225 research outputs found
Commentary: Central retinal arterial occlusions after phacoemulsification: Our perspective
No full textOutcomes of Collagen Crosslinking in Patients with Keratoconus and Co-Existent Limbal Stem Cell Deficiency
Get PDFRashmi Deshmukh,1 Eeshita Agarwal,1 Swapna Shanbhag,1 Rasik B Vajpayee2– 4 1Shantilal Shanghvi Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India; 2Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia; 3Vision Eye Institute, Melbourne, VIC, Australia; 4University of Melbourne, Melbourne, VIC, AustraliaCorrespondence: Rashmi Deshmukh, LV Prasad Eye Institute, Road Number 2, Banjara hills, Hyderabad, 500084, India, Email [email protected]: To analyse the outcomes of collagen crosslinking (CXL) in eyes with progressive keratoconus (KC) and secondary limbal stem cell deficiency (LSCD) caused by vernal keratoconjunctivitis (VKC).Methods: Patients with progressive KC and VKC having co-existent LSCD who underwent CXL from May 2016 to October 2023 were included. Demographic details, clinical and corneal topography data were collected preoperatively, at 1-months, 3-months, 6-months and 1-year. Details of the CXL procedure and early postoperative complications were noted. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA) and topographic indices including flattest keratometry (K1), steepest keratometry (K2), mean keratometry (Km), maximum keratometry (Kmax) and thinnest corneal thickness (TCT) were noted at 1-year and compared with the preoperative data.Results: Fifteen eyes of 11 patients were included in the study. Partial LSCD was present in 14 eyes and underwent epithelium-off CXL and 1 eye with total LSCD underwent transepithelial CXL. The mean logarithm of the minimum angle of resolution (logMAR) UCVA pre-CXL was 0.67± 0.38 which improved to 0.54± 0.32 at 6-months (p=0.05) and 0.65± 0.35 logMAR at 1-year post-CXL (p = 0.005). Pre-CXL Km was 53.5± 4.77 (median-51.95D) which decreased to post-cxl value of 51.72± 3.65 at 6-months (p=0.014) and 52.34± 3.83 (median-51.3D) at 1-year (p=0.09). Kmax reduced from 63.41± 7.11 (median-63.7D) pre-CXL to 60.65± 5.31 (median-59.6) (p=0.05) at 6-months and 61.4± 6.01 (median-61.9D) at 1-year post-CXL (p=0.115). Of the 14 eyes that underwent epi-off CXL, 2 eyes (14.28%) had persistent epithelial defects (PEDs), one of which needed amniotic membrane graft (AMG).Conclusion: In our series, most eyes with keratoconus having co-existent LSCD had uncomplicated ocular surface healing post-CXL and remained stable at 1-year with significant improvement in visual acuity. Our study shows that CXL can be successfully performed in cases of Keratoconus with co-existing LSCD without any serious complications.Keywords: keratoconus, limbal stem cell deficiency, collagen crosslinking, vernal keratoconjunctiviti
Optimization and control of wind energy systems for grid integration
Get PDFWind energy is a rapidly expanding source of renewable energy, but wind resources are highly intermittent. This makes increasing the level of wind energy penetration in an overall energy portfolio challenging if power quality and grid frequency is to be maintained. In a conventional power system, grid frequency regulation is typically achieved by means of some form of active power control (APC) of power generation plants. Active power control of plant power output aims to maintain the power balance between generation and consumption. Wind turbines have historically not participated in the active power control and are therefore isolated from the grid using sophisticated power electronics, increasing the cost of wind energy. Interest in studying APC of wind turbines for grid frequency regulation has been revived recently. Most of the proposed approaches either focus on single turbine, or overlook the effect of APC strategies on actuator usage and mechanical loading of the system. However, wind energy based power generation plants have an array of wind turbines that interact with each other aerodynamically in a complicated manner. In this work we introduce a new distributed APC strategy in which a farm level controller optimally distributes the task of regulation to all the wind turbines in a farm accounting for dynamic wake effects introduced due to control actions of each of those wind turbines. An individual model predictive controller at each wind turbine then tracks the power references passed on by farm level controller, subject to mechanical loading constraints. The results from this approach are compared with the greedy approach when the individual wind turbines only optimize their own power production without consideration of downstream neighbors. We then extend the idea of this hierarchical control to co-optimization of wind farms and battery energy storage for regulation, and then for simultaneous wind farm layout and control design to exploit the synergy between layout design and wind farm control.
