498 research outputs found
Sigmund Freud contra Helga Grebing - Kommentierende Anmerkungen zu den Beiträgen von Max Bloch, Karsten Rudolph, Meik Woyke und Walter Mühlhausen
No full textConcentrating on the contributions of Max Bloch, Karsten Rudolph, Meik Woyke and Walter Mühlhausen the author sums up the contributions of this volume in order to reflect on the current state of research in the field of the historiography of biographies of leading social democrats. He discusses remaining lacunae in research and develops perspectives for future research
A Novel Approach for Non-Invasive Continuous In-Line Control of Perfusion Cell Cultivations by Raman Spectroscopy
No full textContinuous manufacturing is becoming more important in the biopharmaceutical industry. This processing strategy is favorable, as it is more efficient, flexible, and has the potential to produce higher and more consistent product quality. At the same time, it faces some challenges, especially in cell culture. As a steady state has to be maintained over a prolonged time, it is unavoidable to implement advanced process analytical technologies to control the relevant process parameters in a fast and precise manner. One such analytical technology is Raman spectroscopy, which has proven its advantages for process monitoring and control mostly in (fed-) batch cultivations. In this study, an in-line flow cell for Raman spectroscopy is included in the cell-free harvest stream of a perfusion process. Quantitative models for glucose and lactate were generated based on five cultivations originating from varying bioreactor scales. After successfully validating the glucose model (Root Mean Square Error of Prediction (RMSEP) of ∼0.2 g/L), it was employed for control of an external glucose feed in cultivation with a glucose-free perfusion medium. The generated model was successfully applied to perform process control at 4 g/L and 1.5 g/L glucose over several days, respectively, with variability of ±0.4 g/L. The results demonstrate the high potential of Raman spectroscopy for advanced process monitoring and control of a perfusion process with a bioreactor and scale-independent measurement method
B --> ([rho]/[omega]) [gamma] at BaBar
No full textThesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 2007.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.In title on title page, "[right arrow] appears as the symbol; and "[rho]", "[omega]" and "[gamma]" appear as lower-case Greek letters.Includes bibliographical references (leaves 203-205).This document describes the measurements of the branching fractions and isospin violations of the radiative electroweak penguin decays B [right arrow] ([rho]/[omega]) [gamma] at the asymmetric energy e+e- PEP-II collider with the BABAR detector. Together with the previously measured branching fractions of the decays ... the ratio of CKM-matrix elements Vtd=Vts are extracted and the length of the far side of the unitarity triangle is determined.by Karsten Köneke.Ph.D
Comparative Raman study of transparent and turbid materials : models and experiments in the remote sensing mode
No full textThe influence of turbidity on the Raman signal strengths of condensed matter is theoretically analyzed and measured with laboratory - scale equipment for remote sensing. The results show the quantitative dependence of back- and forward-scattered signals on the thickness and elastic-scattering properties of matter. In the extreme situation of thin, highly turbid layers, the measured Raman signal strengths exceed their transparent analogs by more than a factor of ten. The opposite behavior is found for thick layers of low turbidity, where the presence of a small amount of scatterers leads to a decrease of the measured signal. The wide range of turbidities appearing in nature is experimentally realized with stacked polymer layers and solid/liquid dispersions, and theoretically modeled by the equation of radiative transfer using the analytical diffusion approximation or random walk simulations
Optofluidics
No full textThis introduction into the multidisciplinary area of optofluidics offers the necessary foundations in photonics, polymer physics and process analytics to students, engineers and researchers to enter the field. All basic ingredients of a polymer-based platform as a foundation for quick and compact solutions for chemical, biological and medical sensing and manipulation are developed
The Governance of Global Industry Associations:The Role of Micro-Politics
No full textThis insightful book examines the role of micro-politics in the life of global industry associations. Karsten Ronit addresses the various rules and norms required to administer these associations, highlighting the importance of managing variations in complex member demands and responding to expectations in their institutional environment. Posing a variety of empirical and theoretical challenges, the author charts the state of the art in the study of industry associations, evaluating the current condition of research in the field. Ronit offers a systematic approach to the role of global industry associations, identifying, classifying and analysing the diverse population of industry associations and the expressions of micro-politics that occur within them. Addressing key dilemmas such as leadership, resource allocation and regulation, Ronit examines the many policy areas in which industry associations are active and the areas in which their activities overlap with other policy actors. Offering a critical conceptual exploration of the significance of industry associations, this cutting-edge book is crucial reading for scholars and students researching business and politics, particularly those interested in associational governance in global industries. It will also benefit practitioners working in business associations and consulting firms, as well as policymakers addressing industry association
Optofluidics : process analytical technology
No full text"Optofluidics : Process Analytical Technology" offers in its 2nd edition a distinctive foundational introduction to the realms of materials, photonics, fluidics, and sensors. The work serves to unify the disparate disciplines, integrating the requisite fundamental knowledge with applied science. It thus establishes a new standard and definition for both the academic and industrial fields.
It encompasses the requisite in-depth knowledge of smart materials, semiconductor processing, optical waveguiding and fluid dynamics. The objective of this distinctive publication is to present information in a readily comprehensible format that can be readily applied in everyday situations. It is truly interdisciplinary but not overloading with information, providing the highly required and relevant information to become an expert in this exciting area, which is gaining more and more relevance and recognition in the context of sensing, material science and automation in biotechnology and pharmaceutical manufacturing.
The concept of the book is to serve as a textbook for advanced beginners from all life science, engineering and physics disciplines, providing self-assessment questions and further reading recommendations for further guidance and in-depth learning
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