96,536 research outputs found
Formal REA model at operational level
No full textDespite a lot of attention gained by the Resource-Event-Agent (REA) framework among researchers in enterprise modeling, it still lacks comprehensive formal description. Most of the formalization approaches to REA use only UML or other graphical representation. This paper aims to define REA ontology at operational level using formal logic tools. The general approach to formal logic description of REA was motivated by LTAP introduced by Ito, Hagihara and Yonezaki. After basic REA concepts are presented, semantics and logical language LREA are defined including axioms for the REA operational level. Future research is shortly described in conclusion.REA framework; formal models; modal logic
Enterprise modeling:process and REA value chain perspective
No full textThe paper focuses on enterprise business value chain modeling as an alternative to business process modeling. Well known REA methodology proposed by McCarthy and Geerts is used as the basic modeling framework. The research presented in the paper results in a generic semantic enterprise model using REA ontology. This rather static model is then converted into UML activity, sequence and state diagrams thus achieving dynamic view of the REA model. The dynamic REA view connects the process model and the value chain perspectives. It is shown that by using REA model transition called dynamization not only process models at task level can be achieved but also a consistency check of the REA model can be accomplished. By means of step by step value chain modeling of the enterprise a consistent process model can be reached preserving all advantages of the typical business process modeling methodsProcess model; Value chain model; REA; Production planning
Some Ontological Issues of the REA Framework in Relation to Enterprise Business Process
No full textThe aim of the paper is to describe using REA framework to model enterprise planning not only at the operational level but also at the policy level. Using policy level enlarges the possibility of the models on the base of the REA framework because the policy level in this way represents metalevel of the model. The policy level of the REA framework itself is comprised both of the entities related by typification, grouping and policy relationships and of the Commitment entity with the fulfillment relationship. This entity may be viewed as either a sublayer or a middle layer of the REA framework. The Commitment entity belongs to the fundamental entities of the policy level but has some specifications that are expressed by the fulfillment relationship. This many-to-many relationship forms the link to the operational level. In the paper we discuss the problem and suggest some solution that moves the Commitment entity closer to the typification and grouping semantic abstractions.REA ontology; enterprise business process; semantic abstractions
SOME ONTOLOGICAL ISSUES OF THE REA FRAMEWORK IN RELATION TO ENTERPRISE BUSINESS PROCESS
No full textThe aim of the paper is to describe using REA framework to model enterprise planning not only at the operational level but also at the policy level. Using policy level enlarges the possibility of the models on the base of the REA framework because the policy level in this way represents metalevel of the model. The policy level of the REA framework itself is comprised both of the entities related by typification, grouping and policy relationships and of the Commitment entity with the fulfilment relationship. This entity may be viewed as either a sub layer or a middle layer of the REA framework. The Commitment entity belongs to the fundamental entities of the policy level but has some specifications that are expressed by the fulfilment relationship. This many-to-many relationship forms the link to the operational level. In the paper we discuss the problem and suggest some solution that moves the Commitment entity closer to the typification and grouping semantic abstractions.REA ontology, enterprise business process, semantic abstractions
Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer
No full textBreast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells. Here we show a critical role of transactivation of BIG3, brefeldin A-inhibited guanine nucleotide-exchange protein 3, in activation of the estrogen/ER signaling in breast cancer cells. Knocking-down of BIG3 expression with small-interfering RNA (siRNA) drastically suppressed the growth of breast cancer cells. Subsequent co-immunoprecipitation and immunoblotting assays revealed an interaction of BIG3 with prohibitin 2/repressor of estrogen receptor activity (PHB2/REA). When BIG3 was absent, stimulation of estradiol caused the translocation of PHB2/REA to the nucleus, enhanced the interaction of PHB2/REA and ER[alpha], and resulted in suppression of the ER[alpha]; transcriptional activity. On the other hand, when BIG3 was present, BIG3 trapped PHB2/REA in cytoplasm and inhibited its nuclear translocation, and caused enhancement of ER[alpha]; transcriptional activity. Our results imply that BIG3 overexpression is one of the important mechanisms causing the activation of the estrogen/ER[alpha]; signaling pathway in the hormone-related growth of breast cancer cells
PSYNDEX Tests Review für REA-F - REAKTANZFRAGEBOGEN
No full textThis is a PSYNDEX Tests Review of REA-F - REAKTANZFRAGEBOGEN. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries. PSYNDEX Tests is offered by the Leibniz Institute for Psychology as open access documentation.Das ist ein PSYNDEX Tests Review zu REA-F - REAKTANZFRAGEBOGEN. PSYNDEX Tests Reviews beschreiben und bewerten zentrale psychologische und pädagogische Testverfahren, die in den deutschsprachigen Ländern eingesetzt werden, nach einem standardisierten Raster. PSYNDEX Tests wird durch das Leibniz-Institut für Psychologie als Open Access Dokumentation angeboten.publishedVersio
Gaze contingency in turn-taking for human robot interaction: Advantages and drawbacks
No full textPalinko O, Sciutti A, Schillingmann L, Rea F, Nagai Y, Sandini G. Gaze Contingency in Turn-Taking for Human Robot Interaction: Advantages and Drawbacks. Presented at the 24th IEEE International Symposium on Robot and Human Interactive Communication
Proportional Mens Rea
No full textThis Essay makes the case for proportional mens rea, a proportionality-based approach to mens rea selection. Proportional mens rea would provide proportionality safeguards that are otherwise entirely lacking in substantive criminal law and,as a practical matter, unavailable in constitutional law. Creating implied mens rea requirements, where necessary to ensure proportional punishment, is not a judicial usurpation of a legislative function. Rather, it is to take seriously the role that courts play, under both constitutional and substantive criminal law, to ensure that punishment fits the crime. Moreover, proportional mens rea would represent a needed counterweight to prosecutorial behavior whereas current doctrine does not. Given that federal prosecutors do not seek to charge morally blameless people, mens rea doctrine aimed only at protecting moral blamelessness from punishment will largely be redundant of prosecutorial discretion. Proportionality of punishment, however, is a concern that federal prosecutors—bound by long standing Executive Branch mandates to seek the maximum supportable penalty in every case and oppose lenient exercises of judicial sentencing discretion—routinely ignore. Judicial mens rea selection, therefore, has a substantial contribution to make to the achievement of proportionality of punishment
Lung transplantation for emphysema.
No full textEmphysema is a major cause of morbidity and mortality worldwide. Despite optimal medical therapy, smoking cessation, and pulmonary rehabilitation, a large number of patients remain symptomatic with a poor quality of life. A pool of patients with end-stage disease can benefit from surgical treatments like bullectomy, lung volume reduction, or lung transplantation. Emphysema represents the most common indication leading to lung transplantation. A functional improvement and better quality of life are clear benefits deriving from lung transplantation, while a survival advantage has not yet been proven
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