4,492 research outputs found
Sclerosis multiplex’i tänapäevane ravi
No full textSclerosis multiplex (SM) on kõige sagedasem noortel täiskasvanutel puuet põhjustav neuroloogiline haigus. Haiguskulu järgi eristatakse ägenemiste ja remissioonidega, ägenemistega sekundaarse progresseerumisega, ägenemisteta sekundaarse progresseerumisega ja primaarse progresseerumisega SMi vormi. SMi puhul on kasutusel
ägenemiste, haiguse kulgu mõjutav ja sümptomaatiline ravi. Ägenemiste raviks kasutatakse metüülprednisolooni. Haiguse kulgu mõjutavad ravimid on profülaktilised, vähendavad ägenemiste arvu ning on efektiivsed ainult ägenemistega haiguskulu korral. Ravimitest on esmavalikuna kasutusel süstitavad beetainterferoonid ja glatirameeratsetaat. Esmavaliku preparaatide ebapiisava efektiivsuse või väga agressiivse kuluga haiguse puhul on näidustatud ka tsütostaatiline ravi
mitoksantrooni või tsüklofosfamiidiga. Varajane ravi on tõhusam kui hiline. Käigusolevad ravimiuuringud annavad lootust, et tulevikus võetakse kasutusele ka suu kaudu manustatavad preparaadid.
Eesti Arst 2009; 88(2):117−12
Yeast metabolism in fresh and frozen dough : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology at Massey University, Palmerston North, New Zealand
No full textAuthor also known as SM LovedayFresh bakery products have a very short shelf life, which limits the extent to which manufacturing can be centralised. Frozen doughs are relatively stable and can be manufactured in large volumes, distributed and baked on-demand at the point of sale or consumption. With appropriate formulation and processing a shelf life of several months can be achieved.Shelf life is limited by a decline in proofing rate after thawing, which is attributed to a) the dough losing its ability to retain gas and b) insufficient gas production, i.e. yeast activity. The loss of shelf life is accelerated by delays between mixing and freezing, which allow yeast cells the chance to ferment carbohydrates.This work examined the reasons for insufficient gas production after thawing frozen dough and the effect of pre-freezing fermentation on shelf life. Literature data on yeast metabolite dynamics in fermenting dough were incomplete. In particular there were few data on the accumulation of ethanol, a major fermentation end product which can be injurious to yeast.Doughs were prepared in a domestic breadmaker using compressed yeast from a local manufacturer and analysed for glucose, fructose, sucrose, maltose and ethanol. Gas production after thawing declined within 48 hours of frozen storage. This was accelerated by 30 or 90 minutes of fermentation at 30;C prior to freezing.Sucrose was rapidly hydrolysed and yeast consumed glucose in preference to fructose. Maltose was not consumed while other sugars remained. Ethanol, accumulated from consumption of glucose and fructose, was produced in approximately equal amounts to CO2, indicating that yeast cells metabolised reductively.Glucose uptake in fermenting dough followed simple hyperbolic kinetics and fructose uptake was competitively inhibited by glucose. Mathematical modelling indicated that diffusion of sugars and ethanol in dough occurred quickly enough to eliminate solute gradients brought about by yeast metabolism
Portable smart messages architecture for ubiquitous Java-enabled devices
No full textThis paper presents the design and implementation of a lightweight and flexible middleware, based on Smart Messages (SMs), for programming distributed applications over networks of ubiquitous Java-enabled devices, such as cell phones and PDAs. SMs are user-defined distributed applications which execute on nodes of interest, named by their properties, and use explicit migration to move between these nodes. The main benefits provided by SMs are ease of deployment for new applications and adaptability to highly dynamic network conditions. To leverage the computing power of existent wireless Java-enabled devices, we have designed a portable SM architecture in which the SM support at nodes is implemented as a runtime system on top of pre-installed Java virtual machines, and the SM migration is implemented by instrumenting the SM Java bytecode. The experimental results for applications executed over a testbed consisting of HP iPAQs communicating through 802.11 wireless cards demonstrate the feasibility of our architecture.Technical report DCS-TR-53
Converting SrI <sub>2</sub> :Eu <sup>2+</sup> into a near infrared scintillator by Sm <sup>2+</sup> co-doping
No full text The luminescence and scintillation properties of SrI 2 single crystals doped with 5% Eu 2+ and 0.05%, 0.2% and 0.5% Sm 2+ are evaluated. X-ray excited and photoluminescence measurements show energy transfer from excited Eu 2+ ions to Sm 2+ ions. At a concentration of 0.5% Sm 2+ , the luminescence consists almost entirely of 740 nm emission from Sm 2+ 5d-4f transitions. Co-doping SrI 2 :5% Eu 2+ with Sm 2+ provides a novel method to bypass the self-absorption problem encountered in large SrI 2 :Eu 2+ crystals and, at the same time, provides a unique near-infrared emitting scintillator with a light yield of approximately 40,000 photons/MeV. Accepted Author ManuscriptRST/Fundamental Aspects of Materials and EnergyRST/Luminescence Material
'Laws 'Needefull in Later to be Abrogated': Intersex and the Sources of Christian Theology
No full textThis is the author accepted manuscript. The final version is available from Palgrave Macmillan via the DOI in this record
Introduction: Troubling Bodies?
