10,992 research outputs found
Diurnal variation of analgosedation doses in mechanically ventilated patients including ECMO: a single centre observational cohort study
No full textDiurnal variation of analgosedation doses in mechanically ventilated patients including ECMO: a single centre observational cohort study
No full textSupplemental Material - Methadone as an opioid and sedative weaning strategy in adults receiving extracorporeal membrane oxygenation
No full textSupplemental Material for Methadone as an opioid and sedative weaning strategy in adults receiving extracorporeal membrane oxygenation by Christopher Remmington, Victor Liew, Fraser Hanks, Luigi Camporota, Oliver Stubbs, Angelo Sousa, and Nicholas A Barrett in Perfusion</p
Interview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American City
No full textInterview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American Cit
Extracorporeal membrane oxygenation and diurnal analgosedation:A comparative retrospective study in ventilated patients
No full textBackground: Diurnal variation of analgosedation may worsen patient outcomes. However, there is no data reporting diurnal variation in patients receiving extracorporeal membrane oxygenation (ECMO). Objectives: To compare diurnal variation of analgosedation doses in mechanically ventilated adult patients and those receiving ECMO. Setting: Five ICUs (65 beds) including an ECMO unit, with patient recruitment from July 2021 to July 2023. Methods: Retrospective single-centre cohort study including patients aged ≥ 16 years receiving continuous intravenous (IV) opioid (fentanyl) and/or sedative (midazolam and/or propofol), receiving mechanical ventilation with or without ECMO. We collected data on all intravenous analgosedation doses (excluding boluses) from 07:00 to 18:59 (day) or from 19:00 to 06:59 (nighttime) for 48 h. Results: We identified 1277 patients; of whom 166 (13.0 %) received ECMO and 1111 (87.0 %) received no ECMO. Most were male 815 (63.8 %), median (interquartile range (IQR)) age 58 (42–70) years. We found no diurnal variation of analgosedation doses in ECMO patients. However, we found higher doses of fentanyl (mean difference 1.7 µg/kg, 95 % Confidence Interval (CI): 1.0, 2.4 μg/kg, p < 0.001) and propofol (mean difference 2.3 mg/kg, 95 % CI: 1.7, 2.9 mg/kg, p < 0.001) at nighttime compared to daytime in non-ECMO patients. A higher proportion of ECMO patients received neuromuscular blocking drugs compared to non-ECMO group 120 (72.3 %) vs 138 (12.4 %); p < 0.001. Conclusions: We found higher doses of fentanyl and propofol IV infusion doses at nighttime in non-ECMO patients. However, we found no diurnal variation of analgosedation doses in ECMO patients, most likely due to deep sedation and use of neuromuscular blocking medicines. Implications for clinical practice: Patient factors, critical illness factors and type of ICU admission are likely contributory factors to differences in diurnal variation of analgosedation doses in ECMO and non-ECMO populations.</p
Matt Christopher Papers - Accession 1309
No full textThe collection includes letters written by the children’s book author, Matt Christopher, to his son, Marty Christopher. Many of the letters also contain newspaper articles of interest to Matt Christopher, which deal with local sports teams, his writing career, his participation in an exhibition baseball game against the New York Giants in 1938, and other of general interest. Most of the letters are personal in nature, however, a majority of the letters delve into Matt Christopher’s writing career, personal interests, the author’s health, as well as his family life.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/2649/thumbnail.jp
Matt Christopher Papers - Accession 1221
No full textMatt Christopher (1917-1997) was a prolific author of children’s books having written over 100 books as well as over 300 short stories, articles, poems, and screenplays. Most of his writings dealt with sports themes, but he also wrote fantasy and mystery themed stories as well. The Matt Christopher Papers consist of both published and unpublished manuscripts, articles, and short stories. Also included are personal and business correspondence, biographical information, scrapbooks, photographs, and memorabilia.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/1976/thumbnail.jp
Dr. Christopher von Rueden – Faculty Author Interview
No full textDr. Christopher von Rueden, an anthropologist and Assistant Professor in the Jepson School of Leadership Studies, discusses a recent article entitled, “Men’s status and reproductive success in 33 non-industrial societies: Effects of subsistence, marriage system, and reproductive strategy,” which he co-authored with Dr. Adrian Jaeggi, an anthropologist at Emory University. Their findings were recently published in the journal, Proceedings of the National Academy of Sciences
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