96 research outputs found
Platygaster lamelliformis Huggert 1973
No full textPlatygaster lamelliformis Huggert, 1973 England: Devon, Newton Abbot, 1 female, 12 September 1977, canal, det. D. Notton, 2005 (BMNH); Oxfordshire, Wytham, 1 female, 19 July 1953, Graham, M.W.R. de V., det. D. Notton, 2006 (BMNH); Surrey, Bookham, 1 female, 26 June 1932, Nixon, G.E.J., det. D. Notton, 2005 (BMNH); Surrey, Bookham, 2 females, 5 July 1942, Blood, B.N., det. D. Notton, 2006 (BMNH); Oxfordshire, Oxford, 1 female, 18 May 1970, Bou C ek, Z. (BMNH). Scotland: Stirling, Killin, 1 female, 1 July 1953, marsh or pond, Graham, M.W.R. de V., det. D. Notton, 2006 (BMNH). Wales: Anglesey, Cors Bodeilio, SH503776, 1 female, 26 July 1988, Molinia caerulea / Potentilla erecta mire, Boyce, D.C., Holmes, P.R. and Reed, D.K., det. D. Notton, 2001 (DGN). First recorded from the British Isles by Notton (2006).Published as part of Buhl, Peter N. & Notton, David G., 2009, A revised catalogue of the Platygastridae of the British Isles (Hymenoptera: Platygastroidea), pp. 1651-1703 in Journal of Natural History 43 (27 - 28) on pages 1678-1679, DOI: 10.1080/00222930902993732, http://zenodo.org/record/521661
The role of surgery in the treatment of older women with breast cancer
No full textA significant proportion of women diagnosed with breast cancer are over the age of 70 years and there is evidence that these patients frequently do not receive standard treatments, including surgical procedures and adjuvant therapies, which would be routine practice in younger age groups. The factors underlying this may include the physiological effects of ageing, differences in the biology and stage of the tumour at presentation, patient co-morbidities and patient and clinician preferences. The interaction of all these factors needs to be considered when individualising treatment plans for patients. For some patients this will need to be undertaken in the context of an extended multidisciplinary team setting with additional input from geriatricians, in addition to surgeons and oncologists, in defining a treatment plan. Little is known about the preferences of older patients in their choice of surgical treatment for breast cancer and further research is required to increase the evidence base for the rational management of older women with breast cancer
The role of nitric oxide in the treatment of tumours with aminolaevulinic acid-induced photodynamic therapy
No full textPrognostic significance of angiogenesis in transitional cell carcinoma of the human urinary bladder
No full textDifferential cell death response to photodynamic therapy is dependent on dose and cell type
No full textPDT-induced cell death, by either apoptosis or necrosis may vary with cell type or PDT dose. 5 cell types were treated with varying doses of aminolaevulinic acid-induced PDT and the type of cell death analysed. The mode of cell death was found to depend on both cell type and light dose. © 2001 Cancer Research Campaig
Leucocyte interactions with the mouse cremaster muscle microcirculation in vivo in response to tumour-conditioned medium
No full textLeucocyte interactions with the cremaster muscle microcirculation in vivo were investigated in response to culture medium conditioned with different cell types in 25 adult male Swiss mice. Animals were divided into five groups. Three groups received ex vivo fluorescently labelled lymphokine activated killer (LAK) cells systemically and had either tumour (murine melanoma K1735)-conditioned medium (TCM), fibroblast (murine 3T3)-conditioned medium (FCM) or fresh culture medium administered topically to the cremaster muscle. In the two remaining groups, the host leucocytes were labelled fluorescently by systemic administration of acridine red, and either TCM or FCM was applied topically to the cremaster muscle. There was an immediate but transient increase in the frequency