10 research outputs found
The LED spectral power distribution modelled by different functions - how spectral matching quality affected computed LED color parameters
No full textSelecting Energy-Efficient LED Retrofits with Optimal Color Qualities for New and Refurbished Buildings
No full textThis study carried out a literature search and selection in accordance with the PRISMA 2020 protocol to conduct a complete review of the literature describing the electrical, photometrical, and colorimetric parameters of LEDs. Based on it, a significant research gap was found in the field of LED-based lighting retrofits. We prove that there is a lack of publications indicating the relationship between the energy consumption of LED retrofits and user preferences concerning the quality of lighting. This article presents an effective new method for selecting LEDs to retrofit typical 3000, 4000, and 6500 K fluorescent lighting installations in buildings. It is shown that when selecting an LED replacement for a fluorescent source, consideration of the classically used parameters in the field of lighting technology to describe the quality of white light, specifically correlated color temperature and the color rendering index, is insufficient. We demonstrate that energy efficiency and the color preference criteria for retrofitted LEDs must be considered and balanced with the potential impact on circadian rhythms as assessed by the melanopic daylight efficacy ratio. This research proves that LED replacements with the best color preference properties (P1 class in the CPC classification of ANSI/IES TM30-20 method) correspond to the least energy-efficient light sources
The Influence of Spectral Measurements Uncertainty of Fluorescent Lamps on Calculated Value of Their Relative Melanopic Weighted Irradiance and Colour Quality Parameters
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Inside Back Cover: TNU-9 Zeolite: Aluminum Distribution and Extra-Framework Sites of Divalent Cations (Chem. Eur. J. 37/2017)
No full textThe effect of chronic alcohol intoxication and smoking on the activity of oral peroxidase The effect of chronic alcohol intoxication and smoking on the activity of oral peroxidase
No full textPeroxidase is the most important antioxidant enzyme in saliva. Through peroxidation of thiocyanate in<br />the presence of H2O2, peroxidase catalyses the formation of bacteriocidic compounds such as hypothiocyanate.<br />The purpose of this study was to evaluate the effect of chronic alcohol intoxication and smoking on the activity<br />of oral peroxidase (OPO). A total of 37 volunteers participated in the study. This cohort consisted of 17 male<br />alcohol-dependent smoking patients after chronic alcohol intoxication (AS group, alcohol + smoking) (mean<br />age: 42 years; range: 26–55) (100–700 g/day of alcohol; 10–20 cigarettes/day) and 20 control male social drinkers<br />(CNS group, control non-smokers) with no history of alcohol abuse or smoking (mean age: 42 years; range:<br />30–53). Salivary peroxidase activity was measured by the colorimetric method. The differences between groups<br />were evaluated using the Mann–Whitney U test. There was significantly higher activity of OPO (p = 0.00001)<br />and significantly lower salivary flow (SF) (p = 0.007) in alcohol-dependent smokers after chronic alcohol intoxication<br />compared to the control group. OPO activity significantly correlated with the number of days of alcohol<br />intoxication, but not with smoking. Gingival index (GI) was significantly higher in smoking alcohol-dependent<br />persons than in the control group, and correlated with OPO activity. The sensitivity of the OPO test was 70% in<br />smoking alcoholics, while specificity was 95%. The increased activity of OPO suggests chronic oxidative stress is<br />more likely due to ethanol action than to smoking. Smoking alcohol-dependent persons have a worse periodontal<br />status than controls. OPO activity as a marker of chronic alcohol abuse may help in the diagnosis of alcoholism.Peroxidase is the most important antioxidant enzyme in saliva. Through peroxidation of thiocyanate in<br />the presence of H2O2, peroxidase catalyses the formation of bacteriocidic compounds such as hypothiocyanate.<br />The purpose of this study was to evaluate the effect of chronic alcohol intoxication and smoking on the activity<br />of oral peroxidase (OPO). A total of 37 volunteers participated in the study. This cohort consisted of 17 male<br />alcohol-dependent smoking patients after chronic alcohol intoxication (AS group, alcohol + smoking) (mean<br />age: 42 years; range: 26–55) (100–700 g/day of alcohol; 10–20 cigarettes/day) and 20 control male social drinkers<br />(CNS group, control non-smokers) with no history of alcohol abuse or smoking (mean age: 42 years; range:<br />30–53). Salivary peroxidase activity was measured by the colorimetric method. The differences between groups<br />were evaluated using the Mann–Whitney U test. There was significantly higher activity of OPO (p = 0.00001)<br />and