144 research outputs found
Participation is risky and clay analytics (book presentation and workshop;
No full textIn the Clay Analytics workshop you will use clay and light to approach the vocabulary that is touched upon in discourses around participation in art and design in a tangible way. The workshop was designed by Luna Maurer of Moniker in dialogue with Liesbeth Huybrechts, author of the book Participation is Risky. It uses clay and light play to make hands-on representations and even stories around words such as participation, user and maker, hybridity, autonomy, authorship, community and so on. Prior to the workshop Liesbeth gave a short introduction about the book
Participation is risky and clay analytics (book presentation and workshop;
No full textIn the Clay Analytics workshop you will use clay and light to approach the vocabulary that is touched upon in discourses around participation in art and design in a tangible way. The workshop was designed by Luna Maurer of Moniker in dialogue with Liesbeth Huybrechts, author of the book Participation is Risky. It uses clay and light play to make hands-on representations and even stories around words such as participation, user and maker, hybridity, autonomy, authorship, community and so on. Prior to the workshop Liesbeth gave a short introduction about the book
The use of photobiomodulation therapy for the prevention of chemotherapy-induced peripheral neuropathy: a randomized, placebo-controlled pilot trial (NEUROLASER trial)
No full textPurpose The purpose of this study was to investigate the effectiveness of photobiomodulation (PBM) therapy for the prevention of chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients. Methods A prospective, randomized placebo-controlled pilot trial (NEUROLASER) was set up with 32 breast cancer patients who underwent chemotherapy (ClinicalTrials.gov; NCT03391271). Patients were randomized to receive PBM (n = 16) or placebo treatments (n = 16) (2 × /week) during their chemotherapy. The modified Total Neuropathy Score (mTNS), six-minute walk test (6MWT), Numeric pain Rating Scale (NRS), and Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Taxane (FACT/GOG-Taxane) were used to evaluate the severity of CIPN and the patients' quality of life (QoL). Outcome measures were collected at the first chemotherapy session, 6 weeks after initiation of chemotherapy, at the final chemotherapy session, and 3 weeks after the end of chemotherapy (follow-up). Results The mTNS score increased significantly over time in both the control and the PBM group. A significantly higher score for FACT/GOG-Taxane was observed in the PBM group during chemotherapy compared to the control group. Questions of the FACT/GOG-Taxane related to sensory peripheral neuropathy symptoms showed a significant increase in severeness over time in the control group, whereas they remained constant in the PBM group. At follow-up, a (borderline) significant difference was observed between both groups for the 6MWT and patients' pain level, in benefit of the PBM group. Conclusions This NEUROLASER trial shows promising results concerning the prevention of CIPN with PBM in breast cancer patients. Furthermore, a better QoL was observed when treated with PBM.This research is funded by the Limburg Clinical Research Center (LCRC) UHasselt-ZOL-Jessa, Kom op tegen Kanker (Stand up to Cancer), the Flemish cancer society, the Limburgs Kankerfonds, and the Limburgse Kankersamenwerking
Looking back
No full textThese days the Government Architect is an influential consultant, who gets the attention of a number of government ministers. A Government Architect doesnt find much time to do any actual building though, and the same will be true for the new Government Architect, Liesbeth van der Pol, who was appointed in August. A look back at the old-fashioned Government Architects and their predecessors
Laaggeletterdheid te lijf met games. Deskundigen gaan de discussie aan
No full textKun je door het spelen van games laaggeletterdheid tegengaan onder jongeren? Deze vraag stond centraal in een onlangs gehouden debat hierover. Volgens Liesbeth Mantel, productonderzoeker bij TU Delft Library, is het te vroeg voor conclusies. Gedegen onderzoek heeft immers nog niet plaatsgevondenDelft University of Technolog
Steering self-organisation through confinement
No full textSelf-organisation is the spontaneous emergence of spatio-temporal structures and patterns from the interaction of smaller individual units. Examples are found across many scales in very different systems and scientific disciplines, from physics, materials science and robotics to biology, geophysics and astronomy. Recent research has highlighted how self-organisation can be both mediated and controlled by confinement. Confinement is an action over a system that limits its units’ translational and rotational degrees of freedom, thus also influencing the system's phase space probability density; it can function as either a catalyst or inhibitor of self-organisation. Confinement can then become a means to actively steer the emergence or suppression of collective phenomena in space and time. Here, to provide a common framework and perspective for future research, we examine the role of confinement in the self-organisation of soft-matter systems and identify overarching scientific challenges that need to be addressed to harness its full scientific and technological potential in soft matter and related fields. By drawing analogies with other disciplines, this framework will accelerate a common deeper understanding of self-organisation and trigger the development of innovative strategies to steer it using confinement, with impact on, e.g., the design of smarter materials, tissue engineering for biomedicine and in guiding active matter.</p
'Utrecht, Caravaggio and Europe', Centraal Museum Utrecht, 16 December 2018 - 24 March 2019. Catalogue: Eds. Bernd Ebert and Liesbeth M. Helmus, Munich, 2018, 304 pages, hardback, ISBN: 978-3-7774-3133-8, £45.00.
