59 research outputs found

    Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa

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    During this century livestock production has increased massively through the improved ability to diagnose, treat, control and prevent certain diseases. Despite these advances, disease remains a major constraint to livestock production and welfare throughout the world. In many instances, this is a result of failure to properly apply methods that are already available. TrypsChemo is an expert system that attempts to aid the application of veterinary knowledge to disease management. It has been designed to maximise the effectiveness and cost efficiency of the different trypanocidal drug regimens currently available for prophylaxis and treatment of tsetse-transmitted bovine trypanosomosis in Africa. This paper describes the design of TrypsChemo, the properties of the system, and illustrates how it can be used to support decision making for trypanocidal drug control. The system is currently undergoing a structured evaluation by potential users in Africa

    Paper electrophoretic studies on the relationship between the free amino acid content and regeneration in planaria, 1965

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    A comparison of the regenerative activity and the amino acid content was made on 4 transverse sections of planaria, designated as Sections I, II, III and IV. Transactions were made of 100 animals and these were allowed to regenerate. The amount of regeneration of each section, time involved, and number of abnormal head regenerates were observed with a small stereoscopic microscope. Thirty additional animals were transected and samples from these were analyzed for amino acid content by paper electrophoresis. Regeneration proceeded at a faster rate in Section I and there was a larger number of free amino acids in this Section. There was a much larger number of abnormal regenerates in Section III than in the other sections. This section contained only 4 amino acids. The free amino acids present in all the sections were lysine, arginine, histidine, glycine, alanine, leucine, phenylalanine, tyrosine, tryptophane, glutamic acid, aspartic acid and cystine. Experimental data seem to suggest a relationship between regenerative activity and amino acid content in 4 transverse sections of planaria

    The Case for Admitting Evidence of Refusal to Take a Breath Test

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    Critiques the practice of Texas courts no longer considering a refusing a breath test an admission of guilt. The author points out that chemical tests for intoxication are within the ambit of the self-incrimination privileges of the United States or Texas constitutions. Thus, there is no longer any barrier to admitting evidence of a defendant’s refusal to submit to tests for intoxication. Such evidence is relevant and not privileged. The author concludes that any continued refusal by Texas courts to admit the evidence would be irrational, harmful to the public, and against the great weight of authority

    Addicted to Mansfield: a glimpse at the Ruth Elvish Mantz Collection in Texas

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    This chapter discusses the Ruth Elvish Mantz Collection in the Harry Ransom Center at the University of Texas at Austin. Mantz wrote the first biography of Mansfield in 1933, in conjunction with Mansfield’s husband, John Middleton Murry, who was brought in as a co-author by the publishers. The finished biography was not what she originally intended to write. She spent the rest of her life writing numerous unpublished manuscripts reworking the events of Mansfield’s life into book form. All her papers are now in Texas, and offer a fascinating insight into Mansfield’s first biographer

    The catechism of man. [electronic resource] : Pointing out from sound principles, and acknowledged facts, the rights and duties of every rational being.

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    Last leaf is "Impromptu to Thomas Paine," a poem, signed "A Republican".Price from imprint: Price Sixpence.Sometimes attributed to the Rev. James Murry, to Thomas Fyshe Palmer, to Theophilus Lindsey (e.g. in 'A reply', as "The Reverend -s-y"), or (wrongly) to William Vaughan (e.g. in Evans), or to Benjamin Vaughan. Author information from MH-H; not found in any of the main reference sources at Ldw. Eaton's address is 81 Bishopsgate St, from which he moved in November 1793; 'The catechism of man' was reviewed in the 'Analytical review' for 1793, p. 331Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library

    Katherine Mansfield’s debt to Chekhov.

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    If one examines the various critical studies of the work of the short story writer, Katherine Mansfield, one discovers the name of Anton Chekhov frequently mentioned. Some of her critics simply announce without being more specific that Katherine Mansfield probably was influenced by the work of that great Russian author; others go so far to accuse her of as plagiarism in connection with him. On the other hand, Katherine's husband, John Middleton Murry, who was probably her most intimate companion and thoroughly familiar with her work, fervently claims that his wife owed nothing to Chekhov

    The winding road to regenerating the human heart

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    AbstractRegenerating the human heart is a challenge that has engaged researchers and clinicians around the globe for nearly a century. From the repair of the first septal defect in 1953, followed by the first successful heart transplant in 1967, and later to the first infusion of bone marrow-derived cells to the human myocardium in 2002, significant progress has been made in heart repair. However, chronic heart failure remains a leading pathological burden worldwide. Why has regenerating the human heart been such a challenge, and how close are we to achieving clinically relevant regeneration? Exciting progress has been made to establish cell transplantation techniques in recent years, and new preclinical studies in large animal models have shed light on the promises and challenges that lie ahead. In this review, we will discuss the history of cell therapy approaches and provide an overview of clinical trials using cell transplantation for heart regeneration. Focusing on the delivery of human stem cell-derived cardiomyocytes, current experimental strategies in the field will be discussed as well as their clinical translation potential. Although the human heart has not been regenerated yet, decades of experimental progress have guided us onto a promising path.SummaryPrevious work in clinical cell therapy for heart repair using bone marrow mononuclear cells, mesenchymal stem cells, and cardiac-derived cells have overall demonstrated safety and modest efficacy. Recent advancements using human stem cell-derived cardiomyocytes have established them as a next generation cell type for moving forward, however certain challenges must be overcome for this technique to be successful in the clinics

    Murry, John Middleton, (6 Aug. 1889–13 March 1957), author and farmer

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