70 research outputs found

    sj-docx-1-ine-10.1177_15910199241234098 - Supplemental material for Transvenous embolization of noncavernous dural arteriovenous fistulas (dAVFs): A systematic review and meta-analysis

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    Supplemental material, sj-docx-1-ine-10.1177_15910199241234098 for Transvenous embolization of noncavernous dural arteriovenous fistulas (dAVFs): A systematic review and meta-analysis by Jaims Lim, Brianna M. Donnelly, Vinay Jaikumar, Marissa D. Kruk, Cathleen C. Kuo, Andre Monteiro, Manhal Siddiqi, Ammad A. Baig, Devan Patel, Kunal P. Raygor, Kenneth V. Snyder, Jason M. Davies, Elad I. Levy and Adnan H. Siddiqui in Interventional Neuroradiology</p

    sj-docx-2-ine-10.1177_15910199241234098 - Supplemental material for Transvenous embolization of noncavernous dural arteriovenous fistulas (dAVFs): A systematic review and meta-analysis

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    Supplemental material, sj-docx-2-ine-10.1177_15910199241234098 for Transvenous embolization of noncavernous dural arteriovenous fistulas (dAVFs): A systematic review and meta-analysis by Jaims Lim, Brianna M. Donnelly, Vinay Jaikumar, Marissa D. Kruk, Cathleen C. Kuo, Andre Monteiro, Manhal Siddiqi, Ammad A. Baig, Devan Patel, Kunal P. Raygor, Kenneth V. Snyder, Jason M. Davies, Elad I. Levy and Adnan H. Siddiqui in Interventional Neuroradiology</p

    Watershed modeling using HEC-RAS, HEC-HMS, and GIS models: a case study of the Wreck Pond Brook Watershed in Monmouth County, New Jersey

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    Managing stormwater on a watershed basis is considered the best strategy to address flooding. A watershed model should provide temporal and spatial distribution of runoff response for a given storm. GIS applicability in watershed modeling is increasing due to the availability of spatial information, fast processors and interfaces such as ArcHydro, HEC-GeoHMS, and HEC-GeoRAS linking hydrologic and hydraulic models to the ArcGIS environment. Soil Conservation Service methods are used widely in hydrologic models. Several parameters inherent to these empirical methods are average values derived from various watershed conditions. These average values overestimate peak flows for flat, low-lying coastal terrains. The design of flood control structures based on these flow values allow more post-development discharge, make the system more hydraulically efficient, increase project costs, and cause flooding for areas downstream. In this study, Wreck Pond Brook Watershed (WPBW), a coastal New Jersey area was used for sensitivity studies of the initial abstraction ratio and peak rate factor. The HEC-HMS modeling results indicated use of a lower peak rate factor (e.g. 284) and 5% initial abstraction ratio provided better characterization of stream response. These updated parameters provide new technical information for improving stormwater management in coastal areas. An important limitation in hydraulic modeling is the economic constraint on cross-section spacing for surveying channels and floodplains. Applying GIS techniques in hydraulic modeling eliminated this constraint. Floodplain analysis was done using ArcGIS, HEC-GeoRAS and HEC-RAS. Detailed elevation data (LIDAR information from Monmouth County) was incorporated into the HEC-RAS using GIS models. This innovation was important for improving model efficiency. The modeled floodplain demonstrated close agreement to the observed floodplain for the October 2005 storm and showed greater accuracy compared to the FEMA floodplain for the 100-year storm. This study validated use of LIDAR elevation data in floodplain analysis for the second-order streams in coastal NJ. Finally, an approach was demonstrated using modeled floodplain and HEC-HMS for flood control analysis. This study presents an innovative watershed modeling approach using GIS models while addressing the limitations of traditional hydrologic and hydraulic methods using WPBW as an example.Ph.D.Includes bibliographical references (p. 259-263)by Kunal P. Pate

    Opportunities and challenges of investing in Indian real estate

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    Thesis (S.M.)--Massachusetts Institute of Technology, Program in Real Estate Development in Conjunction with the Center for Real Estate , 2009.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 125-128).In recent years, global real estate investment has become an important component of efficient global mixed asset portfolios. Although these investments carry increased political, regulatory and currency risk, international real estate investment has been on the rise. Compelling macroeconomic and demographic trends along with improvements in structural and regulatory conditions and investment in infrastructure are driving strong real estate capital flows into the emerging markets. This thesis provides a study of the opportunities and challenges of investing in one emerging market, India. With a population of over 1 billion, India has been a major beneficiary of the "Globalization of Real Estate". This thesis identifies the opportunities in India that have caused global capital to flow into Indian real estate and the key factors driving Indian real estate. It explains the challenges of investing in Indian real estate and seeks to provide strategies for navigating the real estate landscape in India.by Kunal Wadhwani.S.M

