3,197 research outputs found
Thermomorphogenesis: Opportunities and challenges in posttranscriptional regulation.
No full textPlants exposed to mildly elevated temperatures display morphological and developmental changes collectively termed thermomorphogenesis. This adaptative process has several undesirable consequences to food production, including yield reduction and increased vulnerability to pathogens. Understanding thermomorphogenesis is, thus, critical for understanding how plants will respond to increasingly warmer temperature conditions, such as those caused by climate change. Recently, we have made major advances in that direction, and it has become apparent that plants resource to a broad range of molecules and molecular mechanisms to perceive and respond to increases in environmental temperature. However, most of our efforts have been focused on regulation of transcription and protein abundance and activity, with an important gap encompassing nearly all processes involving RNA (i.e., posttranscriptional regulation). Here, I summarized our current knowledge of thermomorphogenesis involving transcriptional, posttranscriptional, and posttranslational regulation, focused on opportunities and challenges in understanding posttranscriptional regulation-a fertile field for exciting new discoveries
Recommended from our members
CRISPR/Cas to enhance gene expression for crop trait improvement by editing miRNAs targets.
No full textArticle states that gene editing tools such as CRISPR/Cas9 are often thought of as a means to prevent gene expression; however, a more subtle and yet powerful approach is the enhancement of gene expression by precise deletion of repressor sites within a gene of interest. Authors argue that gene editing of miRNA target sites is preferable over deletion of the miRNA genes themselves, given that it avoids the pitfalls of unspecific derepression of miRNA target(s) beyond the gene of interest
A necrópole do século XVI instalada na Villa romana do Rabaçal
No full textSilva, A.M.; Carnim, G.; Isidoro, J.; Reis, M.; Matos, V.; Marques, A.C. 2001. A necrópole do século XVI instalada na Villa romana do Rabaçal. In: M. Pessoa; L. Rodrigo; S. Santos (Eds.). Roteiro: Rabaçal - Aldeia Cultural. Penela: Câmara Municipal de Penela, pp. 20-22. ISBN: 972-97881-1-
Quadros provincianos : a obra de Rodrigo Júnior
No full textOrientador: Prof. Dr. Rodrigo Vasconcelos MachadoTese (doutorado) - Universidade Federal do Paraná, Setor de Ciências Humanas, Programa de Pós-Graduação em Letras. Defesa : Curitiba, 21/08/2019Inclui referências: p. 342-348Resumo: O objetivo geral desta tese é reunir e analisar a obra do poeta paranaense Rodrigo Júnior, pseudônimo de João Baptista Carvalho de Oliveira (1887-1964). Para isso, foi necessário coletar a quantidade máxima das suas publicações literárias e ensaísticas e, num recorte específico, analisá-las e discuti-las sob a perspectiva de quanto seus textos se apresentam como provincianos, e, quanto ao mesmo tempo não os são. Rodrigo Júnior é um autor que buscou intensamente seu próprio estilo no meio do confuso pré-modernismo, entre o parnasianismo, simbolismo e o neorromantismo, utilizando-se de várias estéticas e escolas unicamente com objetivo encontrar sua liberdade na arte. Nessa busca, encontrou a sua voz quando escreveu principalmente seus poemas com temas bucólicos, amorosos, satíricos, quase sempre atravessados por uma constante melancolia, por um tédio e pessimismo, uma tristeza de quem deseja paz e felicidade. Consagrou-se como poeta de rara qualidade, compondo ora em formas clássicas, ora em verso livre sempre com uma linguagem simples, mas também foi um eficiente prosador, como escritor de contos, crônicas, novelas e ensaios. Sua carreira começa no início do século XX e dura até os anos 60, atuando diariamente na imprensa curitibana, estabelecendo-se como um agitador cultural durante esse tempo. A produção gigantesca contrasta com seus poucos livros