No full textUtrecht, Caravaggio and Europe brought together seventy paintings by the Utrecht Caravaggisti and their European counterparts to present the artistic vibrance that characterized Roman art between 1600 and 1630. What makes this exhibition stand out from the numerous ones that dealt with this artistic generation in the past – according to the author of this review - is its breaking free from the controversial definition of ‘Caravaggisti’ and from the long-standing notion of Caravaggio as the original. This review describes how the exhibition engages visitors in an independent work of observation that resembles what an early modern visitor would have experienced in a seventeenth-century gallery space. Attention is devoted to the way the thematic layout adopted visually highlights the pictorial differentiations that characterise, and therefore speak about, each artist’s pictorial paradigm. Particularly interesting to the author is the way the stylistic variety and pictorial identity that characterise each of the paintings on display also emerge through visual comparison with Caravaggio’s works, some of which take part to the exhibition but, remarkably, without becoming protagonists. By stimulating viewers to notice repetition but also discern differentiation and originality, curators Bernd Ebert and Liesbeth M. Helmus have proposed a new and more compelling way of revisiting what is now called Caravaggism
Knowing through dance-making: choreography, practical knowledge and practice as research (revised edition)
No full text© 2017, published by Routledge. The attached document (embargoed until 12/06/2019) is an author produced version of the chapter, uploaded in accordance with the publisher’s self- archiving policy
Knowing through dance-making: choreography, practical knowledge and practice as research (revised edition)
No full text© 2017, published by Routledge. The attached document (embargoed until 12/06/2019) is an author produced version of the chapter, uploaded in accordance with the publisher’s self- archiving policy
Evaluation of a zinc chelate on clinical swine dysentery under field conditions
No full textBackground Brachyspira hyodysenteriae is the primary cause of swine dysentery, characterized by bloody to mucoid diarrhea due to mucohaemorhagic colitis in pigs and primarily affects pigs during the grow/finishing stage. Control and prevention of B. hyodysenteriae consists of administration of antimicrobial drugs, besides management and adapted feeding strategies. A worldwide re-emergence of the disease has recently been reported with an increasing number of isolates demonstrating decreased susceptibility to several crucially important antimicrobials in the control of swine dysentery. A novel non-antibiotic zinc chelate has been reported to demonstrate positive effects on fecal quality and consistency, general clinical signs, average daily weight gain and B. hyodysenteriae excretion during and after a 6-day oral treatment. The objective of the present study was to evaluate the zinc chelate (Intra Dysovinol(R) 499 mg/ml (ID); Elanco) on naturally occurring swine dysentery due to B. hyodysenteriae under field conditions in the Netherlands. Results Oral administration of zinc chelate resulted in improvement of general clinical signs from 3 days onwards in the ID-treated group combined with a significantly better total fecal score at 14 days post-treatment. Overall, average daily weight gain was better in the ID-treated group over the entire study period (0-14 days) and during the 8 days following the end of ID-treatment. A significant reduction (4.48 vs. 0.63 log(10) cfu/g feces; ID-treated vs. control) in B. hyodysenteriae excretion was observed during the 6-day treatment period with a high percentage of animals (58.3 vs. 12.3%; ID-treated vs. control) with no excretion of B. hyodysenteriae from their feces. No additional antimicrobial treatment was needed in the ID-treated group, whereas 35% of the pigs in the control group were treated with an antibiotic at least once. No mortality occurred in both groups. No adverse events were reported during and following the ID-treatment. Conclusions Zinc chelate - administered as a Zn-Na-2-EDTA complex - is a non-antibiotic treatment for swine dysentery that reduces B. hyodysenteriae shedding with 4.48 log(10) cfu/g feces within its 6-day treatment while improving general clinical signs (90.0 vs. 73.6% animals with normal score) and total fecal score within 2-4 days following administration in naturally infected pigs. The positive effects of ID treatment remain for at least 8 days after cessation of oral ID therapy. Pigs remaining in a highly contaminated environment may be re-infected following the end of ID treatment, however, this is not different to standard antimicrobial therapy. Therefore, control of swine dysentery should combine an efficacious treatment with additional management practices to reduce the environmental infection pressure in order to limit re-infection as much as possible. The ID treatment resulted in a higher growth rate and improved general health, whereas no mortality was observed and no additional therapeutic treatments were necessary in contrast to the control pigs.The study was funded by Elanco Animal Health, which facilitated the conduct of the field trial.Vangroenweghe, F (reprint author), Elanco, BU Food Anim, Plantijn Moretuslei 1-3rd Floor, B-2018 Antwerp, Belgium.
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