13 research outputs found
Gaura coccinae (Scarlet Butterfly) : Scarlet Butterfly
No full textClass: Dicotyledoneae
Family: Onagraceae
Genus: Gaura
Species: coccina
Malignant melanoma: A retrospective series from a regional cancer center in India
No full textPurpose : To present our experience in treating malignant melanoma
patients. Methods and Materials : All melanoma patients treated at the
Department of Radiotherapy, All India Institute of Medical Sciences,
New Delhi, India, from 1995 to 2007 were studied retrospectively. The
endpoints were loco-regional recurrence, distant recurrence,
recurrence-free survival (RFS), and duration of follow-up (DOFU). RFS
and DOFU were analyzed with respect to the factors like age, sex,
tissue of origin, site of disease, number of nodes, lymphadenopathy,
ulceration, stage, and operability to find out any association.
Results : Seventy-two patients were found evaluable with 40 males and
32 females (median age 46.5 years). Eye was the commonest primary site
with visual disturbance as the commonest symptom. Overall, 87% of the
lesions were single, with most of the nonocular lesions presenting in
the advanced stage. During the disease course, regional lymphadenopathy
and distant metastases were seen in 33% and 32% of cases, respectively.
Highest incidence of lymphadenopathy was seen in skin lesions and in
primaries from trunk and extremities. Of all treated patients, 47%
achieved complete response, 18% partial response, and others had either
stable or progressive disease. The median DOFU was 6.2 months. RFS was
studied only in curatively treated cases with a median of 10 months.
Operability at presentation was the only prognostic factor influencing
DOFU. Conclusion : Malignant melanoma is an uncommon disease in India
carrying a lot of morbidity due to late presentation. Its management is
still not clear regarding the optimum use and schedule of treatment
modalities. More prospective studies in the future are required to come
to a definite conclusion
Malignant melanoma: A retrospective series from a regional cancer center in India
No full textPurpose : To present our experience in treating malignant melanoma
patients. Methods and Materials : All melanoma patients treated at the
Department of Radiotherapy, All India Institute of Medical Sciences,
New Delhi, India, from 1995 to 2007 were studied retrospectively. The
endpoints were loco-regional recurrence, distant recurrence,
recurrence-free survival (RFS), and duration of follow-up (DOFU). RFS
and DOFU were analyzed with respect to the factors like age, sex,
tissue of origin, site of disease, number of nodes, lymphadenopathy,
ulceration, stage, and operability to find out any association.
Results : Seventy-two patients were found evaluable with 40 males and
32 females (median age 46.5 years). Eye was the commonest primary site
with visual disturbance as the commonest symptom. Overall, 87% of the
lesions were single, with most of the nonocular lesions presenting in
the advanced stage. During the disease course, regional lymphadenopathy
and distant metastases were seen in 33% and 32% of cases, respectively.
Highest incidence of lymphadenopathy was seen in skin lesions and in
primaries from trunk and extremities. Of all treated patients, 47%
achieved complete response, 18% partial response, and others had either
stable or progressive disease. The median DOFU was 6.2 months. RFS was
studied only in curatively treated cases with a median of 10 months.
Operability at presentation was the only prognostic factor influencing
DOFU. Conclusion : Malignant melanoma is an uncommon disease in India
carrying a lot of morbidity due to late presentation. Its management is
still not clear regarding the optimum use and schedule of treatment
modalities. More prospective studies in the future are required to come
to a definite conclusion
Carcinoma of the Uterine Cervix Presenting as Superior Vena Cava Syndrome: Report of Three Cases and a Review of Literature
No full textCentral nervous system metastases from primary epithelial ovarian cancer
No full textThis article does not have an abstract
Central nervous system metastases from primary epithelial ovarian cancer
No full textThis article does not have an abstract
Management of extraocular retinoblastoma: icmr consensus guidelines
No full textRetinoblastoma (RB) is the most common intraocular malignancy of childhood. Advanced stage presentation of RB is common in low middle-income countries (LMICs) due to lack of awareness, social taboos associated with enucleation, seeking alternative conservative treatment options, and poor accessibility to health care. Over the last few decades, there have been significant advancements in the management of extraocular RB (EORB) which have improved outcomes and helped in minimizing treatment-related toxicities. The incorporation of multimodality approaches including chemotherapy, surgery, and radiotherapy (RT) has shown promising results; however, prognosis remains poor especially in LMICs. In this article, authors have discussed the ICMR consensus guidelines on the management of EORB, including metastatic RB
Language processing within the striatum: Evidence from a PET correlation study in Huntington's disease
No full textThe role of sub-cortical structures in language processing, and more specifically of the striatum, remains controversial. In line with psycholinguistic models stating that language processing implies both the recovery of lexical information and the application of combinatorial rules, the striatum has been claimed to be involved either in the former component or in the latter. The present study reconciles these conflicting views by showing the striatum's involvement in both language processes, depending on distinct striatal sub-regions. Using PET scanning in a model of striatal disorders, namely Huntington's disease (HD), we correlated metabolic data of 31 early stage HD patients regarding different striatal sub-regions with behavioural scores on three rule/lexicon tasks drawn from word morphology, syntax and from a non-linguistic domain, namely arithmetic. Behavioural results reflected impairment on both processing aspects, while deficits predominated on rule application. Both correlated with the left striatum but involved distinct striatal sub-regions. We suggest that the left striatum encompasses linguistic and arithmetic circuits, which differ with respect to their anatomical and functional specification, comprising ventrally located regions dedicated to rule computations and more dorsal portions pertaining to lexical devices. © The Author (2008). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