publicados, pois acabou abandonando muitos projetos de livros e deixando a maior parte dos seus escritos esparsos em jornais e revistas. Incentivou e influenciou pelo menos duas gerações de artistas do Paraná, como os jovens interessados no futurismo e no modernismo e os literatos da década de 30 e 40 que queriam modernizar as letras paranaenses. Por fim, dedicou boa parte da sua vida à literatura e à criação um sistema literário no Paraná autossuficiente que fosse independente dos grandes centros urbanos da época como o Rio de Janeiro. Palavras-chave: Rodrigo Júnior. Literatura paranaense. Pré-modernismo e modernismo paranaense. Simbolismo. Provincianismo.Abstract: The general objective of this thesis is to gather and analyze the work of the poet Rodrigo Júnior, pseudonym of João Baptista Carvalho de Oliveira (1887-1964). For this, it was necessary to collect the maximum amount of their literary and essayistic publications and, in a specific cut, to analyze and discuss them from the perspective of how much their texts are provincial, and at the same time not. Rodrigo Júnior is an author who intensely sought his own style in the midst of confusing pre-modernism, between parnasianism, symbolism and neorromantism, using various aesthetics and schools solely to find their freedom in art. In this search, he found his voice when he wrote mainly his poems with bucolic, loving, satirical themes, almost always crossed by a constant melancholy, boredom and pessimism, a sadness of those who want peace and happiness. He established himself as a poet of rare quality, composing sometimes in classical forms, sometimes in free verse always with simple language, but was also an efficient prospector, as a writer of short stories, chronicles, novels and essays. His career begins in the early twentieth century and lasts until the 1960s, working daily in the Curitiba press, establishing himself as a cultural agitator during that time. The mammoth production contrasts with its few published books, as it has abandoned many book projects and left most of its sparse writings in newspapers and magazines. It encouraged and influenced at least two generations of artists from Paraná, such as the young people interested in futurism and modernism and the literati of the 30's and 40's who wanted to modernize Paraná's lyrics. Finally, he devoted much of his life to literature and the creation of a self-sufficient literary system in Paraná that was independent of the great urban centers of the time such as Rio de Janeiro. Keywords: Rodrigo Júnior. Literature from Paraná. Premodernism and modernism of Paraná. Simbolism. Provincialism
¿Hay alguien allí? Metaficción en La velocidad de las cosas, de Rodrigo Fresán
No full textIs there anybody? Metafiction in Rodrigo Fresán’s The Speed of Things In this article we attempt to present a wide spectrum of metafictional techniques used in Rodrigo Fresán’s The Speed of Things. The book, constructed on the principle of hybridisation, fuses various devices of the metanarrative frame stories, fractal construction, fictionalization of writing as an act of creation, self-consciousness of narrators and the metadiscourse figure of the writer identified with the real author, literary reflection in order to form a complex metafictional game that invites the reader to participate in the literary dialogue. Is there anybody? Metafiction in Rodrigo Fresán’s The Speed of Things In this article we attempt to present a wide spectrum of metafictional techniques used in Rodrigo Fresán’s The Speed of Things. The book, constructed on the principle of hybridisation, fuses various devices of the metanarrative frame stories, fractal construction, fictionalization of writing as an act of creation, self-consciousness of narrators and the metadiscourse figure of the writer identified with the real author, literary reflection in order to form a complex metafictional game that invites the reader to participate in the literary dialogue. 
