102 research outputs found
Endoscopic evaluation of upper and lower gastro-intestinal bleeding
No full textIntroduction: A myriad of pathologies lead to gastro-intestinal bleeding (GIB). The common clinical presentations are hematemesis, melena, and hematochezia. Endoscopy aids localization and treatment of these lesions. Aims: The aim was to study the differential diagnosis of GIB emphasizing the role of endoscopy in diagnosis and treatment of GIB. Patients and Methods: A prospective study of patients with GIB referred to the Endoscopy unit of two health facilities in Port Harcourt Nigeria from February 2012 to August 2014. The variables studied included: Demographics, clinical presentation, risk score, endoscopic findings, therapeutic procedure, and outcome. Data were collated and analyzed using SPSS version 20 software. Results: A total of 159 upper and lower gastro-intestinal (GI) endoscopies were performed during the study period with 59 cases of GI bleeding. There were 50 males and 9 females with an age range of 13-86 years (mean age 52.4 20.6 years). The primary presentations were hematochezia, hematemesis, and melena in 44 (75%), 9 (15%), and 6 (10%) cases, respectively. Hemorrhoids were the leading cause of lower GIB seen in 15 cases (41%). The majority of pathologies in upper GIB were seen in the stomach (39%): Gastritis and benign gastric ulcer. Injection sclerotherapy was successfully performed in the hemorrhoids and a case of gastric varices. The mortality recorded was 0%. Conclusion: Endoscopy is vital in the diagnosis and treatment of GIB. Gastritis and Haemorrhoid are the most common causes of upper and lower GI bleeding respectively, in our environmen
Epidemiology of Gastrointestinal Malignancies in Nigeria:Port Harcourt Cancer Registry Study
No full textThe Future of Inclusive Green Growth and Creation of Decent Jobs in Developing Countries: Attracting Investments for Inclusive Green Growth and Creation of Decent Jobs
No full textA Critical Review of Distress Syndrome in Nigerian Banks with a View to Preventing Recurrence
No full textUpper Gastro-Intestinal Endoscopy in Port Harcourt, Nigeria: An Audit
No full textBackground: Accurate diagnosis of disease conditions using laboratory, imaging or endoscopic investigation is essential for appropriate treatment. There is paucity of data on upper GI endoscopy in Port-Harcourt. This audit of our early experience is intended to provide data on the pattern of endoscopy findings which is needed to improve the quality of patient care. The study aims to report the pattern of presentation as well as the endoscopic and pathologic findings of symptomatic upper gastro-intestinal disease conditions.Method: All consecutive patients presenting to the endoscopy unit of a private hospital from February 2012to October 2018 were prospectively studied. The sociodemographics, indications, endoscopic findings and histopathologic report for biopsies were collated. Data was statistical analyzed using SPSS version20.Results: There were 44 OGDsin 87 patients performed during the study period. Twenty-one were males and 16 females. A male: female ratio of 1.8:1 and age range from 5-86years(mean 46.4±18.5 years).The major indications were dyspepsia 28(52.8%) and dysphagia 8(18%).Nonulcerative gastritis was the most common endoscopic finding seen in 16 (82%) cases and more than one pathologic condition was seen in 8(18%)cases.Conclusion: Peptic ulcer is not the most common cause of dyspepsia. Gastritis and multiple nonulcer pathologies in a patient are more common thus the need for thorough endoscopic investigation in symptomatic upper GI disease.Keywords: Upper gastro-intestinal tract, endoscopy, audi
Screening colonoscopy in Port Harcourt, Nigeria
No full textColonoscopy is a screening tool for colorectal cancer. The cost of this service, ready availability and expertise are factors limiting its routine use in low-/middle-income countries. The aim was to study premalignant colonic polyps in asymptomatic middle-aged Nigerians and highlight the usefulness of screening colonoscopy in a sub-Saharan African population. We carried out an observational study on asymptomatic patients undergoing screening colonoscopy in a referral endoscopy facility in Port Harcourt, Rivers State, Nigeria from January to December 2018. The variables collated were demographics, endoscopic and histologic findings. Statistical analysis was done using IBM SPSS Statistics for Windows, version 20 Armonk, NY. A total of 144 colonoscopy procedures were performed during the study period with 70 asymptomatic cases for screening indication. Sixty-five were males and 5 females. The age range was from 48 years to 60 years; mean 54.8 ± 3.6 years. A polyp-detection rate of 53.7% was recorded with multiple polyps seen in 13 cases. Adenoma(s) detected in 19 persons were: 22 tubular adenomas with low grade dysplasia; 3 tubulo-villous adenomas with low grade dysplasia; 1 sessile serrated adenoma. The adenoma detection rate was 28.8%. No abnormality was detected in 19 cases. There is a worrisome prevalence of adenomatous polyps; villous adenoma is rare. A targeted policy of screening and surveillance by colonoscopy will curb the rising incidence of colorectal cancer
A Critical Evaluation of the Role of the Central Bank of Nigeria in Ensuring Corporate Governance in Nigerian Banks Post Consolidation
No full textThe Effects of Different Infestation Levels of Callosobruchus Maculatus F. on Stored Cowpea (Vigna Unguiculata Walp)
No full textSodium picosulfate/magnesium citrate versus 4L split-dose polyethylene glycol for bowel cleansing prior to colonoscopy in high fibre diet African patients
No full textIntroduction: an adequate bowel preparation is essential for good mucosal inspection during colonoscopy. This study aims to compare the efficacy of two validated oral lavage solutions for colonoscopy preparation in African patients.
Methods: a prospective observational study of patients undergoing colonoscopy in a referral endoscopy facility in Port Harcourt, Nigeria, using sodium picosulfate magnesium citrate (SPMC) and 4L split-dose polyethylene glycol (PEG). Variables collated were sociodemographic, primary indication, comorbidities, Aronchick bowel preparation scale, polyp/adenoma detection, caecal intubation and outcome. Statistical analysis was performed using IBM SPSS version 20.
Results: one hundred and twenty-four patients received PEG prior to colonoscopy and SPMC in 175 patients. The age range was from 22 to 92 years; mean age of 53.8 ± 14.2 years for PEG group and 55.3 ± 13.2 years for SPMC group (p=0.361). There were 215 males and 84 females. An excellent/good bowel preparation scale was recorded in 77 (62%) PEG group and 130 (74.3%) for SPMC group (p=0.592). PEG was predominantly used in the early years of endoscopists practice with the odds ratio (OR) of no polyp detection in the PEG vs SPMC groups as 1.64 (confidence interval CI 1.06-2.55) versus 0.76 (CI 0.62-0.92), respectively (p=0.016). For no adenoma detection, OR was 4.18 (CI 1.12-15.60) versus OR 0.63 (CI 0.52-0.75), respectively (p=0.012).
Conclusion: there is similar efficacy profile using either split volume PEG or SPMC prior to colonoscopy in these African patients. Polyp and adenoma detection rates are highly dependent on the expertise of the endoscopist
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