1,721,440 research outputs found
Establishing a National Cardiac Amyloidosis Network: the case of Italy
No full textNegli ultimi 10 anni molte cose sembrano cambiate in tema di amiloidosi. Due esempi: nel principale centro del Regno Unito dedicato alla cura dell’amiloidosi, il National Amyloidosis Centre (NAC) di Londra, il numero di diagnosi di amiloidosi da transtiretina (ATTR) ha avuto un andamento esponenziale dal 2008 ad oggi2. Per quanto riguarda in particolare la forma “wild-type”, il numero di nuove diagnosi per anno è stato mediamente di 120, sino a raggiungere un valore complessivo nel 2019 di 711. Se si considera il più grande registro internazionale dedicato alla ATTR (il registro THAOS) e si limita l’analisi ai Centri che arruolavano pazienti già ai suoi inizi (nel 2007), si osserva un aumento dei casi da 176 a 2176
EXPLORER-HCM: il mavacamten nel trattamento della cardiomiopatia ipertrofica ostruttiva sintomatica
No full textN
Commentary: What is the relationship between Covid-19 and cardiovascular disease?
No full textCommentary: What is the relationship between Covid-19 and cardiovascular disease
The difficult diagnosis of isolated cardiac sarcoidosis: usefulness of an integrated MRI and PET approach
No full textA 54-year-old Caucasian woman was admitted to the emergency department of a peripheral hospital for palpitations. ECG showed a wide QRS complex tachycardia that resolved spontaneously (figure 1A). Clinical history was negative. At echocardiogram, hypokinesia and thinning of basal septum and mild pericardial effusion were the only abnormal findings (see online supplementary videos 1 and 2). Left ventricular (LV) ejection fraction (EF) was 55%. Coronary arteries were normal at coronary angiography. Chest x-ray was normal. At electrophysiological study ventricular tachycardia with the same morphology encountered at presentation was inducible
2019 CORONAVIRUS: What are the implications for cardiology?
No full textIt is the third time, in recent decades, that a zoonotic coronavirus has crossed species to infect human beings. Seventeen years ago, an outbreak of a virus whose RNA sequences closely resemble those of a virus that silently circulates in bats – the so-called “SARS-CoV” – caused severe acute respiratory syndrome with a fatality rate of 9 to 11%. A few years later (2012), the Middle East respiratory syndrome coronavirus – the so-called “MERS-CoV” – had a fatality rate of 34%. For both viruses, age and coexisting conditions such as diabetes or heart disease were independent predictors of adverse outcome
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