143 research outputs found
Clinical and histological healing of a new collagen matrix in combination with the coronally advanced flap for the treatment of Miller class-I recession defects: an experimental study in the minipig
No full textAim: To describe the histological and clinical outcomes of the use of a xenogeneic collagen matrix (CM) in combination with the coronally advanced flap (CAF) in the treatment of localized Miller class-I gingival recessions.Material and Methods: Gingival recession defects were surgically created on 12 minipigs. The defects were randomly treated with either the CAF procedure and the interposition of a CM (test) or the CAF alone (control). Clinical and histological outcomes at 1, 4 and 12 weeks were evaluated.Results: Histometrically, in the test group, there was a shorter junctional epithelial dimension [2.26 (SD 0.23) mm] compared with the control [2.79 (SD 0.77) mm]. On the contrary, the amount of newly formed cementum was larger in the test group [1.08 (SD 0.41) mm] than in the control group [0.75 (SD 0.25) mm], although the differences were not statistically significant.Conclusions: Both techniques rendered similar clinical outcomes, achieving complete root coverage at the end of the study. Nevertheless, the CM graft attained more tissue regeneration, characterized by a shorter epithelium and a larger new cementum formation. The use of a xenogeneic CM resulted in the incorporation of the xenograft within the adjacent host connective tissues in the absence of significant inflammation
Removal of Amalgam Overhangs: A Profilometric and Scanning Electron Microscopic Evaluation
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142188/1/jper0245.pd
Treatment of Localized Gingival Recessions: Part III. Comparison of Results Obtained With Lateral Sliding and Coronally Repositioned Flaps
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141093/1/jper0457.pd
Treatment of Localized Gingival Recessions: Part I. Lateral Sliding Flap
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141540/1/jper0351.pd
Treatment of Localized Gingival Recessions: Part II. Coronally Repositioned Flap with a Free Gingival Graft
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142129/1/jper0357.pd
Effect of mechanical and antiseptic therapy on peri-implant mucositis: an experimental study in monkeys
No full textOBJECTIVES: This experiment was performed to evaluate clinically and histologically the effect of mechanical therapy with or without antiseptic therapy on peri-implant mucositis lesions in nine cynomolgus monkeys. MATERIAL AND METHODS: Two ITI titanium implants were inserted into each side of the mandibles. After 90 days of plaque control and soft tissue healing, a baseline clinical examination was completed. Peri-implant lesions were induced by placing silk ligatures and allowing plaque to accumulate for 6 weeks. The clinical examination was then repeated, and the monkeys were randomly assigned to three treatment groups: group A, mechanical cleansing only; group B, mechanical cleansing and local irrigation with 0.12% chlorhexidine (CHX) and application of 0.2% CHX gel; and group C, control, no treatment. The implants in treatment groups A and B were treated and maintained according to the assigned treatment for two additional months. At the end of the maintenance period, a final clinical examination was performed and the animals were sacrificed for biopsies. RESULTS: The mean probing depths (PD) values at mucositis were: 3.5, 3.7, and 3.4 mm, and clinical attachment level (CAL) = 3.8, 4.1, and 3.9 mm for treatment groups A, B and C, respectively. The corresponding values after treatment were: PD = 1.7, 2.1, and 2.5 mm, and CAL=2.6, 2.6, and 3.1 mm. ANOVA of mean changes (Delta) in PD and CAL after treatment showed no statistical difference between the treatment groups. Comparison of the mean changes in PD and CAL after treatment yielded statistical differences between the control and treatment groups P < 0.01. According to the t-test, no statistical difference was found between treatment groups A and B for the PD reduction but there was a significant difference for the CAL change, P < 0.03. Group A had significantly more recession and less CAL gain than group B. Non-parametric tests yielded no significant differences in modified plaque index (mPlI) and gingival index (GI) after treatment between both treatment groups. Frequencies and percent distributions of the mPlI and GI scores changed considerably for both treatment groups when compared with the changes in the control group after treatment. With regard to the histological evaluation, no statistical differences existed between the treatments for any linear measurement. The proportion of inflammation found in the mucosal tissues of the control implants was greater than the one found for both treatment groups, P < 0.01. More importantly, both treatment groups showed a similar low proportion of inflammation after 2 months of treatment. CONCLUSIONS: Within the limitations of this experiment, and considering the supportive plaque control rendered, it can be concluded that for pockets of 3-4 mm: (1) mechanical therapy alone or combined with CHX results in the clinical resolution of peri-implant mucositis lesions, (2) histologically, both treatments result in minimal inflammation compatible with health, and (3) the mechanical effect alone is sufficient to achieve clinical and histologic resolution of mucositis lesions
Keratinizing Potential of Sulcular Epithelium
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141308/1/jper0140.pd
Effect of Achromycin Ointment on Healing Following Periodontal Surgery
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141040/1/jper0368.pd
The Reliability of A Colorimetric Test in Determining Gingival Inflammation
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141893/1/jper0564.pd
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