60 research outputs found
Mercados, Fiscalidad y Cuestión Regional en la obra de Chiaramonte
No full textThis article is a reviewed version of a paper presented by the author at the conference “Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones”, based on the work of Jose Carlos Chiaramonte on markets, taxation and region.El presente artículo es una versión revisada de la ponencia presentada por Roberto Schmit en las Jornadas “Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones”, sobre la obra de José Carlos Chiaramonte en torno a mercados, fiscalidad y cuestión regional
Homenaje a José Carlos Chiaramonte. Formas de pensar la historia
No full textThis article is a reviewed version of a paper presented by the author at the conference “Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones”, based on the work of Jose Carlos Chiaramonte on the different ways of thinking about History.El presente artículo es una versión revisada de la ponencia que el autor presentó en las Jornadas “Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones”, sobre la obra de José Carlos Chiaramonte en torno a las formas de pensar la historia.
Mercado, fiscalidad y cuestión regional en la obra de Chiaramonte
Get PDFEl presente artículo es una versión revisada de la ponencia que el autor presentó en las Jornadas "Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones", sobre la obra de José Carlos Chiaramonte en torno a mercados, fiscalidad y cuestión regional.This article is a reviewed version of a paper presented by the author at the conference "Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones", based on the work of Jose Carlos Chiaramonte on markets, taxation and region.Fil: Schmit, Roberto Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto de Historia Argentina y Americana "Dr. Emilio Ravignani". Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Historia Argentina y Americana "Dr. Emilio Ravignani"; Argentin
Estado, nación y federalismos en el siglo XIX. La contribución de José Carlos Chiaramonte
No full textThis article is a reviewed version of a paper presented by the author at the conference “Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones”, based on the work of José Carlos Chiaramonte around Nation, State and Federalism during the 19th Century.El presente artículo es una versión revisada de la ponencia que el autor presentó en las Jornadas “Pensar la historia rioplatense entre el fin del Imperio y la construcción de las naciones”, sobre la obra de José Carlos Chiaramonte en torno a Estado, nación y federalismos en el siglo XIX
Chiaramonte Gulfi an experience of urban morphology
No full textThis paper is aimed to describe a project for the city of Chiaramonte Gulfi elaborated during the International Laboratory of Architecture_LId’A coordinated by Laura Thermes. In one of the laboratories – directed by the author with Federica Visconti and coordinated to those by Carlo Moccia and Marco Mannino – the team worked on the redefinition of the “city walls”. Over the 1970s, it resulted from the construction of a continuous line of buildings in relationship to agricultural divisions and peri-urban plots. The thin strip determined, on one hand, a new “urban artifact” of morphological value – even if of less architectural value – as a kind of city walls of the ancient city, and, on the other, it opposed the typical nebulized growth of the sprawl-city. The project aims to propose a comprehensive reformulation for this wall, working in some of the significant places, highlighting discontinuities, openings the city to the landscape and establishing new relationships between the Comiso’s plain below and the perched character – like in the acropolis – of the medieval centre, re-entering portions of nature still existing in the urban fabric. The project combines two ways of architectural composition, the stereotomic and the tectonic, and develops the theme of the bastion corresponding to a hiatus of the wall, proposing a new condition overlooking towards the landscape of the Comiso plain and, at the same time, representing an element of a distinctive and interconnected system of “places” able to establish long distance relationships and summarize the whole urban morphology and the geography of Chiaramonte
Publication date and author spelling for the hidden angelshark Squatina occulta
Get PDFTwo dates of publication have been associated with the hidden angelshark Squatina occulta. Additionally, the name of the second author of this species has been cited with different spellings in different publications. Both inconsistencies are addressed in this study. It is suggested that the hidden angelshark be consistently cited as Squatina occulta Vooren & da Silva 1991.Fil: Faria, V. V.. Universidade Federal do Ceará. Instituto de Ciências do Mar; BrasilFil: Chiaramonte, Gustavo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; ArgentinaFil: Van Oijen, M. J. P.. Naturalis Biodiversity Center; Países Bajo
An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors
Get PDFBotulinum toxins are neurotoxins produced by Clostridium botulinum. This toxin can be lethal for humans as a cause of botulism; however, in small doses, the same toxin is used to treat different conditions. Even if the therapeutic doses are effective and safe, the adverse reactions could be local and could unmask a subclinical impairment of neuromuscular transmissions. There are not many cases of adverse events in the literature; however, it is possible that sometimes they do not occur as they are transient and, if they do occur, there is no possibility of a cure other than to wait for the pharmacological effect to end. Inhibition of botulinum neurotoxin type A (BoNT/A) effects is a strategy for treating botulism as it can provide an effective post-exposure remedy. In this paper, 13,592,287 compounds were screened through a pharmacophore filter, a 3D-QSAR model, and a virtual screening; then, the compounds with the best affinity were selected. Molecular dynamics simulation studies on the first four compounds predicted to be the most active were conducted to verify that the poses foreseen by the docking were stable. This approach allowed us to identify compounds with a calculated inhibitory activity in the range of 316–500 nM