We show that the regulation performance scores for the distributed APC approach are statistically significantly better than the greedy approach. We also show that co-optimization of wind farm and battery energy storage provides significantly superior performance over baseline, for a much smaller battery capacity, providing a potentially significant cost saving. Finally, we show that designing a layout with simultaneous consideration of control system design, allows us harness synergistic relationships between layout and control. Capitalizing on these synergy mechanisms enables increased annualized wind farm energy production.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2019-05-01The student, Anand Deshmukh, accepted the attached license on 2017-02-02 at 12:49.The student, Anand Deshmukh, submitted this Dissertation for approval on 2017-02-02 at 12:58.This Dissertation was approved for publication on 2017-02-02 at 16:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #10553 on 2017-08-10 at 15:04:23Made available in DSpace on 2017-08-10T20:32:27Z (GMT). No. of bitstreams: 2
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Study On Ponderal Index Of Fish Puntius sarana(Hamilton) From Godavari River, At Nanded, Maharashtra State, India
No full textAbstract: Study of Ponderal index of freshwater fish Puntius sarana(Hamilton), from Godavari River, at Nanded, Maharahtra State were observed from April 2015 to March 2016. The obtained results indicate that population of Puntius sarana is better in condition throughout the year even in spawning season. LeCren (1951) remarks “The ponderal index forms an important part of fishery research and has often been issued to provide additional information about spawning, feeding and other aspects related to the well being of a fish. Several other workers have been made investigations on the condition factor of different species and correlated the variation in ‘K’ values with various factor in life of fish. Hickling (1930,1940), Hile (1936), Thompson (1943), Menon (1950), LeCren (1951) have correlated the ponderal index with spawning cycle and feeding intensity in Johnius dussmieri. Review of literature shows there is no information regarding the ponderal index of Puntius sarana. Therefore the present investigation was undertaken with a view to study the ponderal index of this fish.
Keywords: fish Puntius sarana(Hamilton), Godavari River, spawning season, ponderal index.
Title: Study On Ponderal Index Of Fish Puntius sarana(Hamilton) From Godavari River, At Nanded, Maharashtra State, India
Author: Deshmukh M.M., Shillewar K.S.
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
Vol. 10, Issue 2, April 2022 - June 2022
Page No: 41-43
Research Publish Journals
Website: www.researchpublish.com
Published Date: 09-June-2022
DOI: https://doi.org/10.5281/zenodo.6627906
Paper Download Link (Source)
https://www.researchpublish.com/papers/study-on-ponderal-index-of-fish-puntius-saranahamilton-from-godavari-river-at-nanded-maharashtra-state-indiaInternational Journal of Life Sciences Research, ISSN 2348-313X (Print), ISSN 2348-3148 (online), Research Publish Journals, Website: www.researchpublish.co
Optimal Placement and Sizing of Distributed Generator in Distribution System Using Artificial Bee Colony Algorithm
No full textElucidation and modeling of the in-vivo kinetics of enzymes and membrane transporters associated with β-lactam and non-ribosomal peptide production in Penicillium chrysogenum
No full textEven 80 years after the discovery of penicillin, it still holds 16% of total antibiotics market. This makes it crucial, from an economical point of view, to improve our understanding of the production organism Penicillium chrysogenum to maximize the penicillin production, as its theoretical yields are far from reached. With the advancement in analytical techniques and detailed knowledge of the metabolic pathways, enough information and tools are available to try to identify possible bottlenecks that limit the penicillin yield, and thus with known genome sequence there are possibilities to modify the strain by using metabolic engineering strategies. One of the aims of this study was to unravel the in vivo enzyme kinetic properties and identify possible bottlenecks in the penicillin biosynthesis pathway in Penicillium chrysogenum. To understand the mechanism of the enzymes/transporters under in vivo conditions and to estimate parameters, several different studies were carried out that included steady state and stimulus response experiments. The other aim of the study was to use Penicillium chrysogenum as a cell factory to produce non-ribosomal peptides. The strain used was an industrial high producing strain.BiotechnologyApplied Science
Adaptive Modularity for Power Electronics Based Electrolysis Systems for Green Hydrogen
No full textElectrolysis holds tremendous potential in reducing the carbon footprint and providing energy dense fuels such as methane. Such systems can be integrated with renewable energy systems with the aid of power electronics interfaces. However, this integration is not straight-forward and imposes various converter design challenges. This paper presents the current state-of-the-art electrolyzer systems, and a simple model of an alkaline regenerative stack with four degrees of freedom. To gain insights with regards to limitations/trade-offs, a sensitivity analysis is conducted on this model. Based on these insights, the challenges associated with power electronics converter design for this application have been discussed along with the trade-offs associated with the electrolyser system. Furthermore, the concept of adaptive modularity for efficiency and reliability improvement has been discussed.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.DC systems, Energy conversion & Storag
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