11 research outputs found
Molecular cloning and sequence of retinoid X receptor in the green crab Carcinus maenas: a possible role in female reproduction
Retinoid X receptor (RXR) belongs to an ancient superfamily of nuclear hormone receptors, and plays an important role in reproduction of vertebrates. However, the reproductive role of RXR has not been clarified in crustaceans. In this investigation, we first report the cloning of two alternative splice variants of RXR cDNA from green crab ovarian RNA. RXR mRNA levels were quantified in different vitellogenic stages of the crab hepatopancreas (HP) and ovary. The expression of RXR mRNA relative to the arginine kinase mRNA was significantly increased in the HP of vitellogenic crabs in a stage-dependent manner. The relative levels of RXR mRNA in the ovary were significantly lower in vitellogenic stage III crabs than in crabs in the other three stages. These data indicate that the HP and ovary of the crab are capable of expressing RXR, which may regulate, in part, vitellogenesis in the crab. We also examined the effects of methyl farnesoate (MF) and RXR-dsRNA treatments on vitellogenin and RXR gene expression. Vitellogenin and RXR mRNA levels in HP and ovarian fragments incubated in MF were significantly (P<0.001) higher than in control tissue fragments prepared from the same animal. Treatment of crabs with RXR-dsRNA significantly (P<0.001) reduced mRNA levels for RXR and for vitellogenin as well as MF levels in hemolymph. These results indicate that, MF and RXR form a complex (MF–RXR) directly and together stimulate ovarian development in these green crabs. This interaction of RXR, MF, and ovary development axis is a novel finding and is the first report to the best of our knowledge.</jats:p
Abstract 4416: Combination of HSP90 and proteasome inhibitor is effective in pancreatic cancer
Abstract 205: BBI-608 enhances the activity of chemoradiotherapy in colorectal cancer pre-clinical models
Abstract 205: BBI-608 enhances the activity of chemoradiotherapy in colorectal cancer pre-clinical models
0001
A VENERABLE CROOK.
A few weeks ago there appeared
at tbe Mariposa one morning, an
old, wbite-beaded man'whose palsied limbs and trembling voice
filled the breast of F- A. Bowen,
the good natured manager of tbe
Mariposa, with a flood tide of compassion. Tbe old man had been
-out all night in the rain, be said,
And bis shabby old garments were
soaked through and clinging like a
shroud to his poor old feeble frame,
and when he opened up with "Pity
tbc sorrows of a poor old man, etc..''
there wus no car in the Mariposa
that could be deaf to bis appeal.
He said that his name was Veh-
-meyer, and that his home was in
Opbii. Placer couuty; that he had
been on a visit lo some little town
in tbis valley and ibat be bad been
set upon aud robbed of all his
money and good clothes by highwaymen; that be had told his story
to several people but was not believed
VHENEW CONGRESSMEN
Amusing Excerpts From Autobiographies of the Members.
BIRD'S OF MISSISSIPPI SHORTEST.
Ua-ll- a liar and a Half I* Le»«ib.
Other Hepi-esr-.latl.ea *tt-l Se R*tl-
rrnl-niln-.l* Mai Praia** Hla Wife.
tlblcas What la I'm.. *f 111* *****
Ur.
Tbe Congreaalonat Directory, contain*
lut,- the biographies of member* of the
Fifty-cU-tiHi cougrcBrt, written by theui-
eelve*, came out the otber day, say* a
Washington special dispatch to tbe
New York Time*. The uutobliigrupblcB
..r the uew member* are full of inter
-st. a* revealing thc frame of mind la
wblcb a iiwu Is whoa be lias Just become ■ full fledged solou. A new
member's biography la generally loug
and shrink* In size year by year. It
also contains many mere fact* about
CARNEGIE'S NEW MOVE I
IMPRESSIONS OF LORENZ.
Will Finance Project to Reform
Our Language.
a laratairraT* Strlklaa* Trlfc-
ul-. I* laillraa (-*»a.i-ltj*.
"America I* a splendid country, and
hose who Inhabit It arc- splendid peo-
|..*." was the ceaxtpKltenalve way lo
| -.'bleu E*Tof*Mor Lorea* ckated hut ad*
IEED OF FR0H0OH0IIO ALPHABET! *«*»" "» ■ **~ audience In Vienna oo
bla Imprt-swloua of tbe United State*.
■•j* the New York World.
