90 research outputs found

    OPTIMALISASI PERAWATAN GRAB DALAM KELANCARAN BONGKAR MUAT CLINKER DI MV. SHANTHI INDAH

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    ABSTRAKSI Romario Anugerah Agung. G, 51145454 T, “Optimalisasi perawatan grab dalam kelancaran bongkar muat clinker di MV. Shanthi Indah” Program Diploma IV, Teknika, Politeknik Ilmu Pelayaran Semarang, Pembimbing:(1)Capt. H. Agus Subardi, M.Mar (2)Drs. Darjono, M.Mar.E Agar pengangkutan barang dari pelabuhan muat ke pelabuhan bongkar bisa tepat waktu sesuai dengan jadwal yang telah diperkirakan, salah satu faktor penting agar proses pemuatan berjalan lancar adalah kondisi alat muat bongkar. Berdasarkan fakta ditemukan, penulis tertarik untuk membuat skripsi dengan judul “Optimalisasi perawatan grab dalam kelancaran bongkar muat clinker di mv. Shanthi indah”.Dalam penelitian ini penulis menggunakan metode Swot dan Hassop yang menghasilkan data kuantitatif berupa kata-kata tertulis dari orangorang dan perilaku yang diamati dengan mengumpulkan data berupa pendekatan terhadap obyek melalui observasi, wawancara secara langsung terhadap subyek serta menggunakan dokumen dan data yang yang berhubungan dengan perawatan alat muat bongkar. Hal ini bermaksud untuk mengetahui beberapa hal yang berkaitan mengenai perawatan grab. Dalam melaksanakan perawatan grab, ada permasalahan yang dibahas seperi bagaimana pengaruh perawatan grab yang tidak tepat terhadap kelancaran kegiatan muat bongkar dipelabuhan. Sesuai dengan permasalahan yang timbul dalam melaksanakan perawatan alat muat bongkar, muncul jawaban sementara atas masalah yang dikemukakan, diantaranya : diduga bahwa penyebab masalah yang dialami oleh alat bongkar muat dikapal MV. Shanthi Indah disebabkan oleh kurangnya perawatan alat bongkar muat dikapal sehingga dapat menghambat proses muat bongkar. Dari hasil analisa yang dilakukan penulis, dapat disimpulkan bahwa peralatan bongkar muat harus dirawat secara teratur diantaranya dengan menggunakan metode perawatan. Metode perawatan alat bongkar muat tersebut harus dilaksanakan dengan baik dan teratur sesuai dengan jadwal yang telah diprogramkan, agar kerusakan-kerusakan pada alat bongkar muat dapat dihindari dan alat siap digunakan untuk proses pembongkaran dan pemuatan. ABSTRACT Romario Augerah Agung. G, 51145454 T, “Optimazion of Maintenace Grab in the Straight of the Budget to Clinker in the MV. Shanthi Indah” Program Diploma IV, Technical, Marchant Marine Polytechnic of Semarang, 1st Supervision: H. IRWAN,SH, M.Pd M.Mar.E (2) and 2nd Supervision: Capt. Arika Palapa, M. Si, M. Mar In order to transport goods from the loading port to the loading port, it can be on time according to the estimated schedule, one of the important factors so that the loading process runs smoothly is the condition of the loading and unloading equipment. Based on the facts found, the author was interested in making a thesis with the title "Optimizing grab care in the smooth loading and unloading of clinkers in mv. Beautiful Shanthi ". In this study the author uses the Swot and Hassop method that produces quantitative data in the form of written words from people and behavior observed by collecting data in the form of an approach to objects through observation, interviews directly with the subject and using documents and data related to maintenance of loading and unloading equipment. This means to find out some things related to the care of grab. In carrying out grab maintenance, there are problems that are discussed such as how the effects of grab care are inappropriate on the smooth operation of loading and unloading at the port. In accordance with the problems that arise in carrying out loading and unloading maintenance, a temporary answer arises from the problems raised, including: it is alleged that the cause of the problem experienced by the loading and unloading equipment is the MV. Shanthi Indah is caused by the lack of maintenance of loading and unloading equipment in the ship so that it can hinder the loading and unloading process. From the results of the analysis carried out by the author, it can be concluded that loading and unloading equipment must be treated regularly including using treatment methods. The method of handling loading and unloading equipment must be carried out properly and regularly in accordance with the programmed schedule, so that damage to the loading and unloading equipment can be avoided and the tool is ready to be used for the process of dismantling and loading

