232 research outputs found
Extended Work Schedules and Health: Role of Sleep Loss
No full textProf. Van Cauterinfo:eu-repo/semantics/nonPublishe
Effect of 1 week of sleep restriction on testosterone levels in young healthy men.
No full textJournal ArticleResearch Support, N.I.H. Extramuralinfo:eu-repo/semantics/publishe
Phase-shifting effects of early evening administration of agomelatine in healthy older adults
No full textSymposium :The effects of melatonin analogues on sleep: implications for treatment of insomnia and circadian rhythm sleep disorders.info:eu-repo/semantics/nonPublishe
Sleep deprivation: subjective sleepiness, cognitive performance, electroencephalography, metabolism and endocrine function
No full textDr. C. Cajocheninfo:eu-repo/semantics/nonPublishe
Diabetes
Get PDFShift workers, who are exposed to irregular sleep schedules resulting in sleep deprivation and misalignment of circadian rhythms, have an increased risk of diabetes relative to day workers. In healthy adults, sleep restriction without circadian misalignment promotes insulin resistance. To determine whether the misalignment of circadian rhythms that typically occurs in shift work involves intrinsic adverse metabolic effects independently of sleep loss, a parallel group design was used to study 26 healthy adults. Both interventions involved 3 inpatient days with 10-h bedtimes, followed by 8 inpatient days of sleep restriction to 5 h with fixed nocturnal bedtimes (circadian alignment) or with bedtimes delayed by 8.5 h on 4 of the 8 days (circadian misalignment). Daily total sleep time (SD) during the intervention was nearly identical in the aligned and misaligned conditions (4 h 48 min [5 min] vs. 4 h 45 min [6 min]). In both groups, insulin sensitivity (SI) significantly decreased after sleep restriction, without a compensatory increase in insulin secretion, and inflammation increased. In male participants exposed to circadian misalignment, the reduction in SI and the increase in inflammation both doubled compared with those who maintained regular nocturnal bedtimes. Circadian misalignment that occurs in shift work may increase diabetes risk and inflammation, independently of sleep loss.P01-AG11412/AG/NIA NIH HHS/United StatesP30 DK020595/DK/NIDDK NIH HHS/United StatesP60 DK020595/DK/NIDDK NIH HHS/United StatesP60-DK020595/DK/NIDDK NIH HHS/United StatesR01-HL72694/HL/NHLBI NIH HHS/United StatesR01-OH009482/OH/NIOSH CDC HHS/United StatesULL-TR000430/TR/NCATS NIH HHS/United States24458353PMC403010
Impact of sleep loss on glucose metabolism and appetite regulation
No full textDr. H. Landoltinfo:eu-repo/semantics/nonPublishe
Effects of sleep loss: from behavioral to physiological
No full textProf. P. Peigneuxinfo:eu-repo/semantics/nonPublishe
Sleep Quality & Diabetes: An Emerging Piece of the Puzzle
No full textinfo:eu-repo/semantics/nonPublishe
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