of rolling and adherent LAK cells, and a subsequent (90-120 min later) increase in rolling and adherent host leucocytes, demonstrating temporal differences in the response to topical administration of TCM. These increases in contact with the vascular endothelium occurred in all vessel types, venules, arterioles and capillaries, with the greatest response observed in the venules. The FCM and normal culture medium did not affect the distribution and localization of either LAK cells or host leucocytes. These data suggest that there are one or more soluble tumour-specific chemoattractants for leucocytes present in the conditioned medium. The mouse cremaster muscle microcirculation is therefore a useful model to investigate the mechanism of leucocyte-endothelium interactions in tumour biology
Angiopoietin-1, angiopoietin-2 and Tie-2 receptor expression in human dermal wound repair and scarring
No full textAnopedias lacustris Kieffer 1926
No full text<i>Anopedias lacustris</i> Kieffer, 1926 <p>England: Norfolk, Strumpshaw Bird Reserve, TG338064, 1 female, 27 June 1989, Foster, A.P. and Procter, D.A., det. D. Notton, 2007 (DGN). Norfolk, Thompson Common, TL935965, 1 female, 10–24 June 1988, Foster, A.P. and Procter, D.A., det. D. Notton, 2007 (DGN).</p> <p>Scotland: Perth and Kinross, Birks of Aberfeldy, 4 females, 14 July 1977, Noyes, J.S., Rogers, L. and Huddleston, T. (BMNH); Perth and Kinross, Lawers PM, 1 female, 19 July 1952, Graham, M.W.R. de V. (BMNH); Perth and Kinross, Rannoch Forest, 4 females and 9 males, 13 July 1977, Noyes, J.S., Rogers, L. and Huddleston, T. (BMNH).</p> <p> Wales: Gwynedd, Arthog Bog, SH638149, 1 female, 23 June 1988, <i>Molinia caerulea / Potentilla erecta</i> mire, Boyce, D.C., Holmes, P.R. and Reed, D.K., det. D. Notton, 2007 (DGN); Newport, Langstone Meadows, ST382897, 4 females, 21 July 1988, <i>Molinia caerulea / Potentilla erecta</i> mire, Boyce, D.C., Holmes, P.R. and Reed, D.K., det. D. Notton, 2007 (DGN); Powys, Colwyn Brook Marshes, SO088542, 1 female, 18 July 1989, <i>Carex acutiformis</i> swamp, Boyce, D.C., Holmes, P.R. and Reed, D.K., det. D. Notton, 2007 (DGN).</p> <p>Recorded from Ireland by O’Connor et al. (2004), and from the Isle of Man by Buhl and Bennett (2009).</p>Published as part of <i>Buhl, Peter N. & Notton, David G., 2009, A revised catalogue of the Platygastridae of the British Isles (Hymenoptera: Platygastroidea), pp. 1651-1703 in Journal of Natural History 43 (27 - 28)</i> on pages 1655-1656, DOI: 10.1080/00222930902993732, <a href="http://zenodo.org/record/5216619">http://zenodo.org/record/5216619</a>
The effect of aminolaevulinic acid-induced, protoporphyrin IX-mediated photodynamic therapy on the cremaster muscle microcirculation in vivo
No full textThe effect of photodynamic therapy on normal striated muscle was investigated using 30 adult male rats. Animals were divided into six groups. Three control groups received phosphate-buffered saline by gavage and violet light at 105, 178 and 300 mW cm-2 respectively. Three experimental groups received aminolaevulinic acid (ALA; 200 mg kg-1) and violet light at 105, 178 and 300 mW cm-2 respectively. After exposure of the cremaster muscle animals were allowed to equilibrate and vessel diameters and bloodflow assessed. Following photoactivation measurements were taken every 10 min over a 2 h period. Photoactivation of experimental groups at the two higher power densities resulted in an initial decrease in both arteriolar and venular diameters, and a concomitant decrease in blood flow. The magnitude of these changes and the degree of recovery by the end of the observation period was related to power density. No effects were observed in the control groups. These results suggest that microcirculatory damage may contribute to the mechanism of action of photodynamic therapy with ALA
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