    ANALISIS TIDAK SEMPURNANYA PENGABUTAN INJEKTOR PADA AUXILIARY ENGINE DI MV. SHANTHI INDAH

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    ABSTRAKSI Muhammad Ilham Basyar, 2019, NIT: 52155747.T, “Analisis tidak sempurnanya pengabutan pada auxiliary engine di MV. Shanthi Indah”, skripsi Program Studi Teknika, Program Diploma IV, Politeknik Ilmu Pelayaran Semarang, Pembimbing I: Wiratno, MT,M.Mar. E, Pembimbing II: Srisuyanti, SS Auxiliary Engine adalah mesin dimana udara dikompres ke suhu yang cukup tinggi untuk menyalakan bahan bakar diesel yang disuntikkan ke dalam silinder, di mana pembakaran dan pemancaran menggerakkan piston yang mengubah energi kimia yang dalam bahan bakar menjadi energi mekanik. pengabutan yang baik sangat diperlukan pada mesin diesel, guna mendapatkan tenaga yang maksimal. Kondisi injektor pada Auxiliary Engine sangat berpengaruh terhadap kondisi Auxiliary Engine itu sendiri. Adanya kerusakan injektor dapat mempengaruhi kondisi dari pengoperasian Auxiliary Engine, sehingga kondisi injektor harus selalu dijaga. Metode penelitian yang penulis gunakan dalam penyusunan skripsi ini adalah metode penelitian penggabungan antara metode fault tree analysis dan fishbone sebagai teknik analisa data untuk menganalisa masalah yang ada pada Auxiliary Engine, yaitu faktor-faktor apakah yang menyebabkan kerusakan injektor pada Auxiliary Engine, dampak dan upaya apa yang dilakukan untuk mengatasi faktor–faktor dari permasalahan tersebut dengan mengidentifikasi berbagai faktor-faktor secara sistematis terhadap faktor manusia (Man), Lingkungan (Mother nature), Metode(Methode), Mesin (Machine) untuk merumuskan strategi yang akan diambil. Berdasarkan hasil penelitian yang telah dilakukan penulis di kapal MV. Shanthi Indah pada tanggal 13 Agustus 2017 sampai dengan 14 Agustus 2018, dapat disimpulkan bahwa kerusakan injektor pada Auxiliary Engine disebabkan oleh dua faktor, yaitu 1) jadwal operasional kapal yang tinggi, dan jarangnya dilakukan perawatan pada injektor Auxiliary Engine. 2) penggunaan bahan bakar yang tidak sesuai. Untuk mengatasi faktor-faktor tersebut dapat dilakukan perawatan sesuai waktu PMS, serta dilakukan penyaringan yang baik pada bahan bakar berkualitas rendah. ABSTRACT Muhammad Ilham Basyar, 2019, NIT: 52155747.T, "Analysis of incomplete removal on the auxiliary engine in the MV. Shanthi Indah ", Thesis of Engineering Study Program, Diploma IV Program, Semarang Shipping Science Polytechnic, Advisor I: Wiratno, MT, M.Mar. E, Advisor II: Srisuyanti, SS The Auxiliary Engine is a machine in which air is compressed to a temperature high enough to ignite diesel fuel injected into a cylinder, where combustion and transmission drive a piston that converts chemical energy in the fuel to mechanical energy. good removal is needed on diesel engines, in order to get maximum power. The injector conditions at the Auxiliary Engine greatly influence the condition of the Auxiliary Engine itself. The presence of injector damage can affect the conditions of the operation of the Auxiliary Engine, so the injector condition must always be maintained. The research method that I use in the preparation of this paper is a research method that combines the fault tree analysis and fishbone methods as a data analysis technique to analyze the problems that exist in the Auxiliary Engine, namely what factors cause damage to the injector at the Auxiliary Engine, what impact and effort done to overcome the factors of the problem by identifying various factors systematically to the human factor (Man), Environment (Mother nature), Method (Method), Machine (Machine) to formulate the strategy to be taken. Based on the results of research conducted by the author on the MV. Shanthi Indah on August 13, 2017 to August 14, 2018, it can be concluded that the injector damage to the Auxiliary Engine is caused by two factors, namely 1) the ship's operational schedule is high, and the maintenance of the Auxiliary Engine injector is rare. 2) inappropriate use of fuel. To overcome these factors, maintenance can be carried out according to the PMS time, and good filtration of low-quality fuel is carried out

