2,113 research outputs found
Access to the urgent resuscitation by non medical hospital attendants
No full textANOTATION Author: Ivana Kantůrková Institution: Institute of social medicine Department of nursing Name of work: ACCEST TO THE URGENT RESUSCITATION BY NON MEDICAL HOSPITAL ATTENDANTS Supervisor: Mgr. Ivana Kupečková, MBA Number of pages: 92 Number of enclosure: 3 Year of defence: 2012 Key words: history of resuscitation, Guidelines 2010, knowledges of non medical hospital attendants The teoretical part of my bachelor's thesis deals about history of resuscitation, about developement of resuscitation procedures to the present, when new rules of resuscitation obtain - Guidelines 2010. The empiry part of my thesis find out the level of knowledges from cardio - pulmonary resuscitation of non medical hospital attendants. Research was performed in three institutions, in Policlinic Moravská Třebová, Social service of the city Moravská Třebová and in Hospital of following care in Moravská Třebová. Research took up in October and November 2011, it was realization by anonymous form of guestionnaire
The Croatian Woman Philosopher Ivana Rossi on the Philosophy of Henry Bergson
No full textIvana Rossi (1892.–1963.) prva je Hrvatica koja je 1916. godine na Zagrebačkom sveučilištu doktorirala filozofiju tezom Osnovne misli filozofije Henri Bergsona. Profesionalno je radila kao gimnazijska profesorica. Objavila je dva rada: članak Nekoliko misli Henri Bergsona o estetici (1929.) i prijevod s engleskoga Peter Pan u perivoju Kensington (1922.). Ovdje donosim gotovo nepoznatu biografiju Ivane Rossi, sažetak njezine disertacije i pregled recepcije Bergsonove filozofije u nas.The Croatian woman philosopher Ivana Rossi (1892–1963) was the first Croatian woman to defend a doctorate in philosophy in 1916 at the Faculty of Philosophy in Zagreb. The topic of her dissertation was „The Basic Thoughts of Henry Bergson’s Philosophy“ (Osnovne misli filozofije Henri Bergsona). This dissertation was written much before Henri Bergson’s death in 1941, while he was professionally still very active. Ivana Rossi’s dissertation is the first serious presentation of Henri Bergson’s philosophical thought among the South Slavs. For hitherto unknown reasons — mostly likely personal — Ivana Rossi did not even attempt to work as a professional philosopher in the Academia. (She spent her entire professional career as a high school teacher in Zagreb, working in three different gymnasia: the “Kraljevska ženska realna gimnazija”, the “Partizanska realna gimnazija”, and the “III. muška realna gimnazija”.) In 1929, she published the article, „Some of Henri Bergson’s Thoughts on Aesthetics“ in the journal Književnik. Her second published work is her translation of James Barrie’s „Peter Pan in Kensington Park“ published in 1922. This book is the first Croatian translation of a book on Peter Pan. In this article, in addition to the hitherto little–known biography of Ivana Rossi and the reception of Bergson’s philosophy in Croatia, the author also presents a summary of her dissertation
The triterpenoid curcumene mediates the relative hydrophilicity of Bacillus subtilis spores
No full text: Spores of Bacillus subtilis are surrounded and protected by the coat and the crust, multi-layered structures mainly made of proteins and polysaccharides. These polysaccharides are covalently linked to some of the coat and crust proteins and influence some spore properties, such as surface adhesion and hydrophilicity. This study reports that a mutant strain lacking the spsA-L operon, encoding 11 enzymes involved in the synthesis of spore surface polysaccharides, produced spores exposing on their surface hydrophobic molecules that were responsible for the drastic reduction of hydrophilicity of the mutant spores. Biochemical and genetic data support the identification of the C35-terpenoid curcumene, a precursor of the spore-associated lipid sporulene, as the highly hydrophobic molecule present on the surface of mutant spores.IMPORTANCEBacterial spores are the most resistant cell forms on Earth. The metabolically quiescent spores withstand conditions that would be lethal for other cells, maintaining the capacity to sense the environment and respond to the presence of favorable conditions by germinating. Such remarkable resistance is also due to the complex layers that surround the spore cytoplasm and protect it against damaging factors. Altogether, the spore surface layers form a complex cell structure composed of proteins, polysaccharides, and, as highlighted by this study, also of lipids. Understanding the complexity of the spore surface and the specific molecules involved in its structure is an essential step for unraveling the mechanisms underlying the spore's resistance to environmental assaults
Western blot analysis of markers of endothelial dysfunction in mice aorta following high-fat diet administration
No full text7 2. ABSTRACT Charles University, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Title of Thesis: Western blot analysis of markers of endothelial dysfunction in mice aorta following high-fat diet administration Supervisor: RNDr. Ivana Němečková, Ph.D. Author: Ivana Střelcová Background: High dietary fat intake is associated with increased risk of developing various metabolic diseases, including increased cardiovascular risk. The aim of this thesis was to investigate whether the administration of the high-fat diet containing 42 % kcal of fat affects expression of selected markers of endothelial dysfunction, the key mechanism in development of cardiovascular complications. Methods: In this thesis were evaluated changes in the expression of endothelial nitric oxide synthase (eNOS), endoglin (ENG), endothelin-1 (ET-1), intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1). An experimental group of male C57BL/6J mice aged 7 months was fed the high-fat diet containing 42% kcal of fat for 12 weeks. The control group was fed a standard laboratory diet. Western blot analysis followed by detection using a chemiluminescent reagent was used to evaluate the observed markers of endothelial dysfunction Results: The results show that there were no..
