2,225 research outputs found

    A 5-year-old case of choroidal neovascularization in enhanced s-cone syndrome treated with ranibizumab

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    Introduction: We describe the youngest case of enhanced S-cone syndrome (ESCS) associated with choroidal neovascularization (CNV) successfully treated with intravitreal ranibizumab injections. Case Report: A 5-year-old boy presented with round-shaped fibrotic subretinal lesions in both eyes with surrounding subretinal fluid and progressive visual deterioration in the right eye. Fine foci of increased autofluorescence were observed along the arcades in both eyes. Fluorescein angiography revealed the presence of CNV in his right eye, and treatment with ranibizumab was initiated, with significant improvement in vision. Subsequent electroretinogram examination and genetic studies of the patient and his two younger siblings confirmed the diagnosis of ESCS. Conclusion: CNV has been reported to occur in different inherited retinal degenerations, including ESCS. Our experience confirms that treatment with ranibizumab in patients with CNV-complicated ESCS can be potentially vision-saving

    "The love that made hell, paradise." Ouida re-writing the Paolo and Francesca theme in Held in Bondage

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    The bestselling Victorian author Ouida reveals in her novels, and, in particular, Held in Bondage, an extraordinary knowledge od Dante, by using characters and themes from the Commedia. The Paolo and Francesca theme actually constitutes part of the plot of the novel and is to be found in many of her other works, short stories and non-fiction writing

    HERStory Makers 2023: Francesca Fotheringham

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    Francesca Fotheringham is a postdoctoral research associate at the University of Edinburgh studying educational psychology with a focus on neurodiversity. She took part in HERStory Makers 2023.What is HERStory Makers?HERStory Makers is a social media competition for female-identifying early career researchers to share their research, their career journeys, and to inspire the next generation. Winners are selected by public vote. HERStory Makers is also part of EXPLORATHON, Scotland's contribution to European Researchers' Night.In 2022-23, EXPLORATHON Francescasupported by the Engineering & Physical Sciences Research Council [grant number EP/X020762/1].Author contributions to contentFrancesca conceived, planned, and recorded the video content. Kirsty Ross edited the video content to insert HERStory Maker credits, added subtitles, and reduce video length to below Twitter/X limit of 2 mins and 20 secs.</p

    Medicina illuminata. La Biblioteca Lancisiana di Roma

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    L'articolo presenta i codici miniati della Biblioteca Lancisiana di Roma. La prima parte, del coautore, è dedicata alla Biblioteca. La seconda parte, di F. Manzari, tratta dei manoscritti miniati, costituiti da due codici con le opere di Avicenna e dal Liber fraternitatis della Confraternita dell'Ospedale di Santo Spirito in Sassia a Roma.The article introduces the illuminated manuscripts of the Biblioteca Lancisiana in Rome. The first part of the article, by the co-author, is dedicated to the Library. The second part, by Francesca Manzari, illustrates the manuscipts; these are two manuscripts with the works of Avicenna and the Liber fraternitatis of the Confraternity of the Hospital of Santo Spirito in Sassia in Rome

    Multi-Channel Spectral Analysis of Non-Synchronous Vibrations of Bladed Disks Measured by Blade Tip Timing

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    The paper proposes a method for the processing of BTT data deriving from non-synchronous vibrations measured at constant rotor speed by a set of non-uniformly distributed sensors. The sampled data are interpreted as members of a vector space whose characteristics are determined by the signal itself and by sampling pattern. If the signal contains a single harmonic component, its frequency can be estimated through a method that has been named harmonic matching. On the contrary, when more than one harmonic component is present, due to a multi-modal response, a component separation processing is necessary. To this purpose, it is proposed a technique based on the Independent Component Analysis (ICA). This approach is limited to constant speed regime, but has the benefit of using statistical estimators that enable a strong resistance to noise. The method is illustrated using academic examples and is employed to study a flutter-like non-synchronous vibration of a bladed disk

    sj-docx-1-tau-10.1177_17562872241229260 – Supplemental material for The impact of prognostic group classification on prostate cancer progression in intermediate-risk patients according to the European Association of Urology system: results in 479 patients treated with robot-assisted radical prostatectomy at a single tertiary referral center

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    Supplemental material, sj-docx-1-tau-10.1177_17562872241229260 for The impact of prognostic group classification on prostate cancer progression in intermediate-risk patients according to the European Association of Urology system: results in 479 patients treated with robot-assisted radical prostatectomy at a single tertiary referral center by Antonio Benito Porcaro, Alberto Bianchi, Andrea Panunzio, Sebastian Gallina, Alessandro Tafuri, Emanuele Serafin, Rossella Orlando, Giovanni Mazzucato, Stefano Vidiri, Damiano D’Aietti, Francesca Montanaro, Giulia Marafioti Patuzzo, Francesco Artoni, Alberto Baielli, Francesco Ditonno, Riccardo Rizzetto, Alessandro Veccia, Alessandra Gozzo, Vincenzo De Marco, Matteo Brunelli, Maria Angela Cerruto and Alessandro Antonelli in Therapeutic Advances in Urology</p

    A DH-Leavened Musicological Toolbox

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    Graduate-level training in music research methodologies tends to ignore digital humanities work and overlook the use of digital tools created in support of new forms of reading. Training instead focuses on source material in the student’s area of interest. This material includes secondary and primary (archival) resources, as well as information resources, such as: monuments of music and critical editions; indexes; bibliographies and thematic catalogs; dictionaries and encyclopedias; digital libraries of scores or editions; and databases of period-specific newspapers or journals. Graduate students taking research methods courses already have a toolbox built from their experiences as musicians and students of music, including the ability to read and interpret music notation, to understand theoretical and analytical concepts in music, as well as a command of music history, including the canon of musical works. Digital humanities has become a major area of academic endeavor at the “interface of technological development, epistemological change and methodological concerns." An important characteristic of digital humanities research has been its interdisciplinarity. We argue that graduate training in musicology needs to include coverage of methodologies applied by digital humanists in support of new forms of reading, not only to broaden the canon of research topics in musicology, but also to build common ground with researchers of other disciplines. We propose that librarians are well positioned to provide this expertise and training

    A Twitter Case Study for Assessing Digital Sound

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    Academic and cultural heritage institutions around the world have made measurable strides in the development of digital sound archives oriented towards research and access, but their impact on scholarship and society has been little studied. Traditionally, impact has been measured by citations; yet these are problematic metrics for non-traditional outputs like sound recordings. Social media data provide a promising avenue of investigation for measuring scholarly as well as societal impact. Twitter in particular has been shown to provide a high number of references for cultural and research outputs in all disciplines. This study analyzes Twitter references pertaining to the collections of five digital sound archives: British Library Sounds, Europeana Sounds, the Internet Archive Audio Archive, PennSound and UbuWeb. Using text analysis methods to identify high frequency events and trends, and labeling them with a rubric designed for measuring the impact of digital heritage resources, this study provides preliminary insights on user values as they relate to digital sound collections. Despite the limitations of using social media data, the evidence gathered in this case study characterizes aspects of the use of digital sound collections, and may point to future priorities for the digital preservation of sound.Peer reviewe
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