1,721,407 research outputs found
As TAVI Population Expands, More Studies of Permanent Pacemaker Implantation Are Needed
No full textAORTIC-VALVE IMPLANTATION; BUNDLE-BRANCH BLOCK; ATRIOVENTRICULAR-BLOCK; PREDICTOR
Rationale for the use of bioresorbable vascular scaffolds. Why bioresorbable technology is the future of endovascular therapeutics
No full textAncora in fase di pubblicazi
In-stent restenosis.
No full textEven after optimal immediate results, restenosis still occurs in a relevant percentage of patients after stent implantation. This disappointing outcome has strong clinical and socio-economical implications and has become a major target of research in cardiology. The conceptual difference between the mere resolution of the restenotic lesion and the understanding of the mechanisms of restenosis creates a dichotomy between daily practice in the catheterization laboratory and questions raised in the research laboratory that commonly divides people (clinicians and researchers) and budgets (industries and academic institutions). As a consequence, efforts are aimed at treating the consequences of unsuccessful stenting on the one hand, and to understand the causes of excessive neointimal proliferation on the other. However, the commitment of researchers and the large clinical experience accumulated in these years are by-products of the symbiosis between manufacturers and scientists, and it seems as though the fight against restenosis is about to be won with the further setting-up of adequate means that act effectively on the target, even though it has not been clearly understood or identified. Such a pragmatic position, although possibly effective, should remind us that the ancient peoples used natural medicines to cure diseases that they never understood
The need for this supplement: beyond "exercises in style"
No full textDuring the last 20 years, primary PCI has evolved from being an almost experimental intervention to becoming a routine job performed around the clock, as commonplace as a general surgeon operating on an acute appendicitis, or a traumatologist reducing an exposed fracture. At this point in time, the primary PCI technique has evolved from a simple, prudent inflation of balloons, to the administration of complex drug cocktails, routine implantation of stents, aggressive manipulation of thrombus, amazing intravascular imaging, and to concepts such as preconditioning and even recovering of dead myocardial tissue with cardiopoietic regenerative therapy
Experiences with primary angioplasty without on site-cardiac surgery.
No full textGrowing evidence suggests that primary angioplasty is superior to thrombolysis for the treatment of acute myocardial infarction, in particular in some high-risk subsets. The performance of primary angioplasty in centres without on-site cardiac surgery may extend the availability of this effective reperfusion therapy. This will benefit in particular those patients who would not be treated otherwise. Optimal primary angioplasty requires a high level of logistic organization, operator expertise, and commitment of the whole team. The outcome does not depend on the presence or absence of surgeons on site. In fact, feasibility, safety and efficacy of primary angioplasty are similar in both types of centres when high standards of care are guaranteed
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