Western blot analysis of markers of endothelial dysfunction in mice aorta following high-fat diet administration
No full text6 1. ABSTRAKT Univerzita Karlova, Farmaceutická fakulta v Hradci Králové Katedra biologických a lékařských věd Název diplomové práce: Western blot analýza markerů endotelové dysfunkce v myší aortě po podávání vysokotukové diety Vedoucí práce: RNDr. Ivana Němečková, Ph.D. Autor: Ivana Střelcová Cíl práce: Vysoký příjem tuků v potravě bývá spojen se zvýšeným rizikem rozvoje různých metabolických onemocnění včetně zvýšeného kardiovaskulárního rizika. Cílem této diplomové práce bylo zjistit, zda podávání vysokotukové diety s obsahem 42 % kcal tuku má vliv na expresi vybraných markerů endotelové dysfunkce, která představuje klíčový mechanismus v rozvoji kardiovaskulárních komplikací. Metody: V práci byly sledovány změny v expresi endotelové syntázy oxidu dusnatého (eNOS), endoglinu (ENG), endotelinu-1 (ET-1), intercelulární adhezní molekuly 1 (ICAM- 1) a vaskulární adhezní molekuly 1 (VCAM-1). Experimentální skupině myších samců kmene C57BL/6J ve věku 7 měsíců byla po dobu 12 týdnů podávána vysokotuková dieta s obsahem 42 % kcal tuku. Kontrolní skupina byla krmena standardní laboratorní dietou. K hodnocení pozorovaných markerů endotelové dysfunkce byla použita Western blot analýza s následnou detekcí za využití chemiluminiscenčního činidla. Výsledky: Výsledky ukazují, že nedošlo k signifikantním změnám v expresi...7 2. ABSTRACT Charles University, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Title of Thesis: Western blot analysis of markers of endothelial dysfunction in mice aorta following high-fat diet administration Supervisor: RNDr. Ivana Němečková, Ph.D. Author: Ivana Střelcová Background: High dietary fat intake is associated with increased risk of developing various metabolic diseases, including increased cardiovascular risk. The aim of this thesis was to investigate whether the administration of the high-fat diet containing 42 % kcal of fat affects expression of selected markers of endothelial dysfunction, the key mechanism in development of cardiovascular complications. Methods: In this thesis were evaluated changes in the expression of endothelial nitric oxide synthase (eNOS), endoglin (ENG), endothelin-1 (ET-1), intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1). An experimental group of male C57BL/6J mice aged 7 months was fed the high-fat diet containing 42% kcal of fat for 12 weeks. The control group was fed a standard laboratory diet. Western blot analysis followed by detection using a chemiluminescent reagent was used to evaluate the observed markers of endothelial dysfunction Results: The results show that there were no...Department of Biological and Medical SciencesKatedra biologických a lékařských vědFarmaceutická fakulta v Hradci KrálovéFaculty of Pharmacy in Hradec Králov
Giants as Mythological Creatures in two Stories by Ivana Brlić - Mažuranić
No full textOvaj diplomski rad bazira se na dosadašnjim istraživanjima o divovima u kojima su opisane karakteristike divova kao mitoloških bića. Na temelju tih istraživanja su u ovom radu analizirani divovi u dvije bajke autorice Ivane Brlić – Mažuranić, a to su Regoč i Priča o Zorku Bistrozorkom i o Sreći. Većina autora koji su istraživali književni opus Ivane Brlić – Mažuranić uglavnom su pisali o utjecajima slavenske mitologije na njezinu inspiraciju, njezinim Pričama iz davnina i mitološkim bićima unutar njih, dok su divovi i ostala njezina djela u manjoj mjeri istražena. Svrha ovog rada je na temelju dosadašnje literature istražiti i opisati divove sa psihološkog aspekta te na taj način dati doprinos istraživanjima koja su vezana uz stvaralaštvo Ivane Brlić – Mažuranić. Divovi se kao bića pojavljuju u mnogim mitologijama diljem svijeta, ali su u svakoj od njih prikazani u različitim verzijama, a u ovom se preglednom radu opisuju karakteristike divova koje je autorica bajki prikazala na svoj jedinstven način. Bajke su analizirane sa psihološkog aspekta, a likovi su opisani na temelju Big Five teorije ličnosti.This master's thesis is based on previous research concerning giants in which the characteristics of giants as mythological creatures were described. Based on those studies, this work analyzes giants in two tales by Ivana Brlić – Mažuranić – Regoč and Priča o Zorku Bistrozorkom i o Sreći. Most authors who have written about the literary opus of Ivana Brlić – Mažuranić wrote mostly on the influences of Slavic mythology on her inspiration, her Tales of long ago and the mythological creatures within them, while giants and the rest of her literary works were somewhat less researched. This thesis focuses on researching and describing giants from a psychological aspect and, in that manner, contributes to previous research concerning Ivana Brlić – Mažuranić. Giants appear in numerous mythologies around the world, but each one of them presents a different version of the creature and this thesis describes the characteristic of giants as presented by author in her unique way. The tales have been analyzed from a psychological viewpoint and the characters have been described using the Big Five personality traits theory
Conclusioni
No full textL’unitarietà rigorosa e la vastità del complesso del Vantiniano, che fa provare a chi lo percorra un senso di piccolezza, di- mostra che Rodolfo Vantini ha tradotto in volumi di pietra bianca un’immagine mentale ricca di suggestioni emozionali e razionali al tempo stesso.