The ancient Constitution in Río de La Plata during the first half of the 19th century
Get PDFFil: Chiaramonte, José Carlos. Universidad de Buenos Aires. Facultad de Filosofía y Letras; Argentina.Fil: Chiaramonte, José Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Historia Argentina y Americana “Dr. Emilio Ravignani; Argentina.La Conferencia propone un recorrido por las principales tesis de la original obra del autor. Inicia con su tesis principal, la negación de la preexistencia de la nación argentina al proceso de revolución de independencia colonial. Luego propone una segundatesis que cuestiona el uso naturalizado de la idea de federalismo en la historia pos independencia en el Río de La Plata y por último destaca la tesis de la existencia de una “Constitución antes de la Constitución”, o la “Antigua Constitución”: idea que cuestiona los prejuicios históricos respecto a la existencia de una anarquía o anomia en el periodo posindependencia contraponiéndola a la de una época donde un cuerpo de leyes y normas, no siempre escritas, ordenaban la vida de estos pueblos, en la que se destaca la más importante de las normas del derecho natural: el libre consentimiento.The following conference proposes a journey through the main thesis present in the work of the author. It begins with the central thesis, the denial of the Argentine nation preexistence related to the revolution of colonial independence. Later proposes a second thesis that questions the naturalized use of the idea of federalism in the post-independence history in Río de La Plata and finally it highlights the idea of the existence of a “Constitution before the Constitution” or an “Ancient Constitution”: that challenges the historic prejudices over the existences of anarchy or anomy during the post-independence period against the idea of a time when a body of laws and rules, usually unwritten, ordered the life of the people. This emphasizes the most important rule of the natural right: free will
Effects of high-flow nasal therapy on swallowing function: a scoping review
No full textBackground High-flow nasal therapy (HFNT) is widely used in patients with respiratory failure in different clinical settings, but the effect of HFNT on respiratory-swallow coordination is unknown. Understanding this relationship is crucial, considering the necessity for patients to maintain adequate nutrition during daytime HFNT.
Purpose This scoping review aims to synthesise available data on the effects of HFNT flow rates on swallowing function and the possible risk of aspiration during treatment, focusing on knowledge and evidence gaps.
Methods PubMed, Scopus, Web of Science and Google Scholar databases were searched from inception to May 30th, 2023, for studies reporting data on swallowing assessment in healthy adults or patients with acute or chronic respiratory failure receiving HFNT. Data on study design, patients’ characteristics, and quality outcomes were extracted, and risk of bias was assessed.
Results Eight studies were included, four including cohorts of healthy volunteers (n=148) and four including patients with acute or chronic respiratory failure (n=151). Study designs, patient populations, and quality outcome measures were heterogeneous. Two studies indicated improvement, while four articles showed impairment in swallowing function during HFNT; two studies showed that patients’ overall clinical picture and underlying medical conditions influence swallowing-breathing coordination rather than HFNT per se. Risk of bias was judged low for all the included studies.
Conclusion This scoping review found limited and controversial evidence of the impact of HFNT on swallowing function. Remarkably, methods for swallowing function assessment were quite heterogeneous. Additional research is required to test the effect of HFNT on respiratory-swallowing coordination
Rehabilitation approach in robot assisted total knee arthroplasty: an observational study
Get PDFBackground The purpose of this study is to evaluate the impact of total knee arthroplasty (TKA) with the aid of
Navio Robot, comparing it with standard prosthetic surgery on the functional outcomes of patients after an intensive
rehabilitation program.
Method A case–control observational study was conducted on patients undergoing TKA for severe KOA. All patients
underwent the same intensive hospital rehabilitation program of 14 daily sessions lasting 3 h. The following rating
scales were administered: Numeric Rating Scale (NRS), Knee Society Score (KSS) and 12-Item Short Form Survey scale.
Patient assessments were performed 1 week post-surgery (T0), 1 month post-surgery (T2), and 3 months post-surgery
(T3). The primary outcomes were active knee extension and fexion and pain severity. The secondary outcomes were
functional capacity and quality of life.
Results Using repeated measures ANOVA, we observed at T1 a statistically diferent diference for the treatment
group compared to the control group about KSS (p<0.05), pain (p<0.05), and knee fexion (p<0.05). No statisti cally signifcant diference between the two groups was observed for knee extension (p=0.09) and the SF-12 scale
(p=0.52). At T2 instead, we observed a statistically signifcant diference for the treatment group compared to the
control group as regards KSS (p<0.05) and knee fexion (p<0.05), while no statistically signifcant diference was
observed for pain (p=0.83), knee extension (p=0.60), and the SF-12 scale (0.44).
Conclusions Our study has demonstrated that robot-NAVIO assisted knee prosthesis surgery, associated with a spe cifc intensive rehabilitation treatment, in the short and medium term, determines good pain control, better fexion
recovery and a improvement of functional capacit
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