Phuolo^-t- a.*. w*» ..«■ mm* j Tbc profrmor W1U BO,t *nU)I1J_tlc
Bate's Help Toward. UlrnJurlni
Obi* «"d ( hasclas the Spcakl*.
and Wrltln-r, or E**ltah—PraHBt ,
Statoa of the MstcaraL
Andrew Carnegie haa come to tbo re- ■
Ii.-.' of "the English language aa she la
spoke-" He has pledged hi* Qaauclal ,
supitort to a movement wblcb will
iln.nt American coartty,saying: "Anier-
teaua practice charity with the passiou
-.-..■:. which other people practice some
kind of aport. 1 am couvlnced that If
1 liad nafd that the orthopedic bo*pl-
tula In New York were Inadequate tbo
money for a uow oue would bare been
subscribed tbo uext day. 1 wit* inm-li
Impressed by the simplicity wltb wblcb
bring about reform aud correct abuse* , -i,,. president of the United States re
lu theH,Mtiklng and writing of English,' reived uie. " 'Are you tho fanioUB doc-
says a Waahlugton special to the New j tor from Vicuna? be asked. 'Let me
York Herald. shake bauds with you. Just tbis morn-
TUI* 1* lu pursuance of Mr. Carne- _* «* lleemwelt sj>oke of you' Then
, . j ■ . . c ii k th mJt-MM lie to d me the hlatory of bis family ~
Sie'. desire to tare English the prWl* j ^ . ^^ —J, _QVf ^ wa8
pal language of the world. The Unit. _ dort0|.i atltl toUi abou. 0_6 Qf his own
giep will be In tbe dlrecUou of reform ^^ Vfbo ,B „<,- atnus. Then be sbook
and simplicity. Member* of Ibe van- bauds ngnlu and went back to tbe Veu-
himself wblcb be thinks of public tu- ,,.,„ philological societies who bare] ezuclau •|ue«tion.
Me " , ,,**, * - tcrest lhau i- tlie case with the old _<#,_ laboring for phoiictic spelling and ; "Tlie uovdty of ahaklug band* with
go home and bad waikeo as lar as tavmbetm (be CKttlou of . p™uaclj.Uo0 alpha- : ao mauy people I did not kuow impre**-
Palo Alto, when be suddenly re- Tl„ lon_, btofrri|lhjr ,„ tho Uwk la ^ ^ Ur c,ril™ric.m intent in < rd me deeply. Someilme* I would u*
membered to bave seen an account; ._. of Sot(Crt itakrr, , „w ^^ j ™ ■™"™ "^*™?*roZZYh- .--*. i «- • train, aud
In his home paper of Mr. Bowen's ] (rom Brooklyn, but lu bis ease it i* evl-
haviug moved from Placer county j dently ihu egotism bul a dealt* to
to Palo Alto. He weul to Ihe post-1 boom the Biugk* tax wbieb prompt* the
office where he was directed to the; "-*' °-" *» -P*** nrinter's iui, 11.* blog-
la n Uiinl,
Ilenry Ol
disguised ai-gUllMUl
-ge theory.
i from llasalaalppl. Adum
iiiiitii St-niitor Iturtun of
ll of biivlug the aliorti*.
r iu die Bat, iiiiiioir* w
i ouly a Hue
rnph,
for tli
A new ma
Ityrd. lias r
tht* distinct* Ii
iiutoblogrnpli
three hues long 1.- :■!'-
and a liulf aud 1* a* follow*:
"Adam »vnl. IX-moi'mt. of I'litludol
igbtb
tbe mailer, and be will finance the on-1 « " *r»l"; fud '"*; eu*:iu1e*r al,d fl^
Uii.Il would li'UVi* Ibe i-ligilit*. i-iiDIl' Up
den.kl.« untilI IU. eomplclon to tb. ■ ^___£"_£. n..U a.o.
extent of $10,000 n year.
llaripon. He said if he could onl;
get enough money to pay his fare i
home he would be everlastiugly i
aj rate ml nud would return the
amount as noon as hc reached borne. \
.N'otv Mr. Bowen lived for a long.