No full textThis is the author accepted manuscript. The final version is available from Palgrave Macmillan via the DOI in this record
Intrafullerene electron transfers in Sm-containing metallofullerenes: Sm@C-2n (74 <= 2n <= 84)
No full textThe electronic properties of Sm-containing metallofullerenes, Sm@C-74, Sm@C-76 (I, II), Sm@C-78, Sm@C-80, Sm@C-82 (I, II, III) and Sm@C-84 (I, II, III), are characterized by UV-Vis-NIR absorption spectroscopy and electron energy-loss spectroscopy (EELS). the UV-Vis-NIR absorption spectra of Sm@C-74, Sm@C-80, Sm@C-82 (I, II, III) and Sm@C-84 (I, II) are quite similar to those of the corresponding Ca, Sr, Ba, Eu, Tm, Yb-based metallofullerenes. In contrast, the absorption spectra of Sm@C-76 (I, II), Sm@C-78 and Sm@C-84(III) show a novel feature: the onset for Sm@C-78 is observed similar to 2600 nm, which corresponds to a small band gap (similar to0.5 eV). Furthermore, the oxidation states of Sm atom in the various fullerene cages are investigated by EELS, which reveals that the Sm atom takes +2 oxidation state in the fullerene cages. A probable rationale for the tendency to have the Sm2+ state is presented based on a simple thermochemical cycle model. (C) 2001 by Elsevier Science Inc.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000168906500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Biochemical Research MethodsBiochemistry & Molecular BiologyComputer Science, Interdisciplinary ApplicationsCrystallographyMathematical & Computational BiologySCI(E)EI30ARTICLE2244-2511
beta-decay spectroscopy of neutron-rich Sm-160,Sm-161,Sm-162 isotopes
No full textNeutron-rich Sm-160,Sm-161,Sm-162 isotopes have been populated at the RIBF, RIKEN via beta decay for the first time. beta-coincident gamma rays were observed in all three isotopes including gamma rays from the isomeric decay of Sm-160 and Sm-162. The isomers in Sm-160 and Sm-162 have previously been observed but have been populated via beta decay for the first time. The isomeric state in Sm-162 is assigned a 4(-) nu 7/2(+)[633]circle times nu 1/2(-)[521] configuration based on the decay pattern. The level schemes of Sm-160 and Sm-162 are presented. The ground states in the parent nuclei Pm-160 and Pm-162 are both assigned a 6(-) nu 7/2(+)[633]circle times pi 5/2(-)[532] configuration based on the population of states in the daughter nuclei. Blocked BCS calculations were performed to further investigate the spin-parities of the ground states in Pm-160, Pm-161, and Pm-162, and the isomeric state in Sm-162.CPCI-S(ISTP)[email protected]
Discovering the Similarities between SM Communities and Other Organizations
No full textThe current research study is comparing and contrasting the demographic diversity of Sadomasochist (SM) organizations and other community organizations by surveying an SM organization and a non-SM organization. A confidential online survey was used to collect data. Fourteen general questions were asked: age, gender, sexual orientation, relationship status, number of children, ethnicity, highest level of education completed, employment, hours worked, income, religious affiliation, personality, infidelity and self esteem. Data was analyzed using Levene\u27s test and t-tests. Relationship status and religion were two differences between the SM group and the non SM group. The author discusses limitations and future directions of this study
Next Generation of 100-μm-Pitch Wafer-Level Packaging and Assembly for Systems-on-Package
No full textAccording to the latest ITRS roadmap, the pitch of area array packages is expected to decrease to 100 µm by 2009. Simultaneously, the electrical performance of these interconnections needs to be improved to support data rates in excess of 10 Gbps, while guaranteeing thermomechanical reliability and lowering the cost. These requirements are challenging, thus, needing innovative interconnection designs and technologies. This paper describes the development of three interconnection schemes for wafer-level packages (WLPs) at 100-µm-pitch, involving rigid, compliant, and semicompliant interconnection technologies, extending the state of the art in each. Extensive electrical and mechanical modeling was carried out to optimize the geometry of the interconnections with respect to electrical performance and thermomechanical reliability. It was found that the requirements of electrical performance often conflict with those of thermomechanical reliability and the final “optimum” design is a tradeoff between the two. For the three interconnection schemes proposed, it was found that the electrical requirements can be met fairly well but acceptable mechanical reliability may require organic boards with coefficient of thermal expansion of 10 ppm/K or lower
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