9 research outputs found
Reno productive activity of Ipomoea digitata in gentamicin induced kidney dysfunction
No full textKidneys endowed with million units termed as “nephrons†that act as natural sieves. The kidneys provide the final common pathway for the excretion of many drugs and their metabolites and therefore are frequently subjected to high concentrations of potentially toxic substances. Administration of several antibiotics like Gentamicin causes kidney dysfunction. Rats treated with Gentamicin developed significant kidney dysfunction was observed from increased level of urea, creatinine, sodium and decreased level of protein, potassium and non enzymatic antioxidants such as vitamin C and vitamin E. The plant, Ipomoea digitata is found to have nephroprotective activity. --------------------------------------------------------------------------------------------------------*Department of Biochemistry and Chemistry, Faculty of Science, PRIST University, Vallam, Tanjavur – 613 403, Tamilnadu, India**Department of Zoology, Annamalai University, Annamalainagar - 608 002, Tamilnadu, India1Corresponding author, Email: [email protected] This Article As: A. Kalaiselvan, T. Anand and M. Soundararajan.Reno productive activity of Ipomoea digitata in gentamicin induced kidney dysfunction. J. Ecobiotechnol. 2(2): 57-62
Aetiology, Management and Prognosis of Jaundice in Adult Patients With Acute Severe Intestinal Failure
No full textSelection of suitable biomass conservation process techniques: a versatile approach to normal wiggly interval-valued hesitant fuzzy set using multi-criteria decision making
No full textAbstract A country that relies on developing industrialization and GDP requires a lot of energy. Biomass is emerging as one of the possible renewable energy resources that may be used to generate energy. Through the proper channels, such as chemical, biochemical, and thermochemical processes, it can be turned into electricity. In the context of India, the potential sources of biomass can be broken down into agricultural waste, tanning waste, sewage, vegetable waste, food, meat waste, and liquor waste. Each form of biomass energy so extracted has advantages and downsides, so determining which one is best is crucial to reaping the most benefits. The selection of biomass conversion methods is especially significant since it requires a careful study of multiple factors, which can be aided by fuzzy multi-criteria decision-making (MCDM) models. This paper proposes the normal wiggly interval-valued hesitant fuzzy-based decision-making trial and evaluation laboratory model (DEMATEL) and the Preference Ranking Organization METHod for Enrichment of Evaluations II (PROMETHEE) for assessing the problem of determining a workable biomass production technique. The proposed framework is used to assess the production processes under consideration based on parameters such as fuel cost, technical cost, environmental safety, and C O 2 emission levels. Bioethanol has been developed as a viable industrial option due to its low carbon footprint and environmental viability. Furthermore, the superiority of the suggested model is demonstrated by comparing the results to other current methodologies. According to comparative study, the suggested framework might be developed to handle complex scenarios with many variables
Incidence of perforated gastrojejunal anastomotic ulcers after laparoscopic gastric bypass for morbid obesity and role of laparoscopy in their management
No full textIntuitionistic fuzzy MAUT-BW Delphi method for medication service robot selection during COVID-19
No full textCoronavirus Disease 2019 (COVID-19), a new illness caused by a novel coronavirus, a member of the corona family of viruses, is currently posing a threat to all people, and it has become a significant challenge for healthcare organizations. Robotics are used among other strategies, to lower COVID’s fatality and spread rates globally. The robot resembles the human body in shape and is a programmable mechanical device. As COVID is a highly contagious disease, the treatment for the critical stage COVID patients is decided to regulate through medication service robots (MSR). The use of service robots diminishes the spread of infection and human error and prevents frontline healthcare workers from exposing themselves to direct contact with the COVID illness. The selection of the most appropriate robot among different alternatives may be complex. So, there is a need for some mathematical tools for proper selection. Therefore, this study design the MAUT-BW Delphi method to analyze the selection of MSR for treating COVID patients using integrated fuzzy MCDM methods, and these alternatives are ranked by influencing criteria. The trapezoidal intuitionistic fuzzy numbers are beneficial and efficient for expressing vague information and are defuzzified using a novel algorithm called converting trapezoidal intuitionistic fuzzy numbers into crisp scores (CTrIFCS). The most suitable criteria are selected through the fuzzy Delphi method (FDM), and the selected criteria are weighted using the simplified best–worst method (SBWM). The performance between the alternatives and criteria is scrutinized under the multi-attribute utility theory (MAUT) method. Moreover, to assess the effectiveness of the proposed method, sensitivity and comparative analyses are conducted with the existing defuzzification techniques and distance measures. This study also adopt the idea of a correlation test to compare the performance of different defuzzification methods
Patient perception of telephone follow-up after resection for colorectal cancer: Is it time for an alternative to the out-patient clinic?