time in Placer couuty and had ol-;
leu heard Mr. Vehmeyer spoken of
as a well-to-do man, but had never j
seen him. and when this old mau
■mid hc wus Vehmeyer and told an
other wi-v straight star>". be bad no '
occasion to doubt him. He readily
cousented to loan him all the money '
hc wanlcd, and insisted on fitting
bim out with dry clothing but the
-old man was anxious to be on hisl relate* In hla biography how he defeat-1
N. Can-cuter, lie publican.
change his clothes, but took the; «n*™» and add*. -Mr. ltottinaou'*
first train to tbe city. Mr. Bowen : *"°,c *" ^ f^K^^TZ*™ '
- ; any Demtx-nttlc nomluee for (*<ttigrt**a
* In the Mutt- of Arkauna*. aod Ur. Car; '
A meeting of educators, prcaided over
tiy Meitll IV've.v or Albany, was bold
In Colunil-fn unlveralty. New York, on
Feb. th Till* committee dlm-unned tlie
matter thoroughly, but tw fur as can
be li'.iriiud no tl.'iiui!-' netlon wan deckled upon,
\\. T. Iliirrlt. Tulud States etimmls-
-i.itii-t' of i-iitie.iT.iiu. who wan luvlted to
attend tlie uieeilug. baa Imm-ii miiiic
aWiire of wlint took pint* nud of Ut"
pranmt status of the movement. He
pblu. waa eli-i'iiil in tbe Fifty
eoiigr**!**. r»*e*'l' tltg 3.081 vote*."
Alinoa. a. ,l»r. are lb. bl.wapbl-. | «-.™: proaoanelDA! alphabet
of,*_*_* ■;' N°r" '■""";• fi°ti t«rm.«i..i«,. L-iub *.»»«. ■».
all of ■lr-lnl. Kln..ld ot Netiniaka ; Tbo ,„„„,„„„„ _
ami kellber and ilc.N.r, ol -la—cho. ^ f(-|em| ^ „_ mo|1J phl|olog.
"*"*- . „,. - i l,-.l aoclettes. and when the uiattor waa
ut „.,,,,s... .i,u iihuku «u umur,: lint muer Ufw amD an- not ra> ..'It re- . .. -# u. t.m^
bimout»i.b dry clothing but the strained. Joe T E^~*LS£1 Jjj" %££%%£__ _.
a I easarv mouey If tbc project were bau-
way home and would not wait to|.-«aWiJ'» _*__**__*!_** __?t™______\*i^{rri_w*mniH mw
"At ps**eul a person la riot able to
tell the prenutKiMlioii of a word that la
having give,, bim abou. seven dol- IT* ~i no. «.n,n»n been... ot ,be tact tha,
me lu the street and do *o."
ProfeMsor lxireus remnrked for the
uciietil of tlie medical stDtHtUl pi*e**4'ttl
(hut dinner ut tln-lr club cosw lea* tiiau
ll din-* to gel one's boots cleaned lu
Chicago. He did uot enjoy tlie dellcii-
«Im IU AnuTk'ii. During the sumplti-
ou* bulii|Uota glvi'ii til iu lie ol'ieii pined,
he mi Id. for ibe boiled luff und kraut
of huiiu'. Oysters wew aliout the ouly
Anierk-an dialt Iw ruull}' eared for.
He tbluka ll very tine ibai American
attiik'iiia do not drink or tight, but de-
mi them-u'lfe* io study aud sport. lie
told tint Vlenua tlnctor* that lu America niir*.— nr.- treated like ladle*.
l»r. lxin*iiz tbiuk* America'* women
are rvmarkabl* fur their education.
eleven--*** tiud ariUtle last**, but be
doe* not think they can cook a dinner,
uud be lufers that that may be the reason why they are *uy wbeu marrUge
tacouc-enw-d.
HELEN KELLER'S PLEA.
iany letttr* have several BDd la the
'■ ca*e of the letter 'a' Ave or atx-pro
elected to ,».' IW****! rr'l'aTnr fa^X".^ SS?
F.nally hc wrote htm a letter, more ; i-onareM -lo the mklat ot au all dii, ( .,,lUu„ „„, ,„ K. _^ „,. Tam.
to know if he had arrived home; _»*«£* ■*• ___*_*i ," '■ >n many wop*, that pl.llolostat.de-
aalely, than for any other reason. I ,Mrt- Milton J. tranlel. of c.litornl. S-*-** wlb-1 dirferently or
and-in reply go, a note from Mr. j %~*~ \^.£_*\_ _%«» «**■ .... »■„-they -,n,,„.