La potenza e la fascinazione del Vantiniano si manifestano proprio in questo ampio ventaglio di suggestioni visive e mentali, in questi svariati fil rouge che intrecciano i pensieri e le emozioni che hanno ispirato in Vantini l’immagine progettuale con quelli che affiorano in ciascuno di noi, quando entriamo in questa città
Clinical Characterization of a 6-Year-Old Patient with Autism and Two Adjacent Duplications on 10q11.22q11.23. A Case Report
No full textAutism is a neurodevelopmental disorder presenting in the first 3 years of life. Deficits occur in the core areas of social communication and interaction and restricted, repetitive patterns of behavior, interests or activities. The causes of autism are unknown, but clinical genetic studies show strong evidence in favor of the involvement of genetic factors in etiology. Molecular genetic studies report some associations with candidate genes, and candidate regions have emerged from several genome-wide linkage studies. Here, we report a clinical case of autism in a 6-year-old boy with double duplication on 10q11.22q11.23 with ASD (Autism Spectrum Disorder), intellectual disability, developmental delay, hypotonia, gross-motor skills deficit, overgrowth and mild dysmorphic features. In the literature, only five cases of ASD with 10q11.21q11.23 duplication are reported. This is the first extensive clinical description of an ASD subject with 10q11.22q11.23 duplication. Our findings suggest that 10q11.21q11.23 microduplication could represent a copy number variant that predisposes to autism
The role of nurses in managerial positions
No full textAnnotation: Title of the work: THE ROLE OF NURSES IN MANAGERIAL POSITIONS Author: Bališová Ivana Institution: Institute of Social Medicine LF UK in Hradec Králové, Department of Nursing Head of the work: Doc. PhDr. Jana Kutnohorská, CSc. Number of pages: 116 Number of attachments: 21 Year of the defense: 2010 Bachelor Thesis of title The Role of Nurses in managerial positions is composed in free parts: theoretical, empirical and attachments. It is aimed atclarifying the importance of the work of nurses in managements positions. There are important factors related to the leadership and their connection of nursing management area in the theoretical part. There are results of research survey in the practical part which investigates with intensity of nurse's work who are working at lower and middle level of management, identifies not only problems but also the motivating factors of their work. The supplement is the entire text of the questionnaire and materials related to this topic. The purpose of this work is also to highlight the work of nurses in managerial positions, which is very difficult, because they are an important interlink between the management of medical equipment and nurses at the lowest levels whose result of their work is evaluated by a satisfaction of the patient. Keywords: management,..
PHRASEOLOGY IN IVANA BRLIĆ-MAŽURANIĆ'S OPUS
No full textU radu se istražuje frazeologija na početku 20.stoljeća, koju je Ivana Brlić-Mažuranić ugradila u svoja najpoznatija prozna djela. Frazeologija je proučavana, i kao lingvistička disciplina koja proučava frazeme, i kao tehnika izražavanja svojstvena navedenoj književnici. Proučen je strukturni i semantički aspekt frazema te zaključeno kako je autoričina frazeologija razgovornoga stila.The paper focuses on the phraseology of the early 20th century, used by Ivana
Brlić-Mažuranić in her most famous prose works. Phraseology is observed from two
perspectives – as a linguistic discipline that studies phraseological units, and as a particular
manner of expression unique to the author herself. We have analyzed the structural and
semantic aspects of phraseological units, and concluded that her phraseology belongs to
conversational style
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