No full textThe economic reality of modern healthcare provides a timely reminder to clinicians of their duty to provide outstanding and cost-effective care. Although multiple guidelines outline investigation, management and surveillance of colorectal cancer, none advocate a particular delivery method. Nurse-led telephone follow-up in multiple specialties has demonstrated equivalent clinical outcomes and patient satisfaction when compared to traditional outpatient department follow-up. This paper aims to compare nurse-led telephone and outpatient follow-up, following surgical resection of colorectal cancer (CRC), focusing on patient perceptions. This cross-sectional study distributed adapted patient satisfaction questionnaire (PS-Q 18) to patients undergoing surveillance following CRC resection via either nurse-led telephone clinics (TC) or standard outpatient department appointments (OPD). 161 questionnaires were distributed (100 OPD, 61 TC); the response rate was 70% for the OPD group, and 87% for the TC group (p=0.02). There was no statistically significant difference between patient reported satisfaction or in preference for healthcare delivery system between groups. More patients in the TC group had serum CEA measured than OPD group. This survey demonstrates high patient satisfaction with telephone follow-up. Owing to the financial benefits on both a patient and healthcare provider level, as well as improved screening uptake (CEA) in our study, a role for this innovative specialist nurse-led telephone clinic clearly exists. The benefits of telephone follow-up in terms of health economics, health equity and adherence to screening protocols support its exclusive role in long-term CRC surveillance
Su1989 - Severe Gastrointestinal Dysmotility Related Intestinal Failure: Chronic Intestinal Pseudo-Obstruction, Enteric Dysmotility or a ‘Pragmatic’ Approach? Experience from a UK National Referral Centre
No full textCharacterisation of older patients that require, but do not undergo, emergency laparotomy:a multicentre cohort study
No full textBackgroundOlder adults (≥65 yr) account for the majority of emergency laparotomies in the UK and are well characterised with reported outcomes. In contrast, there is limited knowledge on those patients that require emergency laparotomy but do not undergo surgery (NoLaps).MethodsA multicentre cohort study (n=64 UK surgical centres) recruited 750 consecutive NoLap patients (February 15th - November 15th 2021, inclusive of a 90-day follow up period). Each patient was admitted to hospital with a surgical condition treatable by an emergency laparotomy (defined by The National Emergency Laparotomy Audit (NELA) criteria), but a decision was made not to undergo surgery (NoLap).ResultsNoLap patients were predominately female (452 patients, 60%), of advanced age (median age 83.0 yr, interquartile range 77.0–88.8), frail (523 patients, 70%), and had severe comorbidity (750 patients, 100%); 99% underwent CT scanning. The commonest diagnoses were perforation (26%), small bowel obstruction (17%), and ischaemic bowel (13%). The 90-day mortality was 79% and influencing factors were >80 yr, underweight BMI, elevated serum lactate or creatinine concentration. The majority of patients died in hospital (77%), with those with ischaemic bowel dying early. For the 21% of NoLap patients that survived to 90 days, 77% returned home with increased care requirements.ConclusionsThis study reports that the NoLap patient population present significant medical challenges because of their extreme levels of comorbidity, frailty, and physiology. Despite these complexities a fifth remained alive at 90 days. Further work is underway to explore this high-risk decision-making process
