of Trademark Goodwill to Properly Balance the Results of Trademark License Rejection
No full textIn 1988, Congress amended § 365 of the Bankruptcy Code to allow intellectual property licenses to retain usage rights following the rejection of an executory contract. Unfortunately, this amendment did not include trademarks in its definition of intellectual property. The author thoroughly examines the circuit split, comparing and contrasting the dueling circuit court decisions over whether trademark licenses should receive the same protections as other intellectual property. In analyzing this circuit split, the author centrally focuses on Mission Product Holdings, Inc. v. Tempnology, LLC, a case out of the First Circuit Court of Appeals. The author concludes by proposing a three-factor test to aid courts in arriving at the most equitable result for not only the debtor\u27s estate, but also society writ-large
Protecting Free Speech in Social Media: A Pathway to Self-Determination in International Law
No full textWith the growth of Internet and social media usage, state regulatory action to surveil and censor citizens is running rampant. As the principle of self-determination stands, minority populations are typically bearing the brunt of these attacks, receiving little protection under domestic and international law. Self-determination within international law must be restructured into a definitive pathway that includes protecting the freedom of speech to encourage discourse and tolerance between the State and its minority populations. This article proposes a solution that could fill the gap in international law formed by insufficient domestic rule in States that neglect to protect these populations in the age of the Internet.
By incorporating the freedom of speech into the principle of self-determination, States would be encouraged to think before detrimentally enabling censorship as the primary means to protect territorial integrity and State security. History reflects that by restricting the speech and identity of individuals, conflict becomes inevitable. This is vividly illustrated by the centuries-long cultural crusade in Catalonia by the Spanish government. It has been proven repeatedly that people will not sit by quietly while their cultural, political, or social structure is erased. To prevent future conflict, people must know that they have a voice that will be heard. Social media accomplished this.
This publication is a shortened form of the original article which contains a second case study on the Hong Kong independence movement. The full version is available on request to the author
Government Recovery of Medicare Overpayments and the Automatic Stay
No full textDespite the importance of the automatic stay, in healthcare bankruptcies it is not always applied consistently, especially when the government is the creditor. Government agencies decide whether they will require the bankrupt healthcare provider to repay any Medicare overpayments previously paid. As such, government agencies may jump other creditors based on the equitable doctrine of recoupment. Recoupment is a doctrine recognized by bankruptcy courts allowing for creditors to offset their debts against payments. This is similar to setoff, an action that is not permitted under the Code. The author argues that government agencies should not be allowed to continue recoupment actions against healthcare entities that will jeopardize their reorganization processes. The author suggests that courts can fix this issue by narrowly applying the doctrine of recoupment and reducing the circumstances in which government agencies can collect from bankrupt healthcare entities without seeking relief from the automatic stay
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