—Fuke tbe wort* 1br*ngli. It I*
lars to pay the expenses of his trip, j pemer'a was the amallest.
Time jtassed and Mr. Bowen) Minor VVallnce of Arkansas
heard
I .u..m> IHI-.4 Olrl 1>ST*B Relief Far
1.1..... l*t*rta**t*".
M.-. Ileli'ii Keller, known tbroagli-
I out tue country u* the girt born deaf,
tsuinb and bltiid. wbo baa achieved a
| brilliant education, wis the center of
attraction at a lv**iirlng held in tb*
I statoUoaae at Bostou the other da; by
education.
ii • .•_ . i_ i. j t anicie tuai ue vuieti i*»r -..lueuiu u
\ehmcyer saying that be bad never | imi HDd b^ j^,, prolIIinenUy Wenti-I '■" '" " "'" *^7^"" _" Z- tuo legl-tatlve cuwiulttee on edueaUon,
been in Palo Alto, nor tbe Santa ^ wltb „ llK^__ ^ -*, jr«d ^ «h*« ^W l^a fdgn^ ^ ^ ^ ^ ^ The ^^
Clara Valley iu bis life, and certainly was not here on the occasion
aaTcntioned.
Then .Mr. Bowen began to think
tbiavgs.
One day last week, a sister of Mr.
Bowen who lives in Sao Jose, and
since.
Franklin E. Brook* of Colorado een-
"e**«* tti*t he "la a rn.-iiil.er of several
qoaalpoblle orxanlzaihiiis'' and tbat be
"haa don-- a t-ota-ttdt-rable amount of
**.liliTiiil and mla-cellaneott* literary
,tl by lining the sign determined upon
tt.r ate tlrat two letters uud tbc letter
'o.' for InsUtuce. th* EogllaJi pronuu-
fi.-.ti.ni of the word "poat' -< poust/
TtM- accent on,
was for th* |.nr|.i.-i- of determining the
advisability of appointing a tomml*-
*i.... to lnv**nl*T*te the eoodltlon of tbe
adult blind. Mia* Keller said In part:
It i* terrible to he Wind aud be sin
who happened to be in Palo Alto j ter*7t „t^-wn^^ -,
on the morning when the old man tereatetf lo atblaru*-* aavd lor thwey-swrai **^n wl^^ ™* *° , ,^T\ raBBBalbaC the dlst:
appeared and heard bis tale ol woe. j pultrf the bow o-o-1. Ma claa* er—." ■*** *" ^'"f, Ti____T P"*"" ' •»• —"
appeared
-answcre<i a ring at her door and con
fronted thc same old man with bis
palsied limbs, shaky voice, "Pity
the sorrows, etc." He opened up
negotiations by saying that his
name was Pfister, father of Henry
A. Pfiater, county clerk: that he
bad come fb see his son and found
him out of town; tbat he bad been
held up and robbed and was trying
to get some one to help bim to get
back home: thut he was a stranger
and—but at tbis point Miss Bowen
excused hcrtwlf for a moment. She
sent another member of the house-
We profwuoce ir -po-t. i*r ■—or. oo . „_ -. f ,-,,, ymj
„ vowelht almeat lt>*L That L. du- | ««* 2»" JJ rfMtto|l to u
„ | to tbc -art»oliai«'ani*-or *ur land, wbo | ^ TMf y_ ^ue.aan become* a
bunteu brcauae tbjpy csmaot oae IL
of many blind
p«r-*ons | bave> auown wfco- after anUb-
lug i '■'■: edueaUon could find no n-Mui
of supporting themselve* because bo
oue helped them to Und po-dtlon* In
wblcfa tbey coald turn what they bad
been taught to practical use.
"The greater their ambition lo do
utw-ful work th© more cruel their dlsap-
poluttucuL If thl* coiumouwealth will
pulled
A man wbo la pn.o-J **T bu wife I*
Henry T. Usdatty. a arw mau frosa
Can-ollton. IU. Sat take* adi uma,,*,- *i
the stpace atforded for til* aun-t-ssgra
phy to say a good wonl for ber.
"Mr*. Balney." be- Bays, -la lul.********-
ed in phllantbroplr wnrk sum! wa* fur
several yeura aecrctary of tbe llllanl*
State Confervuee uf Cbarltkra Sbc Is
at present a meiutier of tlur board of
trustees of tbe St. Ctiarlc* Boys' liuut*.
an Institution which Ita being largely
eudowi-d by Jobu W. *.nt.-i aud Sum
. . ■, , .. owed by the move for tin* iilixlialM't.
