757 research outputs found
cexA and its regulatory processes - the manganese mistery of A. niger
cexA and its regulatory processes – a closer look into the citric acid production
mechanisms of Aspergillus niger
Authors: Aline Reinfurt, Valeria Ellena, Matthias G. Steiger
Aspergillus niger is an important filamentous fungus used for the industrial production
of citric acid. One of the main contributors to high citric acid accumulation by the
fungus is the citrate transporter CexA. It belongs to the major faciliatory superfamily
subclass DHA1 which act as drug-H+ antiporters1. Since cexA and its regulators are
essential within the citric acid production process, it is important to study their
regulatory mechanism, which is the focus of this work. LaeA for one is known to be a
major regulator of the cexA gene. It regulates the expression via methylation levels of
the histones H3K4 and H3K92. There are indications that other transcriptional
regulators such as AmyR and XlnR are also involved in the regulation of cexA on a
transcriptional level. Another factor that affects citric acid production is the amount of
manganese that is present during the production process. Observations showed that
the fungus develops a certain pellet-like morphology under manganese limitation
conditions and that this limitation is decisive for high citric acid accumulation by A.
niger3,4. However, the exact mode of action of manganese in the cell is not clear. The
transcriptional influence of manganese on cexA and laeA is investigated in order to
find out more about the connection between manganese limitation and citric acid
production
cexA and its regulatory processes - the manganese mistery of A. niger
cexA and its regulatory processes – a closer look into the citric acid production
mechanisms of Aspergillus niger
Authors: Aline Reinfurt, Valeria Ellena, Matthias G. Steiger
Aspergillus niger is an important filamentous fungus used for the industrial production
of citric acid. One of the main contributors to high citric acid accumulation by the
fungus is the citrate transporter CexA. It belongs to the major faciliatory superfamily
subclass DHA1 which act as drug-H+ antiporters1. Since cexA and its regulators are
essential within the citric acid production process, it is important to study their
regulatory mechanism, which is the focus of this work. LaeA for one is known to be a
major regulator of the cexA gene. It regulates the expression via methylation levels of
the histones H3K4 and H3K92. There are indications that other transcriptional
regulators such as AmyR and XlnR are also involved in the regulation of cexA on a
transcriptional level. Another factor that affects citric acid production is the amount of
manganese that is present during the production process. Observations showed that
the fungus develops a certain pellet-like morphology under manganese limitation
conditions and that this limitation is decisive for high citric acid accumulation by A.
niger3,4. However, the exact mode of action of manganese in the cell is not clear. The
transcriptional influence of manganese on cexA and laeA is investigated in order to
find out more about the connection between manganese limitation and citric acid
production
When Opposites Attract: Moral Polarity in Sade’s 'Aline et Valcour'
Sade is often seen as an author who wishes to convey a particular view of the world in his novels. It is well known that in life he passionately embraced a philosophy that was at once monist-materialist and libertine. This article explores the curious fact that it is difficult to locate a corresponding ‘message’ in Aline et Valcour, which is subtitled Le roman philosophique. One important reason for this is the influence of Richardson’s Clarissa. Both novels are built around an opposition between the supporters of two ‘camps’: Christian virtue and libertinage. In Aline et Valcour no less than in Clarissa, these camps are prepared to fight to the death. But in each of these novels, too, the opposition is not a straightforward one, for it has a symbiotic aspect. The libertines need the virtuous in order to achieve their goal of desecrating, and so symbolically defeating, the Christian view of the world. But the virtuous also need their libertine persecutors if they are to achieve the feats of moral suffering, associated with sensibilité, that constitute their highest aim. In brief, Aline et Valcour obeys a Richardsonian aesthetic in which each side is allowed to fight its cause without being definitively supported or undermined by the (implied) author. This helps to explain why, considered as a ‘philosophical novel’, it seems heuristic rather than dogmatic
Loaisel de Tréogate, romancier féministe ?
Aline Jalliet : Was Loaisel de Treogate a feminist ?