    PENANGANAN KERUSAKAN MACHINERY HATCH COVER HYDRAULIC UNTUK MEMPERLANCAR BONGKAR MUAT PENANGANAN KERUSAKAN MACHINERY HATCH COVER HYDRAULIC UNTUK MEMPERLANCAR BONGKAR MUAT PENANGANAN KERUSAKAN MACHINERY HATCH COVER HYDRAULIC UNTUK MEMPERLANCAR BONGKAR MUAT BATU BARA DI MV. SHANTHI INDAH

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    ABSTRAK Agung Tri Widodo, 2019, NIT: 52155554. N, ‘’Penanganan Kerusakan Machinery Hatch Cover Hydraulic Untuk Memperlancar Bongkar Muat Batu Bara di MV. Shanthi Indah”, Skripsi Program Studi Nautika, Program Diploma IV, Politeknik Ilmu Pelayaran Semarang, Pembimbing I: Capt. Eko Murdiyanto, M.Pd., M.Mar., dan Pembimbing II : Capt. Firdaus Sitepu, S.ST, M.Si, M.Mar Dimana transportasi laut memiliki peran yang sangat vital bagi pembangunan bangsa sehingga kapal niaga menjadi sarana pilihan bagi perusahaan pemerintah maupun perusahaan swasta dalam menjalankan roda perekonomian. MV. Shanthi Indah sendiri adalah salah satu kapal curah yang mengangkut batu bara yang dikelola oleh PT.KSE (Karya Sumber Energy), milik warga negara indonesia sendiri yang beroperasi diwilayah indonesia maupun internasional. Sehingga peralatan bongkar muat diatas kapal MV.Shanthi Indah sangat penting untuk diperhatikan maka penulis merusmuskan masalah yaitu pananganan kerusakan machinery hatch cover hydraulic dan dampak kerusakan machinery hatch cover hydraulic untuk menjadi acuan dalam penelitian ini agar menjadi pembatas dalam membuat sebuah penelitian ini. Machinery hatch cover hydraulic adalah salah satu alat yang perannya sangat vital untuk kapal curah, terutama untuk kapal curah dengan jenis palka berupa melipat. Mesin palka hydrolik berfungsi untuk mengangkat roda pada palka dengan menggunakan cairan minyak hydrolik yang dimampatkan melalui pipe hydraulic dan di teruskan ke jack hydraulic agar palka dapat terbuka. Penelitian ini menggunakan metode deskriptif kualitatif dengan mendeskripsikan secara terperinci saat pelaksanaan kegiatan bongkar/muat yang tertunda karena terjadinya kerusakan machinery hatch cover hydraulic di kapal MV. Shanthi Indah. Pengumpulan data melalui wawancara, observasi, studi pustaka, dan dokumentasi saat dikapal. Tekhnik pengolahan data yang digunakan adalah fishbone analysis dan fault tree analysis. Hasil penelitian menunjukkan bahwa penyebab terjadinya kerusakan machinery hatch cover hydraulic di MV. Shanthi Indah adalah kotornya oil filter pada mesin yang menyebabkan cepatnya high pressure sehingga pipa hydrolik dapat pecah. Upaya penanganan kerusakan machinery hatch cover hydraulic adalah melakukan pengecekan dan perawatan secara teratur dan berkala serta memberikan pengarahan kepada crew tentang pengoperasian mesin palka hydrolik saat membuka palka dengan benar dan melakukan pengecekan oil filter pada machinery hatch cover hydraulic yang sudah kotor. ABSTRACT Agung Tri Widodo, 2019, NIT: 52155554.N,‘’The Handling Damage of Machinery Hatch Cover Hydraulic to the Effectiveness Coal of Loading and Unloading Processon MV. Shanthi Indah”, Essay of Nautical Department, Diploma IV Program, Politeknik Ilmu Pelayaran Semarang, 1 st guide: Capt. Eko Muriyanto, M.Pd., M.Mar., And 2 guide: Capt. Firdaus Sitepu, S.ST., M.Si., M.Mar. Where sea transportation has a very vital role for nation building so that commercial vessels become the choice tool for government companies and private companies to run the economy. MV. Shanthi Indah itself is one of the bulk carriers that transport coal managed by PT. ESE (Karya Sumber Energy), which is owned by Indonesian citizens who operate in the Indonesian and international regions. So that the loading and unloading equipment above the MV. Shanthi Indah vessel is very important to note, the author resolved the problem, namely the handling of damage to hydraulic engine hatch cover and the impact of damage to hydraulic cover hatch machinery to be a reference in this study to be a limitation in making this research. Machinery Hatch Cover Hydraulic is one of the tools whose role is very vital for bulk carriers, especially for folding bulk carriers. Hydraulic hatch machine serves to lift the wheel in the hold by using hydraulic oil fluid compressed through a hydraulic pipe and forwarded to a hydraulic jack so that the hold can be opened. This study uses a qualitative descriptive method by describing in detail when the loading or unloading activities are delayed due to damage to the hydraulic engine hatch cover on the MV. Shanthi Indah. Collecting data through interviews, observation, library research, and documentation when on board. Data processing techniques used are fishbone analysis and fault tree analysis The results showed that the cause of the damage to the hydraulic engine hatch cover in the MV. Shanthi Indah is a dirty oil filter on the machine which causes high pressure so that the hydraulic pipe can break. Efforts to deal with damage to hydraulic hatch cover machinery are to check and maintain regularly and periodically and provide guidance to the crew about the operation of the hydraulic hatch machine when opening the hatch correctly and checking the oil filter on the dirty hydraulic engine hatch cover n