■.a,fsssxs^-t t.r .u «*i s b»g« «" 5 -r»_ffi
Mr. Italne) tlilnk. II **U .« add . to W what -* be do.« aloi* ...1.
word for lilui,.-lf. tie aaya: "Mr. Ital-; bne.
{A Well Dressed Man Always Commands a
■u.-.i just a Hid* |
Hon) i
RA*aisf*rt We *,m lo d'
llVJSpa-*\. beXi.r tbmn .nybody
are a few ol the new rtyle* which will mako jo" a i
Stoell Spring Suit j
Norfolk Jacket, Fly Front Biwli*e»Cutaway Frock, .
Throo-aad-Four-Button Cutaway, Doul.lo-Hrcaaioa T
Sack. t
F«hion Plates Direct from New York Every Week j
MERCHANT TAILOR
On Circle Oppoalle Oapot
8-^ *»v ■*. *»v-»a>-ar---^-**>■»** ^^.-^-^^*^
a l->* \r- • LAUO I Dll Oa Circle Oppoalle Oapot ft
VIOLIN CLARINET
TROMBONE
CORNET
PIANO
TERPS1CH0REAN ORCHESTRA
Music to suit all occasions Dance music a specialty
Il will pay you lo inquln, H. P. Harrison. Mgr., Bo* 501. Palo Alto
wmsss
IQ GRAND!
Salt Lake City.Lcadville, Pueblo,Colorado Springs, Denver
Omaha,Kansas City, St. Louis, Chicago and all Points East
ConoccUng at Ogden I-nlou Depot with all Southern Pacific Trains
Only Trans-continental line passing directly through Salt Lake City
cr-tonally conducted Tourist Excur**ions daily from California
to St. Louis, Chicago and Boston
Choloo of throe acparaU' route* tlirt.iii.-ft the Rocky Mountain*.
Through Pullman and Ordinary Sleeping Cars
To Denver, Omaha, Kansaa City, Chicago and SL LouIb WiTllot'T rbange
FlCEK KKCLININ'O CHAIR CARS
DINING CARS—Service a la Carto ON ALL through grains
I'"! K.ll- .. I'... I. In
rated Uooka of Travel, cttt, -n ni!_-r ol or write
a tM.. Sao Joae. CaK
Palo Alto and University Liverv and Feed Stables
Vaoderroort Broa.
Phone BUoV 20
*• hurry ap and uot tirag It out.
-There an k-i* of ttalnga to tW cor-
re-rtt-j Tbr great re-aall or tbla ali.ua
bet will be l*> change tbe spotlUag ot
word* to tbr wny tbey awntf tphoiveUc
arpe-ntfag). ''I*roi-T-iiiiin.-' WftHuial l«»rt*air-
tlme* correetay *pelletl *programB*e.'
bot tt is met** generally; speltod *pro-
-rrain.' We save time isud ***»U eor. ; JgJJJiJJ", cowwlaalou to place tbe
rectly the word we proiioau.ee. bti|1(I ,n poBiuong <,( «.« *up|*ort,
n'tacfc arc ether alight aud groat ra- I w||| ^ u0,1)g ^^ ,bi„g*-beiplng the
form* In EuglUb that there Is a- desire I mv^ ^|wto§ lUl4.if of the buitleu of
- e*ta_bUsh, btu ^J^™*™™_Z I eartug Tor tbem aud aetUng au example to other slate*."
t.ii-uila-rs. aaya a Waalilnglon apeclal
Um* Sew York World. The prv**li*ent
bold to listen to thc old man while ■ „*j tt a clone atudeuL a thorough law-,
she telephonetl to thc police station i yer and enjoy* a large practice la*, SHAW S LATEST fchrUblUW.
and in a few moments an officer ap- j Greene aud atljoinlug eouutkr*. EIi» ^^^ B Forth tm V,P^ .,
pearetl who took the poor old marri ea™ can be found In alnio-t every roj » *—*""„ «,*.„..-.