Historia de la muerte y glorioso martyrio del sancto Innocente, que llaman de la Guardia, natural de la ciudad de Toledo ... : con otros tractados de mucha doctrina y preouecho, que son los de la plana siguiente
No full textEl pie de imp. consta en colofón, en v. de h. 78 y de h. 96 de la primera secuencia de fol.Colofón en v. de h. 43 y de h. 88 de la segunda secuencia de fol.Sign.: ¶\p10\s, A-M\p8\s, ¶\p4\s ; A-L\p8\s, O\p3\s.Ports. con grab xil.Ilustraciones xil.Contiene: Tractado y platica de la ciudad de Toledo a sus vezinos afligidos .../author el maestro Alexio Venegas de Busto ; corregido por ... Rodrigo de Yepes ..., de h. 79 a 96 de la primera secuencia de fol. ; Tractado y descripcion breue y c¯opendiosa de la tierra sancta de Palestina ..., h. 1-43 de de la segunda secuencia de fol., con port. propia ; Tractado de la peregrinacion que Iesu Christo ... hizo en este mundo, h. 44-88 de la segunda secuencia de fol
Missing pieces in the puzzle of plant microRNAs
No full textPlant microRNAs (miRNAs) are important regulatory switches. Recent advances have revealed many regulatory layers between the two essential processes, miRNA biogenesis and function. However, how these multilayered regulatory processes ultimately control miRNA gene regulation and connects miRNAs and plant responses with the surrounding environment is still largely unknown. In this opinion article, we propose that the miRNA pathway is highly dynamic and plastic. The apparent flexibility of the miRNA pathway in plants appears to be controlled by a number recently identified proteins and poorly characterized signaling cascades. We further propose that altered miRNA accumulation can be a direct consequence of the rewiring of interactions between proteins that function in the miRNA pathway, an avenue that remains largely unexplored
Correction to: Long-term changes in rainfed olive production, rainfall and farmer’s income in Bailén (Jaén, Spain) (Euro-Mediterranean Journal for Environmental Integration, (2021), 6, 2, (58), 10.1007/s41207-021-00268-1)
No full textThe article Long‐term changes in rainfed olive production, rainfall and farmer’s income in Bailén (Jaén, Spain), written by Jesús Rodrigo‐Comino, José María Senciales‐Gonzalez, Yang Yu, Luca Salvati, Antonio Gimenez‐Morera and Artemi Cerdà, was originally published electronically on the publisher’s internet portal on 18 June 2021 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on 3 July 2021 to © The Author(s) 2021 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creat iveco mmons. org/ licen ses/ by/4.0. The original article has been corrected
Gene regulation by translational inhibition is determined by Dicer partnering proteins
No full textMicroRNAs (miRNAs) are small regulatory RNAs produced by Dicer proteins that regulate gene expression in development and adaptive responses to the environment1,2,3,4. In animals, the degree of base pairing between a miRNA and its target messenger RNA seems to determine whether the regulation occurs through cleavage or translation inhibition1. In contrast, the selection of regulatory mechanisms is independent of the degree of mismatch between a plant miRNA and its target transcript5. However, the components and mechanism(s) that determine whether a plant miRNA ultimately regulates its targets by guiding cleavage or translational inhibition are unknown6. Here we show that the form of regulatory action directed by a plant miRNA is determined by DRB2, a DICER-LIKE1 (DCL1) partnering protein. The dependence of DCL1 on DRB1 for miRNA biogenesis is well characterized7,8,9, but we show that it is only required for miRNA-guided transcript cleavage. We found that DRB2 determines miRNA-guided translational inhibition and represses DRB1 expression, thereby allowing the active selection of miRNA regulatory action. Furthermore, our results reveal that the core silencing proteins ARGONAUTE1 (AGO1) and SERRATE (SE) are highly regulated by miRNA-guided translational inhibition. DRB2 has been remarkably conserved throughout plant evolution, raising the possibility that translational repression is the ancient form of miRNA-directed gene regulation in plants, and that Dicer partnering proteins, such as human TRBP, might play a similar role in other eukaryotic systems
Historia de la muerte y glorioso martyrio del sancto Innocente, que llaman de la Guardia, natural de la ciudad de Toledo ... : con otros tractados de mucha doctrina y preouecho, que son los de la plana siguiente
No full textEl pie de imp. consta en colofón, en v. de h. 78 y de h. 96 de la primera secuencia de folColofón en v. de h. 43 y de h. 88 de la segunda secuencia de folSign.: ¶\p10\s, A-M\p8\s, ¶\p4\s ; A-L\p8\s, O\p3\sPorts. con grab xilIlustraciones xilContiene: Tractado y platica de la ciudad de Toledo a sus vezinos afligidos .../author el maestro Alexio Venegas de Busto ; corregido por ... Rodrigo de Yepes ..., de h. 79 a 96 de la primera secuencia de fol. ; Tractado y descripcion breue y c¯opendiosa de la tierra sancta de Palestina ..., h. 1-43 de de la segunda secuencia de fol., con port. propia ; Tractado de la peregrinacion que Iesu Christo ... hizo en este mundo, h. 44-88 de la segunda secuencia de fol
- …