significantly lower salivary flow (SF) (p = 0.007) in alcohol-dependent smokers after chronic alcohol intoxication<br />compared to the control group. OPO activity significantly correlated with the number of days of alcohol<br />intoxication, but not with smoking. Gingival index (GI) was significantly higher in smoking alcohol-dependent<br />persons than in the control group, and correlated with OPO activity. The sensitivity of the OPO test was 70% in<br />smoking alcoholics, while specificity was 95%. The increased activity of OPO suggests chronic oxidative stress is<br />more likely due to ethanol action than to smoking. Smoking alcohol-dependent persons have a worse periodontal<br />status than controls. OPO activity as a marker of chronic alcohol abuse may help in the diagnosis of alcoholism
Osteoconductivity and Osteoinductivity of Puros® DBM Putty
No full textBone graft substitutes have been developed due to the limited supply and morbidity associated with using autogenous graft material. Allogeneic demineralized bone matrix (DBM) has been used extensively as a clinical graft material because of its inherent osteoinductive and osteoconductive properties. Differential enhancement of these properties may optimize the performance of these products for various orthopedic and craniofacial applications. Commercially available bone paste products consist of formulations that combine DBM with a carrier to facilitate handling and containment. In the present study, we present results of a comprehensive in vitro and in vivo characterization of a 100% human DBM putty product, Puros DBM Putty. Results indicate the DBM particles are completely dispersed in the putty. Data are presented showing the porosity of and cell attachment to Puros DBM Putty, thereby demonstrating the osteoconductive properties of this DBM. Puros DBM Putty was also shown to be osteoinductive in the rat ectopic pouch model. We demonstrate here for the first time that Puros DBM Putty maintains its activity to markedly stimulate or induce bone formation over the entire period of its shelf life. Taken together, these data demonstrate that the 100% human allograft derived Puros DBM Putty could be an effective bone graft substitute.</jats:p
Severe Breakthrough COVID-19 Cases during Six Months of Delta Variant (B.1.617.2) Domination in Poland
No full textThe emergence of a highly transmissible and a more pathogenic B.1.617.2 (delta) variant of SARS-CoV-2 has brought concern over COVID-19 vaccine efficacy and the increased risk of severe breakthrough infections. The objective of this study was to assess the frequency and the clinical characteristics of severe breakthrough COVID-19 cases recorded in 10 Polish healthcare units between 1 June and 31 December 2021, a period during which a rapid surge in the share of B.1.617.2 infections was seen, while a significant number of populations were already fully vaccinated. Overall, 723 individuals who completed the initial vaccination regime (fully vaccinated group) and an additional 18 who received a booster dose were identified—together, they represented 20.8% of all the COVID-19 patients hospitalized during the same period in the same healthcare institutions (0.5% in the case of a group that received a booster dose). Although laboratory and clinical parameters did not differ between both groups, patients who received a booster tended to have lower CRP, IL-6, PCT, and d-dimer levels and they required oxygen therapy less frequently. The most common early COVID-19 symptoms in the studied group were fatigue, cough, fever (>38 °C), and dyspnea. Individuals with no detectable anti-spike IgG antibodies constituted 13%; the odds of being a humoral non-responder to the vaccine were increased in patients aged >70 years. Fully vaccinated patients hospitalized after more than 180 days from the last vaccine dose were significantly older and they were predominantly represented by individuals over 70 years and with comorbidities, particularly cardiovascular disease. Contrary to mRNA vaccines, most patients vaccinated with adenoviral vector vaccines were infected within six months. A total of 102 fatal cases (14% of all deaths among vaccinated individuals; 0.7% in the case of a group that received a booster dose) were recorded, representing 17.6% of all the COVID-19 fatalities recorded in June–December 2021 in the considered healthcare units. The odds of death were significantly increased in men, individuals aged >70 years, patients with comorbidities, and those identified as humoral non-responders to vaccination; in fully vaccinated patients the odds were also increased when the second vaccine dose was given >180 days before the first COVID-19 symptoms. The mortality rate in immunocompromised subjects was 19%. The results indicate that compared to vaccinated individuals, severe COVID-19 and deaths in the unvaccinated group were significantly more prevalent during the B.1.617.2-dominated wave in Poland; and, it highlight the protective role of a booster dose, particularly for more vulnerable individuals