    Contralateral Anterior Interhemispheric Approach to Medial Frontal Arteriovenous Malformations: Surgical Technique and Results

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    BACKGROUND: Medial frontal arteriovenous malformations (AVMs) require opening the interhemispheric fissure and are traditionally accessed through an ipsilateral anterior interhemispheric approach (IAIA). The contralateral anterior interhemispheric approach (CAIA) flips the positioning with themidline still positioned horizontally for gravity retraction, but with the AVM on the upside and the approach from the contralateral, dependent side. OBJECTIVE: To determine whether the perpendicular angle of attack associated with the IAIA converts to a more favorable parallel angle of attack with the CAIA. METHODS: The CAIA was used in 6 patients with medial frontal AVMs. Patients and AVM characteristics, as well as pre- and postoperative clinical and radiographic data, were reviewed retrospectively. RESULTS: Four patients presented with unruptured AVMs, with 5 AVMs in the dominant, left hemisphere. The lateral margin was off-midline in all cases, and average nidus size was 2.3 cm. All AVMs were resected completely, as confirmed by postoperative catheter angiography. All patients had good neurological outcomes,with either stable or improved modified Rankin Scores at last follow-up. CONCLUSIONS: This study demonstrates that the CAIA is a safe alternative to the IAIA for medial frontal AVMs that extend 2 cm or more off-midline into the deep frontal white matter. The CAIA aligns the axis of the AVMnidus parallel to the exposure trajectory, brings its margins in view for circumferential dissection, allows gravity to deliver the nidus into the interhemispheric fissure, and facilitates exposure of the lateral margin for the final dissection, all without resecting or retracting adjacent normal cortex

    K*(892)± resonance with the ALICE detector at LHC

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    K*(892)± resonance with the ALICE detector at LHC Author: Kunal Garg PhD Cycle XXXI, University of Catania It has been established that ultra-relativistic heavy-ion collisions produce a hot and dense QCD system which behaves like a perfect fluid. The study of the Quark Gluon Plasma created in these collisions is important to understand the cosmic evolution of our Universe. The study of strange hadronic resonances in pp collisions contributes to the study of strangeness production in small systems. Usually, measurements in pp collisions constitute a reference for the study in larger colliding systems and provide constraints for tuning QCD-inspired event generators and then to test specific aspects of QCD in the non-perturbative sector. However recent observations at the LHC have shown striking similarities between Pb-Pb collisions and high-multiplicity p-Pb and pp collisions. In the elementary collisions a large variation of the characteristics of the event and of the strange particle production rate has been observed as a function of the charged particle multiplicity density. In particular it has been observed as particle production depends only from the event multiplicity and it is independent of the system size and collision energy. This thesis reports about first measurement of K^{*}(892)^{\pm} in pp collisions at \sqrt{s} = 13 TeV in inelastic pp collisions and in different charged particle multiplicity classes. In particular the transverse momentum (p_{T}) spectrum, the integrated yield, the mean p_{T} and the ratio to stable hadrons as pions and kaons have been measured. Moreover the K^{*}(892)^{0} p_{T} spectrum in inelastic pp collisions at the same energy has been also measured. Similar results have been obtained for charged and neutral K^{*}. The K*(892)± p_{T} spectrum has been compared to the predictions of some event generators as PYTHIA6, PYTHIA8 and EPOS-LHC. Furthermore, the comparison of the p_{T} spectrum with the one obtained at different energies has shown a hardening of the spectra with increasing energy of the collisions. Increase of the K*(892)± yield and mean p_{T} when growing the event multiplicity, confirms the independence of the particle yields from the collision system or energy. From the distribution of the K^{*}/K ratio as a function of the charged particle multiplicity, a hint of suppression of the K* production has been observed in high multiplicity pp collisions. This in an analogy to the K^{*}/K results in heavy-ion collisions, is consistent with the presence of re-scattering effects in an hadronic phase in high multiplicity pp collisions