    www.omicsonline.com Research Article JCSB/Vol.2 January-February 2009 Role of the Cation-π Interaction in Therapeutic Proteins: A Comparative Study with Conventional Stabilizing Forces

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    Copyright: © 2009 Shanthi V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The cation-π interaction is an important, general force for molecular recognition in biological receptors. In this study, we have analyzed the energy contribution resulting from cation-π interactions in the set of therapeutic proteins. The contribution of cation-π interacting residues in secondary structure involvement, solvent accessibility, stabilization centers, stabilizing residues and conservation score has been evaluated. Secondary structure of the cation-π involving residues shows that, Arg and Lys prefers to be in strand. Among the π residues, Phe prefer to be in coil, Tyr prefers to be in strand and Trp prefer to be in helix. Among the cation-π interacting residues Arg and Lys were in the exposed regions. Phe and Tyr were in the partially buried region and Trp in the fully buried region. Stabilization centers for these proteins showed that all the five residues found in cation-π interactions are important in locating one or more of such centers. The contribution of stabilizing residues in the cation–π interactions was analyzed. Further, the study shows that, 43 percent of the amino acid residues that ar

    Designing Novel Compounds for the Treatment and Management of RET-Positive Non-Small Cell Lung Cancer—Fragment Based Drug Design Strategy

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    Rearranged during transfection (RET) is an oncogenic driver receptor that is overexpressed in several cancer types, including non-small cell lung cancer. To date, only multiple kinase inhibitors are widely used to treat RET-positive cancer patients. These inhibitors exhibit high toxicity, less efficacy, and specificity against RET. The development of drug-resistant mutations in RET protein further deteriorates this situation. Hence, in the present study, we aimed to design novel drug-like compounds using a fragment-based drug designing strategy to overcome these issues. About 18 known inhibitors from diverse chemical classes were fragmented and bred to form novel compounds against RET proteins. The inhibitory activity of the resultant 115 hybrid molecules was evaluated using molecular docking and RF-Score analysis. The binding free energy and chemical reactivity of the compounds were computed using MM-GBSA and density functional theory analysis, respectively. The results from our study revealed that the developed hybrid molecules except for LF21 and LF27 showed higher reactivity and stability than Pralsetinib. Ultimately, the process resulted in three hybrid molecules namely LF1, LF2, and LF88 having potent inhibitory activity against RET proteins. The scrutinized molecules were then subjected to molecular dynamics simulation for 200 ns and MM-PBSA analysis to eliminate a false positive design. The results from our analysis hypothesized that the designed compounds exhibited significant inhibitory activity against multiple RET variants. Thus, these could be considered as potential leads for further experimental studies

    Single umbilical artery

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    The umbilical cord usually contains two arteries and one vein. The vein carries the oxygenated blood from the placenta to the fetus. The arteries carry the deoxygenated blood and the waste products from the fetus to the placenta. Occasionally, primary agenesis or secondary atrophy of one of the arteries occurs resulting in single umbilical artery
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