17 research outputs found

    Chapter 7 Nutraceuticals and inflammation

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    The chronic state of inflammation is widely associated with number of pathologies including asthma, pneumonia, cardiovascular diseases, metabolic ailment, inflammatory bowel disease, arthritis, neurodegenerative disorders, and cancer. The conventional drug therapies including nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids have certain limitations, mainly related to their adverse effects and high cost. In this regard, there is continued focus on alternative therapies, including plant-derived components to prevent or treat inflammatory conditions. Food bioactive ingredients showed promising health effects with favorable safety profile and relatively low cost. In recent decades, they are being extensively evaluated for their anti-inflammatory effects, and further investigations on these bioactive ingredients will result in the development of effective and safe food supplement-based therapies for chronic inflammation. In this chapter, the immunomodulation and anti-inflammatory properties of dietary fibers, pre- biotics, probiotics, polyunsaturated fatty acids, polyphenols, and spice-derived bioactive components are reviewed

    Cocculus hirsutus (L.) W.Theob. (Menispermaceae): A Review on Traditional Uses, Phytochemistry and Pharmacological Activities

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    Background:Cocculus hirsutus (L.) W.Theob. (Menispermaceae) is a perennial climber distributed mostly in tropical and subtropical areas. The main aim of this article is to collect and analyze the scientific information related to traditional uses, bioactive chemical constituents and pharmacological activities. Methods: Scientific information on C. hirsutus was retrieved from the online bibliographic databases (e.g. MEDLINE/PubMed, SciFinder, Web of Science, Google Scholar and Scopus). Information regarding traditional uses was also acquired from secondary resources including books and proceedings. Results: Different plant parts of C. hirsutus were reported to be used for the treatment of fever, skin diseases, stomach disorders and urinary diseases. Alkaloids such as jasminitine, hirsutine, cohirsitine and their derivatives along with a few flavonoids, triterpene derivatives and volatile compounds were reported from whole plant or different plant parts. Extracts were evaluated for their antimicrobial, antidiabetic, immunomodulatory and hepatoprotective activities among others. Conclusion: Although widely used in traditional medicines, only a few studies have been performed related to chemical constituents. Most of the biological activity evaluations were carried out using in vitro evaluation methods and only a few studies were carried out in animal models. In the future, properly designed in vivo and clinical studies are necessary to evaluate the pharmacological activities of C. hirsutus along with bioassay-guided studies to isolate and identify the active constituents

    Manifesto of one's mastery in wilderness in Jack London's 'The call of the wild'

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    The call of the wild is a novel about one’ s mastery in wilderness. A domestic male dog which become a sled dog and reach it’   s mastery through the instinct of his ancestral wilderness. What are the difficulties he is going through his journey is the entire story. He did not find himself adapting to each difficult situation, but understood it and acted accordingly. The author mainly speaks about the survival, pride, transformation, trust, violence, mastery. We all know how to live our lives, but we cannot accept difficult situations. Here the author speaks about the survival of the fittest, Darwinian theory. We, the readers of Charles Darwin, are subjectively aware of the concept of human evolution and natural selection for the survival of the fittest. We can see Darwinism and Nietzscheism in his novel “ The call of the wild”    . Author says that one who is adopting every circumstances and acted accordingly will be the master on his field. The protagonist male sled dog points out that every human being in the universe must remember the power of their ancestors.&nbsp

    Seaweed minerals: unlocking functional food potential from an Indian perspective

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    Abstract Minerals and trace elements are thought to be necessary for human nutrition, and seaweeds are well known for their accumulation capacity and the rate may vary based on the locations. Green seaweeds are recognized for their iron and magnesium content, whilst brown and red seaweeds prefer to accumulate manganese, iodine, sodium, potassium, and zinc. These properties provide significant opportunities for the functional food development industry to create new ingredients and generate employment. Additionally, certain seaweeds are considered as potential candidates for addressing the iodine deficiency through regular consumption, thus seaweeds hold great potential as functional foods. This review examines the role of minerals in seaweed farming followed by their impact on seaweed growth and nutritional value, the health benefits of mineral-enriched seaweed, and its market potential as a functional food. It also discusses about the limitations, challenges, pathways for popularization, and future opportunities for seaweed as a functional food. Author name: Please confirm if the author names are presented accurately and in the correct sequence (given name, middle name/initial, family name). Author 1 Given name: [S. Shek Mohamed] Last name [Ibrahim]. Author 2 Given name: [R. Suhail] Last name [Haq]. Author 3 Given name: [S. Dinesh] Last name [Kumar]. Also, kindly confirm the details in the metadata are correct. The author's given name modified accordingly. Graphical Abstrac
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