    The thermal response of biological tissue subjected to short-pulsed irradiations:

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    A combined transient radiation and hyperbolic heat conduction model is developed to simulate heat transfer of biological tissue subjected to short pulsed irradiations. For modeling the ultrafast radiation heat transfer, the Transient Discrete Ordinate Method (TDOM) is developed in the two-dimensional axisymmetric cylindrical coordinates. The hyperbolic conduction model is solved by MacCormack’s scheme with error terms correction. One combination model of radiation and heat conduction is that the radiation transfer is initiated by short pulse train irradiating until millisecond time scale and heat conduction transfer is followed. The temperature always increases by the radiation transfer and the heat is dissipated to the surrounding tissue by the hyperbolic heat conduction. The typical characteristic of the hyperbolic conduction is the thermal wave propagation rather than thermal diffusion with indefinite speed. It is found that the maximum local temperatures are higher in the hyperbolic prediction than the parabolic prediction, which can be 7% higher in the modeled dermis tissue. After about 10 thermal relaxation times, thermal waves fade away and the predictions between the hyperbolic and parabolic models are closely consistent. Other combination model is that radiation and conduction transfer always occurs together until a second time regime. The temperature prediction is compared with the experimental result provided by Dr. Kunal Mitra’s group. Generally, the hyperbolic model combined with radiative heat transfer shows very similar result with the experimental data. It also shows high temperature increment near the laser deposition area compared with the parabolic model. Own experimental study is conducted to evaluate the hyperbolic heat conduction phenomena. The fresh chicken tissue which is conserved the room temperature is suddenly contacted the ice block. Some of the results support the hyperbolic model by the temperature suddenly dropping rather that gradual temperature change. The high absorbing tissue can enhance the radiation energy absorption and temperature increment is higher. The temperature increment is localized in the tissue surface region in the high scattering tissue. The focused laser beam played a role of temperature amplification around the focal region. The finer grid system is employed to catch up steep change of gradient of radiation energy absorption.Ph.D.Includes bibliographical references (p. 184-190)by Kyunghan Ki

    Socioeconomic factors associated with pediatric moyamoya disease hospitalizations: a nationwide cross-sectional study

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    ObjectiveHealthcare disparities are widely described in adults, but barriers affecting access to care for pediatric patients with moyamoya disease (MMD) are unknown. Understanding socioeconomic factors impacting hospital access and outcomes is necessary to address pediatric healthcare disparities.MethodsIn this cross-sectional observational study, the Kids' Inpatient Database was used to identify patients admitted with a primary diagnosis of MMD from 2003 to 2016. Patients ≤ 18 years with a primary diagnosis of MMD based on International Classification of Diseases (ICD) codes were included. Hospital admissions were queried for use of cerebral revascularization based on ICD procedure codes.ResultsQuery of the KID yielded 1449 MMD hospitalizations. After multivariable regression, Hispanic ethnicity (OR 0.52 [95% CI 0.33-0.81], p = 0.004) was associated with lack of surgical revascularization. Private insurance (OR 1.56 [95% CI 1.15-2.13], p = 0.004), admissions at medium- and high-volume centers (OR 2.01 [95% CI 1.42-2.83], p &lt; 0.001 and OR 2.84 [95% CI 1.95-4.14], p &lt; 0.001, respectively), and elective hospitalization (OR 3.37 [95% CI 2.46-4.64], p &lt; 0.001) were positively associated with revascularization. Compared with Caucasian race, Hispanic ethnicity was associated with increased mean (± SEM) length of stay by 2.01 ± 0.70 days (p = 0.004) and increased hospital charges by 24,333.61±24,333.61 ± 7918.20 (p = 0.002), despite the decreased utilization of surgical revascularization. Private insurance was associated with elective admission (OR 1.50 [95% CI 1.10-2.05], p = 0.01) and admission to high-volume centers (OR 1.90 [95% CI 1.26-2.88], p = 0.002). African American race was associated with the development of in-hospital complications (OR 2.52 [95% CI 1.38-4.59], p = 0.003).ConclusionsAmong pediatric MMD hospitalizations, multiple socioeconomic factors were associated with access to care, whether surgical treatment is provided, and whether in-hospital complications occur. These results suggest that socioeconomic factors are important drivers of healthcare disparities in children with MMD and warrant further study
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