Shhi, p_M limbsetcto theiu^ £^J?J^££\ _^_l_^S__%_Z_t_Z
lock-up. | ZSrVta tea contribute a* mtKb a*! i»*« • ^ * ^ft _^_S
He is evidently a smooth old con* | _iiy Uwye, ,uWhtU mlMftiut u» Catat-I- War*. b»* apr«il to th. eabttatj
fidcncc man who studied out the lay { taw of ti^atatc."
of the land carefully before he be-; M.inin J. Wade of i«wa make*.
gan operations. He will have a ■ known Ihe fact that "alut-e bla rteva
chance lo explain to the San Jose; Hon to tbe bench he hs* ai.-udfa.tly re
authorities in a few davs. bow he ! rtmd to make eampaigu si*-, lies d.-
SU -j* «••£•»*-£ - rr tfi'Sft ~«r
Placer COOnty and Mr. I nster ol [lll11H, f„r )(-ur!, to iK^*ome n ...ndldm.-
Santa Clara county at one and the r(>r ■wmr:WfJ(- Uo, ,„.nti*ienilj ndiM'ti•"
same time. The aulobloKnitihy at Arscue I'. I'n>
of l*ul«lauu 1-eglns lu tills gttalnl unit
[old fuabiiniwl ___ "Arwia P. PwJo
Deuoeral. of Luke Cbarle*, wu* born
Hi-,- n;. ism. near Lalia ibiii'le*. Cal
: vusk'u piiruii. of itie mairlaw nf Hi'
fan Piijo nf TitrlM-tt. rranoo. to Ml**
r-:ioli*e M. Le Itllie."
Auity-t 11 Jitekwdu of Ohio give* thl*
j account of tils eouiutorvlal pttrnulta:
"Slnrted out lu tbe aUatt veudlUK
: buslne**. which be followed until I8B*.
| Since ibeu ba* been engaged In the
NOVEL FISH DINNER.
Th* Hnateaa Wore Wonderfal Flat.
Seal* i..." H-
Mla* F.llxahetb Tyree." leading worn
en of "The Earl of I'awtnekef conj-
pany. gav* bor fUli dluuer the other
night at her apartiuent-i In New York
Tliere were twelve gursU-
Kvcrythlng. from the miniature lake
in tbe middle of the table to thc won
,_ , -Irons fiah scak' gown woni by the
luermulds. wiy* ihe New York World:
The lake wus lulialalii-tl by scores of
hungry goldfish nud by mliiiuturc
by ri-adiug th« following fniai the pi'i> '
of t^-<-rHai*y Shaw:
"Oo **k pap*." tbc maiden said.
The youna man knew la.-r papn waa d**ii j
Hi- also knew the life he h.id.lt -'
Red it: Laundr
D)t-AM| . HcNAIR. Agent
The OAK HMsss) SHOP 1*0 University Avi
'l'lueintiono IliaoIt 106
F. Luscher
Carriage Painter
B.uerlenc* In I'.rla
.ad New Yt.rk .hnp.
Mullen A; ...rra. BUI IH^h.trr.
Palo Alto Home Bakery
First-Class
BREAD, PIES,
CAKE, ETC.
~~r>Mrs. C. £ Bartholomew
Low i'.-iiuf Again.
WHO KNOWS
Commencing Fobruary 1'ith thu
Union Pacific will make the very low
rate of 433.00 from Chicago, *.'l*'.t*0 from
St. Louis, and a**5.00 from Omaha to
Sao Francisco, Lo* Angoloa and otbor
points In California. The rate* from
mhlc Haa ; otbor easlorn clUc* will bo nduc*-d In
ched thc pro)*orllon. If ono wish.** to hrln-r
WHERE SHE LEARNED ENGLISH.
The following clipped from a recent number ol the New York Sun,
nine interest Stanford people:
l.lc.itinr Qatar. Tully. author ot
"The Biography of a Prairie Oil I,"
said thc olhcr day when a tamuus
critic enthuMastically prai-ed ihe
puritv and finish of her I.nglish
•-That's an easy thing to tell InslBtent
odiee Hifkt-r-i." uiuned Mr. BaoaeveU ai
be ortleretl a bunch of cople* of Seem
tnry's Shaw's effusion * truck off *n a '
lyDetvrltt-r.
Tbc prvHideiit now la nnxlotia to hear
front Kecrelury lluy lu verse.
