86,511 research outputs found

    Treatment options for oral Leukoplakia: a review

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    Aim: the aim of this work was to highlight the most important findings regarding treatment options for oral leucoplakia, a white lesion with a potentially malignant evolution. There are several forms of oral leukoplakia with a various rate of malignant transformation, related to alcohol and tobacco consumption, gender, population, lesion size and type and level of dysplasia. Methods: two databases (Medline via PubMed, Web of Science) were searched up to July 2022 and the most relevant papers on the topic were selected. Hand search was carried out too focusing on new and promising techniques regarding oral leukoplakia management options. Only papers written in English or Spanish were included in the research. Results: the management options for oral leukoplakia are varied and diverse, they may involve a regime of observation with use of new and promising salivary biomarkers, a topical or systemic use of drugs, a surgical approach including laser ablation or a non-surgical approach using photodynamic therapy (PDT). There is a rising interest in PDT, which proved to be an interesting minimally invasive approach for oral leukoplakia, reducing lesions size or removing the lesion in its totality, de-pending on the histopathological stage of the lesions and other variables linked to the type of PDT and the number of sessions. PDT works through the interaction between a light source and a chemical dye or photosensitizer in the presence of oxygen resulting in the formation of reactive oxygen species (ROS), which cause oxidative damage. Conclusions: despite promising results, longer clinical trials are required in order to define a protocol, evaluate potential side effects of PDT and demonstrate its effectiveness

    Germectomy of the third molar in orthodontics: a review of the literature

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    Aim: germectomy is a surgical treatment defined as the removal of a tooth at the beginning of its development, when it has no contacts with the surrounding anatomical structures. The aim of the work is to present an in-ternational literature re-view to offer an overview on indications and ideal timing for this practice. Methods: a literature review has been done on PubMed database [www.ncbi.nim.nih.gov/pubmed] looking for the articles dealing with indications, contraindications, and discussions about this technique. Among the arti-cles found, those ones published between 2013 and 2023 were selected. Results: germectomy is a convenient, rapid, atraumatic technique without important post-surgical side effects. It's executable in local anaesthesia and it's much less invasive than the traditional surgery of the third molar: for this reason, a lot of authors are favorable to this practice. Among the authors, the debate about the ideal timing to operate is still open. Conclusions: despite the conflicting opinions found in the literature, it's univocally recognized the importance of a careful evaluation of each single patient, in order to establish/decide the real need of germectomy and the right period to operate

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    [Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]

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    Newspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.

    Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation

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    The desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters

    John F. Kennedy telegram to Roosevelt

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    Jersey Homesteads (later the Borough of Roosevelt) was established in the 1930s as an agro-industrial cooperative community. It was established specifically for urban Jewish garment workers, many of whom had emigrated from Europe. President John F. Kennedy sent a telegram to the citizens of Roosevelt, New Jersey, apologizing for not being able to attend the memorial dedication in honor of former President Franklin Delano Roosevelt. (Jersey Homesteads became Roosevelt in 1945 in honor of the president.) President Kennedy expressed his gratitude to the people of Roosevelt for constructing the memorial, and commented that it will serve as a constant reminder of Roosevelt's good works

    Logarithmic variance profiles and the corresponding f-1 spectra of temperature fluctuations in turbulent Rayleigh-Bénard convection

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    We report experimental results for the temperature variance 2(z) and the corresponding frequency spectra P(f) in turbulent Rayleigh-Bénard convection (RBC) in a cylindrical sample of aspect ratioT= D/L = 1:00 (D = 1:12 m is the diameter and L = 1:12 m the height). The measurements were conducted in the Rayleigh-number range 1011 < Ra < 1:35 1014 and Pr ' 0:8. For Ra = 1:35x1014, 2(z) could be described well by a logarithmic dependence on the vertical position z in a range of z 1 < z < z 2 with z 1 ' 70 and z 2 = 0:1L. Here L=(2Nu) is the thickness of a thin thermal sublayer adjacent to the horizontal plate where the heat flux (denoted by the Nusselt number Nu) is carried mostly by thermal diffusion. In the log layer, we found that the temperature spectra had a significant frequency range over which P(f) f with close to 1. As Ra decreased, increased so that the log layer became thinner. At Ra = 2:05 1011, z 2 < z 1 and therefore there was no range for a log layer. Correspondingly, the temperature spectrum near the horizontal plate did not have the f1 scaling form either

    Maine author Franklin F. Gould recalls his first glimpse of the outside world

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    Maine author Franklin F. Gould recalls his first glimpse of the outside world as he relates how, as a young farm boy in the late 1800\u27s, he drove his father\u27s horses on an errand to an icebound river
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