300 research outputs found
Retinal and optic nerve changes in microcephaly: an optical coherence tomography study
No full textObjective To investigate the morphology of the retina and optic nerve (ON) in microcephaly.Methods This was a prospective case-control study including 27 patients with microcephaly and 27 healthy controls. All participants underwent ophthalmologic examination and handheld optical coherence tomography (OCT) of the macula and ON head. The thickness of individual retinal layers was quantified at the foveal center and the parafovea (1,000 μm nasal and temporal to the fovea). For the ON head, disc diameter, cup diameter, cup-to-disc ratio, cup depth, horizontal rim diameter, rim area, peripapillary retinal thickness, and retinal nerve fiber layer thickness were measured.Results Seventy-eight percent of patients had ophthalmologic abnormalities, mainly nystagmus (56%) and strabismus (52%). OCT abnormalities were found in 85% of patients. OCT revealed disruption of the ellipsoid zone, persistent inner retinal layers, and irregular foveal pits. Parafoveal retinal thickness was significantly reduced in patients with microcephaly compared to controls, nasally (307 ± 44 vs 342 ± 19 μm, p = 0.001) and temporally (279 ± 56 vs 325 ± 16 μm, p < 0.001). There was thinning of the ganglion cell layer and the inner segments of the photoreceptors in microcephaly. Total peripapillary retinal thickness was smaller in patients with microcephaly compared to controls for both temporal (275 vs 318 μm, p < 0.001) and nasal sides (239 vs 268 μm, p = 0.013).Conclusions Retinal and ON anomalies in microcephaly likely reflect retinal cell reduction and lamination alteration due to impaired neurogenic mitosis. OCT allows diagnosis and quantification of retinal and ON changes in microcephaly even if they are not detected on ophthalmoscopy
Films in the diplomatic bag:Sovereignty, censorship and the foreign mission film in East Pakistan & Bangladesh
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Bibliotheca: The Road to Wisdom
No full textThere is a path which takes any creative intellect from the world of information to that of wisdom through the world of knowledge. This path for creative realization is indeed resonant with the \u27Upanishadic\u27 method of spiritual realization, i.e. the transformative ideology of the East, consisting of the phases of \u27Sravana\u27, \u27Manana\u27, and \u27Nididhyasana\u27 in that order, with the outcome of the phases being Information, Knowledge and Wisdom respectively. This has been seen to be true in the case of legendary literary work and unparalleled epic of the East, \u27Mahabharata\u27, inspired the master writer of India, MT Vasudevan Nair in penning an equally legendary work \u27Randamoozham\u27 (Second Turn), in this comparatively limited linguistic realm and the role played by libraries in that creative endeavor. The literary creative route of \u27Randamoozham\u27 the author vindicating the hypothesis; \u27Library is the right fulgent path for transforming information through knowledge to wisdom.\u2
ICAS:MP Special Lecture by Raka Ray (University of California, Berkeley)
No full textPicture: Wikimedia Commons Resentment and Revenge: Internal Colonialism, the Decline of Fordism and the Trump Vote Chair and Discussant: Ravi Vasudevan (Centre for the Study of Developing Societies, Delhi) 2 December 2019 Venue: CSDS, Seminar Room, 4:30 pm – 7 pm Abstract: The question of why the working class, and the white working class in particular voted for Trump has obsessed liberals in the US. The Washington Post asks, “Why are so many white men so angry?” How do we understand the lur..
[CLOSED] Call for Researchers for Thematic Module 7: Media and the Constitution of the Political (TM7)
No full textICAS: MP, TM7, invites applications for junior researcher positions. These are for archival collections, ethnographic research and interviews, and legal research, under the supervision of module coordinators Ravi Vasudevan (CSDS) and Srirupa Roy (University of Goettingen). The thematic focuses of the research include: Social Media, Data and Information infrastructures This project looks at data and information infrastructures that have emerged from the rise of social media. The expansion of s..
Spectropolarimetry of life: Airborne measurements from a hot air balloon
No full textDoes life exist outside our Solar System A first step towards searching for life outside our Solar System is detecting life on Earth by using remote sensing applications. One powerful and unambiguous biosignature is the circular polarization resulting from the homochirality of biotic molecules and systems. We aim to investigate the possibility of identifying and characterizing life on Earth by using airborne spectropolarimetric observations from a hot air balloon during our field campaign in Switzerland, May 2022. In this proceeding we present the optical-setup and the data obtained from aerial circular spectropolarimetric measurements of farmland, forests, lakes and urban sites. We make use of the well-calibrated FlyPol instrument that measures the fractionally induced circular polarization (V/I) of (reflected) light with a sensitivity of < 10-4. The instrument operates in the visible spectrum, ranging from 400 to 900 nm. We demonstrate the possibility to distinguish biotic from abiotic features using circular polarization spectra and additional broadband linear polarization information. We review the performance of our optical-setup and discuss potential improvements. This sets the requirements on how to perform future airborne spectropolarimetric measurements of the Earth's surface features from several elevations. Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Astrodynamics & Space Mission
Intraoral plasmablastic non-hodgkin's lymphoma associated with human immunodeficiency virus
No full textPlasmablastic Lymphoma of oral cavity is an aggressive rare form of Non Hodgkin's Lymphoma which is an Acquired Immuno Deficiency Syndrome defining condition. Head and neck region is the second most common area for extranodal NHL's primarily involving gingiva and palate, which often presents as a diagnostic problem. We report a case of PBL in a 19 year old female patient later diagnosed as Human Immunodeficiency Virus (HIV) positive. She presented with expanding painful ulceroproliferative lesion involving left mandible and gingiva of 20 days duration. Histopathological examination and immunohistochemical analysis confirmed the diagnosis. Uncommon discovery of multiple bony lesions in whole body CT and hypercalcemia raise a question about Multiple Myeloma (MM). Literature showed very few cases with osteolytic lesions and none of the cases reported multiple bone lesions in skull. Our case report stresses the importance of differentiating this extremely rare case of PBL with skull lesions from MM
Analyzing Support for U.S. Presidential Candidates in Twitter Polls
No full textPolls posted on social media can provide information about public opinion on a variety of issues from business decisions to support for presidential election candidates. However, it is largely unknown whether the information provided by social polls is useful or not. To enhance our understanding of social polls, we examine nearly two thousand Twitter polls gauging support for U.S. presidential candidates during the 2016 and 2020 election campaigns.
First, we describe the prevalence of social polls. Second, we characterize social polls in terms of the engagement they elicit and the response options they present. Third, leveraging machine learning models, we infer and describe several characteristics, including demographics and political leanings, of the users who author and interact with social polls. Finally, we study the relationship between social poll results, their attributes, and the characteristics of users interacting with them. Our findings suggest how and to what extent polling on Twitter is biased in terms of content, authorship, and audience. The 2016 and 2020 polls were predominantly crafted by older males and manifested a pronounced bias favoring candidate Donald Trump, whereas traditional surveys favored Democratic candidates. We further identify and explore the potential reasons for such biases and discuss their repercussions
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