■Iinrk*."wliiik-tt nnd ;..:.-.•■:- of wood.
lu tlie iuouUih of the lutlor were pearl
pin*, for which the men Halted. Tlie;
Himvi'iilra fur ilit- woiiii-n tv«*re conilj
meuu Waa prinietl on]
ills of tiny ynt'his, whtcli
When IIU Kidney
Fntttencd nnd
C.ironlo Atafie? If It Haa It Irs. tholr nilallroB or friends from any plaon
Incurnblc by Anything Known in tho East, all thoy bavo to do la to
Iv.-tpt thc Pulton Compounds. '■ make a do posit for lho amount of tho
Wo Are Thc Sola Afionttt. ; tickot with Mr. I). W. Hltehcook,
i General Agent of fh« Union Pnulllo
aa.nev.daaeaof.bauni.si.alel.araetaror.bs, ftaSlroad ?™*£*1 N°' } ^K""^
Pulton Oamiaound* that *vmiiany doe* not pub-' «roct, Nan Friineistio, who will I'lieor-
llnli or Invito to.Hmtiolal* aioopt those report*, fully tolagraph the order nml atinnil to
m-w t'i- "aa of tta- N-w Vork Yaclit, _„„„ ,„ ,,,„„„, „__ ,„„ ,.„ , ;,„ , -«i,l.li.tor-*r-»r..
.-hi i. iii lie ii.iii it tire nke. *._ .»._ ,h_._,_ ..... .11..0 io i.. innnrv .'.'■■"
"(Jlicer, isn't it? I went to the: ,lwuafuetun* of muslin uud ilunnek'llr
Univcrsitv of California and to und-Tgartiietili*. with factorle* at Kiw-
Stanford, for Special courses: but | mont. Sandusky. Tifllii and Clyde
*,•-/•!Ilea Far Ki.*it-r.
There are pretty things In En*t*'i
ncxcltle-i for the ctilldreu. Tliey are In
tbe form of Easter egg* la wood, with
decoration* on tbe outaide and Inside.
treasure* In which chUdren delight.
Bay* the New York Tla****. One egg
contain* a tiny tea *.t in red *u*l
club. In tbe uilutiilurc lake.
Tin* gown worn by Slii** Tyree wim
of eliiiugi'ubk- green silk, covered with
thotiMiind* of opalescent scales. It lt*
*a!d to have cost tvNKi.
because i had no high school de- Jatnr* Kennedy of Ohio la proud of j wbittm anotl-er one In bine aud whit.
Swunla and I'lossahare*.
Instead of beating swords Into plow
*ban*« uow the Doer* of South Africa
bave thrown their sword* to the *crap
beap and orden*d tbelr plow* from
Amerieau di-ak-r*. saya tbe 1'bllade!
cree thev wouldn't admit me to any ! his ramtl*-. Ilestty.: "All bla alx broil, j ^ , thiru bus a toilet set. a wmab-
i- .1 kl *tUe Kncli^h courses 1 I rrs are promk-iit lu tbe Iron world, the ^^ an_ pttcher of miniature alae ami
of the higher hnglish ««^»- >. ol(Jw(t> j0li<l!J. MuK tll0 loul4!llB «„.; _ ,,_., f.iMm tant_ ,n auotll„- ,(f th.
Frldlejr, a rosldsot ot Loa Oaloa,
bsTii.j ehto-n.- kldoey disease (nrtgat's Dla-
ra-ei had. Ilka evar-fbodr alaa, found all treat
taaot futile. Ha i-ommaoeea on Fulton's Renal
Componad la Fabraarj. ■», aad Oft I*etsei=t.-r
rOofta* aa***> year reoorted tb* total dlsap-
peara-ut* ot the diaeaa*. Uawrit** that n*t*»
c*ionl tUtoeo loaads la weight and la again
1*1 ;rir^or.^u:r^Jrr.i
reatiltrtl Una ihrunlo Blaife, alleietl to lie I11.-11:-
hllT Herat. ..othorraeoVar, la. oa^laeurn* -ner; Of Call UpOO It. Datim-berg, Agent
bla till tt* tu-ventot tba Fulton Oempouot!*, Southern Pacific Company, Pulo Alto,
reported by John* 4 Johnson, th* ague I* of Ihe California.
Pulton Compound* I* Loa Oatoa:
baa agreed to altip 17,000. It Is an hi. j
bad to go into iicw*.pnpe. work and
get my Bngllah training in that
school."
PETITION LIBERALLY SIGNED
The Maylicld correspondent of. the n.