Women occupy a central position in the novels of Loaisel de Tréogate (1752-1812) and in his heroes' adventures. Although the author often expresses traditional male chauvinist prejudices, he also goes beyond this conventional view by presenting couples in which true exchange between the partners is essential to the man's happiness. In addition, the woman is given a subversive discourse that, by uncovering man's age-old usurpation, is the first shot in a necessary war of the sexes. He is, thanks to his belief in equality, a novelist of the mythical, fraternal married couple, but his attempts to define the essence and the role of women link him to 18th-century debates on women's identity and place in society.Jalliet Aline. Loaisel de Tréogate, romancier féministe ?. In: Dix-huitième Siècle, n°26, 1994. Economie et politique. pp. 475-485
De « La Vieille Henriette » à Aline : ethnogénétique d’une filiation et d’une affiliation
The recent discovery of the manuscript “La Vieille Henriette”, Ramuz’ completed but unpublished novel, dated March 9-May 5, 1904, calls for a re-examination of the “avant-texts” of Aline, started in the summer of 1904. Indeed, the eponymous character of the unpublished novel reappears with the same name as a protagonist in the “Manuscript 1” of Aline, and is still present in the original April 1905 edition, while losing most of her narrative efficiency. The three “avant-textes” (“La Vieille Henriette”, “Manuscript 1” and “Definitive Manuscript” of Aline) are narrative places where the author experiments with the fictional representation of economic and symbolic exchanges. The variations found (the movements of bodies, goods and speeches) are critical points for a world whose culture is changing, specially when the rules are rejected of transgressed
When Do Children Dislike Ingroup Members? Resource Allocation from Individual and Group Perspectives
Do children like ingroup members who challenge group norms about resource allocation? Further, do children evaluate from their own individual perspective? Participants (N = 381), aged 9.5 and 13.5 years, evaluated members of their own group who deviated from group norms about resource allocation by either: (1) advocating for equal allocation in contrast to the group norm of inequality; or (2) advocating for inequality when the group norm was to divide equally. With age, participants differentiated their own individual favorability from the group's favorability of deviant members of the ingroup. Further, when deciding between group loyalty and equal allocation, children and adolescents gave priority to equality, rejecting group decisions to dislike ingroup members who advocated for equality
Pequena coreografia da mulher selvagem: o amadurecimento feminino na Pequena coreografia do adeus, de Aline Bei
This article tries to interpret the novel Pequena coreografia do Adeus (2021), by Aline Bei, in the light of psychoanalysis, considering, for that purpose, the theories related to the female psyche elaborated in Women who run with the wolves, in which the author, Clarissa Pinkola Estés, influenced by the works of C. G. Jung, explores the myths and stories of the “Wild Woman” archetype. Although this is just one interpretation among the possible ones, Estés’ work proves to be an interesting reading guide, as it not only contributes to the understanding of relevant aspects of Aline Bei’s book – once Pequena coreografia do Adeus revisits, with its very particular style, several recurrent elements in literature –, but offers as well a psychoanalytic look at the understanding of female authorship.O presente artigo busca interpretar o romance Pequena coreografia do Adeus (2021), de Aline Bei, à luz da psicanálise, movimentando, para tanto, as teorias relativas à psique feminina elaboradas em Mulheres que correm com os lobos, trabalho no qual a autora, Clarissa Pinkola Estés, influenciada pelos trabalhos de C. G. Jung, explora os mitos e histórias do arquétipo da “Mulher Selvagem”. Apesar de essa ser apenas uma interpretação entre as possíveis, a obra de Estés se mostra um guia de leitura interessante, pois não apenas colabora para a compreensão de aspectos relevantes da obra de Aline Bei – à medida que a Pequena coreografia do Adeus revisita, com seu estilo tão particular, diversos elementos recorrentes na literatura –, como também oferece um olhar psicanalítico para a compreensão da autoria feminina
Mangan(II)-Ionen und ihre regulatorische Wirkung auf die Zitronensäureproduktion in Aspergillus niger
Ruins of the past: the use and perception of abandoned structures in the Maya lowlands
Travix W. Stanton and Aline Magnoni, editors.Includes bibliographical references and index.From the Formative to the present, Maya peoples have continuously built, altered, abandoned, and re-used structures, imbuing them with new meanings at each transformation. Ruins of the Past is the first volume to focus on how previously built structures in the Maya Lowlands were used and perceived by later peoples, exploring the topic through concepts of landscape, place, and memory.--Book jacket.Foreword / Wendy Ashmore -- Places of remembrance: the use and perception of abandoned structures in the Maya lowlands / Travis W. Stanton and Aline Magnoni -- Forgotten structures, haunted houses, and occupied hearts: ancient perspectives and contemporary interpretations of abandoned sites and buildings in the Mirador Basin, Guatemala / Richard D. Hansen, Wayne K. Howell, and Stanley P. Guenter -- The transformation of abandoned architecture at Piedras Negras / Mark B. Child and Charles W. Golden -- Structure abandonment and landscape transformation: examples from the Three Rivers region / Lauren A. Sullivan [and others] -- Manipulating memory in the wake of dynastic decline at El Perú-Waka': termination deposits at abandoned structure M13-1 / Olivia C. Navarro Farr, David A. Freidel, and Ana Lucía Arroyave Prera -- Establishing and reusing sacred place: a diachronic perspective from Blackman Eddy, Belize / M. Kathryn Brown and James F. Garber -- Anatomy of a post-collapse society: identity and interaction in early postclassic Copán / T. Kam Manahan -- Landscape transformations and changing perceptions at Chunchucmil, Yucatán / Aline Magnoni, Scott R. Hutson, and Travis W. Stanton -- Edzná: a lived place through time / Antonio Benavides C. -- Memories, meanings, and historical awareness: post-abandonment behaviors among the lowland Maya / Marcello A. Canuto and Anthony P. Andrews -- Afterword / Denise Fay Brown
Correction to: Rate and determinants of non-adherence to a gluten-free diet and nutritional status assessment in children and adolescents with celiac disease in a tertiary Brazilian referral center: a cross-sectional and retrospective study
Correction
Unfortunately, after publication of this article [1], it was noticed that the names of the second and third authors were incorrectly displayed, respectively, as Glauce Hiromi Yonaminez and Carla Aline Satiro. The correct names are Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro and can be seen in the corrected author list above. The original article has also been updated to correct this error
- …
